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Liquid-liquid Extraction System Based on Non-ionic Surfactant-salt-H_2O and Mechanism of Drug Extraction 被引量:3
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作者 LeiLI FengLIU 《Chinese Chemical Letters》 SCIE CAS CSCD 2002年第4期349-350,共2页
Extraction behavior of chlorpromazine hydrochloride (CPZ) and procaine hydro- chloride (PCN) in the system described in the title was studied. Research shows that the extraction efficiency of CPZ can amount to 96% by... Extraction behavior of chlorpromazine hydrochloride (CPZ) and procaine hydro- chloride (PCN) in the system described in the title was studied. Research shows that the extraction efficiency of CPZ can amount to 96% by twice extraction, while that of PCN is 77%. This system produces the distribution coefficients (KD) of 12.3 and 2.6 respectively for CPZ and PCN. Extraction mechanism is deduced according to ultraviolet and molecular fluorescence spectra variation of the drugs in the system studied. 展开更多
关键词 Non-ionic surfactant-salt-H2O extraction system polyethylene glycol-1000 chlor- promazine hydrochloride procaine hydrochloride mechanism of extraction.
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