Crime cases from snatch thefts to murders, are becoming increasingly common in Malaysia according to the database of the Royal Malaysian Police （RMP）, the current overall Crime Index in Malaysia was 147,062 for 2013...Crime cases from snatch thefts to murders, are becoming increasingly common in Malaysia according to the database of the Royal Malaysian Police （RMP）, the current overall Crime Index in Malaysia was 147,062 for 2013 compared with 65,237 in 1977. The database also revealed that the number of property crimes reported in this country has always exceeded the number of violent crimes. Although in 2013, crimes related to property are higher （117,687） than violent crime （29,375）, the gradual increase in the latter does worry Malaysians. Likewise, Malaysian Government had implemented a ＂safe community＂ concept, inspired by the Malaysian Crime Prevention Foundation （MCPF）, a non-government organization, as they were concerned that the threat of violent crime and non-violent crime would eventually reduce the quality of life for many individuals. The concept is very important to the public as it is perceived as improved safety for the public with less crime. This study analyzes the public safety through their perceptions on the effectiveness of the policeman and suggesting few prevention actions against crime. The data were collected using a self-administered survey questionnaire. Specifically, this study focuses on the more developed states in this country. From the cross tabulation analysis, the majority of respondents agreed that the police are effective in controlling crime. Approximately, 72.1% of respondents felt that the police are efficient in controlling crime.展开更多
Background: Deep brain stimulation (DBS) is an established treatment for patients with advanced Parkinson’s disease (PD). Reports show continued patient satisfaction after surgery despite not maintaining clinical imp...Background: Deep brain stimulation (DBS) is an established treatment for patients with advanced Parkinson’s disease (PD). Reports show continued patient satisfaction after surgery despite not maintaining clinical improvement as measured by evolution scales. Objectives: The present study sought to explore expectations and level of satisfaction in patients after DBS surgery with a semi-structured questionnaire and subsequent correlation with functional scales, Quality of Life (QoL), and motor and non-motor symptoms. Methods: We performed descriptive statistics to represent demographic data, Wilcoxon rank tests to determine significant differences, and Spearman correlation between the applied scales. Results: We evaluated 20 patients with a history of DBS surgery. 45% were female, with a mean age of 55.7 ± 14.15 years, a mean disease duration of 13.42 ± 8.3 years, and a mean time after surgery of 3.18 ± 1.86 years. Patients reported surgery meeting expectations in 85.5% and continued satisfaction in 92%. These two variables showed a significant correlation. Conclusions: This sample of patients remained satisfied after DBS surgery, although we found no differences in motor and non-motor clinimetric scales. Further studies are needed to confirm the importance of assessing quality of life in patients with DBS.展开更多
为了提高电能质量扰动(power quality disturbance,PQD)识别结果的准确性,笔者提出一种基于改进灰狼优化算法(improved grey wolf optimization,IGWO)优化最小二乘支持向量机(least squares support vector machine,LSSVM)的PQD识别方...为了提高电能质量扰动(power quality disturbance,PQD)识别结果的准确性,笔者提出一种基于改进灰狼优化算法(improved grey wolf optimization,IGWO)优化最小二乘支持向量机(least squares support vector machine,LSSVM)的PQD识别方法。通过采用收敛因数指数调整、自适应位移和权重动态修订等措施对灰狼优化算法进行改进,得到IGWO算法;以PQD信号的9个特征量为支持向量、7种PQD类型为输出量,利用IGWO算法寻找LSSVM的最优参数,建立基于IGWO-LSSVM的PQD识别模型并进行仿真分析,且与其他模型的识别结果进行对比。结果表明,相比算例中列出的几种对比模型,IGWO-LSSVM模型识别结果的正确率更高,验证了所提PQD识别方法的有效性和实用性。展开更多
There are many documented sex differences in the clinical course,symptom expression profile,and treatment response of Parkinson’s disease,creating additional challenges for patient management.Although subthalamic nuc...There are many documented sex differences in the clinical course,symptom expression profile,and treatment response of Parkinson’s disease,creating additional challenges for patient management.Although subthalamic nucleus deep brain stimulation is an established therapy for Parkinson’s disease,the effects of sex on treatment outcome are still unclear.The aim of this retrospective observational study,was to examine sex differences in motor symptoms,nonmotor symptoms,and quality of life after subthalamic nucleus deep brain stimulation.Outcome measures were evaluated at 1 and 12 months post-operation in 90 patients with Parkinson’s disease undergoing subthalamic nucleus deep brain stimulation aged 63.00±8.01 years(55 men and 35 women).Outcomes of clinical evaluations were compared between sexes via a Student’s t-test and within sex via a paired-sample t-test,and generalized linear models were established to identify factors associated with treatment efficacy and intensity for each sex.We found that subthalamic nucleus deep brain stimulation could improve motor symptoms in men but not women in the on-medication condition at 1 and 12 months post-operation.Restless legs syndrome was alleviated to a greater extent in men than in women.Women demonstrated poorer quality of life at baseline and achieved less improvement of quality of life than men after subthalamic nucleus deep brain stimulation.Furthermore,Hoehn-Yahr stage was positively correlated with the treatment response in men,while levodopa equivalent dose at 12 months post-operation was negatively correlated with motor improvement in women.In conclusion,women received less benefit from subthalamic nucleus deep brain stimulation than men in terms of motor symptoms,non-motor symptoms,and quality of life.We found sex-specific factors,i.e.,Hoehn-Yahr stage and levodopa equivalent dose,that were related to motor improvements.These findings may help to guide subthalamic nucleus deep brain stimulation patient selection,prognosis,and stimulation programming for optimal therapeutic efficacy in Parkinson’s disease.展开更多
文摘Crime cases from snatch thefts to murders, are becoming increasingly common in Malaysia according to the database of the Royal Malaysian Police （RMP）, the current overall Crime Index in Malaysia was 147,062 for 2013 compared with 65,237 in 1977. The database also revealed that the number of property crimes reported in this country has always exceeded the number of violent crimes. Although in 2013, crimes related to property are higher （117,687） than violent crime （29,375）, the gradual increase in the latter does worry Malaysians. Likewise, Malaysian Government had implemented a ＂safe community＂ concept, inspired by the Malaysian Crime Prevention Foundation （MCPF）, a non-government organization, as they were concerned that the threat of violent crime and non-violent crime would eventually reduce the quality of life for many individuals. The concept is very important to the public as it is perceived as improved safety for the public with less crime. This study analyzes the public safety through their perceptions on the effectiveness of the policeman and suggesting few prevention actions against crime. The data were collected using a self-administered survey questionnaire. Specifically, this study focuses on the more developed states in this country. From the cross tabulation analysis, the majority of respondents agreed that the police are effective in controlling crime. Approximately, 72.1% of respondents felt that the police are efficient in controlling crime.
文摘Background: Deep brain stimulation (DBS) is an established treatment for patients with advanced Parkinson’s disease (PD). Reports show continued patient satisfaction after surgery despite not maintaining clinical improvement as measured by evolution scales. Objectives: The present study sought to explore expectations and level of satisfaction in patients after DBS surgery with a semi-structured questionnaire and subsequent correlation with functional scales, Quality of Life (QoL), and motor and non-motor symptoms. Methods: We performed descriptive statistics to represent demographic data, Wilcoxon rank tests to determine significant differences, and Spearman correlation between the applied scales. Results: We evaluated 20 patients with a history of DBS surgery. 45% were female, with a mean age of 55.7 ± 14.15 years, a mean disease duration of 13.42 ± 8.3 years, and a mean time after surgery of 3.18 ± 1.86 years. Patients reported surgery meeting expectations in 85.5% and continued satisfaction in 92%. These two variables showed a significant correlation. Conclusions: This sample of patients remained satisfied after DBS surgery, although we found no differences in motor and non-motor clinimetric scales. Further studies are needed to confirm the importance of assessing quality of life in patients with DBS.
文摘为了提高电能质量扰动(power quality disturbance,PQD)识别结果的准确性,笔者提出一种基于改进灰狼优化算法(improved grey wolf optimization,IGWO)优化最小二乘支持向量机(least squares support vector machine,LSSVM)的PQD识别方法。通过采用收敛因数指数调整、自适应位移和权重动态修订等措施对灰狼优化算法进行改进,得到IGWO算法;以PQD信号的9个特征量为支持向量、7种PQD类型为输出量,利用IGWO算法寻找LSSVM的最优参数,建立基于IGWO-LSSVM的PQD识别模型并进行仿真分析,且与其他模型的识别结果进行对比。结果表明,相比算例中列出的几种对比模型,IGWO-LSSVM模型识别结果的正确率更高,验证了所提PQD识别方法的有效性和实用性。
基金support by the National Nature Science Foundation of China,Nos.81830033,61761166004(both to JGZ)。
文摘There are many documented sex differences in the clinical course,symptom expression profile,and treatment response of Parkinson’s disease,creating additional challenges for patient management.Although subthalamic nucleus deep brain stimulation is an established therapy for Parkinson’s disease,the effects of sex on treatment outcome are still unclear.The aim of this retrospective observational study,was to examine sex differences in motor symptoms,nonmotor symptoms,and quality of life after subthalamic nucleus deep brain stimulation.Outcome measures were evaluated at 1 and 12 months post-operation in 90 patients with Parkinson’s disease undergoing subthalamic nucleus deep brain stimulation aged 63.00±8.01 years(55 men and 35 women).Outcomes of clinical evaluations were compared between sexes via a Student’s t-test and within sex via a paired-sample t-test,and generalized linear models were established to identify factors associated with treatment efficacy and intensity for each sex.We found that subthalamic nucleus deep brain stimulation could improve motor symptoms in men but not women in the on-medication condition at 1 and 12 months post-operation.Restless legs syndrome was alleviated to a greater extent in men than in women.Women demonstrated poorer quality of life at baseline and achieved less improvement of quality of life than men after subthalamic nucleus deep brain stimulation.Furthermore,Hoehn-Yahr stage was positively correlated with the treatment response in men,while levodopa equivalent dose at 12 months post-operation was negatively correlated with motor improvement in women.In conclusion,women received less benefit from subthalamic nucleus deep brain stimulation than men in terms of motor symptoms,non-motor symptoms,and quality of life.We found sex-specific factors,i.e.,Hoehn-Yahr stage and levodopa equivalent dose,that were related to motor improvements.These findings may help to guide subthalamic nucleus deep brain stimulation patient selection,prognosis,and stimulation programming for optimal therapeutic efficacy in Parkinson’s disease.
