A refined reciprocating probe system was installed on the midplane of HL-2A tokamak. The system is developed in collaboration with the Institute of Scientific Instrument, Chinese Academy of Science in Shenyang.The sys...A refined reciprocating probe system was installed on the midplane of HL-2A tokamak. The system is developed in collaboration with the Institute of Scientific Instrument, Chinese Academy of Science in Shenyang.The system has been used to measure edge density, temperature, potential and their fluctuation profiles with 8 cm scan from scrapeoff layer to plasma boundary. The velocity of the reciprocating stroke is designed by 1 m ·s^-1.展开更多
A fast radial scanning probe system was constructed for the Keda Torus eXperiment(KTX)to measure the profiles of boundary plasma parameters such as floating potential,electron density,temperature,transport fluxes,etc....A fast radial scanning probe system was constructed for the Keda Torus eXperiment(KTX)to measure the profiles of boundary plasma parameters such as floating potential,electron density,temperature,transport fluxes,etc.The scanning probe system is driven by slow and fast motion mechanisms,corresponding to the stand-by movement of a stepping motor and the fast scanning movement of a high-torque servo-motor,respectively.In fast scanning,the scanner drives the probe radially up to 20 cm at a maximum velocity of 4.0 m s-1.A noncontact magnetic grating ruler with a high spatial resolution of 5μm is used for the displacement measurement.New scanning probe can reach the center of plasmas rapidly.The comparison of plasma floating potential profiles obtained by a fixed radial rake probe and the single scanning probe suggests that the high-speed scanning probe system is reliable for measuring edge plasma parameter profiles on the KTX device.展开更多
A multi-voltage probe array system is designed to measure the coupling resistance of an ion cyclotron resonance frequency antenna. In the process of the antenna coupling resistance data extraction, the minimization al...A multi-voltage probe array system is designed to measure the coupling resistance of an ion cyclotron resonance frequency antenna. In the process of the antenna coupling resistance data extraction, the minimization algorithm, the original Levenberg–Marquardt algorithm, is replaced by the Broyden–Fletcher–Goldfarb–Shanno algorithm to achieve more stable and accurate results. Moreover, a simple model of the multi-voltage probe array was applied to simulate the performance of the Kalman filter, and to optimize the distance and position of the probes and probe number to mitigate the influence of the system noise on the rebuilt results. During the EAST experiment in 2019, a four-voltage probe array was applied to measure the coupling resistance of line 6 during high confined mode discharge. The measurement results by the multivoltage probe array system and the voltage/current probe pair show a good agreement.展开更多
In order to obtain creditable data an applicable method to optimize parameters of the Langmuir probes and circuits in a stationary laboratory device is investigated and an experimental criterion of the probe dimension...In order to obtain creditable data an applicable method to optimize parameters of the Langmuir probes and circuits in a stationary laboratory device is investigated and an experimental criterion of the probe dimension is developed. To obtain the electron temperature and density the Electron Energy Distribution Function (EEDF) approach with less computing time and more accurate results is applied, instead of the conventional slope approach. Moreover the influence of the vessel wall materials on the plasma density is discussed briefly, indicating that the dielectric wall is helpful to enhancing the electron density.展开更多
A newly designed divertor Langmuir probe diagnostic system has been installed in a rare closed divertor of the HL-2A tokamak and steadily operated for the study of divertor physics involved edge-localized mode mitigat...A newly designed divertor Langmuir probe diagnostic system has been installed in a rare closed divertor of the HL-2A tokamak and steadily operated for the study of divertor physics involved edge-localized mode mitigation,detachment and redistribution of heat flux,etc.Two sets of probe arrays including 274 probe tips were placed at two ports(approximately 180°separated toroidally),and the spatial and temporal resolutions of this measurement system could reach6 mm and 1μs,respectively.A novel design of the ceramic isolation ring can ensure reliable electrical insulation property between the graphite tip and the copper substrate plate where plasma impurities and the dust are deposited into the gaps for a long experimental time.Meanwhile,the condition monitoring and mode conversion between single and triple probe of the probe system could be conveniently implemented via a remote-control station.The preliminary experimental result shows that the divertor Langmuir probe system is capable of measuring the high spatiotemporal parameters involved the plasma density,electron temperature,particle flux as well as heat flux during the ELMy H-mode discharges.展开更多
Conventional conductivity methods for measuring the void fraction in gas-liquid multiphase systems are typically affected by accuracy problems due to the presence of fluid flow and salinity.This study presents a novel...Conventional conductivity methods for measuring the void fraction in gas-liquid multiphase systems are typically affected by accuracy problems due to the presence of fluid flow and salinity.This study presents a novel approach for determining the void fraction based on a reciprocating dynamic conductivity probe used to measure the liquid film thickness under forced annular-flow conditions.The measurement system comprises a cyclone,a conductivity probe,a probe reciprocating device,and a data acquisition and processing system.This method ensures that the flow pattern is adjusted to a forced annular flow,thereby minimizing the influence of complex and variable gas-liquid flow patterns on the measurement results;Moreover,it determines the liquid film thickness solely according to circuit connectivity rather than specific conductivity values,thereby mitigating the impact of salinity.The reliability of the measurement system is demonstrated through laboratory experiments.The experimental results indicate that,in a range of gas phase superficial velocities 5–20 m/s and liquid phase superficial velocities 0.079–0.48 m/s,the maximum measurement deviation for the void fraction is 4.23%.展开更多
Liquid-liquid mixing,including homogeneous and heterogeneous mixing,widely exists in the chemical industry.How to quantitatively characterize the mixing performance is important for reactor assessment and development....Liquid-liquid mixing,including homogeneous and heterogeneous mixing,widely exists in the chemical industry.How to quantitatively characterize the mixing performance is important for reactor assessment and development.As a convenient and direct method for mixing characterization,the chemical probe method uses some special test reactions to characterize the mixing results.Here,the working principle and selection requirements of this method are introduced,and some common chemical probe systems for homogeneous and heterogeneous mixing processes are reviewed.The characteristics and applications of these systems are illustrated.Finally,the development of the new system is proposed.展开更多
The novel SoftwareDefined Networking(SDN)architecture potentially resolves specific challenges arising from rapid internet growth of and the static nature of conventional networks to manage organizational business req...The novel SoftwareDefined Networking(SDN)architecture potentially resolves specific challenges arising from rapid internet growth of and the static nature of conventional networks to manage organizational business requirements with distinctive features.Nevertheless,such benefits lead to a more adverse environment entailing network breakdown,systems paralysis,and online banking fraudulence and robbery.As one of the most common and dangerous threats in SDN,probe attack occurs when the attacker scans SDN devices to collect the necessary knowledge on system susceptibilities,which is thenmanipulated to undermine the entire system.Precision,high performance,and real-time systems prove pivotal in successful goal attainment through feature selection to minimize computation time,optimize prediction performance,and provide a holistic understanding of machine learning data.As the extension of astute machine learning algorithms into an Intrusion Detection System(IDS)through SDN has garnered much scholarly attention within the past decade,this study recommended an effective IDS under the Grey-wolf optimizer(GWO)and Light Gradient Boosting Machine(Light-GBM)classifier for probe attack identification.The InSDN dataset was employed to train and test the proposed IDS,which is deemed to be a novel benchmarking dataset in SDN.The proposed IDS assessment demonstrated an optimized performance against that of peer IDSs in probe attack detection within SDN.The results revealed that the proposed IDS outperforms the state-of-the-art IDSs,as it achieved 99.8%accuracy,99.7%recall,99.99%precision,and 99.8%F-measure.展开更多
A flexible or planar eddy current probe with a differential structure can suppress the lift-off noise during the inspection of defects.However,the extent of the lift-off effect on differential probes,including differe...A flexible or planar eddy current probe with a differential structure can suppress the lift-off noise during the inspection of defects.However,the extent of the lift-off effect on differential probes,including different coil structures,varies.In this study,two planar eddy current probes with differential pickup structures and the same size,Koch and circular probes,were used to compare lift-off effects.The eddy current distributions of the probes perturbed by 0°and 90°cracks were obtained by finite element analysis.The analysis results show that the 90°crack can impede the eddy current induced by the Koch probe even further at relatively low lift-off distance.The peak-to-peak values of the signal output from the two probes were compared at different lift-off distances using finite element analysis and experimental methods.In addition,the effects of different frequencies on the lift-off were studied experimentally.The results show that the signal peak-to-peak value of the Koch probe for the inspection of cracks in 90°orientation is larger than that of the circular probe when the lift-off distance is smaller than 1.2 mm.In addition,the influence of the lift-off distance on the peak-to-peak signal value of the two probes was studied via normalization.This indicates that the influence becomes more evident with an increase in excitation frequency.This research discloses the lift-off effect of differential planar eddy current probes with different coil shapes and proves the detection merit of the Koch probe for 90°cracks at low lift-off distances.展开更多
Rheumatoid arthritis(RA)is a systemic autoimmune disease that is primarily manifested as synovitis and polyarticular opacity and typically leads to serious joint damage and irreversible disability,thus adversely affec...Rheumatoid arthritis(RA)is a systemic autoimmune disease that is primarily manifested as synovitis and polyarticular opacity and typically leads to serious joint damage and irreversible disability,thus adversely affecting locomotion ability and life quality.Consequently,good prognosis heavily relies on the early diagnosis and effective therapeutic monitoring of RA.Activatable fluorescent probes play vital roles in the detection and imaging of biomarkers for disease diagnosis and in vivo imaging.Herein,we review the fluorescent probes developed for the detection and imaging of RA biomarkers,namely reactive oxygen/nitrogen species(hypochlorous acid,peroxynitrite,hydroxyl radical,nitroxyl),pH,and cysteine,and address the related challenges and prospects to inspire the design of novel fluorescent probes and the improvement of their performance in RA studies.展开更多
Feline calicivirus(FCV)was a highly prevalent RNA virus causing upper respiratory tract infections in cats through the mouth and nose around the world,result in the death of cats especially under 1 year old with upper...Feline calicivirus(FCV)was a highly prevalent RNA virus causing upper respiratory tract infections in cats through the mouth and nose around the world,result in the death of cats especially under 1 year old with upper respiratory tract disease(URTD)and virulent systemic disease(FCV-VSD)[1].Infected cats usually presented with mouth ulcers,salivation and gingivitis-stomatitis.Furthermore,both recovered cats and asymptomatic carriers can still carry and spread the FCV virus for extended periods of time,contributing to the potential for outbreak.This presented a significant threat to the health and lives of cats,and rare wildlife and took a heavy financial loss on the pet industry,making the prevention and control of the virus difficult.Hence,rapid identification of FCV in clinical samples was necessary to prevent the spread of FCV and avoid financial loss.展开更多
Uniaxial strain is a powerful tuning parameter that can control symmetry and anisotropic electronic properties in iron-based superconductors.However,accurately characterizing anisotropic strain can be challenging and ...Uniaxial strain is a powerful tuning parameter that can control symmetry and anisotropic electronic properties in iron-based superconductors.However,accurately characterizing anisotropic strain can be challenging and complex.Here,we utilize a cryogenic optical system equipped with a high-spatial-resolution microscope to characterize surface strains in iron-based superconductors using the digital image correlation method.Compared with other methods such as high-resolution x-ray diffraction,strain gauge,and capacitive sensor,digital image correlation offers a non-contact full-field measurement approach,acting as an optical virtual strain gauge that provides high spatial resolution.The results measured on detwinned BaFe_(2)As_(2)are quantitatively consistent with the distortion measured by x-ray diffraction and neutron Larmor diffraction.These findings highlight the potential of cryogenic digital image correlation as an effective and accessible tool for probing the isotropic and anisotropic strains,facilitating applications of uniaxial strain tuning in research of quantum materials.展开更多
A novel emissive probe consisting of an oxide cathode coating is developed to achieve a low operating temperature and long service life.The properties of the novel emissive probe are investigated in detail,in comparis...A novel emissive probe consisting of an oxide cathode coating is developed to achieve a low operating temperature and long service life.The properties of the novel emissive probe are investigated in detail,in comparison with a traditional tungsten emissive probe,including the operating temperature,the electron emission capability and the plasma potential measurement.Studies of the operating temperature and electron emission capability show that the tungsten emissive probe usually works at a temperature of 1800 K-2200 K while the oxide cathode emissive probe can function at about 1200 K-1400 K.In addition,plasma potential measurements using the oxide cathode emissive probe with different techniques have been accomplished in microwave electron cyclotron resonance plasmas with different discharge powers.It is found that a reliable plasma potential can be obtained using the improved inflection point method and the hot probe with zero emission limit method,while the floating point method is invalid for the oxide cathode emissive probe.展开更多
An integrated quantum probe for magnetic field imaging is proposed,where the nitrogen–vacancy(NV)center fixed at the fiber tip is located on the periphery of flexible ring resonator.Using flexible polyimide(PI)as the...An integrated quantum probe for magnetic field imaging is proposed,where the nitrogen–vacancy(NV)center fixed at the fiber tip is located on the periphery of flexible ring resonator.Using flexible polyimide(PI)as the substrate medium,we design a circular microstrip antenna,which can achieve a bandwidth of 140 MHz at Zeeman splitting frequency of 2.87 GHz,specifically suitable for NV center experiments.Subsequently,this antenna is seamlessly fixed at a three-dimensional-printed cylindrical support,allowing the optical fiber tip to extend out of a dedicated aperture.To mitigate errors originating from processing,precise tuning within a narrow range can be achieved by adjusting the conformal amplitude.Finally,we image the microwave magnetic field around the integrated probe with high resolution,and determine the suitable area for placing the fiber tip(SAP).展开更多
Implanted neural probes can detect weak discharges of neurons in the brain by piercing soft brain tissue,thus as important tools for brain science research,as well as diagnosis and treatment of brain diseases.However,...Implanted neural probes can detect weak discharges of neurons in the brain by piercing soft brain tissue,thus as important tools for brain science research,as well as diagnosis and treatment of brain diseases.However,the rigid neural probes,such as Utah arrays,Michigan probes,and metal microfilament electrodes,are mechanically unmatched with brain tissue and are prone to rejection and glial scarring after implantation,which leads to a significant degradation in the signal quality with the implantation time.In recent years,flexible neural electrodes are rapidly developed with less damage to biological tissues,excellent biocompatibility,and mechanical compliance to alleviate scarring.Among them,the mechanical modeling is important for the optimization of the structure and the implantation process.In this review,the theoretical calculation of the flexible neural probes is firstly summarized with the processes of buckling,insertion,and relative interaction with soft brain tissue for flexible probes from outside to inside.Then,the corresponding mechanical simulation methods are organized considering multiple impact factors to realize minimally invasive implantation.Finally,the technical difficulties and future trends of mechanical modeling are discussed for the next-generation flexible neural probes,which is critical to realize low-invasiveness and long-term coexistence in vivo.展开更多
Lithium hexafluorophosphate(LiPF_(6)),the most commonly used lithium battery electrolyte salt,is vulnerable to heat and humidity.Quantitative and qualitative determination the variation of LiPF_(6)have always relied o...Lithium hexafluorophosphate(LiPF_(6)),the most commonly used lithium battery electrolyte salt,is vulnerable to heat and humidity.Quantitative and qualitative determination the variation of LiPF_(6)have always relied on advanced equipment.Herein,we develop a fast,convenient,high-selective fluorescence detection method based on metal-organic cages(MOC),whose emission is enhanced by nearly 20 times in the presence of LiPF_(6)with good stability and photobleaching resistance.The fluorescent probe can also detect moisture in battery electrolyte.We propose and verify that the luminescence enhancement is due to the presence of hydrogen bond-induced enhanced emission effect in cages.Fluorescent excitation-emission matrix spectra and variable-temperature nuclear magnetic resonance spectroscopy are employed to clarify the role of hydrogen bonds in guest-loaded cages.Density functional theory(DFT)calculation is applied to simulate the structure of host-guest complexes and estimate the adsorption energy involved in the system.The precisely matched lock-and-key model paves a new way for designing and fabricating novel host structures,enabling specific recognition of other target compounds.展开更多
The high-resolution and nondestructive co-reference measurement of the inner and outer threedimensional(3D)surface profiles of laser fusion targets is difficult to achieve.In this study,we propose a laser differential...The high-resolution and nondestructive co-reference measurement of the inner and outer threedimensional(3D)surface profiles of laser fusion targets is difficult to achieve.In this study,we propose a laser differential confocal(LDC)–atomic force probe(AFP)method to measure the inner and outer 3D surface profiles of laser fusion targets at a high resolution.This method utilizes the LDC method to detect the deflection of the AFP and exploits the high spatial resolution of the AFP to enhance the spatial resolution of the outer profile measurement.Nondestructive and co-reference measurements of the inner profile of a target were achieved using the tomographic characteristics of the LDC method.Furthermore,by combining multiple repositionings of the target using a horizontal slewing shaft,the inner and outer 3D surface profiles of the target were obtained,along with a power spectrum assessment of the entire surface.The experimental results revealed that the respective axial and lateral resolutions of the outer profile measurement were 0.5 and 1.3 nm,while the respective axial and lateral resolutions of the inner profile measurement were 2.0 nm and approximately 400.0 nm.The repeatabilities of the rootmean-square deviation measurements for the outer and inner profiles of the target were 2.6 and 2.4 nm,respectively.We believe our study provides a promising method for the high-resolution and nondestructive co-reference measurement of the inner and outer 3D profiles of laser fusion targets.展开更多
Mercury is a threatening pollutant in food,herein,we developed a Tb^(3+)-nucleic acid probe-based label-free assay for mix-and-read,rapid detection of mercury pollution.The assay utilized the feature of light-up fluor...Mercury is a threatening pollutant in food,herein,we developed a Tb^(3+)-nucleic acid probe-based label-free assay for mix-and-read,rapid detection of mercury pollution.The assay utilized the feature of light-up fluorescence of terbium ions(Tb^(3+))via binding with single-strand DNA.Mercury ion,Hg^(2+)induced thymine(T)-rich DNA strand to form a double-strand structure(T-Hg^(2+)-T),thus leading to fluorescence reduction.Based on the principle,Hg^(2+)can be quantified based on the fluorescence of Tb^(3+),the limit of detection was 0.0689μmol/L and the linear range was 0.1-6.0μmol/L.Due to the specificity of T-Hg^(2+)-T artificial base pair,the assay could distinguish Hg^(2+)from other metal ions.The recovery rate was ranged in 98.71%-101.34%for detecting mercury pollution in three food samples.The assay is low-cost,separation-free and mix-to-read,thus was a competitive tool for detection of mercury pollution to ensure food safety.展开更多
Coaxial plasma guns are a type of plasma source that produces plasma which propagates radially and axially controlled by the shape of the ground electrode, which has attracted much interest in several applications. In...Coaxial plasma guns are a type of plasma source that produces plasma which propagates radially and axially controlled by the shape of the ground electrode, which has attracted much interest in several applications. In this work, a 120° opening angle of CPG nozzle is used as a plasma gun configuration that operates at the energy of 150 J. The ionization of polyethylene insulator between the electrodes of the gun produces a cloud of hydrogen and carbon plasma.The triple Langmuir probe and Faraday cup are used to measure plasma density and plasma temperature. These methods are used to measure the on-axis and off-axis plasma divergence of the coaxial plasma gun. The peak values of ion densities measured at a distance of 25 mm on-axis from the plasma gun are(1.6±0.5)×10^(19)m^(-3)and(2.8±0.6)×10^(19)m^(-3)for hydrogen and carbon plasma respectively and the peak temperature is 3.02±0.5 eV. The mean propagation velocity of plasma is calculated using the transit times of plasma at different distances from the plasma gun and is found to be 4.54±0.25 cm/μs and 1.81±0.18 cm/μs for hydrogen and carbon plasma respectively. The Debye radius is obtained from the measured experimental data that satisfies the thin sheath approximation. The shot-to-shot stability of plasma parameters facilitates the use of plasma guns in laboratory experiments. These types of plasma sources can be used in many applications like plasma opening switches, plasma devices, and as plasma sources.展开更多
文摘A refined reciprocating probe system was installed on the midplane of HL-2A tokamak. The system is developed in collaboration with the Institute of Scientific Instrument, Chinese Academy of Science in Shenyang.The system has been used to measure edge density, temperature, potential and their fluctuation profiles with 8 cm scan from scrapeoff layer to plasma boundary. The velocity of the reciprocating stroke is designed by 1 m ·s^-1.
基金supported by the National Magnetic Confinement Fusion Science Program of China(No.2017YFE0301700)National Natural Science Foundation of China(No.11635008).
文摘A fast radial scanning probe system was constructed for the Keda Torus eXperiment(KTX)to measure the profiles of boundary plasma parameters such as floating potential,electron density,temperature,transport fluxes,etc.The scanning probe system is driven by slow and fast motion mechanisms,corresponding to the stand-by movement of a stepping motor and the fast scanning movement of a high-torque servo-motor,respectively.In fast scanning,the scanner drives the probe radially up to 20 cm at a maximum velocity of 4.0 m s-1.A noncontact magnetic grating ruler with a high spatial resolution of 5μm is used for the displacement measurement.New scanning probe can reach the center of plasmas rapidly.The comparison of plasma floating potential profiles obtained by a fixed radial rake probe and the single scanning probe suggests that the high-speed scanning probe system is reliable for measuring edge plasma parameter profiles on the KTX device.
基金China Fusion Engineering Experimental Reactor General Integration and Engineering Design (No. 2017YFE0300503)National Natural Science Foundation of China (No. 11775258)the Comprehensive Research Facility for Fusion Technology Program of China (No. 2018-000052-73-01-001228)。
文摘A multi-voltage probe array system is designed to measure the coupling resistance of an ion cyclotron resonance frequency antenna. In the process of the antenna coupling resistance data extraction, the minimization algorithm, the original Levenberg–Marquardt algorithm, is replaced by the Broyden–Fletcher–Goldfarb–Shanno algorithm to achieve more stable and accurate results. Moreover, a simple model of the multi-voltage probe array was applied to simulate the performance of the Kalman filter, and to optimize the distance and position of the probes and probe number to mitigate the influence of the system noise on the rebuilt results. During the EAST experiment in 2019, a four-voltage probe array was applied to measure the coupling resistance of line 6 during high confined mode discharge. The measurement results by the multivoltage probe array system and the voltage/current probe pair show a good agreement.
文摘In order to obtain creditable data an applicable method to optimize parameters of the Langmuir probes and circuits in a stationary laboratory device is investigated and an experimental criterion of the probe dimension is developed. To obtain the electron temperature and density the Electron Energy Distribution Function (EEDF) approach with less computing time and more accurate results is applied, instead of the conventional slope approach. Moreover the influence of the vessel wall materials on the plasma density is discussed briefly, indicating that the dielectric wall is helpful to enhancing the electron density.
基金partially supported by National Natural Science Foundation of China(Nos.11875017,11875020,12175186 and 11905052)the National Magnetic Confinement Fusion Science Program of China(Nos.2019YFE03030002,2017YFE0301203 and 2018YFE0310100)the Sichuan Outstanding Youth Science Foundation(No.2020JDJQ0019)。
文摘A newly designed divertor Langmuir probe diagnostic system has been installed in a rare closed divertor of the HL-2A tokamak and steadily operated for the study of divertor physics involved edge-localized mode mitigation,detachment and redistribution of heat flux,etc.Two sets of probe arrays including 274 probe tips were placed at two ports(approximately 180°separated toroidally),and the spatial and temporal resolutions of this measurement system could reach6 mm and 1μs,respectively.A novel design of the ceramic isolation ring can ensure reliable electrical insulation property between the graphite tip and the copper substrate plate where plasma impurities and the dust are deposited into the gaps for a long experimental time.Meanwhile,the condition monitoring and mode conversion between single and triple probe of the probe system could be conveniently implemented via a remote-control station.The preliminary experimental result shows that the divertor Langmuir probe system is capable of measuring the high spatiotemporal parameters involved the plasma density,electron temperature,particle flux as well as heat flux during the ELMy H-mode discharges.
基金the National Natural Science Foundation of China(No.62173049)the Open Fund of the Hubei Key Laboratory of Oil and Gas Drilling and Production Engineering(Yangtze University),YQZC202309.
文摘Conventional conductivity methods for measuring the void fraction in gas-liquid multiphase systems are typically affected by accuracy problems due to the presence of fluid flow and salinity.This study presents a novel approach for determining the void fraction based on a reciprocating dynamic conductivity probe used to measure the liquid film thickness under forced annular-flow conditions.The measurement system comprises a cyclone,a conductivity probe,a probe reciprocating device,and a data acquisition and processing system.This method ensures that the flow pattern is adjusted to a forced annular flow,thereby minimizing the influence of complex and variable gas-liquid flow patterns on the measurement results;Moreover,it determines the liquid film thickness solely according to circuit connectivity rather than specific conductivity values,thereby mitigating the impact of salinity.The reliability of the measurement system is demonstrated through laboratory experiments.The experimental results indicate that,in a range of gas phase superficial velocities 5–20 m/s and liquid phase superficial velocities 0.079–0.48 m/s,the maximum measurement deviation for the void fraction is 4.23%.
基金supported by the National Key R&D Program of China(Grant No.2021YFC3001100).
文摘Liquid-liquid mixing,including homogeneous and heterogeneous mixing,widely exists in the chemical industry.How to quantitatively characterize the mixing performance is important for reactor assessment and development.As a convenient and direct method for mixing characterization,the chemical probe method uses some special test reactions to characterize the mixing results.Here,the working principle and selection requirements of this method are introduced,and some common chemical probe systems for homogeneous and heterogeneous mixing processes are reviewed.The characteristics and applications of these systems are illustrated.Finally,the development of the new system is proposed.
基金The authors would like to thank the Deanship of Scientific Research and the research ServicesSupport Unit(RSSU)at King Saud University for their support in this paper.
文摘The novel SoftwareDefined Networking(SDN)architecture potentially resolves specific challenges arising from rapid internet growth of and the static nature of conventional networks to manage organizational business requirements with distinctive features.Nevertheless,such benefits lead to a more adverse environment entailing network breakdown,systems paralysis,and online banking fraudulence and robbery.As one of the most common and dangerous threats in SDN,probe attack occurs when the attacker scans SDN devices to collect the necessary knowledge on system susceptibilities,which is thenmanipulated to undermine the entire system.Precision,high performance,and real-time systems prove pivotal in successful goal attainment through feature selection to minimize computation time,optimize prediction performance,and provide a holistic understanding of machine learning data.As the extension of astute machine learning algorithms into an Intrusion Detection System(IDS)through SDN has garnered much scholarly attention within the past decade,this study recommended an effective IDS under the Grey-wolf optimizer(GWO)and Light Gradient Boosting Machine(Light-GBM)classifier for probe attack identification.The InSDN dataset was employed to train and test the proposed IDS,which is deemed to be a novel benchmarking dataset in SDN.The proposed IDS assessment demonstrated an optimized performance against that of peer IDSs in probe attack detection within SDN.The results revealed that the proposed IDS outperforms the state-of-the-art IDSs,as it achieved 99.8%accuracy,99.7%recall,99.99%precision,and 99.8%F-measure.
基金Supported by Gansu Provincial Natural Science Foundation of China(Grant No.22JR5RA229)National Natural Science Foundation of China(Grant Nos.51807086,12162021)Hongliu Youth Found of Lanzhou University of Technology and Gansu Provincial Outstanding Graduate Student Innovation Star of China(Grant No.2021CXZX-453).
文摘A flexible or planar eddy current probe with a differential structure can suppress the lift-off noise during the inspection of defects.However,the extent of the lift-off effect on differential probes,including different coil structures,varies.In this study,two planar eddy current probes with differential pickup structures and the same size,Koch and circular probes,were used to compare lift-off effects.The eddy current distributions of the probes perturbed by 0°and 90°cracks were obtained by finite element analysis.The analysis results show that the 90°crack can impede the eddy current induced by the Koch probe even further at relatively low lift-off distance.The peak-to-peak values of the signal output from the two probes were compared at different lift-off distances using finite element analysis and experimental methods.In addition,the effects of different frequencies on the lift-off were studied experimentally.The results show that the signal peak-to-peak value of the Koch probe for the inspection of cracks in 90°orientation is larger than that of the circular probe when the lift-off distance is smaller than 1.2 mm.In addition,the influence of the lift-off distance on the peak-to-peak signal value of the two probes was studied via normalization.This indicates that the influence becomes more evident with an increase in excitation frequency.This research discloses the lift-off effect of differential planar eddy current probes with different coil shapes and proves the detection merit of the Koch probe for 90°cracks at low lift-off distances.
基金supported by the National Natural Science Foundation of China(82072432)the China-Japan Friendship Hospital Horizontal Project/Spontaneous Research Funding(2022-HX-JC-7)+1 种基金the National High Level Hospital Clinical Research Funding(2022-NHLHCRF-PY-20)the Elite Medical Professionals project of China-Japan Friendship Hospital(ZRJY2021-GG12).
文摘Rheumatoid arthritis(RA)is a systemic autoimmune disease that is primarily manifested as synovitis and polyarticular opacity and typically leads to serious joint damage and irreversible disability,thus adversely affecting locomotion ability and life quality.Consequently,good prognosis heavily relies on the early diagnosis and effective therapeutic monitoring of RA.Activatable fluorescent probes play vital roles in the detection and imaging of biomarkers for disease diagnosis and in vivo imaging.Herein,we review the fluorescent probes developed for the detection and imaging of RA biomarkers,namely reactive oxygen/nitrogen species(hypochlorous acid,peroxynitrite,hydroxyl radical,nitroxyl),pH,and cysteine,and address the related challenges and prospects to inspire the design of novel fluorescent probes and the improvement of their performance in RA studies.
基金supported by the natural science foundation reserve project of Jiangsu Agri-animal Husbandry Vocational College(No.NSF2023CB14).
文摘Feline calicivirus(FCV)was a highly prevalent RNA virus causing upper respiratory tract infections in cats through the mouth and nose around the world,result in the death of cats especially under 1 year old with upper respiratory tract disease(URTD)and virulent systemic disease(FCV-VSD)[1].Infected cats usually presented with mouth ulcers,salivation and gingivitis-stomatitis.Furthermore,both recovered cats and asymptomatic carriers can still carry and spread the FCV virus for extended periods of time,contributing to the potential for outbreak.This presented a significant threat to the health and lives of cats,and rare wildlife and took a heavy financial loss on the pet industry,making the prevention and control of the virus difficult.Hence,rapid identification of FCV in clinical samples was necessary to prevent the spread of FCV and avoid financial loss.
基金supported by the National Key Research and Development Program of China(Grant No.2021YFA1400400)the Fundamental Research Funds for the Central Universities,and the National Natural Science Foundation of China(Grant Nos.12174029 and 11922402).
文摘Uniaxial strain is a powerful tuning parameter that can control symmetry and anisotropic electronic properties in iron-based superconductors.However,accurately characterizing anisotropic strain can be challenging and complex.Here,we utilize a cryogenic optical system equipped with a high-spatial-resolution microscope to characterize surface strains in iron-based superconductors using the digital image correlation method.Compared with other methods such as high-resolution x-ray diffraction,strain gauge,and capacitive sensor,digital image correlation offers a non-contact full-field measurement approach,acting as an optical virtual strain gauge that provides high spatial resolution.The results measured on detwinned BaFe_(2)As_(2)are quantitatively consistent with the distortion measured by x-ray diffraction and neutron Larmor diffraction.These findings highlight the potential of cryogenic digital image correlation as an effective and accessible tool for probing the isotropic and anisotropic strains,facilitating applications of uniaxial strain tuning in research of quantum materials.
基金Project supported by the National Natural Science Foundation of China (Grant No.11905076)S&T Program of Hebei (Grant No.SZX2020034)。
文摘A novel emissive probe consisting of an oxide cathode coating is developed to achieve a low operating temperature and long service life.The properties of the novel emissive probe are investigated in detail,in comparison with a traditional tungsten emissive probe,including the operating temperature,the electron emission capability and the plasma potential measurement.Studies of the operating temperature and electron emission capability show that the tungsten emissive probe usually works at a temperature of 1800 K-2200 K while the oxide cathode emissive probe can function at about 1200 K-1400 K.In addition,plasma potential measurements using the oxide cathode emissive probe with different techniques have been accomplished in microwave electron cyclotron resonance plasmas with different discharge powers.It is found that a reliable plasma potential can be obtained using the improved inflection point method and the hot probe with zero emission limit method,while the floating point method is invalid for the oxide cathode emissive probe.
基金Project supported by the National Key Research and Development Program of China(Grant No.2021YFB2012600)the Science and Technology Plan Project of State Administration of Market Regulation,China(Grant No.2021MK039)。
文摘An integrated quantum probe for magnetic field imaging is proposed,where the nitrogen–vacancy(NV)center fixed at the fiber tip is located on the periphery of flexible ring resonator.Using flexible polyimide(PI)as the substrate medium,we design a circular microstrip antenna,which can achieve a bandwidth of 140 MHz at Zeeman splitting frequency of 2.87 GHz,specifically suitable for NV center experiments.Subsequently,this antenna is seamlessly fixed at a three-dimensional-printed cylindrical support,allowing the optical fiber tip to extend out of a dedicated aperture.To mitigate errors originating from processing,precise tuning within a narrow range can be achieved by adjusting the conformal amplitude.Finally,we image the microwave magnetic field around the integrated probe with high resolution,and determine the suitable area for placing the fiber tip(SAP).
基金support received from the National Natural Science Foundation of China(GrantNos.62204204 and 52175148)Science and Technology Innovation 2030-Major Project(Grant No.2022ZD0208601)+1 种基金Shanghai Sailing Program(Grant No.21YF1451000)Presidential Foundation of CAEP(Grant No.YZJJZQ2022001).
文摘Implanted neural probes can detect weak discharges of neurons in the brain by piercing soft brain tissue,thus as important tools for brain science research,as well as diagnosis and treatment of brain diseases.However,the rigid neural probes,such as Utah arrays,Michigan probes,and metal microfilament electrodes,are mechanically unmatched with brain tissue and are prone to rejection and glial scarring after implantation,which leads to a significant degradation in the signal quality with the implantation time.In recent years,flexible neural electrodes are rapidly developed with less damage to biological tissues,excellent biocompatibility,and mechanical compliance to alleviate scarring.Among them,the mechanical modeling is important for the optimization of the structure and the implantation process.In this review,the theoretical calculation of the flexible neural probes is firstly summarized with the processes of buckling,insertion,and relative interaction with soft brain tissue for flexible probes from outside to inside.Then,the corresponding mechanical simulation methods are organized considering multiple impact factors to realize minimally invasive implantation.Finally,the technical difficulties and future trends of mechanical modeling are discussed for the next-generation flexible neural probes,which is critical to realize low-invasiveness and long-term coexistence in vivo.
基金supported by National Natural Science Foundation of China(No.22278308,22109114 and 22102099)。
文摘Lithium hexafluorophosphate(LiPF_(6)),the most commonly used lithium battery electrolyte salt,is vulnerable to heat and humidity.Quantitative and qualitative determination the variation of LiPF_(6)have always relied on advanced equipment.Herein,we develop a fast,convenient,high-selective fluorescence detection method based on metal-organic cages(MOC),whose emission is enhanced by nearly 20 times in the presence of LiPF_(6)with good stability and photobleaching resistance.The fluorescent probe can also detect moisture in battery electrolyte.We propose and verify that the luminescence enhancement is due to the presence of hydrogen bond-induced enhanced emission effect in cages.Fluorescent excitation-emission matrix spectra and variable-temperature nuclear magnetic resonance spectroscopy are employed to clarify the role of hydrogen bonds in guest-loaded cages.Density functional theory(DFT)calculation is applied to simulate the structure of host-guest complexes and estimate the adsorption energy involved in the system.The precisely matched lock-and-key model paves a new way for designing and fabricating novel host structures,enabling specific recognition of other target compounds.
基金supported by the National Natural Science Foundation of China(52327806 and U22A6006).
文摘The high-resolution and nondestructive co-reference measurement of the inner and outer threedimensional(3D)surface profiles of laser fusion targets is difficult to achieve.In this study,we propose a laser differential confocal(LDC)–atomic force probe(AFP)method to measure the inner and outer 3D surface profiles of laser fusion targets at a high resolution.This method utilizes the LDC method to detect the deflection of the AFP and exploits the high spatial resolution of the AFP to enhance the spatial resolution of the outer profile measurement.Nondestructive and co-reference measurements of the inner profile of a target were achieved using the tomographic characteristics of the LDC method.Furthermore,by combining multiple repositionings of the target using a horizontal slewing shaft,the inner and outer 3D surface profiles of the target were obtained,along with a power spectrum assessment of the entire surface.The experimental results revealed that the respective axial and lateral resolutions of the outer profile measurement were 0.5 and 1.3 nm,while the respective axial and lateral resolutions of the inner profile measurement were 2.0 nm and approximately 400.0 nm.The repeatabilities of the rootmean-square deviation measurements for the outer and inner profiles of the target were 2.6 and 2.4 nm,respectively.We believe our study provides a promising method for the high-resolution and nondestructive co-reference measurement of the inner and outer 3D profiles of laser fusion targets.
基金financially supported by National Natural Science Foundation of China(22074100)the Young Elite Scientist Sponsorship Program by CAST(YESS20200036)+3 种基金the Researchers Supporting Project Number RSP-2021/138King Saud University,Riyadh,Saudi ArabiaTechnological Innovation R&D Project of Chengdu City(2019-YF05-31702266-SN)Sichuan University-Panzhihua City joint Project(2020CDPZH-5)。
文摘Mercury is a threatening pollutant in food,herein,we developed a Tb^(3+)-nucleic acid probe-based label-free assay for mix-and-read,rapid detection of mercury pollution.The assay utilized the feature of light-up fluorescence of terbium ions(Tb^(3+))via binding with single-strand DNA.Mercury ion,Hg^(2+)induced thymine(T)-rich DNA strand to form a double-strand structure(T-Hg^(2+)-T),thus leading to fluorescence reduction.Based on the principle,Hg^(2+)can be quantified based on the fluorescence of Tb^(3+),the limit of detection was 0.0689μmol/L and the linear range was 0.1-6.0μmol/L.Due to the specificity of T-Hg^(2+)-T artificial base pair,the assay could distinguish Hg^(2+)from other metal ions.The recovery rate was ranged in 98.71%-101.34%for detecting mercury pollution in three food samples.The assay is low-cost,separation-free and mix-to-read,thus was a competitive tool for detection of mercury pollution to ensure food safety.
基金supported by Bhabha Atomic Research Centre, Department of Atomic Energy, Government of IndiaDepartment of Atomic Energy, Government of India for financial assistance under DAE Doctoral Fellowship Scheme-2018。
文摘Coaxial plasma guns are a type of plasma source that produces plasma which propagates radially and axially controlled by the shape of the ground electrode, which has attracted much interest in several applications. In this work, a 120° opening angle of CPG nozzle is used as a plasma gun configuration that operates at the energy of 150 J. The ionization of polyethylene insulator between the electrodes of the gun produces a cloud of hydrogen and carbon plasma.The triple Langmuir probe and Faraday cup are used to measure plasma density and plasma temperature. These methods are used to measure the on-axis and off-axis plasma divergence of the coaxial plasma gun. The peak values of ion densities measured at a distance of 25 mm on-axis from the plasma gun are(1.6±0.5)×10^(19)m^(-3)and(2.8±0.6)×10^(19)m^(-3)for hydrogen and carbon plasma respectively and the peak temperature is 3.02±0.5 eV. The mean propagation velocity of plasma is calculated using the transit times of plasma at different distances from the plasma gun and is found to be 4.54±0.25 cm/μs and 1.81±0.18 cm/μs for hydrogen and carbon plasma respectively. The Debye radius is obtained from the measured experimental data that satisfies the thin sheath approximation. The shot-to-shot stability of plasma parameters facilitates the use of plasma guns in laboratory experiments. These types of plasma sources can be used in many applications like plasma opening switches, plasma devices, and as plasma sources.