A multi-layered composite scaffolds consisting of poly （ L- ne） （ P （LLA-CL） ）, collagen （COL） and chitosan （CS） were fabricated by a bi-directional electrospinnlng method. Synthetic P （LLA-CL） was used as...A multi-layered composite scaffolds consisting of poly （ L- ne） （ P （LLA-CL） ）, collagen （COL） and chitosan （CS） were fabricated by a bi-directional electrospinnlng method. Synthetic P （LLA-CL） was used as the middle layer to enhance the strength, while natural COL/CS blending （9： 1, v/v） was used as the bioactive surfaces （inner and outer layers ） to improve the biocompatibility. Each three transitional layers were set between inner/outer layer and middle layer for delamination resistance. Scanning electron microscopy （SEM） was used to observe the fiber morphology. The Fourier transform infrared attenuated total reflectance spectroscopy （FTIR-ATR） spectra, X- ray diffraction （XRD） and thermogravimetry （TG） tests were used to analyze the physical properties of the scaffolds. The results showed that the modified clectrospinning method bad no negative effect on the components, crystal structure and thermostability of the scaffolds, but could effectively combine the mechanical property of synthetic material and biocompatibility of natural materials. Such method could be applied to the fabrication of composite scaffolds for vascular, skin. and nerve tissue engineering.展开更多
研究用壳聚糖、聚铝和助剂 A 复合制备出一种成本低、絮凝效果好、出水铝离子含量少的新型自来水处理絮凝剂,并确定其最佳配比为:v(0.1%壳聚糖):v(2%聚合氯化铝):v(0.1%助剂 A)=1:6:5。此絮凝剂与传统聚铝类絮凝剂相比,其出水浊度和铝...研究用壳聚糖、聚铝和助剂 A 复合制备出一种成本低、絮凝效果好、出水铝离子含量少的新型自来水处理絮凝剂,并确定其最佳配比为:v(0.1%壳聚糖):v(2%聚合氯化铝):v(0.1%助剂 A)=1:6:5。此絮凝剂与传统聚铝类絮凝剂相比,其出水浊度和铝离子质量分数分别下降了2.97%和10.7%,并且药剂成本下降6.25%,有明显的经济和环境效益。展开更多
基金"111 Project" Biomedical Textile Materials Science and Technology,China，National Natural Science Foundations of China，Science and Technology Commission of Shanghai Municipality,China，Ph.D.Programs Foundation of Ministry of Education of China
文摘A multi-layered composite scaffolds consisting of poly （ L- ne） （ P （LLA-CL） ）, collagen （COL） and chitosan （CS） were fabricated by a bi-directional electrospinnlng method. Synthetic P （LLA-CL） was used as the middle layer to enhance the strength, while natural COL/CS blending （9： 1, v/v） was used as the bioactive surfaces （inner and outer layers ） to improve the biocompatibility. Each three transitional layers were set between inner/outer layer and middle layer for delamination resistance. Scanning electron microscopy （SEM） was used to observe the fiber morphology. The Fourier transform infrared attenuated total reflectance spectroscopy （FTIR-ATR） spectra, X- ray diffraction （XRD） and thermogravimetry （TG） tests were used to analyze the physical properties of the scaffolds. The results showed that the modified clectrospinning method bad no negative effect on the components, crystal structure and thermostability of the scaffolds, but could effectively combine the mechanical property of synthetic material and biocompatibility of natural materials. Such method could be applied to the fabrication of composite scaffolds for vascular, skin. and nerve tissue engineering.
文摘研究用壳聚糖、聚铝和助剂 A 复合制备出一种成本低、絮凝效果好、出水铝离子含量少的新型自来水处理絮凝剂,并确定其最佳配比为:v(0.1%壳聚糖):v(2%聚合氯化铝):v(0.1%助剂 A)=1:6:5。此絮凝剂与传统聚铝类絮凝剂相比,其出水浊度和铝离子质量分数分别下降了2.97%和10.7%,并且药剂成本下降6.25%,有明显的经济和环境效益。
