BACKGROUND Schwannoma is a rare benign,encapsulated tumor of the nerve sheath under the tongue,mostly occurring as solitary tumors with classical histological pattern and several common morphological variants.To our k...BACKGROUND Schwannoma is a rare benign,encapsulated tumor of the nerve sheath under the tongue,mostly occurring as solitary tumors with classical histological pattern and several common morphological variants.To our knowledge,multiple schwannomas with pseudoglandular element synchronously occurring under the tongue are rare;we report herein the first such case.CASE SUMMARY A 53-year-old man had first noticed an isolated asymptomatic mass under the tongue,and as the mass grew,the tongue was elevated.Physical examination showed multiple oval neoplasms,and the overlying mucosa was normal.Computed tomography showed three low-density oval neoplasms under the tongue,which were cystic-solid with unclear boundary.The patient has no cutaneous tumors,VIII nerve tumors,or lens opacities and no history of neurofibromatosis 2 or confirmed schwannomatosis in any first-degree relative.Magnetic resonance imaging showed no evidence of vestibular schwannoma.The preoperative diagnosis was mucoepidermoid carcinoma.During hospitalization,all neoplasms were completely excised by surgeons through an intraoral approach under general anesthesia.The diagnosis of the multiple schwannomas with pseudoglandular element was made by histopathology after surgery.At the 15-mo follow-up visit,the patient had no sign of recurrence or development of other peripheral nerve tumors.CONCLUSION Although rare,multiple schwannomas with pseudoglandular element do exist in patients presenting with masses under the tongue.Oral surgeons should be aware of the existence of multiple schwannomas with pseudoglandular element when considering masses under the tongue due to the different prognosis between multiple schwannomas with pseudoglandular element and mucoepidermoid carcinoma.展开更多
BACKGROUND Spermatocytic tumor is a rare,malignant neoplasm of the testes.Since the prognosis for this tumor type is favorable,accurate diagnosis and differentiation from other malignant testicular neoplasms(classic s...BACKGROUND Spermatocytic tumor is a rare,malignant neoplasm of the testes.Since the prognosis for this tumor type is favorable,accurate diagnosis and differentiation from other malignant testicular neoplasms(classic seminoma and lymphoma)are crucial.To add to the existing literature on the diagnosis of spermatocytic tumor,herein we report the detailed clinical and histopathologic findings for a case that we encountered.CASE SUMMARY A 60-year-old Chinese man presented with a solid mass in the right scrotum.The mass was surgically removed and spermatocytic tumor was diagnosed.On microscopy,the tumor cells displayed an unusual arrangement in lobules,presenting a pseudo-glandular appearance.To summarize and compare the diagnostic features of this tumor and those of the differential diagnoses,we report our case findings and those mentioned in the literature for various testicular tumors.Although imaging methods can detect masses early in development,their diagnostic capabilities are limited.Biopsy,histopathology,and immunohistochemistry are necessary for confirmatory diagnosis.CONCLUSION It is important to identify and review the key diagnostic features of spermatocytic tumor.展开更多
基金Supported by Basic Clinical Fund Project of The Fist Hospital of Lanzhou University,No.ldyyyn2015-04.
文摘BACKGROUND Schwannoma is a rare benign,encapsulated tumor of the nerve sheath under the tongue,mostly occurring as solitary tumors with classical histological pattern and several common morphological variants.To our knowledge,multiple schwannomas with pseudoglandular element synchronously occurring under the tongue are rare;we report herein the first such case.CASE SUMMARY A 53-year-old man had first noticed an isolated asymptomatic mass under the tongue,and as the mass grew,the tongue was elevated.Physical examination showed multiple oval neoplasms,and the overlying mucosa was normal.Computed tomography showed three low-density oval neoplasms under the tongue,which were cystic-solid with unclear boundary.The patient has no cutaneous tumors,VIII nerve tumors,or lens opacities and no history of neurofibromatosis 2 or confirmed schwannomatosis in any first-degree relative.Magnetic resonance imaging showed no evidence of vestibular schwannoma.The preoperative diagnosis was mucoepidermoid carcinoma.During hospitalization,all neoplasms were completely excised by surgeons through an intraoral approach under general anesthesia.The diagnosis of the multiple schwannomas with pseudoglandular element was made by histopathology after surgery.At the 15-mo follow-up visit,the patient had no sign of recurrence or development of other peripheral nerve tumors.CONCLUSION Although rare,multiple schwannomas with pseudoglandular element do exist in patients presenting with masses under the tongue.Oral surgeons should be aware of the existence of multiple schwannomas with pseudoglandular element when considering masses under the tongue due to the different prognosis between multiple schwannomas with pseudoglandular element and mucoepidermoid carcinoma.
文摘BACKGROUND Spermatocytic tumor is a rare,malignant neoplasm of the testes.Since the prognosis for this tumor type is favorable,accurate diagnosis and differentiation from other malignant testicular neoplasms(classic seminoma and lymphoma)are crucial.To add to the existing literature on the diagnosis of spermatocytic tumor,herein we report the detailed clinical and histopathologic findings for a case that we encountered.CASE SUMMARY A 60-year-old Chinese man presented with a solid mass in the right scrotum.The mass was surgically removed and spermatocytic tumor was diagnosed.On microscopy,the tumor cells displayed an unusual arrangement in lobules,presenting a pseudo-glandular appearance.To summarize and compare the diagnostic features of this tumor and those of the differential diagnoses,we report our case findings and those mentioned in the literature for various testicular tumors.Although imaging methods can detect masses early in development,their diagnostic capabilities are limited.Biopsy,histopathology,and immunohistochemistry are necessary for confirmatory diagnosis.CONCLUSION It is important to identify and review the key diagnostic features of spermatocytic tumor.
