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Mechanism,prevention,and control of mining-induced dynamic disasters in underground metal mines in China:Challenges and solutions
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作者 LI Peng CAI Mei-feng +3 位作者 MIAO Sheng-jun REN Fen-hua GORJIAN Mostafa PENG Chao 《Journal of Central South University》 SCIE EI CAS CSCD 2024年第8期2549-2606,共58页
Metal mineral resources play an indispensable role in the development of the national economy.Dynamic disasters in underground metal mines seriously threaten mining safety,which are major scientific and technological ... Metal mineral resources play an indispensable role in the development of the national economy.Dynamic disasters in underground metal mines seriously threaten mining safety,which are major scientific and technological problems to be solved urgently.In this article,the occurrence status and grand challenges of some typical dynamic disasters involving roof falling,spalling,collapse,large deformation,rockburst,surface subsidence,and water inrush in metal mines in China are systematically presented,the characteristics of mining-induced dynamic disasters are analyzed,the examples of dynamic disasters occurring in some metal mines in China are summarized,the occurrence mechanism,monitoring and early warning methods,and prevention and control techniques of these disasters are highlighted,and some new opinions,suggestions,and solutions are proposed simultaneously.Moreover,some shortcomings in current disaster research are pointed out,and the direction of efforts to improve the prevention and control level of dynamic disasters in China’s metal mines in the future is prospected.The integration of forward-looking key innovative theories and technologies in the abovementioned aspects will greatly enhance the cognitive level of disaster prevention and mitigation in China’s metal mining industry and achieve a significant shift from passive disaster relief to active disaster prevention. 展开更多
关键词 underground metal mines dynamic disasters MECHANISM monitoring and early warning prevention and control
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Practice of Infection Prevention and Control Strategies in Risk Departments during the COVID-19 Epidemic
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作者 Minfang Wang Wenyi Ye +7 位作者 Jiefeng Huang Yuexian Zhu Xuxia Yu Hao Huang Fang Xu Bo Jin Ying Yang Tieer Gan 《Advances in Infectious Diseases》 CAS 2024年第1期1-12,共12页
Objective: To explore the practice and application of infection prevention and control strategies in risk departments during the COVID-19 epidemic, and to formulate the infection prevention and control measures to pro... Objective: To explore the practice and application of infection prevention and control strategies in risk departments during the COVID-19 epidemic, and to formulate the infection prevention and control measures to provide advice and guidance in risk departments. Methods: According to the latest plan of diagnosis and treatment, prevention and control issued by the National Health Commission, expert advice and consensus, combined with the actual situation in our hospital, a series of infection prevention and control measures of COVID-19 in risk department was formulated. Results: During the epidemic period, the prevention and control measures of nine risk departments including emergency operation, anesthesiology, endoscopy center, blood purification center, otolaryngology, stomatology, medical imaging department, medical cosmetology department and pulmonary function room were established from six aspects, including pre-examination and screening, medical technology control, personnel management, personal protection, environmental disinfection, medical waste disposal, etc. Conclusion: During the epidemic period, the infection prevention and control strategy of risk departments is one of the key links to control the spread of the epidemic, and risk departments must pay attention to and strictly implement various infection prevention and control measures. 展开更多
关键词 COVID-19 Risk Department Infection prevention and control STRATEGY PRACTICE
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Prevention and Control Strategies of Nosocomial Infection and Effectiveness Evaluation in a Tertiary Teaching Hospital during the Epidemic of COVID-19
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作者 Minfang Wang Wenyi Ye +7 位作者 Zhe Han Lu Yang Dawei Huang Xuxia Yu Yuexian Zhu Shuangying Huang Ying Yang Tieer Gan 《Advances in Infectious Diseases》 CAS 2024年第1期233-247,共15页
Objective: To evaluate the role of prevention and control strategies for nosocomial infection in a tertiary teaching hospital during the sudden outbreak of Corona Virus Disease 2019 (COVID-19). Methods: The hospital i... Objective: To evaluate the role of prevention and control strategies for nosocomial infection in a tertiary teaching hospital during the sudden outbreak of Corona Virus Disease 2019 (COVID-19). Methods: The hospital initiated an emergency plan involving multi-departmental defense and control. It adopted a series of nosocomial infection prevention and control measures, including strengthening pre-examination and triage, optimizing the consultation process, improving the hospital’s architectural composition, implementing graded risk management, enhancing personal protection, and implementing staff training and supervision. Descriptive research was used to evaluate the short-term effects of these in-hospital prevention and control strategies. The analysis compared changes in related evaluation indicators between January 24, 2020 and February 12, 2020 (Chinese Lunar New Year’s Eve 2020 to lunar January 19) and the corresponding lunar period of the previous year. Results: Compared to the same period last year, the outpatient fever rate increased by 1.85-fold (P P Conclusion: The nosocomial infection prevention and control strategies implemented during this specific period improved the detection and control abilities for the COVID-19 source of infection and enhanced the compliance with measures. This likely contributed significantly to avoiding the occurrence of nosocomial infection. 展开更多
关键词 Corona Virus Disease 2019 Nosocomial Infection prevention and control Strategy Effectiveness Evaluation
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Infection control and prevention in burn victims:The role of nurses
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作者 Dorcas Ayomikun ARIYO Olaolorunpo OLORUNFEMI 《Journal of Integrative Nursing》 2024年第2期136-141,共6页
Burn injury is a major public health concern,with an estimated 180,000 deaths each year associated with burn-related infections.The majority of these occur in low-and middle-income countries,and almost two-thirds occu... Burn injury is a major public health concern,with an estimated 180,000 deaths each year associated with burn-related infections.The majority of these occur in low-and middle-income countries,and almost two-thirds occur in the World Health Organization African and South-East Asia Regions.There is a risk of an escalation of burn injury site infections if nurses who are directly involved in burn care do not develop a mechanism to mitigate this risk in the coming years.Hence,this study aims at explaining what burn injuries are and how nurses can prevent the occurrence of infection among burn victims.This review analyzed published studies using keywords such as burn injury,infection in burn patients,and nurses’involvement in infection prevention and control(IPC)on search engines such as PubMed,Science Direct,and Google Scholar.The literature was retrieved and reviewed for eligibility to capture just the variables indicated in this seminar objective;the date range chosen in the literature search was from 2015 to 2023.The study found that many patients die from burn injuries as a result of exposure to infection and most nurses are not adequately informed about infection control.The study also found that nurses’responsibilities include proper hand hygiene,wound care,the use of personal protective equipment,antibiotic medication,cleaning the patient’s surroundings,and preventing patient cross-contamination.Burn injuries pose a significant risk to patients,necessitating infection control and prevention.Therefore,nurses in burn units should be informed on IPC practices and also educate patients,families,and coworkers on their importance. 展开更多
关键词 Burn injury control holistic nursing care infection prevention nurses PRACTICES
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Technical Points of Green Prevention and Control Technology of Major Diseases and Pests in Lixian Rhubarb(Rheum palmatum L.)
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作者 Shuizhan PAN Lianhu SUN +2 位作者 Minyan LIU Zhenkun WANG Yicun WANG 《Plant Diseases and Pests》 2024年第1期22-25,共4页
Based on different types of diseases,pests and weeds in the whole growth period of rhubarb(sowing period-harvesting period),the corresponding green prevention and control technology is proposed,aiming to further reduc... Based on different types of diseases,pests and weeds in the whole growth period of rhubarb(sowing period-harvesting period),the corresponding green prevention and control technology is proposed,aiming to further reduce the application amount of pesticides and fertilizers in the production of medicinal sources of Lixian rhubarb during the"14 th Five-Year Plan"period.The results will provide a theoretical basis for increasing the promotion and application of agricultural prevention and control(including disease-resistant varieties,ecological regulation),physical prevention and control,biological prevention and control measures,thus ensuring effective protection of the ecological environment,green,healthy and sustainable development of traditional Chinese medicine agriculture in Longnan,and source quality of authentic medicinal materials. 展开更多
关键词 Lixian rhubarb Disease PEST WEED Green prevention and control
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Major Diseases and Pests of Blueberry in Guizhou Province and Progress in Their Prevention and Control
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作者 Yanling REN Shoumei WAN +10 位作者 Tao WANG Min ZHANG Lidan MA Zhi LI Youwen TIAN Haibin FU Xingning WANG Jing PENG Lingling XIAO Dandan LU Jinyu ZHAO 《Plant Diseases and Pests》 2024年第3期1-4,7,共5页
As the blueberry industry continues to evolve,the effective control of its diseases and pests has become an essential component of local agricultural development.This paper provides a comprehensive overview of the pri... As the blueberry industry continues to evolve,the effective control of its diseases and pests has become an essential component of local agricultural development.This paper provides a comprehensive overview of the principal types of blueberry diseases and pests in Guizhou Province,along with the corresponding control measures,in order to serve as a valuable reference for blueberry growers. 展开更多
关键词 BLUEBERRIES Diseases and pests prevention and control Guizhou Province
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Occurrence Regularity and Comprehensive Prevention and Control Techniques of Sunflower Downy Mildew
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作者 Weidong SHAN Yantao LIU +5 位作者 Wei DUAN Huping ZHANG Shengli LIU Peng WANG Zhonghua LEI Lanlan ZHANG 《Plant Diseases and Pests》 2024年第5期8-10,18,共4页
This paper examines the occurrence regularity and comprehensive prevention and control techniques for sunflower downy mildew.It provides a detailed discussion of the pathogens,symptoms,and associated risks,as well as ... This paper examines the occurrence regularity and comprehensive prevention and control techniques for sunflower downy mildew.It provides a detailed discussion of the pathogens,symptoms,and associated risks,as well as the transmission pathways,underlying causes,and prevention and control techniques related to sunflower downy mildew.The aim is to offer valuable references and technical guidance for the effective management of this disease. 展开更多
关键词 SUNFLOWER Downy mildew Occurrence regularity prevention and control technique
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Comprehensive Prevention and Control Technology of Vegetable Diseases and Pests in Shandong Province
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作者 Dongwen SUN Hui YU +7 位作者 Yang QIN Yujie LIN Xiaomeng QI Yuxuan CHEN Yuxin HE Xinying YAN Jia'er XU Shumei GUO 《Plant Diseases and Pests》 2024年第1期26-27,32,共3页
An in-depth research and practice has been conducted on vegetable diseases and pests in Shandong Province,and the principles of comprehensive and ecological control of diseases and pests are put forward,including agri... An in-depth research and practice has been conducted on vegetable diseases and pests in Shandong Province,and the principles of comprehensive and ecological control of diseases and pests are put forward,including agricultural control measures such as crop rotation,field cleaning,fertilizer and water management,physical control measures such as catching and killing,trapping,blocking,photoelectric energy treatment,biological control measures such as the use of natural enemies,pathogenic microorganisms,other beneficial organisms and metabolites,and scientific and rational chemical control measures.Comprehensive prevention and control not only controls vegetable diseases and pests effectively,but also protects the ecological environment. 展开更多
关键词 VEGETABLE Diseases and pests Comprehensive prevention and control
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Establishment and Application of Prevention and Control Techniques of New Sugarcane White Leaf Disease
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作者 Xiaoyan WANG Ruonan QIU +8 位作者 Hong XU Yulong JIANG Rongyue ZHANG Fengyun ZHANG Ming GONG Jinxue LEI Hongli SHAN Jie LI Yingkun HUANG 《Agricultural Biotechnology》 2024年第4期18-20,27,共4页
Aiming at the basic and key technical problems in prevention and control of sugarcane white leaf disease(SCWL),this study systematically overcame key technical bottleneck of prevention and control of new SCWL after 10... Aiming at the basic and key technical problems in prevention and control of sugarcane white leaf disease(SCWL),this study systematically overcame key technical bottleneck of prevention and control of new SCWL after 10 years of collaborative research,and achieved several innovative achievements.SCWL phytoplasmas newly recorded in China and the new subgroup of SCWL phytoplasmas(16SrXI-D)were discovered for the first time in Yunnan,and the whole genome analysis of the epidemic subgroup was completed.The main transmission source of SCWL pathogens has been identified as infected seed canes,and Tettigoniella viridis and Clovia conifer were newly discovered as vectors for virus transmission.The disease resistance of 25 main varieties was identified,and 10 control varieties were selected.The prevention and control strategy of"emphasizing early warning,strictly carrying out quarantine,blocking the vectors and controlling residual plants"was put forward,and a comprehensive prevention technique was established through integration of various techniques,and standardized technical regulations were formulated for demonstration application.The promotion and application of these achievements have realized scientific prevention and control of SCWL,effectively curbed the spread of SCWL,and ensured the safety of sugarcane producing areas in China,achieving great economic,social and ecological benefits and providing technical support for high-quality development,loss reduction and efficiency improvement of China's sugar industry. 展开更多
关键词 Sugarcane white leaf disease Comprehensive prevention and control APPLICATION
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Integrated Prevention and Control Technology for Coffee Leaf Rust in Yunnan Province
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作者 Xingfei FU Guiping LI Faguang HU 《Asian Agricultural Research》 2024年第11期25-28,共4页
This paper investigates the damage symptoms and occurrence regularity related to coffee leaf rust,and proposes a comprehensive prevention and control strategy grounded in the principle of prioritizing prevention and i... This paper investigates the damage symptoms and occurrence regularity related to coffee leaf rust,and proposes a comprehensive prevention and control strategy grounded in the principle of prioritizing prevention and implementing integrated prevention and control.This strategy encompasses the cultivation of rust-resistant varieties,the implementation of agricultural practices,the application of chemical interventions,the utilization of hyperparasitic fungi,and the protection and utilization of natural enemies.The paper further outlines the necessary requirements for effective prevention and control,emphasizing the importance of enhancing responsibility implementation,fostering systematic prevention and control measures,enhancing guidance services,and increasing publicity and guidance.The aim is to offer technical guidance for the integrated prevention and control of coffee leaf rust in Yunnan Province. 展开更多
关键词 Coffee leaf rust disease Damage symptoms Occurrence regularity Integrated prevention and control Yunnan Province
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The Research on the Paths of Popular Science Education about Myopia Prevention and Control among College Students in the Context of Shifting the Focus Forward
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作者 Shengpo Zeng Yang’ai Gu 《Open Journal of Applied Sciences》 2024年第2期371-378,共8页
Currently, the number of myopic people in China has reached as high as 600 million, and it shows a trend of “early onset, high incidence, and a high degree of severity”. The issue of myopia among children and adoles... Currently, the number of myopic people in China has reached as high as 600 million, and it shows a trend of “early onset, high incidence, and a high degree of severity”. The issue of myopia among children and adolescents has attracted widespread attention from all sectors of society. Comprehensive myopia prevention and control efforts have been launched nationwide. Popular science education, vision screening, and improving visual environments are effective measures for preventing myopia. However, among the target audience for comprehensive myopia prevention and control, the preschool children group has been neglected, and the work of myopia prevention and control for this group has been significantly weakened and marginalized. Due to insufficient awareness of prevention and control, the hyperopia reserve in the preschool children group is being continuously depleted, leading to the early onset of myopia. In light of this situation, the focus of myopia prevention and control needs to shift forward, and it is worth exploring and pondering how college students with a background in optometry can develop entertaining and engaging popular science education materials and methods. 展开更多
关键词 Myopia prevention and control Popular Science Education Hyperopia Reserve Eye Health Preschool Children Group
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Field Prevention and Control of Tobacco Black Shank in Guizhou Province
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作者 Yingjie JIANG Yongmo LI +2 位作者 Jun ZHOU Laifu LUO Yinsheng WANG 《Plant Diseases and Pests》 2024年第5期11-14,23,共5页
[Objectives]The paper was to explore the prevention and therapeutic schedule of tobacco black shank.[Methods]Different concentrations of 25 g/L fludioxonil·37.5 g/L metalaxyl-M,10 billion/mL Bacillus amyloliquefa... [Objectives]The paper was to explore the prevention and therapeutic schedule of tobacco black shank.[Methods]Different concentrations of 25 g/L fludioxonil·37.5 g/L metalaxyl-M,10 billion/mL Bacillus amyloliquefaciens,110 g/L amino acids·24 g/L manganese zinc,120 g/L calcium·20 g/L magnesium,and 4%metalaxyl-M·64%mancozeb were employed to assess their efficacy in controlling tobacco black shank.The disease index was subsequently evaluated.[Results]25 g/L fludioxonil·37.5 g/L metalaxyl-M+10 billion/mL B.amyloliquefaciens+110 g/L amino acids·24 g/L manganese zinc(transplanting dosage)or 120 g/L calcium·20 g/L magnesium(sealing dosage)(transplanting dosage:750 mL/hm 2+1.2×104 mL/hm 2+1.5×103 mL/hm 2,sealing dosage:1.5×103 mL/hm 2+1.2×104 mL/hm 2+1.5×103 mL/hm 2)resulted in a notable impact on the prevention of tobacco black shank.The incidence in the treated area was 10.78%,a 35.72%reduction compared to the control.The estimated yield was 99700 yuan/hm 2,a 34.91%increase compared to the control.25 g/L fludioxonil·37.5 g/L metalaxyl-M+10 billion/mL B.amyloliquefaciens+120 g/L calcium·20 g/L magnesium+4%metalaxyl-M·64%mancozeb(control dosage:1.5×103 mL/hm 2+1.2×104 mL/hm 2+1.5×103 mL/hm 2+1.5×103 g/hm 2,1.5×103 mL/hm 2+1.2×104 mL/hm 2+1.5×103 mL/hm 2+1.5×103 g/hm 2,with an interval of 7 d between applications)demonstrated a significant efficacy in controlling tobacco black shank.At 7 d following the second application,the relative preventive efficacy was observed to be 88.99%.Additionally,the estimated yield was 109900 yuan/hm 2,representing an increase of 244.51%compared to the control.[Conclusions]During the transplanting and sealing stages,25 g/L fludioxonil·37.5 g/L metalaxyl-M+10 billion/mL B.amyloliquefaciens+110 g/L amino acids·24 g/L manganese zinc(transplanting dosage)or 120 g/L calcium·20 g/L magnesium(sealing dosage)may be employed to enhance the growth of tobacco plants and mitigate the occurrence of tobacco black shank.Additionally,25 g/L fludioxonil·37.5 g/L metalaxyl-M+10 billion/mL B.amyloliquefaciens+120 g/L calcium·20 g/L magnesium+4%metalaxyl-M·64%mancozeb can be utilized for the treatment of tobacco black shank during the initial incidence stage. 展开更多
关键词 Tobacco black shank prevention TREATMENT FIELD
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Traditional Chinese medicine: empowering tuberculosis prevention and control
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作者 Fang-Xiang Yu Wei Bi Xin-Ju Li 《Infectious Diseases Research》 2024年第2期22-23,共2页
Dear Editor,Tuberculosis(TB)is an airborne chronic infectious disease,posing long-lasting challenges and causing extensive health crises and deaths to humanity throughout history,despite existing prevention and treatm... Dear Editor,Tuberculosis(TB)is an airborne chronic infectious disease,posing long-lasting challenges and causing extensive health crises and deaths to humanity throughout history,despite existing prevention and treatment methods.The latest TB statistics report released by the World Health Organization in 2023 pointed out that,in 2022,the world recorded approximately 10.6 million new confirmed cases of TB.Among them,China accounted for about 748,000,around 7.1%of the total[1]. 展开更多
关键词 prevention TUBERCULOSIS HUMANITY
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Internal Control Management and Risk Prevention Measures of State-Owned Enterprises
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作者 Bing Liu 《Journal of Electronic Research and Application》 2024年第3期1-6,共6页
As an important pillar of national economic development,state-owned enterprises,their operational efficiency,and risk management ability are directly related to the stability and security of the national economy.As an... As an important pillar of national economic development,state-owned enterprises,their operational efficiency,and risk management ability are directly related to the stability and security of the national economy.As an important part of enterprise management,internal control management plays an irreplaceable role.Especially in the current domestic and international economic situation is complex and changeable,market competition is increasingly fierce environment,to strengthen the internal control management of state-owned enterprises and risk prevention measures is particularly important.This paper starts with the importance of internal control management and risk prevention for state-owned enterprises,and analyzes the problems and strategies in the internal control management and risk prevention of state-owned enterprises,in order to build a more comprehensive and efficient risk management system for state-owned enterprises to adapt to the ever-changing market environment and realize sustainable development. 展开更多
关键词 State-owned enterprises Internal control management Risk prevention
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Combined prevention and treatment measures are essential to control nosocomial infections during the COVID-19 pandemic
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作者 Jing-Wen Liu Yue-Yue Li +1 位作者 Ming-Ke Wang Ji-Shun Yang 《World Journal of Virology》 2024年第2期11-18,共8页
Severe acute respiratory syndrome coronavirus-2 is a highly contagious positive-sense,single-stranded RNA virus that has rapidly spread worldwide.As of December 17,2023,772838745 confirmed cases including 6988679 deat... Severe acute respiratory syndrome coronavirus-2 is a highly contagious positive-sense,single-stranded RNA virus that has rapidly spread worldwide.As of December 17,2023,772838745 confirmed cases including 6988679 deaths have been reported globally.This virus primarily spreads through droplets,airborne transmission,and direct contact.Hospitals harbor a substantial number of confirmed coronavirus disease 2019(COVID-19)patients and asymptomatic carriers,accompanied by high population density and a larger susceptible population.These factors serve as potential triggers for nosocomial infections,posing a threat during the COVID-19 pandemic.Nosocomial infections occur to varying degrees across different countries worldwide,emphasizing the urgent need for a practical approach to prevent and control the intra-hospital spread of COVID-19.This study primarily concentrated on a novel strategy combining preventive measures with treatment for combating COVID-19 nosocomial infections.It suggests preventive methods,such as vaccination,disinfection,and training of heathcare personnel to curb viral infections.Additionally,it explored therapeutic strategies targeting cellular inflammatory factors and certain new medications for COVID-19 patients.These methods hold promise in rapidly and effectively preventing and controlling nosocomial infections during the COVID-19 pandemic and provide a reliable reference for adopting preventive measures in the future pandemic. 展开更多
关键词 COVID-19 SARS-CoV-2 Nosocomial infection prevention Treatment
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The Impact of Optimizing Details in the Operating Room on the Level of Knowledge, Attitude, and Practice of Hospital Infection Prevention and Control by Surgeons, as Well as the Effectiveness of Infection Control
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作者 Yuanyuan Zhang 《Surgical Science》 2024年第7期421-429,共9页
Objective: This paper aims to explore the impact of optimizing details in the operating room on the level of knowledge, attitude, and practice of hospital infection prevention and control by surgeons, as well as the e... Objective: This paper aims to explore the impact of optimizing details in the operating room on the level of knowledge, attitude, and practice of hospital infection prevention and control by surgeons, as well as the effectiveness of infection control. Methods: From January 2022 to June 2023, a total of 120 patients were screened and randomly divided into a control group (routine care and hospital infection management) and a study group (optimizing details in the operating room). Results: Significant differences were found between the two groups in the data of surgeons’ level of knowledge, attitude, and practice in hospital infection prevention and control, infection rates, and nursing satisfaction, with the study group showing better results (P Conclusion: The use of optimizing details in the operating room among surgeons can effectively improve surgeons’ level of knowledge, attitude, and practice in hospital infection prevention and control, reduce infection occurrence, and is worth promoting. 展开更多
关键词 Optimizing Details in the Operating Room Infection Level of Knowledge ATTITUDE and Practice Infection control
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Cervical cancer prevention in China: where are we now, and what's next? 被引量:2
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作者 Huijiao Yan Qiankun Wang Youlin Qiao 《Cancer Biology & Medicine》 SCIE CAS CSCD 2024年第3期213-217,共5页
Cervical cancer(CC) epidemiology CC, the fourth most frequently diagnosed malignancy in women worldwide, is a major global health challenge, particularly in low-resource regions. Approximately 88.1% of the 604,000 CC ... Cervical cancer(CC) epidemiology CC, the fourth most frequently diagnosed malignancy in women worldwide, is a major global health challenge, particularly in low-resource regions. Approximately 88.1% of the 604,000 CC new cases occurred in low-and middle-income countries in 2020, and more than 90% of the 342,000 CC deaths occurred in low-and middle-income countries in 2020~1. 展开更多
关键词 prevention CERVICAL EPIDEMIOLOGY
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Recent advances in promising drugs for primary prevention of gastroesophageal variceal bleeding with cirrhotic portal hypertension 被引量:1
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作者 Ji-Yao Sheng Zi-Fan Meng +1 位作者 Qiao Li Yong-Sheng Yang 《Hepatobiliary & Pancreatic Diseases International》 SCIE CAS CSCD 2024年第1期4-13,共10页
Background:Gastroesophageal variceal bleeding is one of the most severe complications of patients with cirrhosis.Although primary prevention drugs,including non-selectiveβ-blockers,have effectively reduced the incide... Background:Gastroesophageal variceal bleeding is one of the most severe complications of patients with cirrhosis.Although primary prevention drugs,including non-selectiveβ-blockers,have effectively reduced the incidence of bleeding,their efficacy is limited due to side effects and related contraindications.With recent advances in precision medicine,precise drug treatment provides better treatment efficacy.Data sources:Literature search was conducted in PubMed,MEDLINE and Web of Science for relevant articles published up to May 2022.Information on clinical trials was obtained from https://clinicaltrials.gov/and http://www.chictr.org.cn/.Results:The in-depth understanding of the pathogenesis and advances of portal hypertension has enabled the discovery of multiple molecular targets for promising drugs.According to the site of action,these drugs could be classified into four classes:intrahepatic,extrahepatic,both intrahepatic and extrahepatic targets and others.All these classes of drugs offer advantages over traditional treatments in prevention of gastroesophageal variceal bleeding in patients with cirrhotic portal hypertension.Conclusions:This review classified and summarized the promising drugs,which prevent gastroesophageal variceal bleeding by targeting specific markers of pathogenesis of portal hypertension,demonstrating the significance of using the precision medicine strategy to discover and develop promising drugs for the primary prevention of gastroesophageal variceal bleeding in patients with cirrhotic portal hypertension. 展开更多
关键词 Cirrhotic portal hypertension Target drug Primary prevention BLEEDING
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Adolescent suicide risk factors and the integration of socialemotional skills in school-based prevention programs 被引量:2
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作者 Xin-Qiao Liu Xin Wang 《World Journal of Psychiatry》 SCIE 2024年第4期494-506,共13页
Adolescents are considered one of the most vulnerable groups affected by suicide.Rapid changes in adolescents’physical and mental states,as well as in their lives,significantly and undeniably increase the risk of sui... Adolescents are considered one of the most vulnerable groups affected by suicide.Rapid changes in adolescents’physical and mental states,as well as in their lives,significantly and undeniably increase the risk of suicide.Psychological,social,family,individual,and environmental factors are important risk factors for suicidal behavior among teenagers and may contribute to suicide risk through various direct,indirect,or combined pathways.Social-emotional learning is considered a powerful intervention measure for addressing the crisis of adolescent suicide.When deliberately cultivated,fostered,and enhanced,selfawareness,self-management,social awareness,interpersonal skills,and responsible decision-making,as the five core competencies of social-emotional learning,can be used to effectively target various risk factors for adolescent suicide and provide necessary mental and interpersonal support.Among numerous suicide intervention methods,school-based interventions based on social-emotional competence have shown great potential in preventing and addressing suicide risk factors in adolescents.The characteristics of school-based interventions based on social-emotional competence,including their appropriateness,necessity,cost-effectiveness,comprehensiveness,and effectiveness,make these interventions an important means of addressing the crisis of adolescent suicide.To further determine the potential of school-based interventions based on social-emotional competence and better address the issue of adolescent suicide,additional financial support should be provided,the combination of socialemotional learning and other suicide prevention programs within schools should be fully leveraged,and cooperation between schools and families,society,and other environments should be maximized.These efforts should be considered future research directions. 展开更多
关键词 Adolescent suicide Risk factors Social-emotional skills Social and emotional learning SCHOOL prevention
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Unlocking the potential-vitamin D in prostate cancer prevention 被引量:1
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作者 Ayun Cassell Solomane Konneh 《World Journal of Clinical Oncology》 2024年第2期169-174,共6页
Prostate cancer poses a significant health challenge globally,demanding proactive prevention strategies.This editorial explores the emerging role of vitamin D in prostate cancer prevention.While traditionally associat... Prostate cancer poses a significant health challenge globally,demanding proactive prevention strategies.This editorial explores the emerging role of vitamin D in prostate cancer prevention.While traditionally associated with bone health,vitamin D is increasingly recognized for its broader impact on immune function,cellular signaling,and cancer prevention.Epidemiological studies suggest an intriguing link between vitamin D deficiency and elevated prostate cancer risk,particularly in regions with limited sunlight exposure.Mechanistically,vitamin D regulates cellular processes,inhibiting unchecked cancer cell growth and bols-tering immune surveillance.Personalized prevention strategies,considering individual factors,are deemed essential for harnessing the full potential of vitamin D.To unlock this potential,the future calls for robust research,public awareness campaigns,dietary improvements,and vigilant medical guidance.Collaborative efforts are poised to pave the way toward a future where vitamin D stands as a sentinel in prostate cancer prevention,ushering in hope and improved health for men worldwide. 展开更多
关键词 CELL CHOLECALCIFEROL prevention Prostate cancer Vitamin D
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