To fit in with the developing requirement of int and communication of protective relays, a protection egrated functions of protection measurement, control measurement and control system based on DeviceNet fieldbus is ...To fit in with the developing requirement of int and communication of protective relays, a protection egrated functions of protection measurement, control measurement and control system based on DeviceNet fieldbus is designed. The communication mechanism of DeviceNet is studied and data trigger modes, communication connection, message types and other key technologies are analyzed. The object modeling and device description of the device are realized too. Results of network test, dynamic simulation and test in the field indicate that this system can accomplish all the communication tasks in real time and can make precise response to every kind of faults of the motor, transformer, line and capacitor. Moreover, this system has higher measurement precision and better control capability.展开更多
Generator control system decides whether the generator can work as usual or not, as well as its stability of performance. Both types of generators control system composed of the transistor and DSP are sensitive to out...Generator control system decides whether the generator can work as usual or not, as well as its stability of performance. Both types of generators control system composed of the transistor and DSP are sensitive to outward electromagnetic interference, directly related to the generator performance. In this text, we first analyze the electromagnetic interference threat generator control system of transistor type may face, then design a electromagnetic protection plan for the intake, the panel and the sense organ. This work is of great significance in improving its electromagnetic protection ability and stability of performance.展开更多
Osteoarthritis(OA)is a prevalent joint disease with no effective treatment strategies.Aberrant mechanical stimuli was demonstrated to be an essential factor for OA pathogenesis.Although multiple studies have detected ...Osteoarthritis(OA)is a prevalent joint disease with no effective treatment strategies.Aberrant mechanical stimuli was demonstrated to be an essential factor for OA pathogenesis.Although multiple studies have detected potential regulatory mechanisms underlying OA and have concentrated on developing novel treatment strategies,the epigenetic control of OA remains unclear.Histone demethylase JMJD3 has been reported to mediate multiple physiological and pathological processes,including cell differentiation,proliferation,autophagy,and apoptosis.However,the regulation of JMJD3 in aberrant force-related OA and its mediatory effect on disease progression are still unknown.In this work,we confirmed the upregulation of JMJD3 in aberrant forceinduced cartilage injury in vitro and in vivo.Functionally,inhibition of JMJD3 by its inhibitor,GSK-J4,or downregulation of JMJD3 by adenovirus infection of sh-JMJD3 could alleviate the aberrant force-induced chondrocyte injury.Mechanistic investigation illustrated that aberrant force induces JMJD3 expression and then demethylates H3K27me3 at the NR4A1 promoter to promote its expression.Further experiments indicated that NR4A1 can regulate chondrocyte apoptosis,cartilage degeneration,extracellular matrix degradation,and inflammatory responses.In vivo,anterior cruciate ligament transection(ACLT)was performed to construct an OA model,and the therapeutic effect of GSK-J4 was validated.More importantly,we adopted a peptide-si RNA nanoplatform to deliver si-JMJD3 into articular cartilage,and the severity of joint degeneration was remarkably mitigated.Taken together,our findings demonstrated that JMJD3 is flow-responsive and epigenetically regulates OA progression.Our work provides evidences for JMJD3 inhibition as an innovative epigenetic therapy approach for joint diseases by utilizing p5RHH-si RNA nanocomplexes.展开更多
A FC-1B type fuzzy controller used to protect collision in automobile running has heen devel-oped by Computer Institute, North Technological University. This facility has been authenticatedby specialists. This is a sc...A FC-1B type fuzzy controller used to protect collision in automobile running has heen devel-oped by Computer Institute, North Technological University. This facility has been authenticatedby specialists. This is a sci-tech fruit which integrates the hardware and software from fuzzy con-trol and artificial intelligence. This technique adopts initiative r-ime ultrasonic range-findingprobe, rapid fuzzy control algorithm, fuzzy discern and fuzzy decision etc. This technique is adapt-展开更多
The AREVA CRAFT (control room accident filtration system) is a solution that maintains the proper air conditions in the main control room and emergency control facilities by filtering the air and removing noble gase...The AREVA CRAFT (control room accident filtration system) is a solution that maintains the proper air conditions in the main control room and emergency control facilities by filtering the air and removing noble gases in case of a severe accident in a nuclear power plant with increased activity concentration in the plant environment.展开更多
In response to the frequent safety accidents of industrial robots, this paper designs and implements a safety detection system for robot control. It can perform real-time security detection of robot operations on indu...In response to the frequent safety accidents of industrial robots, this paper designs and implements a safety detection system for robot control. It can perform real-time security detection of robot operations on industrial production lines to improve the security and reliability of robot control systems. This paper designs and implements a robot control system based Snort-BASE for real-time online detection of DoS attacks. The system uses a six-degree-of-freedom robotic arm as an example, uses Snort to record the network communication data of the robot arm control system in real time, and filters the network traffic through self-defined rules, and then uses the BASE analysis platform to achieve security analysis of the network traffic. The solution verifies the effectiveness of online real-time detection of attacks and visualisation of attack records by designing simulated robotic arm and real robotic arm attack experiments respectively, thus achieving the security of network communication of the robot remote control system.展开更多
On the basis of high precision requirement for input signals in the power system protection and control system,this paper,only for the influence of power system frequency deviation on extracting fundamental harmonic,s...On the basis of high precision requirement for input signals in the power system protection and control system,this paper,only for the influence of power system frequency deviation on extracting fundamental harmonic,studies the amplitude error of Fourier algorithm,presents a method of correcting frequency deviation,and further derives the formulas of improved Fourier algorithm.The simulation results verified the effectiveness of the algorithm,it not only can greatly weaken the influence of frequency deviation,but also increase the precision of the power system protection and control.As a result the study in this paper has practical application value.展开更多
The superconducting magnet of Central Solenoid(CS) model coil of China Fusion Engineering Test Reactor(CFETR) is made of Nb_3Sn/Nb Ti cable-in-conduit conductor(CICC),and operated by forced-flow cooling with a l...The superconducting magnet of Central Solenoid(CS) model coil of China Fusion Engineering Test Reactor(CFETR) is made of Nb_3Sn/Nb Ti cable-in-conduit conductor(CICC),and operated by forced-flow cooling with a large amount of supercritical helium.The cryogenic circulation pump is analyzed and considered to be effective in achieving the supercritical helium(SHe) circulation for the forced-flow cooled(FFC) CICC magnet.A distributed system will be constructed for cooling the CFETR CS model coil.This paper presents the design of FFC process for the CFETR CS model coil.The equipment configuration,quench protection in the magnet and the process control are presented.展开更多
In recent years, a large number of high voltage direct current(HVDC) transmission projects have been connected to AC systems. This has started to have an impact on AC/DC hybrid power grids, particularly receiving term...In recent years, a large number of high voltage direct current(HVDC) transmission projects have been connected to AC systems. This has started to have an impact on AC/DC hybrid power grids, particularly receiving terminal power grids. An HVDC system is a large-scale power electronic integrated nonlinear system, and it includes a primary system and a control and protection system. Hence, the precision and degree of detail of HVDC systems directly affect the actual effect of simulation. In recent years, in the case of the normal operation and failure of AC power grids, the abnormal fluctuation and even locking of HVDC systems caused by the inappropriate strategies of the control and protection system component have strongly affected power grids. This has significantly affected the safety and stability of receiving power grids and normal operation. In this study, the actual engineering HVDC control logic provided by a manufacturer is analyzed and simulated based on the user defined component library of the ADPSS electromagnetic transient calculation program, and an HVDC control model based on an actual system is established. The accuracy of the DC control custom model based on ADPSS is verified through the simulation of an actual power grid.展开更多
With reference to sensor node architectures, we consider the problem of supporting forms of memory protection through a hardware/compiler approach that takes advantage of a low-cost protection circuitry inside the mic...With reference to sensor node architectures, we consider the problem of supporting forms of memory protection through a hardware/compiler approach that takes advantage of a low-cost protection circuitry inside the microcontroller, interposed between the processor and the storage devices. Our design effort complies with the stringent limitations existing in these architectures in terms of hardware complexity, available storage and energy consumption. Rather that precluding deliberately harmful programs from producing their effects, our solution is aimed at limiting the spread of programming errors outside the memory scope of the running program. The discussion evaluates the resulting protection environment from a number of salient viewpoints that include the implementation of common protection paradigms, efficiency in the distribution and revocation of access privileges, and the lack of a privileged (kernel) mode.展开更多
该文基于信息系统物理化的设想提出电力信息物理系统(cyber-physical power system,CPPS)中的信息流建模和计算分析方法。采用连续时间函数来刻画信息流的特征,并定义信息网络运行参数为流量累积函数、信息流速和时延。首先,基于遍历法...该文基于信息系统物理化的设想提出电力信息物理系统(cyber-physical power system,CPPS)中的信息流建模和计算分析方法。采用连续时间函数来刻画信息流的特征,并定义信息网络运行参数为流量累积函数、信息流速和时延。首先,基于遍历法搜索出信息流路径,建立信息流速矩阵的范式;然后利用改进的网络演算(network calculus,NC)特性赋值流速矩阵的元素;进一步采用流量累积函数表征信源数据发送规律,从而显式求解时延上界。最后将提出的信息流建模方法应用于智能变电站自动化系统的时延计算,通过与OPNET的仿真结果相比较,验证所提出模型的有效性,而且该方法可以提供定量分析指标以优化变电站组网方案设计中的信息流分布。展开更多
文摘To fit in with the developing requirement of int and communication of protective relays, a protection egrated functions of protection measurement, control measurement and control system based on DeviceNet fieldbus is designed. The communication mechanism of DeviceNet is studied and data trigger modes, communication connection, message types and other key technologies are analyzed. The object modeling and device description of the device are realized too. Results of network test, dynamic simulation and test in the field indicate that this system can accomplish all the communication tasks in real time and can make precise response to every kind of faults of the motor, transformer, line and capacitor. Moreover, this system has higher measurement precision and better control capability.
文摘Generator control system decides whether the generator can work as usual or not, as well as its stability of performance. Both types of generators control system composed of the transistor and DSP are sensitive to outward electromagnetic interference, directly related to the generator performance. In this text, we first analyze the electromagnetic interference threat generator control system of transistor type may face, then design a electromagnetic protection plan for the intake, the panel and the sense organ. This work is of great significance in improving its electromagnetic protection ability and stability of performance.
基金supported by National Natural Science Foundation of China(11932012,81870790 and 31801233)Science and Technology Commission of Shanghai Municipality(18441903600)+1 种基金Clinical Research Plan of SHDC(No.SHDC2020CR3009A)Innovative Research Team of High-level Local Universities in Shanghai(SSMU-ZDCX20180902)。
文摘Osteoarthritis(OA)is a prevalent joint disease with no effective treatment strategies.Aberrant mechanical stimuli was demonstrated to be an essential factor for OA pathogenesis.Although multiple studies have detected potential regulatory mechanisms underlying OA and have concentrated on developing novel treatment strategies,the epigenetic control of OA remains unclear.Histone demethylase JMJD3 has been reported to mediate multiple physiological and pathological processes,including cell differentiation,proliferation,autophagy,and apoptosis.However,the regulation of JMJD3 in aberrant force-related OA and its mediatory effect on disease progression are still unknown.In this work,we confirmed the upregulation of JMJD3 in aberrant forceinduced cartilage injury in vitro and in vivo.Functionally,inhibition of JMJD3 by its inhibitor,GSK-J4,or downregulation of JMJD3 by adenovirus infection of sh-JMJD3 could alleviate the aberrant force-induced chondrocyte injury.Mechanistic investigation illustrated that aberrant force induces JMJD3 expression and then demethylates H3K27me3 at the NR4A1 promoter to promote its expression.Further experiments indicated that NR4A1 can regulate chondrocyte apoptosis,cartilage degeneration,extracellular matrix degradation,and inflammatory responses.In vivo,anterior cruciate ligament transection(ACLT)was performed to construct an OA model,and the therapeutic effect of GSK-J4 was validated.More importantly,we adopted a peptide-si RNA nanoplatform to deliver si-JMJD3 into articular cartilage,and the severity of joint degeneration was remarkably mitigated.Taken together,our findings demonstrated that JMJD3 is flow-responsive and epigenetically regulates OA progression.Our work provides evidences for JMJD3 inhibition as an innovative epigenetic therapy approach for joint diseases by utilizing p5RHH-si RNA nanocomplexes.
文摘A FC-1B type fuzzy controller used to protect collision in automobile running has heen devel-oped by Computer Institute, North Technological University. This facility has been authenticatedby specialists. This is a sci-tech fruit which integrates the hardware and software from fuzzy con-trol and artificial intelligence. This technique adopts initiative r-ime ultrasonic range-findingprobe, rapid fuzzy control algorithm, fuzzy discern and fuzzy decision etc. This technique is adapt-
文摘The AREVA CRAFT (control room accident filtration system) is a solution that maintains the proper air conditions in the main control room and emergency control facilities by filtering the air and removing noble gases in case of a severe accident in a nuclear power plant with increased activity concentration in the plant environment.
文摘In response to the frequent safety accidents of industrial robots, this paper designs and implements a safety detection system for robot control. It can perform real-time security detection of robot operations on industrial production lines to improve the security and reliability of robot control systems. This paper designs and implements a robot control system based Snort-BASE for real-time online detection of DoS attacks. The system uses a six-degree-of-freedom robotic arm as an example, uses Snort to record the network communication data of the robot arm control system in real time, and filters the network traffic through self-defined rules, and then uses the BASE analysis platform to achieve security analysis of the network traffic. The solution verifies the effectiveness of online real-time detection of attacks and visualisation of attack records by designing simulated robotic arm and real robotic arm attack experiments respectively, thus achieving the security of network communication of the robot remote control system.
文摘On the basis of high precision requirement for input signals in the power system protection and control system,this paper,only for the influence of power system frequency deviation on extracting fundamental harmonic,studies the amplitude error of Fourier algorithm,presents a method of correcting frequency deviation,and further derives the formulas of improved Fourier algorithm.The simulation results verified the effectiveness of the algorithm,it not only can greatly weaken the influence of frequency deviation,but also increase the precision of the power system protection and control.As a result the study in this paper has practical application value.
文摘The superconducting magnet of Central Solenoid(CS) model coil of China Fusion Engineering Test Reactor(CFETR) is made of Nb_3Sn/Nb Ti cable-in-conduit conductor(CICC),and operated by forced-flow cooling with a large amount of supercritical helium.The cryogenic circulation pump is analyzed and considered to be effective in achieving the supercritical helium(SHe) circulation for the forced-flow cooled(FFC) CICC magnet.A distributed system will be constructed for cooling the CFETR CS model coil.This paper presents the design of FFC process for the CFETR CS model coil.The equipment configuration,quench protection in the magnet and the process control are presented.
基金supported by National Key Research and Development Program of China-High performance analysis and situational awareness technology for interconnected power grids
文摘In recent years, a large number of high voltage direct current(HVDC) transmission projects have been connected to AC systems. This has started to have an impact on AC/DC hybrid power grids, particularly receiving terminal power grids. An HVDC system is a large-scale power electronic integrated nonlinear system, and it includes a primary system and a control and protection system. Hence, the precision and degree of detail of HVDC systems directly affect the actual effect of simulation. In recent years, in the case of the normal operation and failure of AC power grids, the abnormal fluctuation and even locking of HVDC systems caused by the inappropriate strategies of the control and protection system component have strongly affected power grids. This has significantly affected the safety and stability of receiving power grids and normal operation. In this study, the actual engineering HVDC control logic provided by a manufacturer is analyzed and simulated based on the user defined component library of the ADPSS electromagnetic transient calculation program, and an HVDC control model based on an actual system is established. The accuracy of the DC control custom model based on ADPSS is verified through the simulation of an actual power grid.
文摘With reference to sensor node architectures, we consider the problem of supporting forms of memory protection through a hardware/compiler approach that takes advantage of a low-cost protection circuitry inside the microcontroller, interposed between the processor and the storage devices. Our design effort complies with the stringent limitations existing in these architectures in terms of hardware complexity, available storage and energy consumption. Rather that precluding deliberately harmful programs from producing their effects, our solution is aimed at limiting the spread of programming errors outside the memory scope of the running program. The discussion evaluates the resulting protection environment from a number of salient viewpoints that include the implementation of common protection paradigms, efficiency in the distribution and revocation of access privileges, and the lack of a privileged (kernel) mode.
文摘该文基于信息系统物理化的设想提出电力信息物理系统(cyber-physical power system,CPPS)中的信息流建模和计算分析方法。采用连续时间函数来刻画信息流的特征,并定义信息网络运行参数为流量累积函数、信息流速和时延。首先,基于遍历法搜索出信息流路径,建立信息流速矩阵的范式;然后利用改进的网络演算(network calculus,NC)特性赋值流速矩阵的元素;进一步采用流量累积函数表征信源数据发送规律,从而显式求解时延上界。最后将提出的信息流建模方法应用于智能变电站自动化系统的时延计算,通过与OPNET的仿真结果相比较,验证所提出模型的有效性,而且该方法可以提供定量分析指标以优化变电站组网方案设计中的信息流分布。