动脉粥样硬化是心血管疾病重要的病理生理基础,延缓和防治动脉粥样硬化对于减少和降低心血管疾病的发病率及病死率具有重要意义。高密度脂蛋白(high density lipoprotein,HDL)通过参与介导胆固醇逆向转运(reverse cholesterol transport...动脉粥样硬化是心血管疾病重要的病理生理基础,延缓和防治动脉粥样硬化对于减少和降低心血管疾病的发病率及病死率具有重要意义。高密度脂蛋白(high density lipoprotein,HDL)通过参与介导胆固醇逆向转运(reverse cholesterol transport,RCT)在抗动脉粥样硬化的形成和进展中发挥了重要作用。Preβ-1高密度脂蛋白(prebeta-1 high density lipoprotein,Preβ-1HDL)作为HDL的一种亚类,是外周细胞移出胆固醇的最初接受体,直接参与了RCT的起始步骤,并在随后的胆固醇酯化及转运中起着重要作用。本文就Preβ-1HDL的结构、代谢及其与心血管疾病的关系作一简要综述。展开更多
Whitebark pine （Pinus albicaulis） populations are in decline across the species＇ range due to historic wildfire exclusion, mountain pine beetle （Dendroctonus ponderosae, MPB） outbreaks, and an invasive fungal pat...Whitebark pine （Pinus albicaulis） populations are in decline across the species＇ range due to historic wildfire exclusion, mountain pine beetle （Dendroctonus ponderosae, MPB） outbreaks, and an invasive fungal pathogen causing the disease white pine blister rust （Cronartium ribicola, WPBR）. Despite reliance on stand- replacing fires, information on whitebark pine regeneration occurrence is limited and the trajectory of future forests is largely unknown in some areas of the range. Regeneration densities were assessed in burned and adjacent non-burned areas at six high elevation locations in northwest Wyoming where stand-replacing fires occurred 8-32 years before thesurveys. In these locations at the eastern extent of the species range, we assessed what site factors were associ- ated with regeneration success. Whitebark pine regen- eration density was greater and seedlings were older in non-burned compared to burned areas. Within burns, north aspects had more regeneration than south aspects. Potential seed source densities and other species＇ regeneration were positively related to whitebark p^ne regeneration densities in burned areas. South facing slopes or grass covered areas may have either delayed or no regeneration of whitebark pine without the help of artificial planting.展开更多
文摘动脉粥样硬化是心血管疾病重要的病理生理基础,延缓和防治动脉粥样硬化对于减少和降低心血管疾病的发病率及病死率具有重要意义。高密度脂蛋白(high density lipoprotein,HDL)通过参与介导胆固醇逆向转运(reverse cholesterol transport,RCT)在抗动脉粥样硬化的形成和进展中发挥了重要作用。Preβ-1高密度脂蛋白(prebeta-1 high density lipoprotein,Preβ-1HDL)作为HDL的一种亚类,是外周细胞移出胆固醇的最初接受体,直接参与了RCT的起始步骤,并在随后的胆固醇酯化及转运中起着重要作用。本文就Preβ-1HDL的结构、代谢及其与心血管疾病的关系作一简要综述。
基金supported by USDA Forest Service,Region 1 and 4,Whitebark Pine Restoration Fund,Agreement No.07-CA-11010000-009the Colorado State University,Agricultural Experiment Station
文摘Whitebark pine （Pinus albicaulis） populations are in decline across the species＇ range due to historic wildfire exclusion, mountain pine beetle （Dendroctonus ponderosae, MPB） outbreaks, and an invasive fungal pathogen causing the disease white pine blister rust （Cronartium ribicola, WPBR）. Despite reliance on stand- replacing fires, information on whitebark pine regeneration occurrence is limited and the trajectory of future forests is largely unknown in some areas of the range. Regeneration densities were assessed in burned and adjacent non-burned areas at six high elevation locations in northwest Wyoming where stand-replacing fires occurred 8-32 years before thesurveys. In these locations at the eastern extent of the species range, we assessed what site factors were associ- ated with regeneration success. Whitebark pine regen- eration density was greater and seedlings were older in non-burned compared to burned areas. Within burns, north aspects had more regeneration than south aspects. Potential seed source densities and other species＇ regeneration were positively related to whitebark p^ne regeneration densities in burned areas. South facing slopes or grass covered areas may have either delayed or no regeneration of whitebark pine without the help of artificial planting.
