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3D Printing of Tough Hydrogel Scaffolds with Functional Surface Structures for Tissue Regeneration
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作者 Ke Yao Gaoying Hong +11 位作者 Ximin Yuan Weicheng Kong Pengcheng Xia Yuanrong Li Yuewei Chen Nian Liu Jing He Jue Shi Zihe Hu Yanyan Zhou Zhijian Xie Yong He 《Nano-Micro Letters》 SCIE EI CAS 2025年第2期18-45,共28页
Hydrogel scaffolds have numerous potential applications in the tissue engineering field.However,tough hydrogel scaffolds implanted in vivo are seldom reported because it is difficult to balance biocompatibility and hi... Hydrogel scaffolds have numerous potential applications in the tissue engineering field.However,tough hydrogel scaffolds implanted in vivo are seldom reported because it is difficult to balance biocompatibility and high mechanical properties.Inspired by Chinese ramen,we propose a universal fabricating method(printing-P,training-T,cross-linking-C,PTC&PCT)for tough hydrogel scaffolds to fill this gap.First,3D printing fabricates a hydrogel scaffold with desired structures(P).Then,the scaffold could have extraordinarily high mechanical properties and functional surface structure by cycle mechanical training with salting-out assistance(T).Finally,the training results are fixed by photo-cross-linking processing(C).The tough gelatin hydrogel scaffolds exhibit excellent tensile strength of 6.66 MPa(622-fold untreated)and have excellent biocompatibility.Furthermore,this scaffold possesses functional surface structures from nanometer to micron to millimeter,which can efficiently induce directional cell growth.Interestingly,this strategy can produce bionic human tissue with mechanical properties of 10 kPa-10 MPa by changing the type of salt,and many hydrogels,such as gelatin and silk,could be improved with PTC or PCT strategies.Animal experiments show that this scaffold can effectively promote the new generation of muscle fibers,blood vessels,and nerves within 4 weeks,prompting the rapid regeneration of large-volume muscle loss injuries. 展开更多
关键词 3D printing Tough hydrogel scaffold functional surface structure Tissue regeneration BIOMATERIALS
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3D printing of poly(ethyleneimine)-functionalized Mg-Al mixed metal oxide monoliths for direct air capture of CO_(2)
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作者 Qingyang Shao Zhuozhen Gan +4 位作者 Bingyao Ge Xuyi Liu Chunping Chen Dermot O’Hare Xuancan Zhu 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2024年第9期491-500,共10页
Direct air capture(DAC)of CO_(2)plays an indispensable role in achieving carbon-neutral goals as one of the key negative emission technologies.Since large air flows are required to capture the ultradilute CO_(2)from t... Direct air capture(DAC)of CO_(2)plays an indispensable role in achieving carbon-neutral goals as one of the key negative emission technologies.Since large air flows are required to capture the ultradilute CO_(2)from the air,lab-synthesized adsorbents in powder form may cause unacceptable gas pressure drops and poor heat and mass transfer efficiencies.A structured adsorbent is essential for the implementation of gas-solid contactors for cost-and energy-efficient DAC systems.In this study,efficient adsorbent poly(ethyleneimine)(PEI)-functionalized Mg-Al-CO_(3)layered double hydroxide(LDH)-derived mixed metal oxides(MMOs)are three-dimensional(3D)printed into monoliths for the first time with more than 90%adsorbent loadings.The printing process has been optimized by initially printing the LDH powder into monoliths followed by calcination into MMO monoliths.This structure exhibits a 32.7%higher specific surface area and a 46.1%higher pore volume,as compared to the direct printing of the MMO powder into a monolith.After impregnation of PEI,the monolith demonstrates a large adsorption capacity(1.82 mmol/g)and fast kinetics(0.7 mmol/g/h)using a CO_(2)feed gas at 400 ppm at 25℃,one of the highest values among the shaped DAC adsorbents.Smearing of the amino-polymers during the post-printing process affects the diffusion of CO_(2),resulting in slower adsorption kinetics of pre-impregnation monoliths compared to post-impregnation monoliths.The optimal PEI/MeOH ratio for the post-impregnation solution prevents pores clogging that would affect both adsorption capacity and kinetics. 展开更多
关键词 3D printing Mixed metal oxides Amine functionalization Structured adsorbent Direct air capture
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Emerging trends and prospects of electroconductive bioinks for cell-laden and functional 3D bioprinting 被引量:2
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作者 Harish K.Handral Vaishali P.Natu +3 位作者 Tong Cao Jerry Y.H.Fuh Gopu Sriram Wen F.Lu 《Bio-Design and Manufacturing》 SCIE EI CAS CSCD 2022年第2期396-411,共16页
Introduction 3D bioprinting offers a unique biofabrication platform that allows the generation of functional tissue constructs in a spatially/geometrically controlled and automated manner using a 3 D printer and bioin... Introduction 3D bioprinting offers a unique biofabrication platform that allows the generation of functional tissue constructs in a spatially/geometrically controlled and automated manner using a 3 D printer and bioink.Bioink serves as the carrier medium that provides the ideal physico-mechanical characteristics for printability,shape fidelity,and support;and a biological microenvironment for the living cells prior to,during. 展开更多
关键词 printING functionAL printER
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Effect of copper content on the pyrolysis process of organic components in waste printed circuit boards:Based on experimental and quantum chemical DFT simulations
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作者 Bin Li Biqin Shen +5 位作者 Ran Tao Chenwei Hu Yufeng Wu Haoran Yuan Jing Gu Yong Chen 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2024年第9期202-211,共10页
In recent years,scientists have become increasingly concerned in recycling electronic trash,particularly waste printed circuit boards(WPCBs).Previous research has indicated that the presence of Cu impacts the pyrolysi... In recent years,scientists have become increasingly concerned in recycling electronic trash,particularly waste printed circuit boards(WPCBs).Previous research has indicated that the presence of Cu impacts the pyrolysis of WPCBs.However,there may be errors in the experimental results,as printed circuit boards(PCBs)with copper and those without copper are produced differently.For this experiment,we blended copper powder with PCB nonmetallic resin powder in various ratios to create the samples.The apparent kinetics and pyrolysis properties of four resin powders with varying copper concentrations were compared using nonisothermal thermogravimetric analysis(TG)and thermal pyrolysis-gas chromatography mass spectrometry(Py-GC/MS).From the perspective of kinetics,the apparent activation energy of the resin powder in the pyrolysis reaction shows a rise(0.1<a<0.2)-stable(0.2<a<0.4)-accelerated increase(0.4<a<0.8)-decrease(0.8<a<0.9)process.After adding copper powder,the apparent activation energy changes more obviously when(0.2<a<0.4).In the early stage of the pyrolysis reaction(0.1<a<0.6),the apparent activation energy is reduced,but when a?0.8,it is much higher than that of the resin sample without copper.Additionally,it is discovered using thermogravimetric analysis and Py-GC/MS that copper shortens the temperature range of the primary pyrolysis reaction and prevents the creation of compounds containing bromine.This inhibition will raise the temperature at which compounds containing bromine first form,and it will keep rising as the copper level rises.The majority of the circuit board molecules have lower bond energies when copper is present,according to calculations performed using the Gaussian09 software,which promotes the pyrolysis reaction. 展开更多
关键词 Waste printed circuit boards COPPER PYROLYSIS Kinetic study Density functional theory(DfT)
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Orthodontic treatment combined with 3D printing guide plate implant restoration for edentulism and its influence on mastication and phonic function 被引量:1
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作者 Li-Bo Yan Yu-Chao Zhou +1 位作者 Yang Wang Li-Xin Li 《World Journal of Clinical Cases》 SCIE 2022年第16期5297-5305,共9页
BACKGROUND Dentition defect,a common clinical oral disease developed in humans,not only causes masticatory dysfunction and articulation difficulties but also affects facial appearance and increases the burden on the i... BACKGROUND Dentition defect,a common clinical oral disease developed in humans,not only causes masticatory dysfunction and articulation difficulties but also affects facial appearance and increases the burden on the intestinal tract.Restorative treatment is the primary option for this disease.However,traditional restorations have many drawbacks,such as mismatch with the body,low reliability,and incomplete occlusal function recovery.AIM to analyze the efficacy of orthodontics combined with 3D printing guide plate implant restoration in treating patients with dentition defects and its influence on masticatory and phonic functions.METHODS A prospective study was carried out in 86 patients with dentition defects who received implant prosthesis after orthodontic treatment in our hospital between January 2018 and January 2019.Those patients were divided into a control group and an intervention group with 43 patients in each group using a random number table.The control group received traditional implant restoration,whereas the intervention group received 3D printing guide plate implant restoration.Treatment outcomes,cosmetic appearance,dental function,implant deviation,and quality of life were compared between the two groups.RESULTS The overall response rate in the intervention group was significantly higher than that in the control group(95.35%vs 81.40%,χ^(2)=4.071,P=0.044).The number of cases with neatly trimmed cosmetic appearance(χ^(2)=4.497,P=0.034),complete coverage(χ^(2)=4.170,P=0.041),and normal occlusion(χ^(2)=5.512,P=0.019)in the intervention group was higher than that in the control group.After treatment,mastication,swallowing,and articulation were significantly improved in both groups.Masticatory(t=2.980,P=0.004),swallowing(t=2.199,P=0.031),and phonic functions(t=3.950,P=0.004)were better in the intervention group than those in the control group.The deviation value and the deviation angle(t=5.440,P=0.000)at the top(t=6.320,P=0.000)and middle parts of the implants(t=22.295,P=0.000)in the intervention group were lower than those in the control group after treatment.Functional limitations,psychosocial and physical pain and discomfort,and total scores decreased in both groups.The functional limitation(t=2.379,P=0.020),psychosocial(t=2.420,P=0.000),physical pain and discomfort(t=6.581,P=0.000),and total scores(t=2.140,P=0.035)were lower in the intervention group than those in the control group.CONCLUSION Orthodontic treatment combined with 3D printing guide plate implant restoration can significantly improve the masticatory and phonic functions,quality of life,and psychological health of patients with dentition defects.Therefore,it is highly recommended in clinic application. 展开更多
关键词 Dentition defect ORTHODONTICS 3D printing guide plate implant restoration Masticatory function Phonic function
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Literary Text Translation from Functional Perspective
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作者 李菁菁 《海外英语》 2012年第19期150-152,共3页
Functional linguistics has become the most influential linguistic theory in the field of translation study since the last de cade of 20th century.However,for the complexity of the context,it is uncommon and insufficie... Functional linguistics has become the most influential linguistic theory in the field of translation study since the last de cade of 20th century.However,for the complexity of the context,it is uncommon and insufficient to explore literary texts.Draw ing a general picture of literary text translation from functional perspectives aims to probe into the functional modes of translation. 展开更多
关键词 LITERARY TEXT TRANSLATION functionAL PERSPECTIVE f
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Highly concentrated graphene oxide ink for facile 3D printing of supercapacitors 被引量:6
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作者 Shangwen Ling Wenbin Kang +1 位作者 Shanwen Tao Chuhong Zhang 《Nano Materials Science》 CAS 2019年第2期142-148,共7页
3D printing of functional energy storage devices is receiving escalating attention over the years due to the customizable manufacturing flexibility and imparted high areal and gravimetric energy density of three-dimen... 3D printing of functional energy storage devices is receiving escalating attention over the years due to the customizable manufacturing flexibility and imparted high areal and gravimetric energy density of three-dimensional structured devices, which contribute to the creation of numerous new opportunities for futuristic electronics. Graphene-based inks are ideal elements for the realization of 3D printed energy storage devices if the attractive intrinsic physiochemical properties of graphene could be preserved. However, it is still a great challenge to prepare uniformly dispersed graphene-based materials with desired rheological properties for 3D printing. Here we report a facile strategy for 3D printing of supercapacitors from a highly concentrated graphene oxide (GO) ink. The GO is properly dispersed and the ink fulfills the stringent rheological specifications for 3D printing. The printed GO electrode is functionalized with enhanced structural stability for proper reduction to graphene. The printed supercapacitors deliver the potential to linearly scale up in areal capacitance without jeopardizing the gravimetric capacitance when increasing printed layers. The results hold great promise for the construction of 3D structured energy storage devices that cater to the challenges from next-generation electronics. 展开更多
关键词 3D printING Graphene functional INK SUPERCAPACITOR
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3D printing biomimeticmaterials and structures for biomedical applications 被引量:9
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作者 Yizhen Zhu Dylan Joralmon +5 位作者 Weitong Shan Yiyu Chen Jiahui Rong Hanyu Zhao Siqi Xiao Xiangjia Li 《Bio-Design and Manufacturing》 SCIE EI CSCD 2021年第2期405-428,共24页
Over millions of years of evolution,nature has created organisms with overwhelming performances due to their unique materials and structures,providing us with valuable inspirations for the development of next-generati... Over millions of years of evolution,nature has created organisms with overwhelming performances due to their unique materials and structures,providing us with valuable inspirations for the development of next-generation biomedical devices.As a promising new technology,3D printing enables the fabrication of multiscale,multi-material,and multi-functional threedimensional(3D)biomimetic materials and structures with high precision and great flexibility.The manufacturing challenges of biomedical devices with advanced biomimetic materials and structures for various applications were overcome with the flourishing development of 3D printing technologies.In this paper,the state-of-the-art additive manufacturing of biomimetic materials and structures in the field of biomedical engineering were overviewed.Various kinds of biomedical applications,including implants,lab-on-chip,medicine,microvascular network,and artificial organs and tissues,were respectively discussed.The technical challenges and limitations of biomimetic additive manufacturing in biomedical applications were further investigated,and the potential solutions and intriguing future technological developments of biomimetic 3D printing of biomedical devices were highlighted. 展开更多
关键词 3D printing BIOprintING Biomimetic material functional structures Biomedical applications
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Bacillus licheniformis PF9 improves barrier function and alleviates inflammatory responses against enterotoxigenic Escherichia coli F4 infection in the porcine intestinal epithelial cells 被引量:5
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作者 Qiao Li Linyan Li +4 位作者 Yanhong Chen Changning Yu Paula Azevedo Joshua Gong Chengbo Yang 《Journal of Animal Science and Biotechnology》 SCIE CAS CSCD 2022年第5期1413-1427,共15页
Background:Enterotoxigenic Escherichia coli(ETEC)F4 commonly colonizes the small intestine and releases enterotoxins that impair the intestinal barrier function and trigger inflammatory responses.Although Bacillus lic... Background:Enterotoxigenic Escherichia coli(ETEC)F4 commonly colonizes the small intestine and releases enterotoxins that impair the intestinal barrier function and trigger inflammatory responses.Although Bacillus licheniformis(B.licheniformis)has been reported to enhance intestinal health,it remains to be seen whether there is a functional role of B.licheniformis in intestinal inflammatory response in intestinal porcine epithelial cell line(IPEC-J2)when stimulated with ETEC F4.Methods:In the present study,the effects of B.licheniformis PF9 on the release of pro-inflammation cytokines,cell integrity and nuclear factor-κB(NF-κB)activation were evaluated in ETEC F4-induced IPEC-J2 cells.Results:B.licheniformis PF9 treatment was capable of remarkably attenuating the expression levels of inflammation cytokines tumor necrosis factor-α(TNF-α),interleukin(IL)-8,and IL-6 during ETEC F4 infection.Furthermore,the gene expression of Toll-like receptor 4(TLR4)-mediated upstream related genes of NF-κB signaling pathway has been significantly inhibited.These changes were accompanied by significantly decreased phosphorylation of p65 NF-κB during ETEC F4 infection with B.licheniformis PF9 treatment.The immunofluorescence and western blotting analysis revealed that B.licheniformis PF9 increased the expression levels of zona occludens 1(ZO-1)and occludin(OCLN)in ETEC F4-infected IPEC-J2 cells.Meanwhile,the B.licheniformis PF9 could alleviate the injury of epithelial barrier function assessed by the trans-epithelial electrical resistance(TEER)and cell permeability assay.Interestingly,B.licheniformis PF9 protect IPEC-J2 cells against ETEC F4 infection by decreasing the gene expressions of virulence-related factors(including luxS,estA,estB,and elt)in ETEC F4.Conclusions:Collectively,our results suggest that B.licheniformis PF9 might reduce inflammation-related cytokines through blocking the NF-κB signaling pathways.Besides,B.licheniformis PF9 displayed a significant role in the enhancement of IPEC-J2 cell integrity. 展开更多
关键词 Bacillus licheniformis Pf9 Barrier function ETEC f4 Inflammatory response IPEC-J2
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Recent advances in meniscus-on-demand three-dimensional micro-and nano-printing for electronics and photonics 被引量:2
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作者 Shiqi Hu Xiao Huan +3 位作者 Yu Liu Sixi Cao Zhuoran Wang Ji Tae Kim 《International Journal of Extreme Manufacturing》 SCIE EI CAS CSCD 2023年第3期302-317,共16页
The continual demand for modern optoelectronics with a high integration degree and customized functions has increased requirements for nanofabrication methods with high resolution,freeform,and mask-free.Meniscus-on-de... The continual demand for modern optoelectronics with a high integration degree and customized functions has increased requirements for nanofabrication methods with high resolution,freeform,and mask-free.Meniscus-on-demand three-dimensional(3D)printing is a high-resolution additive manufacturing technique that exploits the ink meniscus formed on a printer nozzle and is suitable for the fabrication of micro/nanoscale 3D architectures.This method can be used for solution-processed 3D patterning of materials at a resolution of up to100 nm,which provides an excellent platform for fundamental scientific studies and various practical applications.This review presents recent advances in meniscus-on-demand 3D printing,together with historical perspectives and theoretical background on meniscus formation and stability.Moreover,this review highlights the capabilities of meniscus-on-demand 3D printing in terms of printable materials and potential areas of application,such as electronics and photonics. 展开更多
关键词 3D printing ink meniscus functional materials ELECTRONICS PHOTONICS
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Advances in 3D printing scaffolds for peripheral nerve and spinal cord injury repair 被引量:3
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作者 Juqing Song Baiheng Lv +2 位作者 Wencong Chen Peng Ding Yong He 《International Journal of Extreme Manufacturing》 SCIE EI CAS CSCD 2023年第3期264-300,共37页
Because of the complex nerve anatomy and limited regeneration ability of natural tissue,the current treatment effect for long-distance peripheral nerve regeneration and spinal cord injury(SCI)repair is not satisfactor... Because of the complex nerve anatomy and limited regeneration ability of natural tissue,the current treatment effect for long-distance peripheral nerve regeneration and spinal cord injury(SCI)repair is not satisfactory.As an alternative method,tissue engineering is a promising method to regenerate peripheral nerve and spinal cord,and can provide structures and functions similar to natural tissues through scaffold materials and seed cells.Recently,the rapid development of 3D printing technology enables researchers to create novel 3D constructs with sophisticated structures and diverse functions to achieve high bionics of structures and functions.In this review,we first outlined the anatomy of peripheral nerve and spinal cord,as well as the current treatment strategies for the peripheral nerve injury and SCI in clinical.After that,the design considerations of peripheral nerve and spinal cord tissue engineering were discussed,and various 3D printing technologies applicable to neural tissue engineering were elaborated,including inkjet,extrusion-based,stereolithography,projection-based,and emerging printing technologies.Finally,we focused on the application of 3D printing technology in peripheral nerve regeneration and spinal cord repair,as well as the challenges and prospects in this research field. 展开更多
关键词 peripheral nerve regeneration spinal cord repair 3D printing construct bionic structure bionic function
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Low-temperature 3D-printed collagen/chitosan scaffolds loaded with exosomes derived from neural stem cells pretreated with insulin growth factor-1 enhance neural regeneration after traumatic brain injury 被引量:4
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作者 Xiao-Yin Liu Yin-He Feng +7 位作者 Qing-Bo Feng Jian-Yong Zhang Lin Zhong Peng Liu Shan Wang Yan-Ruo Huang Xu-Yi Chen Liang-Xue Zhou 《Neural Regeneration Research》 SCIE CAS CSCD 2023年第9期1990-1998,共9页
There are various clinical treatments for traumatic brain injury,including surgery,drug therapy,and rehabilitation therapy;howeve r,the therapeutic effects are limited.Scaffolds combined with exosomes represent a prom... There are various clinical treatments for traumatic brain injury,including surgery,drug therapy,and rehabilitation therapy;howeve r,the therapeutic effects are limited.Scaffolds combined with exosomes represent a promising but challenging method for improving the repair of traumatic brain injury.In this study,we determined the ability of a novel 3D-printed collagen/chitosan scaffold loaded with exosomes derived from neural stem cells pretreated with insulin-like growth factor-1(3D-CC-INEXOS) to improve traumatic brain injury repair and functional recove ry after traumatic brain injury in rats.Composite scaffolds comprising collagen,chitosan,and exosomes derived from neural stem cells pretreated with insulin-like growth fa ctor-1(INEXOS) continuously released exosomes for 2weeks.Transplantation of 3D-CC-INExos scaffolds significantly improved motor and cognitive functions in a rat traumatic brain injury model,as assessed by the Morris water maze test and modified neurological seve rity scores.In addition,immunofluorescence staining and transmission electron microscopy showed that3D-CC-INExos implantation significantly improved the recove ry of damaged nerve tissue in the injured area.In conclusion,this study suggests that transplanted3D-CC-INExos scaffolds might provide a potential strategy for the treatment of traumatic brain injury and lay a solid foundation for clinical translation. 展开更多
关键词 3D printing ANGIOGENESIS chitosan COLLAGEN EXOSOMES functional recovery insulin-like growth factor-1 neural regeneration neural stem cells traumatic brain injury
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MiR-19a-3p regulates the Forkhead box F2-mediated Wnt/β-catenin signaling pathway and affects the biological functions of colorectal cancer cells 被引量:8
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作者 Fu-Bing Yu Juan Sheng +3 位作者 Jia-Man Yu Jing-Hua Liu Xiang-Xin Qin Bo Mou 《World Journal of Gastroenterology》 SCIE CAS 2020年第6期627-644,共18页
BACKGROUND Colorectal cancer(CRC)is one of the most common malignancies worldwide.AIM To explore the expression of microRNA miR-19a-3p and Forkhead box F2(FOXF2)in patients with CRC and the relevant mechanisms.METHODS... BACKGROUND Colorectal cancer(CRC)is one of the most common malignancies worldwide.AIM To explore the expression of microRNA miR-19a-3p and Forkhead box F2(FOXF2)in patients with CRC and the relevant mechanisms.METHODS Sixty-two CRC patients admitted to the hospital were enrolled into the study group,and sixty healthy people from the same period were assigned to the control group.Elbow venous blood was sampled from the patients and healthy individuals,and blood serum was saved for later analysis.MiR-19a-3p mimics,miR-19a-3p inhibitor,miR-negative control,small interfering-FOXF2,and short hairpin-FOXF2 were transfected into HT29 and HCT116 cells.Then quantitative polymerase chain reaction was performed to quantify the expression of miR-19a-3p and FOXF2 in HT29 and HCT116 cells,and western blot(WB)analysis was conducted to evaluate the levels of FOXF2,glycogen synthase kinase 3 beta(GSK-3β),phosphorylated GSK-3β(p-GSK-3β),β-catenin,p-β-catenin,α-catenin,Ncadherin,E-cadherin,and vimentin.The MTT,Transwell,and wound healing assays were applied to analyze cell proliferation,invasion,and migration,respectively,and the dual luciferase reporter assay was used to determine the correlation of miR-19a-3p with FOXF2.RESULTS The patients showed high serum levels of miR-19a-3p and low levels of FOXF2,and the area under the curves of miR-19a-3p and FOXF2 were larger than 0.8.MiR-19a-3p and FOXF2 were related to sex,tumor size,age,tumor-nodemetastasis staging,lymph node metastasis,and differentiation of CRC patients.Silencing of miR-19a-3p and overexpression of FOXF2 suppressed the epithelialmesenchymal transition,invasion,migration,and proliferation of cells.WB analysis revealed that silencing of miR-19a-3p and FOXF2 overexpression significantly suppressed the expression of p-GSK-3β,β-catenin,N-cadherin,and vimentin;and increased the levels of GSK-3β,p-β-catenin,α-catenin,and Ecadherin.The dual luciferase reporter assay confirmed that there was a targeted correlation of miR-19a-3p with FOXF2.In addition,a rescue experiment revealed that there were no differences in cell proliferation,invasion,and migration in HT29 and HCT116 cells co-transfected with miR-19a-3p-mimics+sh-FOXF2 and miR-19a-3p-inhibitor+si-FOXF2 compared to the miR-negative control group.CONCLUSION Inhibiting miR-19a-3p expression can upregulate the FOXF2-mediated Wnt/β-catenin signaling pathway,thereby affecting the epithelial-mesenchymal transition,proliferation,invasion,and migration of cells.Thus,miR-19a-3p is likely to be a therapeutic target in CRC. 展开更多
关键词 MiR-19a-3p forkhead box f2 Wnt/β-catenin signaling pathway Biological function Colorectal cancer Western blot
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F-53B胁迫下污水厌氧处理系统及微生物群落的响应 被引量:2
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作者 郭雨婷 刘亚军 +5 位作者 邓觅 涂勋 吴虎彬 李昆 李荣富 吴永明 《中国环境科学》 EI CAS CSCD 北大核心 2024年第2期721-729,共9页
通过构建厌氧反应体系,评估低浓度(1mg/L)和高浓度(10mg/L)氯化多氟醚磺酸盐(F-53B)胁迫下,厌氧处理系统出水水质、污泥性状和细菌群落的响应特征.结果表明,在F-53B的胁迫下,COD、氮(TN、NH_(4)^(+)-N)和磷(TP、PO_(4)^(3-)-P)在出水中... 通过构建厌氧反应体系,评估低浓度(1mg/L)和高浓度(10mg/L)氯化多氟醚磺酸盐(F-53B)胁迫下,厌氧处理系统出水水质、污泥性状和细菌群落的响应特征.结果表明,在F-53B的胁迫下,COD、氮(TN、NH_(4)^(+)-N)和磷(TP、PO_(4)^(3-)-P)在出水中的含量会升高,而污泥相对生物量(MLVSS/MLSS)则出现下降,且F-53B的浓度越高影响越大.高通量测序分析发现,相较于对照组(0mg/L F-53B),仅高浓度F-53B胁迫下细菌群落的多样性(ACE、Chao1和PD指数)出现了显著下降.同时,研究还发现,随着高浓度F-53B暴露时间的延长,厚壁菌门的相对丰度逐渐增大,而变形菌门、拟杆菌门和硝化螺旋菌门的相对丰度逐渐降低.此外,基于FAPROTAX功能预测分析发现,F-53B胁迫下微生物表现出更低的氮(N)代谢潜力和更高的化能异养和发酵能力.冗余分析(RDA)表明,厚壁菌门主要受F-53B的正向影响,并与TN和NH_(4)^(+)-N呈正相关;而变形菌门受F-53B的负向影响,并与COD、TP和PO_(4)^(3-)-P呈正相关.揭示了新型氟化物—F-53B对污水厌氧处理系统的胁迫机制. 展开更多
关键词 氯化多氟醚磺酸盐(f-53B) 污水厌氧处理 微生物群落 功能预测
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A MAXIMAL FUNCTION CHARACTERIZATION 0F HARDY SPACES ON SPACES OF HOMOGENEOUS TYPE 被引量:6
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作者 Li Wenming Zhongshan University, China 《Analysis in Theory and Applications》 1998年第2期12-27,共16页
A new maximal function is introduced in the dual spaces of test function spaces on spaces of homogeneous type. Using this maximal function, we get new characterization of atomic H^p spaces.
关键词 A MAXIMAL function CHARACTERIZATION 0f HARDY SPACES ON SPACES Of HOMOGENEOUS TYPE APPI 尸气
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Density functional calculations on the geometric structure and properties of the 3d transition metal atom doped endohedral fullerene M@C_(20)F_(20)(M=Sc-Ni) 被引量:1
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作者 唐春梅 朱卫华 邓开明 《Chinese Physics B》 SCIE EI CAS CSCD 2010年第3期302-305,共4页
This paper uses the generalised gradient approximation based on density functional theory to analyse the geometric structure and properties of the 3d transition metal atom doped endohedral fullerene M@C20F20 (M = Sc... This paper uses the generalised gradient approximation based on density functional theory to analyse the geometric structure and properties of the 3d transition metal atom doped endohedral fullerene M@C20F20 (M = Sc-Ni). The geometric optimization shows that the cage centre is the most stable position for M, forming the structure named as M@C20F20-4. The inclusion energy, zero-point energy, and energy gap calculations tell us that Ni@C20F20-4 should be thermodynamically and kinetically stablest. M@C20F20-4 (M = Sc-Co) possesses high magnetic moments varied from 1 to 6 μB, while Ni@C20F20-4 is nonmagnetic. The Ni-C bond in Ni@C20F20-4 contains both the covalent and ionic characters. 展开更多
关键词 M@C20f20 transition metal magnetic property density functional
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Molecule functionalization to facilitate electrocatalytic oxygen reduction on graphdiyne 被引量:1
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作者 Huiying Yao Yasong Zhao +6 位作者 Nailiang Yang Wei Hao Hu Zhao Shuzhou Li Jia Zhu Lin Shen Weihai Fang 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2022年第2期141-148,共8页
Chemical doping is verified to be a promising strategy to regulate local electron distribution and further promote the poor intrinsic catalytic activity of graphdiyne.However,the current doping approach still faces pr... Chemical doping is verified to be a promising strategy to regulate local electron distribution and further promote the poor intrinsic catalytic activity of graphdiyne.However,the current doping approach still faces problems such as precise doping for creating active sites and the destruction of graphdiyne skeleton calling for high temperature.Here,we achieved charge redistribution on graphdiyne surface through molecule functionalization.A p-type molecule–F4 TCNQ(2,3,5,6-tetrafluoro-7,7,8,8-tetracyanoquinodime thane)was introduced and the site-defined functionalization was accomplished.Theoretical calculations showed that the charge transfer ability is improved and graphdiyne becomes positively charged.The oxygen reduction electrocatalysis was conducted as a proof of principle,where the electronic states of sp hybridized C active site was tuned toward favorable reaction intermediates’adsorption.Such work from both theoretical prediction and experimental validation,found that molecule functionalization is effective to promote the electrocatalytic oxygen reduction,which creates new possibilities for graphdiyne’s applications in different electrochemical reactions. 展开更多
关键词 Graphdiyne f4TCNQ Density functional calculations Electronic structure Oxygen reduction reaction
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GRADIENT ESTIMATES FOR POSITIVE SMOOTH f-HARMONIC FUNCTIONS 被引量:3
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作者 陈立 陈文艺 《Acta Mathematica Scientia》 SCIE CSCD 2010年第5期1614-1618,共5页
For Riemannian manifolds with a measure, we study the gradient estimates for positive smooth f-harmonic functions when the ∞-Bakry-Emery Ricci tensor and Ricci tensor are bounded from below, generalizing the classica... For Riemannian manifolds with a measure, we study the gradient estimates for positive smooth f-harmonic functions when the ∞-Bakry-Emery Ricci tensor and Ricci tensor are bounded from below, generalizing the classical ones of Yau (i.e., when : is constant). 展开更多
关键词 gradient estimate f-harmonic function Bakry-Emery Ricci tensor
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动力系统中F-传递性与F-混合性的一个注记
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作者 姜文雅 张思汇 刘杰 《上海理工大学学报》 CAS CSCD 北大核心 2024年第4期427-430,共4页
对一维动力系统的混合性及传递性进行了一般性讨论。设(I,f)是一个拓扑动力系统(简称动力系统或系统),其中I为紧致度量空间(度量为d),f:X→X是连续映射。基于Furstenberg族,研究了一维动力系统(I,f)和它的泛函包络系统(L^(1)(I,I),H_(f)... 对一维动力系统的混合性及传递性进行了一般性讨论。设(I,f)是一个拓扑动力系统(简称动力系统或系统),其中I为紧致度量空间(度量为d),f:X→X是连续映射。基于Furstenberg族,研究了一维动力系统(I,f)和它的泛函包络系统(L^(1)(I,I),H_(f))的一些性质,在前人研究的混合性和传递性的基础上,引进了F–混合与F–传递的概念,并证明了如果(I,f)是F–混合的,则(L^(1)(I,I),H_(f))是F–传递的。 展开更多
关键词 f–传递 f–混合 泛函包络
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C语言中自加运算在printf()函数中使用情况分析
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作者 智西湖 《洛阳大学学报》 1995年第4期34-37,共4页
对C语言printf()函数中自加运算使用情况进行了分析,并给出了自加运算作为参数形式出现时,C语言对其进行处理的规律.
关键词 C语言 printf()函数 自加运算规律 输出函数
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