The intestinal microbiota has a vital role in human health.Especially,Bifidobacteriumis a genus that is crucial for health and different diseases.Further potentially functional investigation of Bifidobacteriumis neede...The intestinal microbiota has a vital role in human health.Especially,Bifidobacteriumis a genus that is crucial for health and different diseases.Further potentially functional investigation of Bifidobacteriumis needed,which will be of great importance to human health.This review aims to describe bifidobacteria compositional changes associated with different ages,to highlight the impact of bifidobacteria on health and disease,and to indicate their clinical applications.Bifidobacterium longum,B.breve,and B.bifidumare dominant in infants,whereas B.catenulatumand B.adolescentis are more prevalent in adults.Bifidobacteria improve the treatment of diarrhea,inflammatory bowel disease(IBD),colon irregularity,colorectal cancer,necrotizing enterocolitis,diabetes and disorder of carbohydrate metabolism.展开更多
文摘The intestinal microbiota has a vital role in human health.Especially,Bifidobacteriumis a genus that is crucial for health and different diseases.Further potentially functional investigation of Bifidobacteriumis needed,which will be of great importance to human health.This review aims to describe bifidobacteria compositional changes associated with different ages,to highlight the impact of bifidobacteria on health and disease,and to indicate their clinical applications.Bifidobacterium longum,B.breve,and B.bifidumare dominant in infants,whereas B.catenulatumand B.adolescentis are more prevalent in adults.Bifidobacteria improve the treatment of diarrhea,inflammatory bowel disease(IBD),colon irregularity,colorectal cancer,necrotizing enterocolitis,diabetes and disorder of carbohydrate metabolism.