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使用Posting Acceptor实现Form基的文件上载
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作者 王新房 邓亚玲 陈琦 《微型电脑应用》 2000年第9期8-9,17,共3页
许多 Web基应用都涉及到基于 From的文件上载。实现 From基的文件上载有许多方法可供选择 ,本文介绍利用微软的 Posting Acce Ptor实现基于 Form的文件上载过程以及如何实现匿名上载。
关键词 文件上载 WEB服务器 posting ACCEPTOR Form基
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Impact of clinical posting in psychiatry on the attitudes towards psychiatry and mental illness in undergraduate medical students 被引量:1
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作者 Rishi Desai Bharat Panchai +3 位作者 Ashok Vala Imran Jahangirali Ratnani Sneha Vadher Pushpa Khania 《General Psychiatry》 CSCD 2019年第3期130-136,共7页
Background A major public health problem around the world today is mental illness. Although there are several studies on the topic, it is rarely conducted in the context like the current study. Aims This study aims to... Background A major public health problem around the world today is mental illness. Although there are several studies on the topic, it is rarely conducted in the context like the current study. Aims This study aims to find out the attitudes of medical students towards psychiatry and mental illness as a clinical medicine major and evaluate the effects of clinical posting on their attitudes towards psychiatry and mental illness. Methods This is a longitudinal study of 6 months* duration conducted with students in their fifth semester of medical college in Western India during the academic year of 2016-2017. The participants were assessed by pro forma containing demographic details, and the questionnaires—Attitude Towards Psychiatry-30 items (ATP-30) scale and Mental Illness Clinician's Attitude (MICA) scale, which were presented to the students at the beginning and at the end of their psychiatry clinical posting. The statistical analysis was done with GraphPad, InStat V.3.06. A p value <0.05 was considered statistically significant. Results The students' attitudes towards psychiatry were neutral at the beginning of the psychiatry clinical posting, and improved significantly at the end of the posting on both scales: ATP-30 (p=0.002) and MICA (p=0.048). The students became more positive towards the subject and mental illness in general, negative attitudes also reduced but the change was not statistically significant (p=0.058). We found significant improvement in students' thinking towards being a psychiatrist in the future post-term (p=0.0002). The changes in attitude in terms of gender were equivocal, with an increase in positive attitude and reduction in negative attitude post-term in both sexes. Conclusion Psychiatry clinical posting aids in cultivating positive attitude towards psychiatry and mental illness and reduces the stigma associated with the students of this major and psychiatric patients. 展开更多
关键词 IMPACT CLINICAL posting UNDERGRADUATE medical students
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Posting of Graphical Bills: An Analytical Perception of Environmental Pollutions in Nigerian Cities
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作者 Emmanuel Bankole Oladumiye B. A. Ogunlade F. Kayode Omole 《Journal of Environmental Protection》 2017年第10期1100-1118,共19页
More than ever before, environmental preservation has been a critical issue for the survival of the world’s habitat. An attempt to explore global trends in environmental monitoring using numerous ways based on differ... More than ever before, environmental preservation has been a critical issue for the survival of the world’s habitat. An attempt to explore global trends in environmental monitoring using numerous ways based on different techniques is an exercise in the right direction. This is expedient, given the recent overwhelming growing rate of environmental pollution of advertisement graphical bills worldwide. Posting of advertisement graphical bills constitutes one of the biggest threats to man and his environment as it now appears and as we live in an age of growing sensitivity to environmental cleanliness. Pollution of the Nigerian cities through advertisement bills assumes the general term of outdoor advertising ranging from hand-printed signs, posters, painted bulletins and spectaculars. However this paper discusses the trends of posting graphic advertisement bills in Nigerian cities. Its impact on aesthetics, as well as the pollution problems associated with the urban development. The study areas are Abuja, Akure, Ibadan and Lagos. In order to ensure that each unit of the population is represented, random sampling technique was used to get the necessary information from the samples. The findings emphasize the importance of strict control and market regulations in posting of advertisement bill in built environment and eradication of pollution of the environment. 展开更多
关键词 GRAPHICAL Bills POLLUTION Environmental posting PERCEPTION
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Training medical undergraduates in the core disciplines of community medicine through community postings-an experience from India 被引量:5
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作者 Hemant Deepak Shewade Chinnakali Palanivel Kathiresan Jeyashree 《Family Medicine and Community Health》 2016年第3期45-50,共6页
Objective:Family medicine,epidemiology,health management and health promotion are the core disciplines of community medicine.In this paper,we discuss the development of a commu-nity posting program within the framewor... Objective:Family medicine,epidemiology,health management and health promotion are the core disciplines of community medicine.In this paper,we discuss the development of a commu-nity posting program within the framework of community medicine core disciplines at a primary health centre attached to a teaching hospital in Puducherry,India.Methods:This is a process documentation of our experience.Results:There were some shortcomings which revolved around the central theme that post-ings were conducted with department in the teaching hospital as the focal point,not the primary health centre(PHC).To address the shortcomings,we made some changes in the existing com-munity posting program in 2013.Student feedback aimed at Kirkpatrick level 1(satisfaction)evaluation revealed that they appreciated the benefits of having the posting with PHC as the focal point.Feedback recommended some further changes in the community posting which could be addressed through complete administrative control of the primary health centre as urban health and training center of the teaching hospital;and also through practice of core disciplines of com-munity medicine by faculty of community medicine.Conclusion:It is important to introduce the medical undergraduates to the core disciplines of community medicine early through community postings.Community postings should be con-ducted with primary health centre or urban health and training centre as the focal point. 展开更多
关键词 Family medicine community posting clinical posting community-based medical education undergraduate medical education EPIDEMIOLOGY health management health promotion
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‘I’m Sorry’ Posting
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作者 DING WENLEI 《Beijing Review》 2010年第1期44-44,共1页
A poster on a popular Chinese online community provides young Chinese netizens with a chance to look back at their past and address regrets
关键词 I’m Sorry posting
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改良Aldrete量表和DPART在全身麻醉术后复苏病人中的应用效果比较
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作者 邵振莉 吴中义 +1 位作者 王宜庭 马千里 《护理研究》 北大核心 2024年第5期897-901,共5页
目的:探讨中文版DPART量表与改良Aldrete量表对全身麻醉病人术后复苏效果的评估效果。方法:以全身麻醉术后入麻醉复苏室(PACU)接受治疗的病人为研究对象,按手术日期先后顺序分为改良Aldrete组和DPART组。改良Aldrete组105例病人采用改良... 目的:探讨中文版DPART量表与改良Aldrete量表对全身麻醉病人术后复苏效果的评估效果。方法:以全身麻醉术后入麻醉复苏室(PACU)接受治疗的病人为研究对象,按手术日期先后顺序分为改良Aldrete组和DPART组。改良Aldrete组105例病人采用改良Aldrete作为出室评估工具,DPART组109例病人采用DPART作为出室评估工具,比较两组病人PACU停留时间、出室时疼痛评分、镇静躁动得分、苏醒期躁动发生率、恶心呕吐评分和护士对于两种量表的可行性、实用性评价。结果:DPART组PACU停留时间长于改良Aldrete组(P<0.05),但出室时疼痛评分、恶心呕吐评分低于改良Aldrete组(P<0.05);两组出室时镇静躁动得分及苏醒期躁动发生率比较差异无统计学意义(P>0.05);DPART组量表的可行性评分低于改良Aldrete组(P<0.05),实用性评分高于改良Aldrete组(P<0.05)。结论:应用中文版DPART量表评估PACU病人,病人PACU停留时间较使用改良Aldrete量表评估延长,但病人出室时各项体征表现较好,更有利于保障全身麻醉术后病人安全转出PACU。 展开更多
关键词 麻醉复苏室 改良Aldrete量表 中文版Discerning Post Anesthesia Readiness for Transition Tool 全身麻醉 护理安全 并发症
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农业气象实况表的设计与自动化实现
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作者 郑文全 彭雲 何希望 《智能计算机与应用》 2024年第11期103-107,共5页
利用Excel强大的数据处理和编程功能,设计出达州市农业气象实况表。该表利用VBA进行Http远程登录、查询,完成实时气象要素的更新,并使用公式、条件格式、图表等可视化呈现农业气象指标,实现了即开即得,避免了人为失误,提高了工作效率。
关键词 VBA Http POST TOKEN 正则表达式 条件格式
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SARS-CoV2 Nsp3 protein triggers cell death and exacerbates amyloid β42-mediated neurodegeneration 被引量:1
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作者 Aditi Singh Anuradha Venkatakrishnan Chimata +4 位作者 Prajakta Deshpande Soumya Bajpai Anjali Sangeeth Mrigendra Rajput Amit Singh 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第6期1385-1392,共8页
Infection caused by the severe acute respiratory syndrome coronavirus 2(SARS-CoV2)virus,responsible for the coronavirus disease 2019(COVID-19)pandemic,induces symptoms including increased inflammatory response,severe ... Infection caused by the severe acute respiratory syndrome coronavirus 2(SARS-CoV2)virus,responsible for the coronavirus disease 2019(COVID-19)pandemic,induces symptoms including increased inflammatory response,severe acute respiratory syndrome(SARS),cognitive dysfunction like brain fog,and cardiovascular defects.Long-term effects of SARS-CoV2 COVID-19 syndrome referred to as post-COVID-19 syndrome on age-related progressive neurodegenerative disorders such as Alzheimer's disease remain understudied.Using the targeted misexpression of individual SARS-CoV2 proteins in the retinal neurons of the Drosophila melanogaster eye,we found that misexpression of nonstructural protein 3(Nsp3),a papain-like protease,ablates the eye and generates dark necrotic spots.Targeted misexpression of Nsp3 in the eye triggers reactive oxygen species production and leads to apoptosis as shown by cell death reporters,terminal deoxynucleotidyl transferase(TdT)dUTP Nick-end labeling(TUNEL)assay,and dihydroethidium staining.Furthermore,Nsp3 misexpression activates both apoptosis and autophagy mechanism(s)to regulate tissue homeostasis.Transient expression of SARS-CoV2 Nsp3 in murine neuroblastoma,Neuro-2a cells,significantly reduced the metabolic activity of these cells and triggers cell death.Misexpression of SARS-CoV2 Nsp3 in an Alzheimer's disease transgenic fly eye model(glass multiple repeats[GMR]>amyloidβ42)further enhances the neurodegenerative rough eye phenotype due to increased cell death.These findings suggest that SARS-CoV2 utilizes Nsp3 protein to potentiate cell death response in a neurodegenerative disease background that has high pre-existing levels of neuroinflammation and cell death. 展开更多
关键词 Alzheimer's disease apoptosis autophagy COVID-19 DROSOPHILA NECROSIS Neuro-2a cells NEURODEGENERATION post COVID-19 syndrome SARS-CoV2
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Spatiotemporal Evolution of Urban Heat Islands and Optimization of Spatial Network Construction in the Central Urban Area of Fuzhou City, China
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作者 ZHAO Qiuyue YU Kunyong +3 位作者 GENG Jianwei LIN Jiqing AI Jingwen LIU Jian 《Chinese Geographical Science》 SCIE CSCD 2024年第5期917-930,共14页
Although accelerated urbanization has led to economic prosperity,it has also resulted in urban heat island effects.Therefore,identifying methods of using limited urban spaces to alleviate heat islands has become an ur... Although accelerated urbanization has led to economic prosperity,it has also resulted in urban heat island effects.Therefore,identifying methods of using limited urban spaces to alleviate heat islands has become an urgent issue.In this study,we assessed the spatiotemporal evolution of urban heat islands within the central urban area of Fuzhou City,China from 2010 to 2019.This assessment was based on a morphological spatial pattern analysis(MSPA)model and an urban thermal environment spatial network constructed us-ing the minimum cumulative resistance(MCR)model.Optimization measures for the spatial network were proposed to provide a theor-etical basis for alleviating urban heat islands.The results show that the heat island area within the study area gradually increased while that of urban cold island area gradually decreased.The core area was the largest of the urban heat island patch landscape elements with a significant impact on other landscape elements,and represented an important factor underlying urban heat island network stability.The thermal environment network revealed a total of 197 thermal environment corridors and 93 heat island sources.These locations were then optimized according to the current land use,which maximized the potential of 1599.83 ha.Optimization based on current land use led to an increase in climate resilience,with effective measures showing reduction in thermal environment spatial network structure and function,contributing to the mitigation of urban heat island.These findings support the use of current land use patterns during urban heat island mitigation measure planning,thus providing an important reference basis for alleviating urban heat island effects. 展开更多
关键词 urban heat island spatiotemporal analysis circuit theory post optimization evaluation climate mitigation Fuzhou City China
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Compressive properties of glue-laminated timber circular post modified by basalt fiber reinforced polymer
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作者 WEI Peixing GUO Wenzhen +2 位作者 ZHAO Mingjing GUO Zhensheng WANG Jianhe 《林业工程学报》 CSCD 北大核心 2024年第5期67-74,共8页
Glued timber structure is one of the main forms of modern wood architecture,which has gradually developed towards mid-and high-rise buildings.Glue-laminated timber(GLT)is comprised of several laminates of parallel-to-... Glued timber structure is one of the main forms of modern wood architecture,which has gradually developed towards mid-and high-rise buildings.Glue-laminated timber(GLT)is comprised of several laminates of parallel-to-grain dimension lumber that are bonded together with durable,moisture resistant structural adhesives.GLT can be used in horizontal applications as a beam and in vertical applications as a post.So,its compressive performance has a significant impact on structural safety.Fiber reinforced polymers(FRPs)were commonly used to improve the bearing capacity of GLT components,and the structural and process parameters largely determined the reinforcement effect.This study was aimed at investigating the influence of structural and process parameters on the axial compression performance of GLT components.Three wrapping methods(middle-part,end-part and full wrapping)and three lengths(0.6,0.8,and 1.0 m)of wood post specimens were designed in this work and the axial compression performance and ductility of GLT post specimens modified by basalt fiber reinforced polymer(BFRP)were studied.The results showed that the effect of different BFRP wrapping methods on the compressive strength and elastic modulus of laminated wood was not statistically significant(P>0.05).The compressive bearing capacity of unreinforced GLT posts decreased with the increase of aspect ratio.The GLT posts with middle-part and end-part wrapping still followed this pattern,while the compressive bearing capacity of GLT posts with full wrapping showed a pattern of first decreasing and then increasing.For GLT with low aspect ratios(4.0 or 5.3),there was no correlation between the wrapping method and the compressive bearing capacity,while the compressive bearing capacity of GLT with a high aspect ratio(6.7)for middle-part,end-part and full wrapping increased by 3.5%,7.5%and 9.7%,respectively.Compared to the unreinforced group,the ultimate axial compressive strength and modulus of elasticity(MOE)of the 6-E series specimens reinforced at both ends decreased by 2.58%and 6.70%,respectively.The ultimate axial compressive strength of the 8-E specimens reinforced at both ends increased by 8.62%and the MOE decreased by 1.91%.The compressive strength of the 10-E specimens reinforced at both ends increased by 7.51%and the MOE increased by 8.14%.The failure modes of GLT with different aspects were consistent under the same BFRP wrapping,while the failure modes of GLT with the same aspect ratio were different for different BFRP wrapping methods.The ductility performance of GLT with different aspects ratio was improved by the BFRP wrapping. 展开更多
关键词 basalt fiber reinforced polymer(BFRP) GLT circular post bearing performance
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Intraocular pressure and gonioscopic findings in primary angle-closure disease in India—a big data study
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作者 Srikantaiah Ramyashri Anthony Vipin Das Sirisha Senthil 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2024年第8期1495-1500,共6页
AIM:To describe the gonioscopic profile and intraocular pressure(IOP)in primary angle-closure(PAC)disease in patients presenting to a tertiary eye care network in India.METHODS:A cross-sectional hospital-based study t... AIM:To describe the gonioscopic profile and intraocular pressure(IOP)in primary angle-closure(PAC)disease in patients presenting to a tertiary eye care network in India.METHODS:A cross-sectional hospital-based study that included 31484 new patients presenting between 2011 and 2021.Patients with a clinical diagnosis of PAC/suspect/glaucoma were included.The data was collected from an electronic medical record system.RESULTS:PAC glaucoma(PACG)(47.55%)was the most common diagnosis followed by PAC(39.49%)and PAC suspect(PACS;12.96%).Female preponderance(54.6%)was noted with higher mean age at presentation among males(P<0.0001).PACS and PAC showed the highest prevalence in 6th decade but PACG was higher at 7th decade.The probability of angle opening was 95.93%,90.32%and 63.36%in PACS,PAC and PACG eyes respectively post peripheral iridotomy(PI).Plateau iris syndrome(PIS)was noted in 252 eyes and all showed post dilated rise of IOP.A post dilated IOP rise was also noted with 8.86%,33.95%and 57.19%eyes with PACS,PAC and PACG respectively with IOP rise between 6-8 mm Hg across the disease spectrum.CONCLUSION:The superior quadrant is the narrowest angle and difficult to open with indentation and post PI.The probability of angle opening is less in PIS especially the complete variety along with post dilated IOP rise.The post dilated IOP rise in angle closure eyes warrants a careful dilatation,especially with PIS. 展开更多
关键词 angle closure disease peripheral iridectomy GONIOSCOPY post dilated intraocular pressure rise plateau iris syndrome
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Spectrum of delayed post-hypoxic leukoencephalopathy syndrome:A systematic review
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作者 Bahadar S Srichawla Maria A Garcia-Dominguez 《World Journal of Clinical Cases》 SCIE 2024年第29期6285-6301,共17页
BACKGROUND Delayed post hypoxic leukoencephalopathy syndrome(DPHLS),also known as Grinker’s myelinopathy,is a rare but significant neurological condition that manifests days to weeks after a hypoxic event.Characteriz... BACKGROUND Delayed post hypoxic leukoencephalopathy syndrome(DPHLS),also known as Grinker’s myelinopathy,is a rare but significant neurological condition that manifests days to weeks after a hypoxic event.Characterized by delayed onset of neurological and cognitive deficits,DPHLS presents substantial diagnostic and therapeutic challenges.AIM To consolidate current knowledge on pathophysiology,clinical features,diagnostic approaches,and management strategies for DPHLS,providing a comprehensive overview and highlighting gaps for future research.METHODS Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyzes guidelines,we systematically searched PubMed,ScienceDirect and Hinari databases using terms related to delayed post-hypoxic leukoencephalopathy.Inclusion criteria were original research articles,case reports,and case series involving human subjects with detailed clinical,neuroimaging,or pathological data on DPHLS.Data were extracted on study characteristics,participant demographics,clinical features,neuroimaging findings,pathological findings,treatment,and outcomes.The quality assessment was performed using the Joanna Briggs Institute critical appraisal checklist.RESULTS A total of 73 cases were reviewed.Common comorbidities included schizoaffective disorder,bipolar disorder,hypertension,and substance use disorder.The primary causes of hypoxia were benzodiazepine overdose,opioid overdose,polysubstance overdose,and carbon monoxide(CO)poisoning.Symptoms frequently include decreased level of consciousness,psychomotor agitation,cognitive decline,parkinsonism,and encephalopathy.Neuroimaging commonly revealed diffuse T2 hyperintensities in cerebral white matter,sometimes involving the basal ganglia and the globus pallidus.Magnetic resonance spectroscopy often showed decreased N-acetylaspartate,elevated choline,choline-to-creatinine ratio,and normal or elevated lactate.Treatment is often supportive,including amantadine,an antioxidant cocktail,and steroids.Hyperbaric oxygen therapy may be beneficial in those with CO poisoning.Parkinsonism was often treated with levodopa.Most of the patients had substantial recovery over the course of months and many cases had some residual neurocognitive deficits.CONCLUSION DPHLS remains a complex and multifaceted condition with various etiologies and clinical manifestations.Early recognition and appropriate management are crucial to improving patient outcomes.Future research should focus on standardizing diagnostic criteria,using advanced imaging techniques,and exploring therapeutic interventions to improve understanding and treatment of DPHLS.Conducting prospective cohort studies and developing biomarkers for early diagnosis and monitoring will be essential to advance patient care. 展开更多
关键词 Delayed post hypoxic leukoencephalopathy syndrome Anoxic encephalopathy Delayed post hypoxic leukoencephalopathy Hypoxic-ischemic brain injury Grinker's myelinopathy Toxic leukoencephalopathy Toxic leukoencephalopathy Delayed postanoxic encephalopathy Carbon monoxide poisoning
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Post competency training in standardized training of resident physicians and integrated postgraduates
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作者 Yan Zeng Jian Yang Jun-Wen Zhang 《World Journal of Clinical Cases》 SCIE 2024年第29期6250-6254,共5页
We focus on the importance and necessity of post-competency-based training in medical education alongside its current challenges and opportunities.Integrating post competency training into standardized educational fra... We focus on the importance and necessity of post-competency-based training in medical education alongside its current challenges and opportunities.Integrating post competency training into standardized educational frameworks is increasingly recognized as a critical component of preparing residents and postgraduates for real-world clinical practice.Post competency training represents a commitment to excellence in medical education,striving to produce competent,skilled practitioners to meet the challenges of modern healthcare. 展开更多
关键词 Post competency Standardized training RESIDENT POSTGRADUATE Competencybased medical education
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Non-steroidal anti-inflammatory drugs in postoperative hand fracture management:Do they positively or negatively impact recovery?
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作者 Andrew Gorgy Jacqueline Dalfen +1 位作者 Natasha Barone Johnny Ionut Efanov 《World Journal of Clinical Cases》 SCIE 2024年第21期4856-4858,共3页
This editorial explores the impact of non-steroidal anti-inflammatory drugs(NSAIDs)on postoperative recovery in hand fracture patients,amidst shifting pain management strategies away from opioids due to their adverse ... This editorial explores the impact of non-steroidal anti-inflammatory drugs(NSAIDs)on postoperative recovery in hand fracture patients,amidst shifting pain management strategies away from opioids due to their adverse effects.With hand fractures being significantly common and postoperative pain management crucial for recovery,the potential of NSAIDs offers a non-addictive pain control alternative.However,the controversy over NSAIDs'effects on bone healing—stemming from their Cyclooxygenase-2 inhibition and associated risks of fracture non-union or delayed union—necessitates further investigation.Despite a comprehensive literature search,the study finds a lack of specific research on NSAIDs in postoperative hand fracture management,highlighting an urgent need for future studies to balance their benefits against possible risks. 展开更多
关键词 Hand fracture Post operative management Non-steroidal anti-inflammatory drugs NON-UNION Bone healing Cyclooxygenase-2 inhibitors Opioid alternatives
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Research on Optimal Design of Campus Space Based on POE Concept: A Case Study of Anhui Xinhua College
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作者 XU Huaxue ZHAO Zhiyan +1 位作者 ZHU Rong NIU Song 《Journal of Landscape Research》 2024年第2期15-17,24,共4页
Through the analysis of the overall landscape,revetments and roads and plant landscape,10 evaluation factors were determined.The comprehensive evaluation model for the campus space of Anhui Xinhua University was const... Through the analysis of the overall landscape,revetments and roads and plant landscape,10 evaluation factors were determined.The comprehensive evaluation model for the campus space of Anhui Xinhua University was constructed by analytic hierarchy process(AHP).The results showed that revetment safety,road convenience,plant disease resistance and campus activity space were important factors affecting the spatial form planning of campus.Through the comparative analysis of the collected data,optimization suggestions were put forward to provide a basis for the establishment of“people-oriented”campus open space system. 展开更多
关键词 Post occupancy evaluation Analytic hierarchy process method CAMPUS Space optimization
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Feasibility of Integrating Leprosy Post-Exposure Prophylaxis with Single-Dose Rifampicin (LPEP) into Routine Leprosy Control Program in Bukedi and Teso Regions in Uganda
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作者 Rose Kengonzi Turyahabwe Stavia +9 位作者 Lisa Gerwing-Adima Nyote Ronald Kamara Vincent Consolata Mbambara Yusuf Wanyama Buyinza Godfrey Tinyo Daniel Mulwani Elisa Namuyode Damali Aloket Francis 《Advances in Infectious Diseases》 CAS 2024年第3期563-580,共18页
Background: World Health Organization recommends the implementation of contact tracing and Leprosy Post Exposure prophylaxis (LPEP) to interrupt the chain of transmission. To accelerate the uptake of this recommendati... Background: World Health Organization recommends the implementation of contact tracing and Leprosy Post Exposure prophylaxis (LPEP) to interrupt the chain of transmission. To accelerate the uptake of this recommendation, a cross-sectional study among contacts of leprosy patients was conducted to investigate the feasibility of integrating leprosy systematic contact tracing and post-exposure prophylaxis (PEP) into the routine leprosy control program. Methods: This was a mixed methods cross-sectional study. The study was implemented in Kumi, Ngora, Serere, Soroti, Budaka and Kibuku Districts. Results: The 45 enrolled index patients (97.8% of the registered) identified a total of 135 contacts, of which 134 (99·2%) consented and were screened. Among them, one new leprosy patient was identified and started on treatment with multidrug therapy (MDT). All the eligible contacts, received the prophylactic treatment with Single Dose Rifampicin (SDR). Overall, SDR was administered to 133(98.5% of the listed contacts) with no adverse event reported. Factors associated with successful contact investigation and management included: Involvement of index patients, health care workers during the contact screening and SDR A administration, counselling of the index patients and contacts by the health care works, LPEP being administered as Directly observed Therapy (DOT) among others. Results Interpretation: The integration of leprosy post-exposure prophylaxis with administration of SDR and contact tracing is feasible, generally accepted by the patient, their contacts and health workers and can be integrated into the National Leprosy control programmes with minimal additional efforts once contact tracing has been established. Therefore, we recommend integration of administration of SDR in to the routine leprosy control program. 展开更多
关键词 LEPROSY Post Exposure Prophylaxis Single Dose Rifampicin
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Management strategies for common viral infections in pediatric renal transplant recipients
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作者 Randula Ranawaka Kavinda Dayasiri +1 位作者 Erandima Sandamali Manoji Gamage 《World Journal of Transplantation》 2024年第1期62-71,共10页
Viral infections have been considered as a major cause of morbidity and mortality after kidney transplantation in pediatric cohort.Children are at high risk of acquiring virus-related complications due to immunologica... Viral infections have been considered as a major cause of morbidity and mortality after kidney transplantation in pediatric cohort.Children are at high risk of acquiring virus-related complications due to immunological immaturity and the enhanced alloreactivity risk that led to maintenance of high immunosuppressive regimes.Hence,prevention,early detection,and prompt treatment of such infections are of paramount importance.Among all viral infections,herpes viruses(herpes simplex virus,varicella zoster virus,Epstein-Barr virus,cytomegalovirus),hepatitis B and C viruses,BK polyomavirus,and respiratory viruses(respiratory syncytial virus,parainfluenza virus,influenza virus and adenovirus)are common in kidney transplant recipients.These viruses can cause systemic disease or allograft dysfunction affecting the clinical outcome.Recent advances in technology and antiviral therapy have improved management strategies in screening,monitoring,adoption of prophylactic or preemptive therapy and precise treatment in the immunocompromised host,with significant impact on the outcome.This review discusses the etiology,screening and monitoring,diagnosis,prevention,and treatment of common viral infections in pediatric renal transplant recipients. 展开更多
关键词 Viral infections Post renal transplant Immunosuppressive regimes Herpes simplex virus Varicella zoster virus Epstein-Barr virus CYTOMEGALOVIRUS Hepatitis B virus BK polyomavirus Viral monitoring
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Advances in Research of Post Embolism Syndrome after Transarterial Chemoembolization(TACE)for Hepatocellular Carcinoma
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作者 Jimusi Sarengerile 《Medicinal Plant》 2024年第2期77-79,共3页
This article reviews the concept and clinical manifestations of post embolism syndrome after transarterial chemoembolization(TACE),and the prevention or timely intervention of post embolism syndrome in advance is expe... This article reviews the concept and clinical manifestations of post embolism syndrome after transarterial chemoembolization(TACE),and the prevention or timely intervention of post embolism syndrome in advance is expected to reduce its incidence and degree in clinical treatment,and to improve the quality of treatment of Hepatocellular Carcinoma Carcinoma(HCC). 展开更多
关键词 Hepatocellular Carcinoma(HCC) Transarterial chemoembolization(TACE) Post embolism syndrome(PES)
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Precision in detecting colon lesions:A key to effective screening policy but will it improve overall outcomes?
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作者 Luis Ramon Rabago Maria Delgado Galan 《World Journal of Gastrointestinal Endoscopy》 2024年第3期102-107,共6页
Colonoscopy is the gold standard for the screening and diagnosis of colorectal cancer,resulting in a decrease in the incidence and mortality of colon cancer.However,it has a 21%rate of missed polyps.Several strategies... Colonoscopy is the gold standard for the screening and diagnosis of colorectal cancer,resulting in a decrease in the incidence and mortality of colon cancer.However,it has a 21%rate of missed polyps.Several strategies have been devised to increase polyp detection rates and improve their characterization and delimi-tation.These include chromoendoscopy(CE),the use of other devices such as Endo cuffs,and major advances in endoscopic equipment[high definition,magnification,narrow band imaging,i-scan,flexible spectral imaging color enhancement,texture and color enhancement imaging(TXI),etc.].In the retrospective study by Hiramatsu et al,they compared white-light imaging with CE,TXI,and CE+TXI to determine which of these strategies allows for better definition and delimitation of polyps.They concluded that employing CE associated with TXI stands out as the most effective method to utilize.It remains to be demonstrated whether these results are extrapolatable to other types of virtual CE.Additionally,further investigation is needed in order to ascertain whether this strategy could lead to a reduction in the recurrence of excised lesions and potentially lower the occurrence of interval cancer. 展开更多
关键词 Colonoscopy screening Interval colorectal cancer Post colonoscopy colorectal cancer CHROMOENDOSCOPY Virtual chromoendoscopy high-definition whitelight endoscopy Texture and color enhancement imaging Indigo carmine ADENOMA Sessile serrated lesion
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Renal Transplant Artery Stenosis: Clinical Manifestations, Diagnosis and Treatment
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作者 Rihab Dkhissi Latifa Driouch +2 位作者 Naima Ouzeddoun Loubna Benamar Tarik Bouattar 《Open Journal of Nephrology》 2024年第2期262-274,共13页
Introduction: Renal transplant artery stenosis (RTAS) is a common and early complication of renal transplantation, which can lead to severe post-transplant hypertension, as well as significant morbidity and mortality,... Introduction: Renal transplant artery stenosis (RTAS) is a common and early complication of renal transplantation, which can lead to severe post-transplant hypertension, as well as significant morbidity and mortality, particulary graft loss. The aim of this study is to determine the prevalence, clinico-radiological characteristics and evaluate the outcomes of luminal angioplasty as a first-line treatment for RTAS, through the analysis of medical records of 27 kidney transplant patients. Material and Methods: This is a retrospective, single-center, and descriptive study conducted at the Nephrology department of the Ibn-Sina Hospital in Rabat, including 27 renal transplant patients with RTAS during the period from 1998 to 2023. All patients with clinically suspected RTAS and confirmed by Doppler ultrasound of the transplanted renal artery were included in the study. Results: The mean age of donors was 48.66 ± 13.55 years, with a female predominance (65%). The donor was deceased in 15% of cases. The mean age of the recipients was 39 ± 16 years with a male-to-female ratio of 4.4. The median onset of RTAS was 3.6 ± 3.4 months after renal transplantation. Seven patients (26%) had high blood pressure (HBP) before their transplantation. Six patients (22%) had hypertriglyceridemia and 7 patients (26%) had pure hypercholesterolemia. The main clinical signs were worsening of preexisting HBP, de novo HBP and acute renal failure (ARF). Stenosis was confirmed by renal Doppler ultrasound in all patients. It was severe in 63%, with a stenosis degree greater than 70%. Six patients underwent angioplasty, resulting in the stabilization of graft function with a nadir of 15 mg/l creatinine and blood pressure control with dual therapy in 5 patients. No graft loss cases were noted. Conclusion: RTAS is a significant vascular complication of renal transplantation that predicts unfavorable outcomes for both the patient and the graft. Early diagnosis is crucial to successfully restore graft function and prevent complications. 展开更多
关键词 RTAS Post Transplant Hypertension Graft Function Luminal Angioplasty
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