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Parameter identifiability of a within-host SARS-CoV-2 epidemic model
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作者 Junyuan Yang Sijin Wu +3 位作者 Xuezhi Li Xiaoyan Wang Xue-Song Zhang Lu Hou 《Infectious Disease Modelling》 CSCD 2024年第3期975-994,共20页
Parameter identification involves the estimation of undisclosed parameters within a system based on observed data and mathematical models.In this investigation,we employ DAISY to meticulously examine the structural id... Parameter identification involves the estimation of undisclosed parameters within a system based on observed data and mathematical models.In this investigation,we employ DAISY to meticulously examine the structural identifiability of parameters of a within-host SARS-CoV-2 epidemic model,taking into account an array of observable datasets.Furthermore,Monte Carlo simulations are performed to offer a comprehensive practical analysis of model parameters.Lastly,sensitivity analysis is employed to ascertain that decreasing the replication rate of the SARS-CoV-2 virus and curbing the infectious period are the most efficacious measures in alleviating the dissemination of COVID-19 amongst hosts. 展开更多
关键词 Structural identifiability practical identifiability Sensitivity analysis The basic reproduction number
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Identifiability Analysis of Load Model Parameters by Estimating Confidential Intervals 被引量:3
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作者 Xinran Zhang Chao Lu +3 位作者 Ying Wang Qiantu Ruan Hongbo Ye Weihong Wang 《CSEE Journal of Power and Energy Systems》 SCIE EI CSCD 2023年第5期1666-1675,共10页
The identification of load model parameters from practical measurement data has become an essential method to build load models for power system simulation,analysis and control.In practical situations,the accuracy of ... The identification of load model parameters from practical measurement data has become an essential method to build load models for power system simulation,analysis and control.In practical situations,the accuracy of the load model parameters identification results is impacted by data quality and measurement accuracy,which leads to the problem of identifiability.In this paper,an identifiability analysis methodology of load model parameters,by estimating the confidential intervals(CIs)of the parameters,is proposed.The load model structure and the combined optimization and regression method to identify the parameters are first introduced.Then,the definition and analysis method of identifiability are discussed.The CIs of the parameters are estimated through the profile likelihood method,based on which a practical identifiability index(PII)is defined to quantitatively evaluate identifiability.Finally,the effectiveness of the proposed analysis approach is validated by the case study results in a practical provincial power grid.The results show that the impact of various disturbance magnitudes,measurement errors and data length can all be reflected by the proposed PII.Furthermore,the proposed PII can provide guidance in data length selection in practical load model identification situations. 展开更多
关键词 Confidential interval Load modeling parameter estimation practical identifiability
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