Modulating metal-organic framework’s(MOF)crystallinity and size using a polymer,in conjunction with a high surface area of layered double hydroxide,yields an effective strategy for concurrently enhancing the electroc...Modulating metal-organic framework’s(MOF)crystallinity and size using a polymer,in conjunction with a high surface area of layered double hydroxide,yields an effective strategy for concurrently enhancing the electrochemical and photocatalytic performance.In this study,we present the development of an optimized nanocomposite,denoted as 0.5PVP/ZIF-67,developed on AZ31 magnesium alloy,serving as an efficient and durable multifunctional coating.This novel strategy aims to enhance the overall performance of the porous coating through the integration of microarc oxidation(MAO),ZnFe LDH backbone,and ZIF-67 formation facilitated by the addition of polyvinylpyrrolidone(PVP),resulting in a three-dimensional,highly efficient,and multifunctional material.The incorporation of 0.5 g of PVP proved to be effective in the size modulation of ZIF-67,which formed a corrosion-resistant top layer,improving the total polarization resistance(R_(p)=8.20×10^(8)).The dual functionality exhibited by this hybrid architecture positions it as a promising candidate for mitigating environmental pollution,degrading 97.93%of Rhodamine B dye in 45 min.Moreover,the sample displayed exceptional degradation efficiency(96.17%)after 5 cycles.This study illuminates the potential of nanocomposites as electrochemically stable and photocatalytically active materials,laying the foundation for the advancements of next-generation multifunctional frameworks.展开更多
Among the different bioprinting techniques,the drop-on-demand(DOD)jetting-based bioprinting approach facilitates contactless deposition of pico/nanoliter droplets ofmaterials and cells for optimal cell–matrix and cel...Among the different bioprinting techniques,the drop-on-demand(DOD)jetting-based bioprinting approach facilitates contactless deposition of pico/nanoliter droplets ofmaterials and cells for optimal cell–matrix and cell–cell interactions.Although bioinks play a critical role in the bioprinting process,there is a poor understanding of the influence of bioink properties on printing performance(such as filament elongation,formation of satellite droplets,and droplet splashing)and cell health(cell viability and proliferation)during the DOD jetting-based bioprinting process.An inert polyvinylpyrrolidone(PVP360,molecular weight=360 kDa)polymerwas used in this study to manipulate the physical properties of the bioinks and investigate the influence of bioink properties on printing performance and cell health.Our experimental results showed that a higher bioink viscoelasticity helps to stabilize droplet filaments before rupturing from the nozzle orifice.The highly stretched droplet filament resulted in the formation of highly aligned“satellite droplets,”which minimized the displacement of the satellite droplets away from the predefined positions.Next,a significant increase in the bioink viscosity facilitated droplet deposition on the wetted substrate surface in the absence of splashing and significantly improved the accuracy of the deposited main droplet.Further analysis showed that cell-laden bioinks with higher viscosity exhibited higher measured average cell viability(%),as the presence of polymer within the printed droplets provides an additional cushioning effect(higher energy dissipation)for the encapsulated cells during droplet impact on the substrate surface,improves the measured average cell viability even at higher droplet impact velocity and retains the proliferation capability of the printed cells.Understanding the influence of bioink properties(e.g.,bioink viscoelasticity and viscosity)on printing performance and cell proliferation is important for the formulation of new bioinks,and we have demonstrated precise DOD deposition of living cells and fabrication of tunable cell spheroids(nL–μL range)using multiple types of cells in a facile manner.展开更多
In this paper, ultrafine nitrogen-doped TiO2 photocatalyst with enhanced photocatalytic water-splitting properties was successfully fabricated via a solvothermal method. Herein, polyvinylpyrrolidone（PVP） was used as...In this paper, ultrafine nitrogen-doped TiO2 photocatalyst with enhanced photocatalytic water-splitting properties was successfully fabricated via a solvothermal method. Herein, polyvinylpyrrolidone（PVP） was used as both nitrogen source and stabilizer. The enhancement in water-splitting process can be attributed to the doping of element nitrogen, which could supply an intermediate energy level and promote the separation of photo-excited holes and electrons. Moreover, this paper provides a new application of high-molecular polymer to synthesize solar-driven water-splitting photocatalysts.展开更多
经皮椎体成形术(PVP)是治疗骨质疏松性脊柱骨折的常用方法,主要穿刺方式有两种,一种是单侧经椎弓根入路或者椎弓根外侧入路穿刺,另一种为双侧经椎弓根入路穿刺。本研究旨在探讨这两种穿刺方式在治疗骨质疏松性脊柱骨折中的效能差异,包...经皮椎体成形术(PVP)是治疗骨质疏松性脊柱骨折的常用方法,主要穿刺方式有两种,一种是单侧经椎弓根入路或者椎弓根外侧入路穿刺,另一种为双侧经椎弓根入路穿刺。本研究旨在探讨这两种穿刺方式在治疗骨质疏松性脊柱骨折中的效能差异,包括手术相关指标、治疗效果、并发症等方面,以便为临床抉择提供依据。通过对相关文献的综合分析,发现单侧穿刺具有手术时间短、骨水泥用量少等优点,双侧穿刺在骨水泥弥散和疼痛缓解方面可能更具优势。术者可根据个人喜好以及患者的具体情况选择合适的穿刺方式。Percutaneous vertebroplasty (PVP) is a commonly used method for treating osteoporotic spinal fractures. There are two main puncture methods, one is unilateral transpedicular or lateral approach, and the other is bilateral transpedicular approach. This study aims to explore the difference in efficacy between these two puncture methods in the treatment of osteoporotic spinal fractures, including surgical indicators, treatment effects, complications, etc., in order to provide a basis for clinical decision-making. Through comprehensive analysis of relevant literature, it was found that unilateral puncture has the advantages of short operation time and less bone cement usage, and bilateral puncture may have more advantages in bone cement diffusion and pain relief. The surgeon can choose the appropriate puncture method according to personal preferences and the specific situation of the patient.展开更多
基金supported by the National Research Foundation of Korea(NRF)funded by the Korean government(MSIT)(No.2022R1A2C1006743).
文摘Modulating metal-organic framework’s(MOF)crystallinity and size using a polymer,in conjunction with a high surface area of layered double hydroxide,yields an effective strategy for concurrently enhancing the electrochemical and photocatalytic performance.In this study,we present the development of an optimized nanocomposite,denoted as 0.5PVP/ZIF-67,developed on AZ31 magnesium alloy,serving as an efficient and durable multifunctional coating.This novel strategy aims to enhance the overall performance of the porous coating through the integration of microarc oxidation(MAO),ZnFe LDH backbone,and ZIF-67 formation facilitated by the addition of polyvinylpyrrolidone(PVP),resulting in a three-dimensional,highly efficient,and multifunctional material.The incorporation of 0.5 g of PVP proved to be effective in the size modulation of ZIF-67,which formed a corrosion-resistant top layer,improving the total polarization resistance(R_(p)=8.20×10^(8)).The dual functionality exhibited by this hybrid architecture positions it as a promising candidate for mitigating environmental pollution,degrading 97.93%of Rhodamine B dye in 45 min.Moreover,the sample displayed exceptional degradation efficiency(96.17%)after 5 cycles.This study illuminates the potential of nanocomposites as electrochemically stable and photocatalytically active materials,laying the foundation for the advancements of next-generation multifunctional frameworks.
文摘Among the different bioprinting techniques,the drop-on-demand(DOD)jetting-based bioprinting approach facilitates contactless deposition of pico/nanoliter droplets ofmaterials and cells for optimal cell–matrix and cell–cell interactions.Although bioinks play a critical role in the bioprinting process,there is a poor understanding of the influence of bioink properties on printing performance(such as filament elongation,formation of satellite droplets,and droplet splashing)and cell health(cell viability and proliferation)during the DOD jetting-based bioprinting process.An inert polyvinylpyrrolidone(PVP360,molecular weight=360 kDa)polymerwas used in this study to manipulate the physical properties of the bioinks and investigate the influence of bioink properties on printing performance and cell health.Our experimental results showed that a higher bioink viscoelasticity helps to stabilize droplet filaments before rupturing from the nozzle orifice.The highly stretched droplet filament resulted in the formation of highly aligned“satellite droplets,”which minimized the displacement of the satellite droplets away from the predefined positions.Next,a significant increase in the bioink viscosity facilitated droplet deposition on the wetted substrate surface in the absence of splashing and significantly improved the accuracy of the deposited main droplet.Further analysis showed that cell-laden bioinks with higher viscosity exhibited higher measured average cell viability(%),as the presence of polymer within the printed droplets provides an additional cushioning effect(higher energy dissipation)for the encapsulated cells during droplet impact on the substrate surface,improves the measured average cell viability even at higher droplet impact velocity and retains the proliferation capability of the printed cells.Understanding the influence of bioink properties(e.g.,bioink viscoelasticity and viscosity)on printing performance and cell proliferation is important for the formulation of new bioinks,and we have demonstrated precise DOD deposition of living cells and fabrication of tunable cell spheroids(nL–μL range)using multiple types of cells in a facile manner.
基金supported financially by the National Natural Science Foundation of China(Grant No.51272107 and Grant No.51572126)the Department of Education of Jiangsu Province(KYLX_0352)Fundamental Research Funds for the Central Universities(No.30920140132038)
文摘In this paper, ultrafine nitrogen-doped TiO2 photocatalyst with enhanced photocatalytic water-splitting properties was successfully fabricated via a solvothermal method. Herein, polyvinylpyrrolidone（PVP） was used as both nitrogen source and stabilizer. The enhancement in water-splitting process can be attributed to the doping of element nitrogen, which could supply an intermediate energy level and promote the separation of photo-excited holes and electrons. Moreover, this paper provides a new application of high-molecular polymer to synthesize solar-driven water-splitting photocatalysts.
文摘经皮椎体成形术(PVP)是治疗骨质疏松性脊柱骨折的常用方法,主要穿刺方式有两种,一种是单侧经椎弓根入路或者椎弓根外侧入路穿刺,另一种为双侧经椎弓根入路穿刺。本研究旨在探讨这两种穿刺方式在治疗骨质疏松性脊柱骨折中的效能差异,包括手术相关指标、治疗效果、并发症等方面,以便为临床抉择提供依据。通过对相关文献的综合分析,发现单侧穿刺具有手术时间短、骨水泥用量少等优点,双侧穿刺在骨水泥弥散和疼痛缓解方面可能更具优势。术者可根据个人喜好以及患者的具体情况选择合适的穿刺方式。Percutaneous vertebroplasty (PVP) is a commonly used method for treating osteoporotic spinal fractures. There are two main puncture methods, one is unilateral transpedicular or lateral approach, and the other is bilateral transpedicular approach. This study aims to explore the difference in efficacy between these two puncture methods in the treatment of osteoporotic spinal fractures, including surgical indicators, treatment effects, complications, etc., in order to provide a basis for clinical decision-making. Through comprehensive analysis of relevant literature, it was found that unilateral puncture has the advantages of short operation time and less bone cement usage, and bilateral puncture may have more advantages in bone cement diffusion and pain relief. The surgeon can choose the appropriate puncture method according to personal preferences and the specific situation of the patient.
