A multi-variable non-singular boundary element method (MNBEM) is presented for 2-D potential problems. This method is based on the coincident collocation of non-singular boundary integral equations (BIEs) of the pot...A multi-variable non-singular boundary element method (MNBEM) is presented for 2-D potential problems. This method is based on the coincident collocation of non-singular boundary integral equations (BIEs) of the potential and its derivatives, where the nodal potential derivatives are considered independent of the nodal potential and flux. The system equation is solved to determine the unknown boundary potentials and fluxes, with high accuracy boundary nodal potential derivatives obtained from the solution at the same time. A modified Gaussian elimination algorithm was developed to improve the solution efficiency of the final system equation. Numerical examples verify the validity of the proposed algorithm.展开更多
Diagnosis of mitochondrial DNA（mt DNA）disorders has traditionally been focused on the presence of point mutations and large deletions.However,deviations in mitochondrial abundance or mt DNA copy number can also be a...Diagnosis of mitochondrial DNA（mt DNA）disorders has traditionally been focused on the presence of point mutations and large deletions.However,deviations in mitochondrial abundance or mt DNA copy number can also be associated with many physiological and pathological conditions（Bai and Wong,2005）.展开更多
基金Supported by the National Natural Science Foundation of China(No. 10102019) the Special Fund for Returning Scholars in the Chinese Academy of Sciences (No. 20010826214905) and the Ministry of Education of China
文摘A multi-variable non-singular boundary element method (MNBEM) is presented for 2-D potential problems. This method is based on the coincident collocation of non-singular boundary integral equations (BIEs) of the potential and its derivatives, where the nodal potential derivatives are considered independent of the nodal potential and flux. The system equation is solved to determine the unknown boundary potentials and fluxes, with high accuracy boundary nodal potential derivatives obtained from the solution at the same time. A modified Gaussian elimination algorithm was developed to improve the solution efficiency of the final system equation. Numerical examples verify the validity of the proposed algorithm.
文摘Diagnosis of mitochondrial DNA（mt DNA）disorders has traditionally been focused on the presence of point mutations and large deletions.However,deviations in mitochondrial abundance or mt DNA copy number can also be associated with many physiological and pathological conditions（Bai and Wong,2005）.
