目的采用Meta分析方法探讨中国儿童支气管哮喘控制不良的状况及影响因素,为避免儿童哮喘恶化提供循证依据。方法检索中国知网、中国生物医学文献服务系统、维普网、万方数据知识服务平台、Web of Science、Pubmed、Cochrane、Embase数...目的采用Meta分析方法探讨中国儿童支气管哮喘控制不良的状况及影响因素,为避免儿童哮喘恶化提供循证依据。方法检索中国知网、中国生物医学文献服务系统、维普网、万方数据知识服务平台、Web of Science、Pubmed、Cochrane、Embase数据库中关于中国儿童支气管哮喘控制不良情况及影响因素的病例对照研究、队列研究及横断面研究文献,检索时限从建库至2023年4月,按照纳入与排除标准由两名研究者独立筛选文献及质量评价,采用Stata17软件进行Meta分析。结果共纳入21篇文献,涉及16008例患儿,儿童支气管哮喘控制不良发生率为49%(95%CI:0.43,0.55),亚组分析显示,不同症状评估工具和地区的哮喘控制不良率差异较大,其中GINA工具70%(95%CI:0.61,0.78)和西北地区67%(95%CI:0.58,0.75)最高。反复呼吸道感染、用药依从性、哮喘家族史、过敏性鼻炎、未定期复诊、被动吸烟史以及个人过敏史是哮喘控制不良的危险因素,患儿家长学历、家庭经济水平和家长认知水平是保护因素。经过敏感性分析和Egger检验后,无明显发表偏倚。结论中国儿童哮喘控制不良发生率较高,反复呼吸道感染、用药依从性、哮喘家族史、过敏性鼻炎、未定期复诊、被动吸烟史、个人过敏史、家长学历、家庭经济水平和家长认知水平是哮喘控制不良的影响因素。展开更多
In order to provide a policy basis for improving the early development of poor rural children,this paper uses quantitative data and quantitative research methods to study the early development of children in poor rura...In order to provide a policy basis for improving the early development of poor rural children,this paper uses quantitative data and quantitative research methods to study the early development of children in poor rural areas and the impact of family environmental quality on such development. The results show that the early development of poor rural children,especially the ability of social emotion is not perfect,and the quality of family environment has a significant impact on the early development of poor rural children. Therefore,in order to improve the early development of rural children,it is necessary to attach importance to the improvement of family environment and increase the interaction with children. The government needs to establish and improve the mechanism of providing early development services,increase investment and find more efficient service model.展开更多
文摘目的采用Meta分析方法探讨中国儿童支气管哮喘控制不良的状况及影响因素,为避免儿童哮喘恶化提供循证依据。方法检索中国知网、中国生物医学文献服务系统、维普网、万方数据知识服务平台、Web of Science、Pubmed、Cochrane、Embase数据库中关于中国儿童支气管哮喘控制不良情况及影响因素的病例对照研究、队列研究及横断面研究文献,检索时限从建库至2023年4月,按照纳入与排除标准由两名研究者独立筛选文献及质量评价,采用Stata17软件进行Meta分析。结果共纳入21篇文献,涉及16008例患儿,儿童支气管哮喘控制不良发生率为49%(95%CI:0.43,0.55),亚组分析显示,不同症状评估工具和地区的哮喘控制不良率差异较大,其中GINA工具70%(95%CI:0.61,0.78)和西北地区67%(95%CI:0.58,0.75)最高。反复呼吸道感染、用药依从性、哮喘家族史、过敏性鼻炎、未定期复诊、被动吸烟史以及个人过敏史是哮喘控制不良的危险因素,患儿家长学历、家庭经济水平和家长认知水平是保护因素。经过敏感性分析和Egger检验后,无明显发表偏倚。结论中国儿童哮喘控制不良发生率较高,反复呼吸道感染、用药依从性、哮喘家族史、过敏性鼻炎、未定期复诊、被动吸烟史、个人过敏史、家长学历、家庭经济水平和家长认知水平是哮喘控制不良的影响因素。
文摘In order to provide a policy basis for improving the early development of poor rural children,this paper uses quantitative data and quantitative research methods to study the early development of children in poor rural areas and the impact of family environmental quality on such development. The results show that the early development of poor rural children,especially the ability of social emotion is not perfect,and the quality of family environment has a significant impact on the early development of poor rural children. Therefore,in order to improve the early development of rural children,it is necessary to attach importance to the improvement of family environment and increase the interaction with children. The government needs to establish and improve the mechanism of providing early development services,increase investment and find more efficient service model.
