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The future of artificial hibernation medicine:protection of nerves and organs after spinal cord injury 被引量:1
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作者 Caiyun Liu Haixin Yu +4 位作者 Zhengchao Li Shulian Chen Xiaoyin Li Xuyi Chen Bo Chen 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第1期22-28,共7页
Spinal cord injury is a serious disease of the central nervous system involving irreversible nerve injury and various organ system injuries.At present,no effective clinical treatment exists.As one of the artificial hi... Spinal cord injury is a serious disease of the central nervous system involving irreversible nerve injury and various organ system injuries.At present,no effective clinical treatment exists.As one of the artificial hibernation techniques,mild hypothermia has preliminarily confirmed its clinical effect on spinal cord injury.However,its technical defects and barriers,along with serious clinical side effects,restrict its clinical application for spinal cord injury.Artificial hibernation is a futureoriented disruptive technology for human life support.It involves endogenous hibernation inducers and hibernation-related central neuromodulation that activate particular neurons,reduce the central constant temperature setting point,disrupt the normal constant body temperature,make the body adapt"to the external cold environment,and reduce the physiological resistance to cold stimulation.Thus,studying the artificial hibernation mechanism may help develop new treatment strategies more suitable for clinical use than the cooling method of mild hypothermia technology.This review introduces artificial hibernation technologies,including mild hypothermia technology,hibernation inducers,and hibernation-related central neuromodulation technology.It summarizes the relevant research on hypothermia and hibernation for organ and nerve protection.These studies show that artificial hibernation technologies have therapeutic significance on nerve injury after spinal co rd injury through inflammatory inhibition,immunosuppression,oxidative defense,and possible central protection.It also promotes the repair and protection of res pirato ry and digestive,cardiovascular,locomoto r,urinary,and endocrine systems.This review provides new insights for the clinical treatment of nerve and multiple organ protection after spinal cord injury thanks to artificial hibernation.At present,artificial hibernation technology is not mature,and research fa ces various challenges.Neve rtheless,the effort is wo rthwhile for the future development of medicine. 展开更多
关键词 artificial hibernation central thermostatic-resista nt regulation hypothermia multi-system protection neuroprotection organ protection spinal cord injury synthetic torpor
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Network pharmacology and subsequent experimental validation reveal the synergistic myocardial protection mechanism of Salvia miltiorrhiza Bge.and Carthamus tinctorius L. 被引量:1
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作者 Linying Zhong Ling Dong +7 位作者 Jing Sun Jie Yang Zhiying Yu Ping He Bo Zhu Yuxin Zhu Siyuan Li Wenjuan Xu 《Journal of Traditional Chinese Medical Sciences》 CAS 2024年第1期44-54,共11页
Objective:To reveal the molecular mechanism underlying the compatibility of Salvia miltiorrhiza Bge(S.miltiorrhiza,Dan Shen)and C.tinctorius L.(C.tinctorius,Hong Hua)as an herb pair through network pharmacology and su... Objective:To reveal the molecular mechanism underlying the compatibility of Salvia miltiorrhiza Bge(S.miltiorrhiza,Dan Shen)and C.tinctorius L.(C.tinctorius,Hong Hua)as an herb pair through network pharmacology and subsequent experimental validation.Methods:Network pharmacology was applied to construct an active ingredient-efficacy target-disease protein network to reveal the unique regulation pattern of s.miltiorrhiza and C.tinctorius as herb pair.Molecular docking was used to verify the binding of the components of these herbs and their potential targets.An H9c2 glucose hypoxia model was used to evaluate the efficacy of the components and their synergistic effects,which were evaluated using the combination index.Western blot was performed to detect the protein expression of these targets.Results:Network pharmacology analysis revealed 5 pathways and 8 core targets of s.miltiorrhiza and C.tinctorius in myocardial protection.Five of the core targets were enriched in the hypoxia-inducible factor-1(HIF-1)signaling pathway.S.miltiorrhiza-C.tinctorius achieved vascular tone mainly by regulating the target genes of the HIF-1 pathway.As an upstream gene of the HIF-1 pathway,STAT3 can be activated by the active ingredients cryptotanshinone(Ctan),salvianolic acid B(Sal.B),and myricetin(Myric).Cell experiments revealed that Myric,Sal.B,and Ctan also exhibited synergistic myocardial protective activity.Molecular docking verified the strong binding of Myric,Sal.B,and Ctan to STAT3.Western blot further showed that the active ingredients synergistically upregulated the protein expressionof STAT3.Conclusion:The pharmacodynamic transmission analysis revealed that the active ingredients of S.miltiorrhiza and C.tinctorius can synergistically resist ischemia through various targets and pathways.This study provides a methodological reference for interpreting traditional Chinese medicine compatibility. 展开更多
关键词 S.miltiorrhiza-C.tinctorius herb pair Compatibilitymechanism Networkpharmacology Multipletargeteffect Myocardial protection
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Formation and ecological response of sand patches in the protection system of Shapotou section of the Baotou-Lanzhou railway,China
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作者 DUN Yaoquan QU Jianjun +4 位作者 KANG Wenyan LI Minlan LIU Bin WANG Tao SHAO Mei 《Journal of Arid Land》 SCIE CSCD 2024年第2期298-313,共16页
The development of bare patches typically signifies a process of ecosystem degradation.Within the protection system of Shapotou section of the Baotou-Lanzhou railway,the extensive emergence of bare sand patches poses ... The development of bare patches typically signifies a process of ecosystem degradation.Within the protection system of Shapotou section of the Baotou-Lanzhou railway,the extensive emergence of bare sand patches poses a threat to both stability and sustainability.However,there is limited knowledge regarding the morphology,dynamic changes,and ecological responses associated with these sand patches.Therefore,we analyzed the formation and development process of sand patches within the protection system and its effects on herbaceous vegetation growth and soil nutrients through field observation,survey,and indoor analysis methods.The results showed that sand patch development can be divided into three stages,i.e.,formation,expansion,and stabilization,which correspond to the initial,actively developing,and semi-fixed sand patches,respectively.The average dimensions of all sand patch erosional areas were found to be 7.72 m in length,3.91 m in width,and 0.32 m in depth.The actively developing sand patches were the largest,and the initial sand patches were the smallest.Throughout the stage of formation and expansion,the herbaceous community composition changed,and the plant density decreased by more than 50.95%.Moreover,the coverage and height of herbaceous plants decreased in the erosional area and slightly increased in the depositional lobe;and the fine particles and nutrients of soils in the erosional area and depositional lobe showed a decreasing trend.In the stabilization phases of sand patches,the area from the inlet to the bottom of sand patches becomes initially covered with crusts.Vegetation and 0-2 cm surface soil condition improved in the erosional area,but this improvement was not yet evident in the depositional lobe.Factors such as disturbance,climate change,and surface resistance to erosion exert notable influences on the formation and dynamics of sand patches.The results can provide evidence for the future treatment of sand patches and the management of the protection system of Shapotou section of the Baotou-Lanzhou railway. 展开更多
关键词 railway protection system sand patch MORPHOLOGY vegetation characteristic soil property
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Advancements in enhancing corrosion protection of Mg alloys:A comprehensive review on the synergistic effects of combining inhibitors with PEO coating
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作者 Arash Fattah-alhosseini Abdelhameed Fardosi +1 位作者 Minoo Karbasi Mosab Kaseem 《Journal of Magnesium and Alloys》 SCIE EI CAS CSCD 2024年第2期465-489,共25页
Magnesium(Mg)alloys are lightweight materials with excellent mechanical properties,making them attractive for various applications,including aerospace,automotive,and biomedical industries.However,the practical applica... Magnesium(Mg)alloys are lightweight materials with excellent mechanical properties,making them attractive for various applications,including aerospace,automotive,and biomedical industries.However,the practical application of Mg alloys is limited due to their high susceptibility to corrosion.Plasma electrolytic oxidation(PEO),or micro-arc oxidation(MAO),is a coating method that boosts Mg alloys'corrosion resistance.However,despite the benefits of PEO coatings,they can still exhibit certain limitations,such as failing to maintain long-term protection as a result of their inherent porosity.To address these challenges,researchers have suggested the use of inhibitors in combination with PEO coatings on Mg alloys.Inhibitors are chemical compounds that can be incorporated into the coating or applied as a post-treatment to further boost the corrosion resistance of the PEO-coated Mg alloys.Corrosion inhibitors,whether organic or inorganic,can act by forming a protective barrier,hindering the corrosion process,or modifying the surface properties to reduce susceptibility to corrosion.Containers can be made of various materials,including polyelectrolyte shells,layered double hydroxides,polymer shells,and mesoporous inorganic materials.Encapsulating corrosion inhibitors in containers fully compatible with the coating matrix and substrate is a promising approach for their incorporation.Laboratory studies of the combination of inhibitors with PEO coatings on Mg alloys have shown promising results,demonstrating significant corrosion mitigation,extending the service life of Mg alloy components in aggressive environments,and providing self-healing properties.In general,this review presents available information on the incorporation of inhibitors with PEO coatings,which can lead to improved performance of Mg alloy components in demanding environments. 展开更多
关键词 INHIBITOR Mg alloy Self-healing coating Plasma electrolytic oxidation(PEO) Corrosion protection
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Influence of ecological function protection zone on the water conservation in Gansu-Qinghai Contiguous Region of the upper Yellow River
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作者 TONG Huali CHEN Qingbo ZHANG Xuan 《Journal of Mountain Science》 SCIE CSCD 2024年第4期1345-1357,共13页
The implementation of Ecological Function Protection Zone(EFPZ)policy is significant for the ecological restoration and conservation of soil and water in the territory space.This manuscript analyzed and quantified the... The implementation of Ecological Function Protection Zone(EFPZ)policy is significant for the ecological restoration and conservation of soil and water in the territory space.This manuscript analyzed and quantified the impact of EFPZ on the regional water conservation function,based on land use data from 2005,2008,2010,2015 and 2020,by conducting a counterfactual simulation along with the GeoSOS-FLUS model and the InVEST model.The results demonstrate that the delineation of EFPZ can significantly influence the water conservation.(1)From 2010 to 2020,as the EFPZ was implemented,the water conservation in the study area was increasing year by year,with a growth rate of 0.03×10^(8) m^(3)∙a^(-1).On the other hand,the simulated water conservation capacity without the implementation of EFPZ decreased year by year,with a decrease rate of 0.01×10^(8) m^(3)∙a^(-1).(2)The EFPZ accounts for only 23%of the total area,but the contribution rate of water conservation reaches 80%.The actual values of water conservation and average water yield per unit pixel in the EFPZ show an increasing trend both internally and externally,while the counterfactual simulation values exhibit a decreasing trend.(3)The water conservation is much higher within the EFPZ than without EFPZ.The implementation of EFPZ has a significant effect on the improvement of the water conservation capacity in Maqu EFPZ and Yellow River Source EFPZ.The protection effectiveness should be enhanced in Qilian Mountain EFPZ and afforestation activities need to be carefully considered in Loess Plateau EFPZ. 展开更多
关键词 Water conservation function Ecological Function protection Zone Counterfactual simulation Geo SOS-FLUS model InVEST model
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Strategy for Protection of Cultural Heritage Exposed to the Natural and Man-Made Activity Disasters in Serbia
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作者 Mirjana Sladić 《Journal of Civil Engineering and Architecture》 2024年第5期223-235,共13页
Natural disasters and the adverse human activities are the key events in the history of mankind that form our history and shape our collective memory to this day.People on the planet Earth are not obsessed only with n... Natural disasters and the adverse human activities are the key events in the history of mankind that form our history and shape our collective memory to this day.People on the planet Earth are not obsessed only with natural hazards,caused by earthquakes,floods and volcanic eruptions,and troubles unlikely come solely from the action of nature.Disasters threatening the human race can be caused also by people themselves.Both types of disasters cause vast human suffering,at the same time destroying cultural heritage as well,that has the function of determining the identity of social communities.These sufferings should be added to those that can be determined only by in-depth analyses which are derived from the synergy of natural forces and mistaken choices made by the humans,when it comes to their habitat.The proposed strategic plan for protection of built heritage in emergency situations may become the powerful catalyst for the process of revitalization by which the social tissue of community is maintained and restored,creating the symbol of resistance by which it endures each and every natural element and evil men behaviour. 展开更多
关键词 Natural disasters protection cultural heritage hazards
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Spatial Protection and Development of Traditional Mountain Settlements from the Perspective of Self-organization : A Case Study of Anju Ancient Town in Tongliang District, Chongqing
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作者 Xin QU 《Meteorological and Environmental Research》 2024年第1期48-56,共9页
Through literature research, field research and urban design analysis methods, based on the self-organization theory, the evolution characteristics of the settlement space of Anju Ancient Town with significant charact... Through literature research, field research and urban design analysis methods, based on the self-organization theory, the evolution characteristics of the settlement space of Anju Ancient Town with significant characteristics of traditional mountain settlements were analyzed, and then its internal and external influencing factors were summarized. Finally, appropriate protection and development strategies were proposed, such as reasonably planning functional zones, breaking through the single structure, and creating a good living cultural environment. The innovation of this study is that it integrates the self-organization theory into the cognition of traditional mountain settlement space, and discusses the connection between the mountain settlement space and the traditional regional context under the modern development concept, so as to seek the benign protection and reasonable development of traditional mountain settlement space. 展开更多
关键词 Traditional mountain settlements Self-organization theory Spatial characteristics protection and development Anju Ancient Town
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Research on College Network Information Security Protection in the Digital Economy Era
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作者 Libin Zhang 《Proceedings of Business and Economic Studies》 2024年第2期132-137,共6页
In the era of the digital economy,the informatization degree of various industries is getting deeper and deeper,and network information security has also come into people’s eyes.Colleges and universities are in the p... In the era of the digital economy,the informatization degree of various industries is getting deeper and deeper,and network information security has also come into people’s eyes.Colleges and universities are in the position of training applied talents,because of the needs of teaching and education,as well as the requirements of teaching reform,the information construction of colleges and universities has been gradually improved,but the problem of network information security is also worth causing people to ponder.The low security of the network environment will cause college network information security leaks,and even hackers will attack the official website of the university and leak the personal information of teachers and students.To solve such problems,this paper studies the protection of college network information security against the background of the digital economy era.This paper first analyzes the significance of network information security protection,then points out the current and moral problems,and finally puts forward specific countermeasures,hoping to create a safe learning environment for teachers and students for reference. 展开更多
关键词 Digital economy Universities and colleges Network information security protection status COUNTERMEASURES
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Research on Network Security Level Protection Measurement Strategy in the Context of Cloud Platforms
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作者 Lin Ma 《Journal of Electronic Research and Application》 2024年第3期221-229,共9页
Platforms facilitate information exchange,streamline resources,and reduce production and management costs for companies.However,some viral information may invade and steal company resources,or lead to information leak... Platforms facilitate information exchange,streamline resources,and reduce production and management costs for companies.However,some viral information may invade and steal company resources,or lead to information leakage.For this reason,this paper discusses the standards for cybersecurity protection,examines the current state of cybersecurity management and the risks faced by cloud platforms,expands the time and space for training on cloud platforms,and provides recommendations for measuring the level of cybersecurity protection within cloud platforms in order to build a solid foundation for them. 展开更多
关键词 Cloud platform Cyber security Level protection measurement
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Self-actuating protection mechanisms for safer lithium-ion batteries
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作者 Yang Luo Chunchun Sang +3 位作者 Kehan Le Hao Chen Hui Li Xinping Ai 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2024年第7期181-198,共18页
Safety issue is still a problem nowadays for the large-scale application of lithium-ion batteries(LIBs)in electric vehicles and energy storage stations.The unsafe behaviors of LIBs arise from the thermal run-away,whic... Safety issue is still a problem nowadays for the large-scale application of lithium-ion batteries(LIBs)in electric vehicles and energy storage stations.The unsafe behaviors of LIBs arise from the thermal run-away,which is intrinsically triggered by the overcharging and overheating.To improve the safety of LIBs,various protection strategies based on self-actuating reaction control mechanisms(SRCMs)have been proposed,including redox shuttle,polymerizable monomer additive,potential-sensitive separator,thermal shutdown separator,positive-temperature-coefficient electrode,thermally polymerizable addi-tive,and reversible thermal phase transition electrolyte.As build-in protection mechanisms,these meth-ods can sensitively detect either the temperature change inside battery or the potential change of the electrode,and spontaneously shut down the electrode reaction at risky conditions,thus preventing the battery from going into thermal runaway.Given their advantages in enhancing the intrinsic safety of LIBs,this paper overviews the research progresses of SRCMs after a brief introduction of thermal runaway mechanism and limitations of conventional thermal runaway mitigating measures.More importantly,the current states and issues,key challenges,and future developing trends of SRCTs are also discussed and outlined from the viewpoint of practical application,aiming at providing insights and guidance for developing more effective SRCMs for LIBs. 展开更多
关键词 Li-ion battery SAFETY thermal runaway thermal protection Overcharge protection
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Authenticated Digital Currency Redaction with Stronger Privacy and Usability
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作者 Tang Yongli Li Ying +2 位作者 Zhao Zongqu Li Yuanhong Guo Rui 《China Communications》 SCIE CSCD 2024年第6期219-236,共18页
With the promotion of digital currency,how to effectively solve the authenticity,privacy and usability of digital currency issuance has been a key problem.Redactable signature scheme(RSS)can provide the verification o... With the promotion of digital currency,how to effectively solve the authenticity,privacy and usability of digital currency issuance has been a key problem.Redactable signature scheme(RSS)can provide the verification of the integrity and source of the generated sub-documents and solve the privacy problem in digital currency by removing blocks from the signed documents.Unfortunately,it has not realized the consolidation of signed documents,which can not solve the problem of merging two digital currencies.Now,we introduce the concept of weight based on the threshold secret sharing scheme(TSSS)and present a redactable signature scheme with merge algorithm(RSS-MA)using the quasi-commutative accumulator.Our scheme can reduce the communication overhead by utilizing the merge algorithm when transmitting multiple digital currency signatures.Furthermore,this can effectively hide the scale of users’private monetary assets and the number of transactions between users.While meeting the three properties of digital currency issuance,in order to ensure the availability of digital currency after redacting,editors shall not remove the relevant identification information block form digital currency.Finally,our security proof and the analysis of efficiency show that RSS-MA greatly improves the communication and computation efficiency when transmitting multiple signatures. 展开更多
关键词 authenticity verification digital currency privacy protection RSS-MA TSSS USABILITY
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Antibodies elicited by Newcastle disease virus-vectored H7N9 avian influenza vaccine are functional in activating the complement system
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作者 Zenglei Hu Ya Huang +3 位作者 Jiao Hu Xiaoquan Wang Shunlin Hu Xiufan Liu 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2024年第6期2052-2064,共13页
H7N9 subtype avian influenza virus poses a great challenge for poultry industry.Newcastle disease virus(NDV)-vectored H7N9 avian influenza vaccines(NDV_(vec)H7N9)are effective in disease control because they are prote... H7N9 subtype avian influenza virus poses a great challenge for poultry industry.Newcastle disease virus(NDV)-vectored H7N9 avian influenza vaccines(NDV_(vec)H7N9)are effective in disease control because they are protective and allow mass administration.Of note,these vaccines elicit undetectable H7N9-specific hemagglutination-inhibition(HI)but high IgG antibodies in chickens.However,the molecular basis and protective mechanism underlying this particular antibody immunity remain unclear.Herein,immunization with an NDV_(vec)H7N9 induced low anti-H7N9 HI and virus neutralization titers but high levels of hemagglutinin(HA)-binding IgG antibodies in chickens.Three residues(S150,G151 and S152)in HA of H7N9 virus were identified as the dominant epitopes recognized by the NDV_(vec)H7N9 immune serum.Passively transferred NDV_(vec)H7N9 immune serum conferred complete protection against H7N9 virus infection in chickens.The NDV_(vec)H7N9 immune serum can mediate a potent lysis of HA-expressing and H7N9 virus-infected cells and significantly suppress H7N9 virus infectivity.These activities of the serum were significantly impaired after heat-inactivation or treatment with complement inhibitor,suggesting the engagement of the complement system.Moreover,mutations in the 150-SGS-152 sites in HA resulted in significant reductions in cell lysis and virus neutralization mediated by the NDV_(vec)H7N9 immune serum,indicating the requirement of antibody-antigen binding for complement activity.Therefore,antibodies induced by the NDV_(vec)H7N9 can activate antibody-dependent complement-mediated lysis of H7N9 virus-infected cells and complement-mediated neutralization of H7N9 virus.Our findings unveiled a novel role of the complement in protection conferred by the NDV_(vec)H7N9,highlighting a potential benefit of engaging the complement system in H7N9 vaccine design. 展开更多
关键词 H7N9 subtype avian influenza virus NDV vector vaccine antibody immunity COMPLEMENT protection
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Chemical modification of barite for improving the performance of weighting materials for water-based drilling fluids
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作者 Li-Li Yang Ze-Yu Liu +3 位作者 Shi-bo Wang Xian-Bo He Guan-Cheng Jiang Jie Zhang 《Petroleum Science》 SCIE EI CAS CSCD 2024年第1期551-566,共16页
With increasing drilling depth and large dosage of weighting materials,drilling fluids with high solid content are characterized by poor stability,high viscosity,large water loss,and thick mud cake,easier leading to r... With increasing drilling depth and large dosage of weighting materials,drilling fluids with high solid content are characterized by poor stability,high viscosity,large water loss,and thick mud cake,easier leading to reservoir damage and wellbore instability.In this paper,micronized barite(MB)was modified(mMB)by grafting with hydrophilic polymer onto the surface through the free radical polymerization to displace conventional API barite partly.The suspension stability of water-based drilling fluids(WBDFs)weighted with API barite:mMB=2:1 in 600 g was significantly enhanced compared with that with API barite/WBDFs,exhibiting the static sag factor within 0.54 and the whole stability index of 2.The viscosity and yield point reached the minimum,with a reduction of more than 40%compared with API barite only at the same density.Through multi-stage filling and dense accumulation of weighting materials and clays,filtration loss was decreased,mud cake quality was improved,and simultaneously it had great reservoir protection performance,and the permeability recovery rate reached 87%.In addition,it also effectively improved the lubricity of WBDFs.The sticking coefficient of mud cake was reduced by 53.4%,and the friction coefficient was 0.2603.Therefore,mMB can serve as a versatile additive to control the density,rheology,filtration,and stability of WBDFs weighted with API barite,thus regulating comprehensive performance and achieving reservoir protection capacity.This work opened up a new path for the productive drilling of extremely deep and intricate wells by providing an efficient method for managing the performance of high-density WBDFs. 展开更多
关键词 Drilling fluids Weighting materials Filtration control Reservoir protection Stability property
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Redundant Data Detection and Deletion to Meet Privacy Protection Requirements in Blockchain-Based Edge Computing Environment
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作者 Zhang Lejun Peng Minghui +6 位作者 Su Shen Wang Weizheng Jin Zilong Su Yansen Chen Huiling Guo Ran Sergey Gataullin 《China Communications》 SCIE CSCD 2024年第3期149-159,共11页
With the rapid development of information technology,IoT devices play a huge role in physiological health data detection.The exponential growth of medical data requires us to reasonably allocate storage space for clou... With the rapid development of information technology,IoT devices play a huge role in physiological health data detection.The exponential growth of medical data requires us to reasonably allocate storage space for cloud servers and edge nodes.The storage capacity of edge nodes close to users is limited.We should store hotspot data in edge nodes as much as possible,so as to ensure response timeliness and access hit rate;However,the current scheme cannot guarantee that every sub-message in a complete data stored by the edge node meets the requirements of hot data;How to complete the detection and deletion of redundant data in edge nodes under the premise of protecting user privacy and data dynamic integrity has become a challenging problem.Our paper proposes a redundant data detection method that meets the privacy protection requirements.By scanning the cipher text,it is determined whether each sub-message of the data in the edge node meets the requirements of the hot data.It has the same effect as zero-knowledge proof,and it will not reveal the privacy of users.In addition,for redundant sub-data that does not meet the requirements of hot data,our paper proposes a redundant data deletion scheme that meets the dynamic integrity of the data.We use Content Extraction Signature(CES)to generate the remaining hot data signature after the redundant data is deleted.The feasibility of the scheme is proved through safety analysis and efficiency analysis. 展开更多
关键词 blockchain data integrity edge computing privacy protection redundant data
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Problem identification and revitalization strategies for the recovery and reconstruction of traditional villages in the Ms 6.8 Luding Earthquake
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作者 HUANG Chao QIU Jian +3 位作者 LIU Chun JIANG Rui ZHAO Chuanrong ZHANG Yi 《Journal of Mountain Science》 SCIE CSCD 2024年第2期361-379,共19页
Post-disaster reconstruction is a topic of global concern,and traditional villages have special heritage attributes and need to face more requirements and obstacles in post-disaster reconstruction.This paper summarize... Post-disaster reconstruction is a topic of global concern,and traditional villages have special heritage attributes and need to face more requirements and obstacles in post-disaster reconstruction.This paper summarizes four concepts based on the research on post-disaster reconstruction both domestically and internationally,as well as the recovery and reconstruction of cultural heritage.Through a field survey of traditional villages in the Ms 6.8 Luding earthquake-stricken area,it is found that there are problems such as insufficient awareness of heritage value,misalignment of scientific reconstruction technology,and insufficient protection of reconstruction elements during the reconstruction process.Traditional villages face the risk of declining or even loss of heritage value.In order to effectively protect traditional villages and inherit the carrier of regional culture,four targeted reconstruction response strategies are proposed,i.e.,to"establish special planning for traditional village preservation","emphasize recovery of the authenticity of village heritage","ensure elements for village heritage recovery"and"promote the activation and utilization of village heritage",based on the problems discovered during the survey and the four concepts summarized in the research on post-disaster reconstruction of traditional villages.The research results hope to provide useful reference for ancient cultural areas affected by earthquakes on how to protect cultural heritage during the post-disaster reconstruction process. 展开更多
关键词 Seismic hazard Decision making Traditional village Cultural heritage protection Post-earthquake recovery and reconstruction Revitalization strategy
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Changes of coastline and tidal flat and its implication for ecological protection under human activities: Take China’s Bohai Bay as an example
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作者 Yong Li Ming-zheng Wen +3 位作者 Heng Yu Peng Yang Fei-cui Wang Fu Wang 《China Geology》 CAS CSCD 2024年第1期26-35,共10页
The change processes and trends of shoreline and tidal flat forced by human activities are essential issues for the sustainability of coastal area,which is also of great significance for understanding coastal ecologic... The change processes and trends of shoreline and tidal flat forced by human activities are essential issues for the sustainability of coastal area,which is also of great significance for understanding coastal ecological environment changes and even global changes.Based on field measurements,combined with Linear Regression(LR)model and Inverse Distance Weighing(IDW)method,this paper presents detailed analysis on the change history and trend of the shoreline and tidal flat in Bohai Bay.The shoreline faces a high erosion chance under the action of natural factors,while the tidal flat faces a different erosion and deposition patterns in Bohai Bay due to the impact of human activities.The implication of change rule for ecological protection and recovery is also discussed.Measures should be taken to protect the coastal ecological environment.The models used in this paper show a high correlation coefficient between observed and modeling data,which means that this method can be used to predict the changing trend of shoreline and tidal flat.The research results of present study can provide scientific supports for future coastal protection and management. 展开更多
关键词 SHORELINE Tidal flat Erosion deposition patterns Changing trend Ecological protection Human activity Linear regression model Inverse distance weighing method Prediction Bohai Bay
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Formation damage mechanism and control strategy of the compound function of drilling fluid and fracturing fluid in shale reservoirs
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作者 SUN Jinsheng XU Chengyuan +6 位作者 KANG Yili JING Haoran ZHANG Jie YANG Bin YOU Lijun ZHANG Hanshi LONG Yifu 《Petroleum Exploration and Development》 SCIE 2024年第2期430-439,共10页
For the analysis of the formation damage caused by the compound function of drilling fluid and fracturing fluid,the prediction method for dynamic invasion depth of drilling fluid is developed considering the fracture ... For the analysis of the formation damage caused by the compound function of drilling fluid and fracturing fluid,the prediction method for dynamic invasion depth of drilling fluid is developed considering the fracture extension due to shale minerals erosion by oil-based drilling fluid.With the evaluation for the damage of natural and hydraulic fractures caused by mechanical properties weakening of shale fracture surface,fracture closure and rock powder blocking,the formation damage pattern is proposed with consideration of the compound effect of drilling fluid and fracturing fluid.The formation damage mechanism during drilling and completion process in shale reservoir is revealed,and the protection measures are raised.The drilling fluid can deeply invade into the shale formation through natural and induced fractures,erode shale minerals and weaken the mechanical properties of shale during the drilling process.In the process of hydraulic fracturing,the compound effect of drilling fluid and fracturing fluid further weakens the mechanical properties of shale,results in fracture closure and rock powder shedding,and thus induces stress-sensitive damage and solid blocking damage of natural/hydraulic fractures.The damage can yield significant conductivity decrease of fractures,and restrict the high and stable production of shale oil and gas wells.The measures of anti-collapse and anti-blocking to accelerate the drilling of reservoir section,forming chemical membrane to prevent the weakening of the mechanical properties of shale fracture surface,strengthening the plugging of shale fracture and reducing the invasion range of drilling fluid,optimizing fracturing fluid system to protect fracture conductivity are put forward for reservoir protection. 展开更多
关键词 shale oil and gas drilling fluid fracturing fluid stress-sensitive solid blocking formation damage reservoir protection
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Analysis of thermal management and anti-mechanical abuse of multi-functional battery modules based on magneto-sensitive shear thickening fluid
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作者 Yang XIONG Bo LU +1 位作者 Yicheng SONG Junqian ZHANG 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI CSCD 2024年第3期529-542,共14页
Electric vehicles(EVs)have garnered significant attention as a vital driver of economic growth and environmental sustainability.Nevertheless,ensuring the safety of high-energy batteries is now a top priority that cann... Electric vehicles(EVs)have garnered significant attention as a vital driver of economic growth and environmental sustainability.Nevertheless,ensuring the safety of high-energy batteries is now a top priority that cannot be overlooked during large-scale applications.This paper proposes an innovative active protection and cooling integrated battery module using smart materials,magneto-sensitive shear thickening fluid(MSTF),which is specifically designed to address safety threats posed by lithium-ion batteries(LIBs)exposed to harsh mechanical and environmental conditions.The theoretical framework introduces a novel approach for harnessing the smoothed-particle hydrodynamics(SPH)methodology that incorporates the intricate interplay of non-Newtonian fluid behavior,capturing the fluid-structure coupling inherent to the MSTF.This approach is further advanced by adopting an enhanced Herschel-Bulkley(H-B)model to encapsulate the intricate rheology of the MSTF under the influence of the magnetorheological effect(MRE)and shear thickening(ST)behavior.Numerical simulation results show that in the case of cooling,the MSTF is an effective cooling medium for rapidly reducing the temperature.In terms of mechanical abuse,the MSTF solidifies through actively applying the magnetic field during mechanical compression and impact within the battery module,resulting in 66%and 61.7%reductions in the maximum stress within the battery jellyroll,and 31.1%and 23%reductions in the reaction force,respectively.This mechanism effectively lowers the risk of short-circuit failure.The groundbreaking concepts unveiled in this paper for active protection battery modules are anticipated to be a valuable technological breakthrough in the areas of EV safety and lightweight/integrated design. 展开更多
关键词 magneto-sensitive shear thickening fluid(MSTF) battery module impact protection temperature control integrated design
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Multi-Scale Design and Optimization of Composite Material Structure for Heavy-Duty Truck Protection Device
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作者 Yanhui Zhang Lianhua Ma +3 位作者 Hailiang Su Jirong Qin Zhining Chen Kaibiao Deng 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第5期1961-1980,共20页
In this paper,to present a lightweight-developed front underrun protection device(FUPD)for heavy-duty trucks,plain weave carbon fiber reinforced plastic(CFRP)is used instead of the original high-strength steel.First,t... In this paper,to present a lightweight-developed front underrun protection device(FUPD)for heavy-duty trucks,plain weave carbon fiber reinforced plastic(CFRP)is used instead of the original high-strength steel.First,the mechanical and structural properties of plain carbon fiber composite anti-collision beams are comparatively analyzed from a multi-scale perspective.For studying the design capability of carbon fiber composite materials,we investigate the effects of TC-33 carbon fiber diameter(D),fiber yarn width(W)and height(H),and fiber yarn density(N)on the front underrun protective beam of carbon fiber compositematerials.Based on the investigation,a material-structure matching strategy suitable for the front underrun protective beam of heavy-duty trucks is proposed.Next,the composite material structure is optimized by applying size optimization and stack sequence optimization methods to obtain the higher performance carbon fiber composite front underrun protection beam of commercial vehicles.The results show that the fiber yarn height(H)has the greatest influence on the protective beam,and theH1matching scheme for the front underrun protective beamwith a carbon fiber composite structure exhibits superior performance.The proposed method achieves a weight reduction of 55.21% while still meeting regulatory requirements,which demonstrates its remarkable weight reduction effect. 展开更多
关键词 Structural optimization front underrun protection device carbon fiber reinforced plastic multi-scale model lightweight design
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Research on the longitudinal protection of a through-type cophase traction direct power supply system based on the empirical wavelet transform
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作者 Lu Li Zeduan Zhang +5 位作者 Wang Cai Qikang Zhuang Guihong Bi Jian Deng Shilong Chen Xiaorui Kan 《Global Energy Interconnection》 EI CSCD 2024年第2期206-216,共11页
This paper proposes a longitudinal protection scheme utilizing empirical wavelet transform(EWT)for a through-type cophase traction direct power supply system,where both sides of a traction network line exhibit a disti... This paper proposes a longitudinal protection scheme utilizing empirical wavelet transform(EWT)for a through-type cophase traction direct power supply system,where both sides of a traction network line exhibit a distinctive boundary structure.This approach capitalizes on the boundary’s capacity to attenuate the high-frequency component of fault signals,resulting in a variation in the high-frequency transient energy ratio when faults occur inside or outside the line.During internal line faults,the high-frequency transient energy at the checkpoints located at both ends surpasses that of its neighboring lines.Conversely,for faults external to the line,the energy is lower compared to adjacent lines.EWT is employed to decompose the collected fault current signals,allowing access to the high-frequency transient energy.The longitudinal protection for the traction network line is established based on disparities between both ends of the traction network line and the high-frequency transient energy on either side of the boundary.Moreover,simulation verification through experimental results demonstrates the effectiveness of the proposed protection scheme across various initial fault angles,distances to faults,and fault transition resistances. 展开更多
关键词 Through-type Cophase traction direct power supply system Traction network Empirical wavelet transform(EWT) Longitudinal protection
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