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Epidemiological and Diagnostic Aspects of Childhood Proptosis in Lome (Togo) from 2010 to 2020
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作者 Nidain Maneh Mawuli Ayodele Komi Santos +5 位作者 Koffi Sylvain Kawilitetou Dadjo Amouzou Kossi Dzidzinyo Kokou Vonor Didier Koffi Ayena Patrice Komi Balo 《Open Journal of Ophthalmology》 2023年第4期333-340,共8页
Background: Although proptosis is rare, it is nevertheless the main sign of orbital disease. Its discovery usually indicates a serious eye disease especially in children. Objective: To determine epidemiological and di... Background: Although proptosis is rare, it is nevertheless the main sign of orbital disease. Its discovery usually indicates a serious eye disease especially in children. Objective: To determine epidemiological and diagnostic aspects of childhood proptosis in Lome (Togo). Methods: Retrospective cross-sectional study conducted from June 2010 to May 2020, which is 10 years, in the ophthalmology department of CHU-campus of Lome. Files of patients between the age of 0 and 15 who presented a proptosis during the study period were taken into account in the study. Patients with a false proptosis or incomplete records during the study period were not taken into account in the study. Results: The study considered 42 children with an age average of 7.63 years ± 4.96 [4 days;15 years] and a sex-ratio of 1.33. The frequency of proptosis was 0.5% with an average progression of 383.7 days before the first consultation. The proptosis was unilateral in 80.95% of cases. The orbito-cerebral CT scan was done in 47.62% of cases. The proptosis in these patients was predominantly of grade 3 in 45% of cases. The tumor pathologies were at the forefront in 35.71%, dominated by retinoblastoma, and followed by infectious and inflammatory diseases in 14.29%. Conclusion: Childhood proptosis is rare and often indicative of infectious and tumor pathologies in our context. Its diagnosis is delayed, which shows the importance of an early and effective diagnosis. . 展开更多
关键词 Childhood proptosis TUMORS INFECTIONS Lome
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Disseminated cysticercosis presenting with bilateral proptosis: A case report
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作者 Ravindra Kumar Garg Neeraj Kumar +1 位作者 Imran Rizvi Hardeep Singh Malhotra 《Asian Pacific Journal of Tropical Medicine》 SCIE CAS 2019年第7期337-338,共2页
Rationale: Disseminated cysticercosis is characterized by presence of cysts in multiple body organs, like brain, skin, eyes, muscles and rarely heart and lungs.Patient concerns: A 22-year-old man presented with bilate... Rationale: Disseminated cysticercosis is characterized by presence of cysts in multiple body organs, like brain, skin, eyes, muscles and rarely heart and lungs.Patient concerns: A 22-year-old man presented with bilateral proptosis of 1-year duration. He also had two episodes of cysticercosis encephalitis. In the second episode of encephalopathy, the patient died.Diagnosis: Disseminated cysticercosis.Interventions: Corticosteroids(Initially intravenous dexamethasone 0.4 mg/kg/day for 2 weeks, followed by oral prednisolone 1.0 mg/kg/day).Outcomes: The patient died of cysticercosis encephalitis approximately 2 months later.Lessons: Disseminated cysticercosis in our case presented only with proptosis as he had very heavy infestation of the brain and eyes. Heavy larval infestation in a patient with disseminated cysticercosis can be life-threatening. 展开更多
关键词 NEUROCYSTICERCOSIS CYSTICERCOSIS ENCEPHALITIS proptosis
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Proptosis in orbital myeloid sarcoma: A precursor to acute leukaemia
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作者 Fhun LC Tai ELM +2 位作者 Wan-Hazabbah WH Liza-Sharmini AT Chong MF 《Journal of Acute Disease》 2017年第3期134-136,共3页
Myeloid sarcoma is a rare, aggressive presentation of acute myeloid leukemia which tends to affect bones and soft tissue. It is usually seen in children, and has a poor prognosis. We report a case of orbital myeloid s... Myeloid sarcoma is a rare, aggressive presentation of acute myeloid leukemia which tends to affect bones and soft tissue. It is usually seen in children, and has a poor prognosis. We report a case of orbital myeloid sarcoma presenting with unilateral proptosis in a young adult who subsequently developed acute myeloid leukaemia. An 18-year-old male presented with sudden, progressively increasing right eye swelling over two weeks. Examination revealed right eye proptosis, with a positive relative afferent papillary defect and a right eye visual acuity of 6/60, pinhole 6/18. The right fundus showed optic disc hyperemia, tortuous veins and choroidal folds. The left eye was normal. On initial examination, computed tomography (CT) of the brain and orbit showed an enhancing mass at the lateral aspect of the right orbit measuring 3.8 x 2.1 cm, with optic nerve displacement. Right lateral orbitotomy and excisional biopsy yielded a tissue diagnosis of myeloid sarcoma. The peripheral blood smear was normal at this time. The patient defaulted treatment but presented again three months later with right eye massive proptosis and loss of vision. A repeated CT scan showed a large lobulated mass measuring 104.5mm x 87.21mmm x 77.25mm occupying the right orbit, with destruction of the bony orbital walls and intracranial extension. A repeat full blood picture and bone marrow aspiration showed 30% blast cells, consistent with the diagnosis of acute myeloid leukemia. Patient was started on chemotherapy and radiotherapy. The tumour regressed after five cycles, but unfortunately, patient passed away due to brain metastases. 展开更多
关键词 proptosis LEUKEMIA ORBITAL MYELOID SARCOMA
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A Rapidly Progressive Proptosis, a Case Report
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作者 Afshin Tajdini Mazen Sinjab Somer Hassan 《Open Journal of Ophthalmology》 2012年第2期37-39,共3页
In contrast to intraocular metastases, orbital metastases are a rare manifestation of systemic malignancies;such orbital metastases account for only 1% - 13% of all orbital tumors. Such tumors grow rapidly;they may un... In contrast to intraocular metastases, orbital metastases are a rare manifestation of systemic malignancies;such orbital metastases account for only 1% - 13% of all orbital tumors. Such tumors grow rapidly;they may undergo necrosis, as the rate of tumor angiogenesis cannot keep pace with the rapidly expanding mass. Here, we report a rare case of an orbital metastasis from a nasopharyngeal carcinoma. 展开更多
关键词 proptosis ORBITAL Metastasis NASOPHARYNGEAL CARCINOMA UNDIFFERENTIATED CARCINOMA
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Unusual Case of Unilateral Neonatal Eyeball Luxation: A Case Report
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作者 Abdullah S. Alghamdi Muhammed S. Alrajeh +4 位作者 Ahmad S. Alsalem Silvana Schellini Azzah Maktabi Amal Alhumaidan Diego Strianese 《Open Journal of Ophthalmology》 2024年第1期69-75,共7页
The newborn infant presented with severe proptosis. Data on clinical history, presentation, photos, radiological imaging, and laboratory results were presented. A literature review was conducted for the case and relev... The newborn infant presented with severe proptosis. Data on clinical history, presentation, photos, radiological imaging, and laboratory results were presented. A literature review was conducted for the case and relevant treatment modalities. The surgical technique and the outcome were also discussed. The mass was present since birth in a full term neonate, causing complete globe dislocation of the left eye. Imaging showed a large cystic retro-bulbar mass completely occupying the orbital cavity and causing anterior dislocation of the left globe. Surgical excision of the tumor was carried out with globe preservation and Histopathology examination confirmed the diagnosis of optic nerve glioma. This was an atypical presentation of an optic nerve glioma causing globe dislocation in a neonate. The resection of such a large orbital tumor made globe preservation possible and resulted in an excellent cosmetic outcome. . 展开更多
关键词 Neonatal proptosis Optic Nerve Glioma Globe Dislocation Globe Preservation Cosmetic Surgery
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Orbital liposarcoma: a retrospective, single-center study of thirteen patients 被引量:1
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作者 Ning Gao Xin Ge +2 位作者 Cheng Pei Jian-Min Ma Ya-Guang Hu 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2023年第8期1293-1298,共6页
AIM:To explore the clinical and pathological characteristics of thirteen patients with orbital liposarcoma.METHODS:The clinical history data of thirteen patients diagnosed as orbital liposarcoma at Beijing Tongren Hos... AIM:To explore the clinical and pathological characteristics of thirteen patients with orbital liposarcoma.METHODS:The clinical history data of thirteen patients diagnosed as orbital liposarcoma at Beijing Tongren Hospital,from 2006 to 2021 were collected and analyzed.The data includes age,gender,affected orbital side,course of disease,status of disease(primary or recurrent),clinical manifestations,preoperative visual acuity,operative treatment,the relations between liposarcoma and surrounding tissue,longest diameter of liposarcoma,histological subtype,immunohistochemical indicators,follow-up treatment and prognosis.RESULTS:The initial symptoms are diverse.Proptosis is the most frequent chief complaint and the others included vision loss,epiphora,diplopia,and eyelid palpable mass.Results of imaging examination[computed tomography(CT)or magnetic resonance imaging(MRI)]showed orbital mass.In terms of treatment,10 patients received tumor resection,and the mean longest diameter of the tumor was 3.39±1.36 cm.The other 3 patients had optic nerve invaded,so they received orbital exenteration.Pathological examination results confirmed the diagnose of liposarcoma for 13 patients.Six patients displayed as myxoid type,and three patients in each type of dedifferentiated and welldifferentiated type.One patient was verified as pleomorphic,which was a rare type of liposarcoma.All of the patients showed Vimentin positive,and most showed CD34 and S-100 positive.Besides,four patients showed smooth muscle actin positive.All thirteen patients were alive.CONCLUSION:Orbital liposarcoma is a rare disease and it has no specific clinical manifestation.The diagnosis of liposarcoma should be considered when proptosis and orbital mass occurred in orbit.It is recommended to perform pathological examination to achieve early detection and early treatment. 展开更多
关键词 LIPOSARCOMA orbital tumor orbital mass proptosis
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Bilateral scleromalacia perforans and peripheral corneal thinning in Wegener's granulomatosis 被引量:1
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作者 S C Reddy I Tajunisah T Rohana 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2011年第4期439-442,共4页
A rare case of bilateral scleromalacia perforans, bilateral peripheral corneal thinning (contact lens cornea) and unilateral orbital inflammatory disease in a 50 year old female patient with an indolent form Wegener&#... A rare case of bilateral scleromalacia perforans, bilateral peripheral corneal thinning (contact lens cornea) and unilateral orbital inflammatory disease in a 50 year old female patient with an indolent form Wegener's granulomatosis(WG) involving lungs and sinuses is reported. The patient survived for 12 years after the initial diagnosis of systemic disease. There was perforation of left globe following trauma and no perforation of the right globe till the last follow up of the patient. 展开更多
关键词 Wegener's granulomatosis scleromalacia perforans peripheral thinning of cornea proptosis
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Orbital apex syndrome after tooth extraction in an immunocompromised patient
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作者 Suresh Subramaniam Cheong Min Tet +4 位作者 Wan Hazabbah Wan Hitam Adil Hussein Shamim Ahmed Khan Hillol Kanti Pal Zunaina Embong 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2011年第1期112-114,共3页
A 60 year-old man presented with acute on set of left eye proptosis and ptosis. It was associated with poor vision, eye pain and restriction of eye movement of the same eye after 5 hours post left upper molar tooth ex... A 60 year-old man presented with acute on set of left eye proptosis and ptosis. It was associated with poor vision, eye pain and restriction of eye movement of the same eye after 5 hours post left upper molar tooth extraction. The visual acuity in the left eye was hand movement. There was severe ptosis and proptosis of the left eye. The conjunctiva was chemotic with quite anterior chamber. The pupil was mid dilated and sluggished to light. The ocular movement was restricted in all directions. Fundoscopy of the left eye revealed features of central retinal artery occlusion with hyperaemic disc and subretinal exudates at posterior pole. The right eye appeared normal. Urgent MRI brain and orbit revealed severe left paranasal sinusitis with anterior displacement of the left globe and presence orbital abscess. Patient was managed with Otorhinolaryngology and Neurosurgery teams. He underwent emergency transnasal drainage of abscess. Histopathological examination of unhealthy sinus mucosa showed evidence of fungal infection. However, the culture and sensitivity result was inconclusive. Patient was treated with amphotericin B, ceftriaxone, amoxicillin clavulanate and metronidazole. Patient was detected to have high blood sugar level and was managed accordingly. The proptosis improved with treatment. However, his vision, ptosis and ophthalmoplegia remained static. Assessing the immunocompromised status is important for the management of patient presented as acute orbital apex syndrome to avoid fatal outcome. 展开更多
关键词 orbital apex syndrome tooth extraction proptosis PTOSIS OPHTHALMOPLEGIA
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Sinonasal Squamous Papilloma with Orbital Infiltration in an Elderly Nigerian Female, Unusual Presentation of an Uncommon Tumor: A Case Report
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作者 Oyeleye A. Oyelakin Oluyemi Fasina +2 位作者 Clement A. Okolo Funsho J. Akande Onyekwere G. Nworgu 《Case Reports in Clinical Medicine》 2019年第5期134-139,共6页
Squamous papillomas are squamous-derived growths commonly arising from the oral cavity and oropharynx. A 75-year-old woman presented with chronic persistent left nasal obstruction and gradual painless non-axial propto... Squamous papillomas are squamous-derived growths commonly arising from the oral cavity and oropharynx. A 75-year-old woman presented with chronic persistent left nasal obstruction and gradual painless non-axial proptosis with loss of vision in the left eye. Computed tomography scan showed an iso-dense lesion filling the frontal, left ethmoidal and sphenoidal sinuses, and the nasal cavity, with extension into the left orbit. She underwent surgical tumor resection with orbital exenteration and histology revealed features of an aggressive hyperkeratotic squamous papilloma arising from the sino-nasal region. Although squamous papillomas have been natively associated with the oral cavity and oropharynx, they present less frequently as sino-nasal tumors with orbital invasion. 展开更多
关键词 ORBITAL TUMOR Sino-Nasal TUMOR proptosis SQUAMOUS PAPILLOMA
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Aneurysmal Bone Cyst of the Orbit
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作者 Jian-Cang Wang Meng Zhang Xin-Xin Zhao 《Chinese Medical Journal》 SCIE CAS CSCD 2015年第4期562-563,共2页
Aneurysmal bone cyst (ABC) is an uncommon benign lesion with a reported incidence rate of 0.14 cases for every 1,000,000 people.ABC can occur in any part of the skeletal system but is mainly detected in the long bon... Aneurysmal bone cyst (ABC) is an uncommon benign lesion with a reported incidence rate of 0.14 cases for every 1,000,000 people.ABC can occur in any part of the skeletal system but is mainly detected in the long bones.Orbit involvement is rare (〈1% of all ABCs).In this article,we presented two female patients aged 49 and 33 years old respectively who suffered from ABC.After successful surgical removal of the cyst via frontal craniotomy and simple curettage,the patients recovered well and have been in good health throughout the 2.5-4.5 years of follow-up. 展开更多
关键词 Aneurysmal Bone Cyst Cranium Tumors Orbital Tumors proptosis
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