Bayesian partial pooling to reduce uncertainty in overcoring rock stress estimation

The state of in situ stress is a crucial parameter in subsurface engineering,especially for critical projects like nuclear waste repository.As one of the two ISRM suggested methods,the overcoring(OC)method is widely used to estimate the full stress tensors in rocks by independent regression analysis of the data from each OC test.However,such customary independent analysis of individual OC tests,known as no pooling,is liable to yield unreliable test-specific stress estimates due to various uncertainty sources involved in the OC method.To address this problem,a practical and no-cost solution is considered by incorporating into OC data analysis additional information implied within adjacent OC tests,which are usually available in OC measurement campaigns.Hence,this paper presents a Bayesian partial pooling(hierarchical)model for combined analysis of adjacent OC tests.We performed five case studies using OC test data made at a nuclear waste repository research site of Sweden.The results demonstrate that partial pooling of adjacent OC tests indeed allows borrowing of information across adjacent tests,and yields improved stress tensor estimates with reduced uncertainties simultaneously for all individual tests than they are independently analysed as no pooling,particularly for those unreliable no pooling stress estimates.A further model comparison shows that the partial pooling model also gives better predictive performance,and thus confirms that the information borrowed across adjacent OC tests is relevant and effective.

Local Torrential Rainfall Event within a Mei-Yu Season Mesoscale Convective System:Importance of Back-Building Processes

An extreme rainfall event occurred over Hangzhou,China,during the afternoon hours on 24 June 2013.This event occurred under suitable synoptic conditions and the maximum 4-h cumulative rainfall amount was over 150 mm.This rainfall event had two major rainbands.One was caused by a quasi-stationary convective line,and the other by a backbuilding convective line related to the interaction of the outflow boundary from the first rainband and an existing low-level mesoscale convergence line associated with a mei-yu frontal system.The rainfall event lasted 4 h,while the back-building process occurred in 2 h when the extreme rainfall center formed.So far,few studies have examined the back-building processes in the mei-yu season that are caused by the interaction of a mesoscale convergence line and a convective cold pool.The two rainbands are successfully reproduced by the Weather Research and Forecasting(WRF)model with fourlevel,two-way interactive nesting.In the model,new cells repeatedly occur at the west side of older cells,and the backbuilding process occurs in an environment with large CAPE,a low LFC,and plenty of water vapor.Outflows from older cells enhance the low-level convergence that forces new cells.High precipitation efficiency of the back-building training cells leads to accumulated precipitation of over 150 mm.Sensitivity experiments without evaporation of rainwater show that the convective cold pool plays an important role in the organization of the back-building process in the current extreme precipitation case.

U-Net Based Dual-Pooling Segmentation of Bone Metastases in Thoracic SPECT Bone Scintigrams

In order to enhance the performance of the CNN-based segmentation models for bone metastases, this study proposes a segmentation method that integrates dual-pooling, DAC, and RMP modules. The network consists of distinct feature encoding and decoding stages, with dual-pooling modules employed in encoding stages to maintain the background information needed for bone scintigrams diagnosis. Both the DAC and RMP modules are utilized in the bottleneck layer to address the multi-scale problem of metastatic lesions. Experimental evaluations on 306 clinical SPECT data have demonstrated that the proposed method showcases a substantial improvement in both DSC and Recall scores by 3.28% and 6.55% compared the baseline. Exhaustive case studies illustrate the superiority of the methodology.

A Decision-Support System for the Car Pooling Problem

The continuous increase of human mobility combined with a relevant use of private vehicles contributes to increase the ill effects of vehicle externalities on the environment, e.g. high levels of air pollution, toxic emissions, noise pollution, and on the quality of life, e.g. parking problem, traffic congestion, and increase in the number of crashes and accidents. Transport demand management plays a very critical role in achieving greenhouse gas emission reduction targets. This study demonstrates that car pooling (CP) is an effective strategy to reduce transport volumes, transportation costs and related hill externalities in agreement with EU programs of emissions reduction targets. This paper presents an original approach to solve the CP problem. It is based on hierarchical clustering models, which have been adopted by an original decision support system (DSS). The DSS helps mobility managers to generate the pools and to design feasible paths for shared vehicles. A significant case studies and obtained results by the application of the proposed models are illustrated. They demonstrate the effectiveness of the approach and the supporting decisions tool.

A Smart Heart Disease Diagnostic System Using Deep Vanilla LSTM

Effective smart healthcare frameworks contain novel and emerging solutions for remote disease diagnostics,which aid in the prevention of several diseases including heart-related abnormalities.In this context,regular monitoring of cardiac patients through smart healthcare systems based on Electrocardiogram(ECG)signals has the potential to save many lives.In existing studies,several heart disease diagnostic systems are proposed by employing different state-of-the-art methods,however,improving such methods is always an intriguing area of research.Hence,in this research,a smart healthcare system is proposed for the diagnosis of heart disease using ECG signals.The proposed framework extracts both linear and time-series information on the ECG signals and fuses them into a single framework concurrently.The linear characteristics of ECG signals are extracted by convolution layers followed by Gaussian Error Linear Units(GeLu)and time series characteristics of ECG beats are extracted by Vanilla Long Short-Term Memory Networks(LSTM).Following on,the feature reduction of linear information is done with the help of ID Generalized Gated Pooling(GGP).In addition,data misbalancing issues are also addressed with the help of the Synthetic Minority Oversampling Technique(SMOTE).The performance assessment of the proposed model is done over the two publicly available datasets named MIT-BIH arrhythmia database(MITDB)and PTB Diagnostic ECG database(PTBDB).The proposed framework achieves an average accuracy performance of 99.14%along with a 95%recall value.

Climate Change Impacts on Agroecosystems in China:Processes,Mechanisms and Prospects

Building a more resilient response system to climate change for sustainable development and reducing uncertainty in China’s food markets,requires access to historical research gaps and mapping future research progress for decision making.However,the lack of quantitative and objective analyses to ensure the stability and development of agroecosystems increases the complexity of agro-climatic mechanisms,which leads to uncertainty and undesirable consequences.In this paper,we review the characteristics of climate change in China(1951–2020),reveal the mechanisms of agroecosystem structure in response to climate,and identify challenges and opportunities for future efforts in the context of research progress.The aim is to improve the scientific validity and relevance of future research by clarifying agro-climatic response mechanisms.The results show that surface temperature,precipitation,and frequency of extreme weather events have increased to varying degrees in major agricultural regions of China in 1951–2020.And they have strong geographic variation,which has resulted in droughts in the north and floods in the south.Moreover,climate change has complicated the mechanisms of soil moisture,Net Primary Productivity(NPP),soil carbon pool,and crop pest structure in agroecosystems.This lends to a reduction in soil water holding capacity,NPP,soil carbon content,and the number of natural enemies of diseases and insects,which in turn affects crop yields.However,human interventions can mitigate the deterioration of these factors.We have also realized that the methodology and theory of historical research poses a great challenge to future agroecosystem.Historical and projected climate trends identified current gaps in interdisciplinary integration and multidisciplinary research required to manage diverse spatio-temporal climate change impacts on agroecosystems.Future efforts should highlight integrated management and decision making,multidisciplinary big data coupling,and numerical simulations to ensure sustainable agricultural development,ecological security,and food security in China.

基于改进Faster R-CNN的热轧带钢表面缺陷检测

热轧带钢是钢铁行业的重要产品,其表面缺陷是影响产品质量的重要因素。针对传统缺陷检测算法存在的过程繁琐、精度不足和效率低下等问题,提出一种基于改进更快速区域卷积神经网络(faster region-based convolutional neural network,Faster R-CNN)的检测算法,实现对热轧带钢表面缺陷的高效、高精度检测。首先,采用特征相加的方法对底层细节特征和高层语义特征进行融合;然后,采用精准的感兴趣区域池化(precise region of interest pooling,Precise ROI Pooling)获取固定大小的特征向量,避免特征出现位置偏差;最后,利用均值偏移聚类算法对带钢数据集进行聚类,获得适用于热轧带钢表面缺陷检测的先验框尺寸。实验结果表明,所提算法在热轧带钢表面缺陷检测数据集上的平均精度均值达到了85.34%,检测速度为23.5帧/s,且鲁棒性良好,满足实际的工业检测需求。

辛空间的排列问题及具有容错能力的pooling设计的紧界

该文利用辛空间上的子空间构造了一类新的d^z析取矩阵,然后研究了如下排列问题:对于给定的整数m,r,s,v,d,q和辛空间F_q^(2v)中的一个(m,s)型子空间S,这里v+s≥m>r≥2s-1≥1,d≥2,q是一个素数的幂,作者从S中找到d个(m-1,s-1)型子空间H_1,…H_d,使包含在这些(m-1,s-1)型子空间中的(r,s-1)型子空间个数达到最大.然后利用这个排列的有关结论,给出了一类pooling设计的紧界.

基于DNA pooling技术的全基因组关联研究筛选主动脉夹层等位基因遗传位点

目的:筛选与主动脉夹层发病机制相关的遗传易感基因。方法:从主动脉夹层患者(150例)及对照组(250例)外周血白细胞提取基因组DNA,采用DNA Pooling为基础的Illumina Human660W-Quad芯片扫描,筛选与主动脉夹层发病相关的遗传易感基因。结果:(1)对照组女性数量明显多于病例组(P<0.01);年龄、吸烟、高血压、糖尿病人数无统计学差异(P>0.05)。(2)遗传变异位点SNPrs2298491(位于TBCEL基因),SNP rs6080720(位于BFSP1基因),SNP rs7653410(位于SNTN基因),SNP rs2345106(位于COLQ基因)和位于ABCA13基因上的SNPrs4024044可能与主动脉夹层的发病有关。结论:SNPsrs2298491,rs6080720,rs7653410,rs2345106和rs4024044可能是主动脉夹层发病机制相关遗传变异位点的一部分。

利用伪辛子空间构造的一类pooling设计及其纠错能力的紧界分析

利用伪辛空间上的子空间构造了一类新的dz-析取矩阵,证明了它的析取性,讨论了反映dz-析取矩阵纠错能力z值的紧界.

奇特征正交空间上可检错Pooling设计的构作

Pooling设计的数学模型是一个d-disjunct矩阵.利用奇特征正交空间中全迷向子空间构作了d-disjunct矩阵,并通过计算它的Hamming距离分析了它的检纠错能力,根据Kautz-Singleton定理对d的范围作了估算.

NFHP-RN:AMethod of Few-Shot Network Attack Detection Based on the Network Flow Holographic Picture-ResNet

Due to the rapid evolution of Advanced Persistent Threats(APTs)attacks,the emergence of new and rare attack samples,and even those never seen before,make it challenging for traditional rule-based detection methods to extract universal rules for effective detection.With the progress in techniques such as transfer learning and meta-learning,few-shot network attack detection has progressed.However,challenges in few-shot network attack detection arise from the inability of time sequence flow features to adapt to the fixed length input requirement of deep learning,difficulties in capturing rich information from original flow in the case of insufficient samples,and the challenge of high-level abstract representation.To address these challenges,a few-shot network attack detection based on NFHP(Network Flow Holographic Picture)-RN(ResNet)is proposed.Specifically,leveraging inherent properties of images such as translation invariance,rotation invariance,scale invariance,and illumination invariance,network attack traffic features and contextual relationships are intuitively represented in NFHP.In addition,an improved RN network model is employed for high-level abstract feature extraction,ensuring that the extracted high-level abstract features maintain the detailed characteristics of the original traffic behavior,regardless of changes in background traffic.Finally,a meta-learning model based on the self-attention mechanism is constructed,achieving the detection of novel APT few-shot network attacks through the empirical generalization of high-level abstract feature representations of known-class network attack behaviors.Experimental results demonstrate that the proposed method can learn high-level abstract features of network attacks across different traffic detail granularities.Comparedwith state-of-the-artmethods,it achieves favorable accuracy,precision,recall,and F1 scores for the identification of unknown-class network attacks through cross-validation onmultiple datasets.

Tackling the proton limit under industrial electrochemical CO_(2)reduction by a local proton shuttle

Industrial CO_(2)electroreduction has received tremendous attentions for resolution of the current energy and environmental crisis,but its performance is greatly limited by mass transport at high current density.In this work,an ion‐polymer‐modified gas‐diffusion electrode is used to tackle this proton limit.It is found that gas diffusion electrode‐Nafion shows an impressive performance of 75.2%Faradaic efficiency in multicarbon products at an industrial current density of 1.16 A/cm^(2).Significantly,in‐depth electrochemical characterizations combined with in situ Raman have been used to determine the full workflow of protons,and it is found that HCO_(3)^(−)acts as a proton pool near the reaction environment,and HCO_(3)^(−)and H_(3)O^(+)are local proton donors that interact with the proton shuttle−SO_(3)^(−)from Nafion.With rich proton hopping sites that decrease the activation energy,a“Grotthuss”mechanism for proton transport in the above system has been identified rather than the“Vehicle”mechanism with a higher energy barrier.Therefore,this work could be very useful in terms of the achievement of industrial CO_(2)reduction fundamentally and practically.

Evolution Mechanism of a Severe Squall Line Triggered by the Coupling of a Sea Breeze Front and a Gust Front

In the present study, a severe squall line(SL) was analyzed by using intensive observational surface data and radar monitoring products. In this process, mesoscale convergence lines, such as the sea breeze front(SBF), gust front and dry line, served as the main triggering and strengthening factors. The transition from convection triggering to the formation of the initial shape was mainly affected by the convergence line of the SBF, which combined with thermal convection to form the main parts of the SL. In the later stage, the convergence line of the gust front merged with other convergence lines to form a series of strong convective cells. The SBF had good indicative significance in terms of severe convective weather warnings. The suitable conditions of heat, water vapor and vertical wind shear on the Shandong Peninsula were beneficial to the maintenance of the SL. Before SL occurrence, tropopause folding strengthened, which consequently enhanced the baroclinic property in the middle and upper troposphere. The high sensible heat flux at the surface easily produced a positive potential vorticity anomaly in the low layer, resulting in convective instability, which was conducive to the maintenance of these processes. In the system, when precipitation particles passed through the unsaturated air layer, they underwent strong evaporation, melting or sublimation, and the cooling effect formed negative buoyancy, which accelerated the sinking of the air and promoted the sustained development of the surface gale. Together with the development of lowlevel mesocyclones, the air pressure decreased rapidly, which was conducive to gale initiation.

Mesoscale and Microphysical Characteristics of a Double Rain Belt Event in South China on May 10–13,2022

A second rain belt sometimes occurs ahead of a frontal rain belt in the warm sector over coastal South China,leading to heavy precipitation.We examined the differences in the mesoscale characteristics and microphysics of the frontal and warm sector rain belts that occurred in South China on May 10–13,2022.The southern rain belt occurred in an environment with favorable mesoscale conditions but weak large-scale forcing.In contrast,the northern rain belt was related to low-level horizontal shear and the surface-level front.The interaction between the enhanced southeasterly winds and the rainfall-induced cold pool promoted the persistent growth of convection along the southern rain belt.The convective cell propagated east over the coastal area,where there was a large temperature gradient.The bow-shaped echo in this region may be closely related to the rear-inflow jet.By contrast,the initial convection of the northern rain belt was triggered along the front and the region of low-level horizontal shear,with mesoscale interactions between the enhanced warm-moist southeasterly airflow and the cold dome associated with the earlier rain.The terrain blocked the movement of the cold pool,resulting in the stagnation of the frontal convective cell at an early stage.Subsequently,a meso-γ-scale vortex formed during the rapid movement of the convective cell,corresponding to an enhancement of precipitation.The representative raindrop spectra for the southern rain belt were characterized by a greater number and higher density of raindrops than the northern rain belt,even though both resulted in comparable hourly rainfalls.These results help us better understand the characteristics of double rain belts over South China.

奇异线性空间上的Pooling设计及其紧界(英文)

基于有限域上的奇异线性空间的两种不同形式的子空间,构造一族具有纠错能力的Pooling设计,讨论其析取性质,给出Pooling设计的紧界。

The Importance of Setting Treatment Goals for Cardiovascular Diseases

Background: Guidelines are issued by most major organizations that focus on a specific disease entity. Guidelines should be a significant help to the practicing physician who may not be up-to-date with the recent medical literature. Unfortunately, when conflicting guidelines for a specific disease are published, confusion results. Purpose: This article provides a suggested guideline outcome measure that would benefit the physician and patient. Methods: A review of 19 different guidelines for cardiovascular disease treatment is one example of the lack of specific outcomes that currently exist. The basic problem with most guidelines is that they do not state the expected end result (i.e., the benefit to the patient) if that guideline is followed. When guidelines use cardiovascular disease risk factors to dictate therapy, the end benefit is never stated so that the patient can make an appropriate choice of which (if any) guideline to follow. Results: A good example is guidelines published by the American Heart Association for reducing cardiovascular disease. These guidelines are risk factor based and only indicate that cardiovascular disease would be reduced if followed. No specific percentage in the reduction of the incidence of disease is given. In contrast, when elimination of the disease is the stated goal of the guideline, the end result is clear. To date, this goal has been stated by only one organization devoted to eliminating cardiovascular disease. Conclusion: Guidelines need to be written to provide the physician and the patient with a specific end point that is expected when the guideline is followed. Patient acceptance and compliance will be much improved if the patient knows the risk/benefit of following the guideline’s recommendations.

采用Pyrosequencing和Pooling技术对SNP位点多态性分析

目的建立基于pyrosequencing和Pooling技术进行SNP位点的法医学多态性分析技术。方法对50名无关个体样本建立一适合pyrosequencing检测的组池;采用PyroMark Assay Design 2.0软件进行SNP位点等位基因定量分析的引物设计;对组池样本PCR产物进行焦磷酸测序检测。结果检测的3个SNP位点多态性良好,其中位点rs220028与以往人群调查后频率数据无显著差异。结论采用pyrosequencing和Pooling技术对SNP位点进行多态性分析,适合于位点的初筛及大规模群体调查。该技术准确可靠,方便快捷。

Expanding the liver donor pool worldwide with hepatitis C infected livers, is it the time?

Liver transplantation(LT)provides a life-saving option for cirrhotic patients with complications and hepatocellular carcinoma.Despite the increasing number of liver transplants performed each year,the number of LT candidates on the waitlist remains unchanged due to an imbalance between donor organ supply and the demand which increases the waitlist time and mortality.Living donor liver transplant had a great role in increasing the donor pool and shortened waitlist time for LT candidates.Nevertheless,further strategies can be implemented to increase the pool of potential donors in deceased donor LT,such as reducing the rate of organ discards.Utilizing hepatitis C virus(HCV)seropositive liver grafts is one of the expanded donor organ criteria.A yearly increase of hundreds of transplants is anticipated as a result of maximizing the utilization of HCV-positive organs for HCV-negative recipients.Direct-acting antiviral therapy's efficacy has revolutionized the treatment of HCV infection and the use of HCV-seropositive donors in transplantation.The American Society of Transplantation advises against performing transplants from HCV-infected liver donors(D+)into HCV-negative recipient(R-)unless under Institutional Review Board-approved study rules and with full informed consent of the knowledge gaps associated with such transplants.Proper selection of patients to be transplanted with HCV-infected grafts and confirming their access to direct-acting antivirals if needed is im-portant.National and international consensuses are needed to regulate this process to ensure the maximum benefit and the least adverse events.

特征不为2的正交空间上的一类Pooling设计的构作

非适应性群验在DNA序列筛选等方面有许多实际应用.构作容错和纠错能力强的pooling设计是非适应性群验的中心问题之一.利用正交空间上的一类(m,2s,s)型子空间构作了一个dz-析取矩阵,并证明了当d≤q+1时,z值是最佳的.