Pancreatic Carcinoma with Prominent Mucin Production: A Clinicopathologic and Immunohistochemical Study of 9 Cases

Pancreatic carcinoma occasionally associated with prominent mucin production and this type of tumor designated as PCM (pancreatic carcinoma with prominent mucin production) was diagnosed depends on subjective estimation of the amount of mucous area, and there has been no report on a quantitative evaluation of the amount of mucinous area in the tumor. To examine the feature of PCM, we analyzed 9 cases of PCM among 243 cases of pancreas carcinoma and evaluated the amount of mucin by imaging analysis. Morphologically, 5 cases were classified as intradactal papillary mucinous neoplasms (IPMN)-derived PCM and 4 cases were as ductal adenocarcinoma (DA)-derived PCM. Mucous composition was found to be more than 50% in all IPMN-derived PCM cases, and that was 40% - 50% in DA-derived PCM cases with one exception. IPMN-derived PCM cases showed expansive growth with pancreatic duct dilatation filled with mucin, while DA-derived PCM cases possessed mucin infiltration into interstitial tissue. Immunohisto-chemically, three of 4 DA-derived PCM cases were MUC1(–)/MUC2(+), and the results of expressions for p16 and Dpc4 suggesting that DA-derived PCM was similar to IPMN-derived PCM rather than ordinary DA. Survival rate of DA-derived PCM cases was lower than that of IPMN-derived PCM cases. We advocate that DA-derived PCM may constitute a borderline group between IPMN and ordinary DA.

WANG Cheng-bai(汪承柏)--A Prominent Hepatologist of integrative Medicine

Prof. WANG Cheng-bai, male, was born in Hunan Province, October 1926. He started working as a physician in 1947, and was assigned to Dalian Medical College for further

YAN Yong-qing(严永清)——A Prominent Integrative Pharmacist

YAN Yongqing,male,bornin July 1934 inShanghai,wasgraduated fromthe PharmaceuticsDepartment ofNortheast Pharmaceutical College(Shenyang Phar-maceutical Univer-

SUN Yan (孙燕)——A Prominent Oncologist of Internal Medicine

Professor SUN Yan, a famous medical oncologist, was graduated from Yenching University with a B. S. degree in 1951, and from Peking Union Medical College with a M.D. degree in 1956. He studied traditional Chinese medicine from 1960 to 1961, and worked, between 1979 and 1980, as a visiting professor in M. D. Anderson Cancer Center, USA. Since 1959, he has been working in the Department of Medical Oncology in Cancer Hospital of Chinese Academy of Medical Sciences （CAMS）, holding the post of professor ＆ director of Department of Medical Oncology during 1986-1994. He was honored as the ＂Outstanding Physician＂ by CAMS and Peking Union Medical College （PUMC） in 1993, designated as an ＂Advanced Worker＂ in national health care system by the Ministry of Human Affairs in 1994, and elected an academician of Chinese Academy of Engineering in 1999. Since 1991, he has been enjoying the governmental special stipend.

Chong-Chet Anterior Scoring Technique for the Correction of Prominent Ears: Results in 30 Patients

A lot ofotoplasty techniques have been developed during the past years. However, there is no single perfect technique which is worldwide accepted. We present our assessment of a Chong-Chet anterior scoring technique for the correction of prominent ears which we applied in 30 patients between 2005 and 2010. This study is a report of creating a natural fold of cartilage using Chong-Chet anterior scoring technique by cartilage incision at the border between the antihelix and scapha, with medial scoring of the scapha and lateral scoring of the antihelix. Sutures were used to maintain the created fold. There were no major complications at the 1-year follow-up evaluation. None of the patients developed a recurrence, or retro protrusion of the helix which required a second operation for correction. The procedure is a simple surgical technique. The reconstructed ear shows reliable results in stability, size and normal convolutions. Furthermore, sharp cartilaginous ridges and hidden helix are avoided.

Carving out a Niche African football players feature prominently in the Chinese leagues

The Chinese Football Association Super League （CSL） has broken yet another record. Indeed, the league＇s record recruitment budget of 388 million euros （$342.76 million） yeas broken this season. In 2018, more than 470 million euros （$415.19 million） have been spent on retaining the best football stars that have come to China in recent years, as well as on attracting even more talented footballers.

Is it a normal phenomenon for pediatric patients to have brain leptomeningeal contrast enhancement on 3-tesla magnetic resonance imaging?

Determining whether sevoflurane sedation in children leads to“pseudo”prominent leptomeningeal contrast enhancement(pLMCE)on 3 Tesla magnetic resonance imaging will help reduce overdiagnosis by radiologists and clarify the pathophysiological changes of pLMCE.

A Confined Two-peaked Solar Flare Observed by EAST and SDO

The solar flare is one of the most violent explosions,and can disturb the near-Earth space weather.Except for commonly single-peaked solar flares in soft X-ray,some special flares show intriguing a two-peak feature that is deserved much more attentions.Here,we reported a confined two-peaked solar flare and analyzed the associated eruptions using high-quality observations from Educational Adaptive-optics Solar Telescope and Solar Dynamics Observatory.Before the flare,a magnetic flux rope(MFR)formed through partially tether-cutting reconnection between two sheared arches.The flare occurred after the MFR eruption that was confined by the overlying strong field.Interestingly,a small underlying filament immediately erupted,which was possibly destabilized by the flare ribbon.The successive eruptions were confirmed by the analysis of the emission measure and the reconnection fluxes.Therefore,we suggest that the two peaks of the confined solar flare are corresponding to two episodes of magnetic reconnection during the successive eruptions of the MFR and the underlying filament.

Prominent myalgia-an important clue in the diagnosis of a muscle disorder

Adevelopmentally normal,15-year-old boy presented with complaint of gait abnormalities since 8 years of age.The child complained of difficulty in climbing stairs and running.He could not climb stairs without the support of railing.There was no problem with rising from sitting or lying down position.

Appearance of prominent milia as secondary lesions during recovery of refractory bullous pemphigoid:a case report

Introduction Bullous pemphigoid (BP) is an autoimmune blistering disease that affects patients of advanced age. BP is characterized clinically by tense bullae on the extremities and trunk, histopathologically by subepi-dermal blisters with eosinophilic infiltration, and immunologically by autoantibodies to BP180 and BP230. Direct immunofluorescence of perilesional skin shows depositions of IgG and C3 in the basement membrane zone(1)BP rarely shows prominent milia formation, which is a hallmark of epidermolysis bullosa acquisita. We herein describe a 53-year-old man with refractory BP showing numerous milia during recovery.

LyαEmission Enhancement Associated with Soft X-Ray Microflares

Lyα(Lyα,1216 A)is the strongest emission line in the solar ultraviolet spectrum.In the present work,we obtained a Lyαenhancement catalog covering flares larger than B1 class from the GOES/EUVS data during 2010-2016.We focused on the 242 B-class events which are less investigated,however,show non-negligible Lyαemission enhancement.We found that on average the Lyαpeak of B-class flares is 0.85%stronger than the background.For the flare energetics,it is found that the weaker the soft X-ray(SXR)flare,the larger the ratio of the radiated energy in Lyαto SXR.Using the RHESSI data and multi-wavelength observations taken by SDO-AIA,we diagnose the thermal and non-thermal properties of several flares.Three case studies show that the coincidence of the Lyαpeak with the SXR time-derivative peak is not a sufficient condition of the nonthermal property of a Lyαmicroflare.The Lyαenhancement in the microflares may be caused by the nonthermal electron beams or/and thermal conduction.However for typeⅢevents,we found that the delay of the Lyαpeak with respect to the SXR peak can be attributed to either the Lyαemission from a filament erupted or the cooling of the thermal plasma in flare loops.Furthermore,interestingly the Lyαemission from filaments can not only occur in the decay phase of the flare,but also in the preflare phase.In this case,the Lyαemission was originated from an erupted filament which probably initiated the flare.

A Cognitive Study of the Naming Elements of Chinese Dish Names Based on the Prominence Principle

The assortedness of Chinese food,together with the complexity of their naming elements,has ignited numerous scholars' interests in this field and prompted them to make abundant analyses of Chinese dish names.Most of them,however,were done in studies of traditional linguistics,rhetoric,translatology and cross-cultural communication.And studies,based on corpus,on the naming elements of Chinese dishes under cognitive linguistic theories almost remain a blank.This paper aims to conduct a quantitative analysis of 4,000 Chinese dish names(500 ones selected freely from each of the eight cuisines),based on the Prominence Principle,in order to identify the specific naming elements of Chinese dishes and forward related statistics and ratios.

Live And Love——Brave Theme Features In Canadian Classical Novels

Canadian classical works are becoming more and more popular all over the world. People began to understand and mar-vel at the Canadian literatures that are quite life-meaningful and full of lessons and tips for lives. The classic works in CanadianLiteratures that advantageously elaborated the characteristics of sublimation under the background for Canada's particular history,geography, climate, religion, demographic factors, generation, development and continuous construction of Canadian literatures.The greatest masterpieces can highlight powerfully the certain mindset of Canadian and the permanent theme for Canadian Litera-ture: keep working hard for survival and love bravely. Meanwhile, modern people will learn a lot from reading Canadian classic lit-erary works.

最小空间中的智能——带有联络通讯功能的分析-测量变换器

由ProMinent公司在市场上推出的新型的DMTa分析-测量变换器可以在流程工业的各个领域可靠地测量pH值、温度、氧化还原值、氯浓度和电导率。

Fine-scale structures and material flows of quiescent filaments observed by the New Vacuum Solar Telescope

Study of the small-scale structures and material flows associated with solar quiescent filaments is very important for understanding the formation and equilibrium of solar filaments. Using high resolution Ha data observed by the New Vacuum Solar Telescope, we present the structures of barbs and material flows along the threads across the spine in two quiescent filaments on 2013 September 29 and on 2012 November 2, respectively. During the evolution of the filament barb, several paral- lel tube-shaped structures formed and the width of the structures ranged from about 2.3 Mm to 3.3 Mm. The parallel tube-shaped structures merged together accompanied by material flows from the spine to the barb. Moreover, the boundary between the barb and surrounding atmosphere was very neat. The counter-streaming flows were not found to appear alternately in the adjacent threads of the filament. However, the large-scale patchy counter-streaming flows were detected in the filament. The flows in one patch of the filament have the same direction but flows in the adjacent patch have opposite direction. The patches of two opposite flows with a size of about 10＂ were alternately exhibited along the spine of the filament. The velocity of these material flows ranged from 5.6 km s^-1 to 15.0 km s^-1. The material flows along the threads of the filament did not change their direction for about two hours and fourteen minutes during the evolution of the filament. Our results confirm that the large-scale counter- streaming flows with a certain width along the threads of solar filaments exist and are coaligned well with the threads.

Dependence of the length of solar filament threads on the magnetic configuration

High-resolution Ha observations indicate that filaments consist of an as- sembly of thin threads. In quiescent filaments, the threads are generally short, whereas in active region filaments, the threads are generally long. In order to explain these observational features, we performed one-dimensional radiative hydrodynamic sim- ulations of filament formation along a dipped magnetic flux tube in the framework of the chromospheric evaporation-coronal condensation model. The geometry of a dipped magnetic flux tube is characterized by three parameters, i.e., the depth （D）, the half-width （w） and the altitude （h） of the magnetic dip. A survey of the parame- ters in numerical simulations shows that when allowing the filament thread to grow in 5 days, the maximum length （Lth） of the filament thread increases linearly with w, and decreases linearly with D and h. The dependence is fitted into a linear function Lth = 0.84w --0.88D - 2.78h ＋ 17.31 （Mm）. Such a relation can qualitatively explain why quiescent filaments have shorter threads and active region filaments have longer threads.

Magnetic flux ropes in the solar corona: structure and evolution toward eruption

Magnetic flux ropes are characterized by coherently twisted magnetic field lines,which are ubiquitous in magnetized plasmas.As the core structure of various eruptive phenomena in the solar atmosphere,flux ropes hold the key to understanding the physical mechanisms of solar eruptions,which impact the heliosphere and planetary atmospheres.The strongest disturbances in the Earth’s space environments are often associated with large-scale flux ropes from the Sun colliding with the Earth’s magnetosphere,leading to adverse,sometimes catastrophic,space-weather effects.However,it remains elusive as to how a flux rope forms and evolves toward eruption,and how it is structured and embedded in the ambient field.The present paper addresses these important questions by reviewing current understandings of coronal flux ropes from an observer’s perspective,with an emphasis on their structures and nascent evolution toward solar eruptions,as achieved by combining observations of both remote sensing and in-situ detection with modeling and simulation.This paper highlights an initiation mechanism for coronal mass ejections(CMEs)in which plasmoids in current sheets coalesce into a’seed’flux rope whose subsequent evolution into a CME is consistent with the standard model,thereby bridging the gap between microscale and macroscale dynamics.

Can an injection model replenish filaments in a weak magnetic environment?

We observed an Hα surge that occurred in NOAA Active Region 12401 on 2015 August 17, and we discuss its trigger mechanism, and kinematic and thermal properties. It is suggested that this surge was caused by a chromospheric reconnection which ejected cool and dense material with transverse velocity of about 21–28 km s-1 and initial Doppler velocity of 12 km s^-1. This surge is similar to the injection of newly formed filament materials from their footpoints, except that the surge here occurred in a relatively weak magnetic environment of 100 G. Thus, we discuss the possibility of filament material replenishment via the erupting mass in such a weak magnetic field, which is often associated with quiescent filaments. It is found that the local plasma can be heated up to about 1.3 times the original temperature, which results in an acceleration of about –0.017 km s^-2. It can lift the dense material up to 10 Mm and higher with an inclination angle smaller than 50°, namely the typical height of active region filaments, but it can hardly inject the material up to those filaments higher than 25 Mm, like some quiescent filaments. Thus, we think that the injection model does not work well in describing the formation of quiescent filaments.

Some interesting topics provoked by the solar filament research in the past decade

Solar filaments are an intriguing phenomenon,like cool clouds suspended in the hot corona.Similar structures exist in the intergalactic medium as well.Despite being a long-studied topic,solar filaments have continually attracted intensive attention because of their link to coronal heating,coronal seismology,solar flares and coronal mass ejections(CMEs).In this review paper,by combing through the solar filament-related work done in the past decade,we discuss several controversial topics,such as the fine structures,dynamics,magnetic configurations and helicity of filaments.With high-resolution and highsensitivity observations,combined with numerical simulations,it is expected that resolving these disputes will definitely lead to a huge leap in understanding the physics related to solar filaments,and even shed light on galactic filaments.