The emerging development of Extractive Reference Substance (ERS) is a methodology that meets the needs for quality control for Chinese Herbal Medicines (CHM) and respects the holistic viewpoint of Traditional Chinese ...The emerging development of Extractive Reference Substance (ERS) is a methodology that meets the needs for quality control for Chinese Herbal Medicines (CHM) and respects the holistic viewpoint of Traditional Chinese Medicine (TCM) and its clinical use of multiple ingredients with synergistic effects. The convention of using just a selected few Chemical Reference Substances (CRS) cannot adequately assess the quality of intact CHM. A validated chemical spectrum of an ERS provides the global characteristics in order to more specifically identify and assess targeted CHM. This paper describes the fundamental concepts, potential significance, and basic criteria of ERS, along with methods of preparation and calibration. Given the diversity of CHM, the various problems that will occur in establishing the proper process of ERS will need to be solved in a step by step manner. The ERSs of Ziziphi spinosae semen and ERS of Fritillaria thunbergii bulbus are given as examples of the development of ERS and demonstrate why we are optimistic about the utility of this approach.展开更多
目的探讨超声引导下弓状韧带上腰方肌阻滞与后路腰方肌阻滞对腹腔镜下直肠癌根治术患者术后镇痛效果及恢复质量的影响。方法选择拟行腹腔镜下直肠癌根治术患者80例,随机将患者分为两组:外侧弓状韧带上腰方肌前侧阻滞组(A组)和后路腰方...目的探讨超声引导下弓状韧带上腰方肌阻滞与后路腰方肌阻滞对腹腔镜下直肠癌根治术患者术后镇痛效果及恢复质量的影响。方法选择拟行腹腔镜下直肠癌根治术患者80例,随机将患者分为两组:外侧弓状韧带上腰方肌前侧阻滞组(A组)和后路腰方肌阻滞组(Q组),每组40例。比较两组患者术后48 h舒芬太尼消耗量、术后24 h QoR⁃40评分、首次按压镇痛泵时间、术后静息和运动状态VAS评分、术后48 h补救镇痛发生率、镇痛满意度、术后早期恢复情况及不良反应发生情况。结果与Q组相比,A组患者术后48 h舒芬太尼总消耗量明显降低(P<0.001);A组患者术后6、12、24 h静息与运动状态VAS评分均明显降低(P<0.05);A组患者术后首次按压镇痛泵时间明显晚于Q组(P<0.05);A组患者术后24 h QoR⁃40评分明显高于Q组(P<0.001);两组患者术后48 h补救镇痛发生率、镇痛满意度、首次排气时间、首次下床活动时间、术后恶心呕吐及其他不良反应差异无统计学意义(P>0.05)。结论在腹腔镜下直肠癌根治术中,相较于后路腰方肌阻滞,超声引导下弓状韧带上腰方肌阻滞可以提供更好的镇痛效果,减少患者术后阿片类药物用量,提高患者术后恢复质量。展开更多
文摘The emerging development of Extractive Reference Substance (ERS) is a methodology that meets the needs for quality control for Chinese Herbal Medicines (CHM) and respects the holistic viewpoint of Traditional Chinese Medicine (TCM) and its clinical use of multiple ingredients with synergistic effects. The convention of using just a selected few Chemical Reference Substances (CRS) cannot adequately assess the quality of intact CHM. A validated chemical spectrum of an ERS provides the global characteristics in order to more specifically identify and assess targeted CHM. This paper describes the fundamental concepts, potential significance, and basic criteria of ERS, along with methods of preparation and calibration. Given the diversity of CHM, the various problems that will occur in establishing the proper process of ERS will need to be solved in a step by step manner. The ERSs of Ziziphi spinosae semen and ERS of Fritillaria thunbergii bulbus are given as examples of the development of ERS and demonstrate why we are optimistic about the utility of this approach.
文摘目的探讨超声引导下弓状韧带上腰方肌阻滞与后路腰方肌阻滞对腹腔镜下直肠癌根治术患者术后镇痛效果及恢复质量的影响。方法选择拟行腹腔镜下直肠癌根治术患者80例,随机将患者分为两组:外侧弓状韧带上腰方肌前侧阻滞组(A组)和后路腰方肌阻滞组(Q组),每组40例。比较两组患者术后48 h舒芬太尼消耗量、术后24 h QoR⁃40评分、首次按压镇痛泵时间、术后静息和运动状态VAS评分、术后48 h补救镇痛发生率、镇痛满意度、术后早期恢复情况及不良反应发生情况。结果与Q组相比,A组患者术后48 h舒芬太尼总消耗量明显降低(P<0.001);A组患者术后6、12、24 h静息与运动状态VAS评分均明显降低(P<0.05);A组患者术后首次按压镇痛泵时间明显晚于Q组(P<0.05);A组患者术后24 h QoR⁃40评分明显高于Q组(P<0.001);两组患者术后48 h补救镇痛发生率、镇痛满意度、首次排气时间、首次下床活动时间、术后恶心呕吐及其他不良反应差异无统计学意义(P>0.05)。结论在腹腔镜下直肠癌根治术中,相较于后路腰方肌阻滞,超声引导下弓状韧带上腰方肌阻滞可以提供更好的镇痛效果,减少患者术后阿片类药物用量,提高患者术后恢复质量。