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The Occurrence and Prevention of Filamentous Algae in Ecological Purification System of Micro-polluted Water
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作者 CANG Ji-jun ZUO Zhuo +2 位作者 GUO Xiao ZHU Xue-dan ZHAO Jin-geng 《Meteorological and Environmental Research》 CAS 2012年第1期66-68,共3页
[ Objective ] The aim was to study the influence of filamentous algae on the process of water ecological purification. [ Method ] The occurrence mechanism of filamentous algae and its ecological system were summarized... [ Objective ] The aim was to study the influence of filamentous algae on the process of water ecological purification. [ Method ] The occurrence mechanism of filamentous algae and its ecological system were summarized and analyzed. Considering the ecological purification in north- ern Jiangsu, the occurrence and prevention of filamentous algae in water, the method to prevent filamentous algae in polluted water was discussed. [ Result] The results showed that by measures of improving planting density, regular harvesting, and water flow state control before the filamentous algae blooming period, together with improving local pH value, light interference and ecological control during the blooming period, can effectively control the filamentous algae blooming. [ Condusion] The study of the happening mechanism of filamentous algae provided theoretical references and the technical basis in the work of filamentous algae prevention and control. 展开更多
关键词 Water source Micro-polluted water Ecological purification system LICHEN Filamentous algae Prevention and control China
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High-Efficiency Wastewater Purification System Based on Coupled Photoelectric–Catalytic Action Provided by Triboelectric Nanogenerator 被引量:1
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作者 Shen Shen Jiajia Fu +8 位作者 Jia Yi Liyun Ma Feifan Sheng Chengyu Li Tingting Wang Chuan Ning Hongbo Wang Kai Dong Zhong Lin Wang 《Nano-Micro Letters》 SCIE EI CAS CSCD 2021年第12期95-108,共14页
It is of great importance to explore a creative route to improve the degradation e ciency of organic pollutants in wastewater.Herein,we construct a unique hybrid system by combining self-powered triboelectric nanogene... It is of great importance to explore a creative route to improve the degradation e ciency of organic pollutants in wastewater.Herein,we construct a unique hybrid system by combining self-powered triboelectric nanogenerator(TENG)with carbon dots-TiO_(2)sheets doped three-dimensional graphene oxide photocatalyst(3 DGA@CDs-TNs),which can significantly enhance the degradation e ciency of brilliant green(BG)and direct blue 5 B(DB)owing to the powerful interaction of TENG and 3 DGA@CDs-TNs photocatalyst.The power output of TENG can be applied for wastewater purification directly,which exhibits a selfpowered electrocatalytic technology.Furthermore,the results also verify that TENG can replace conventional electric catalyst to remove pollutants e ectively from wastewater without any consumption.Subsequently,the unstable fragments and the plausible removal pathways of the two pollutants are proposed.Our work sheds light on the development of e cient and sustainable TENG/photocatalyst system,opening up new opportunities and possibilities for comprehensive utilization of random energy. 展开更多
关键词 Triboelectric nanogenerators SELF-POWERED 3DGA@CDs-TNs photocatalyst Hybrid system Wastewater purification
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Comparison of Optimization Schemes for the Flue Gas Purification System of a Garbage Incineration Power Plant 被引量:3
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作者 Wu Yuefeng 《Meteorological and Environmental Research》 CAS 2018年第2期58-61,66,共5页
A garbage incineration power plant is proposed to be built somewhere. Due to local environmental capacity and local policy,the demand on the flue gas emission indicators of the project is high,but the conventional pur... A garbage incineration power plant is proposed to be built somewhere. Due to local environmental capacity and local policy,the demand on the flue gas emission indicators of the project is high,but the conventional purification process of flue gas produced during waste incineration( SNCR denitrification +dry/semi-dry deacidification + adsorption of dioxins and heavy metals by activated carbon + bag dusting) has been unable to meet this requirement,and the newly added wet deacidification and SCR denitrification processes can meet this requirement. The flue gas purification process was optimized,and two feasible schemes were compared to choose the better one. 展开更多
关键词 Garage incineration power plant Flue gas purification Optimization of schemes
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Simulation study of the purification system for indoor oil mist control in machining factories
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作者 Yukun Wang Yu Guo +2 位作者 Wenjia Hao Wei Liu Zhengwei Long 《Building Simulation》 SCIE EI CSCD 2023年第8期1361-1374,共14页
High-concentration oil mists can cause serious health problems to workers,which are generally mitigated by ventilation and purification systems.However,the coupling relationship between these systems is not clear.In t... High-concentration oil mists can cause serious health problems to workers,which are generally mitigated by ventilation and purification systems.However,the coupling relationship between these systems is not clear.In this study,the effects of purifier outlet direction,purification air volume,installation height,and purification efficiency on indoor oil mist distribution were investigated by numerical simulation using an actual machining factory.The mitigation of oil mist in various combinations of ventilation and purification systems was also discussed.The results show that the outlet direction of the purifier has a great influence on the distribution of oil mist in the factory,and the maximum difference of oil mist concentration in the breathing zone under different orientations is 17%.The best purifier outlet direction is vertically upward.When the purifier outlet direction is upward,a larger purification air volume is beneficial for contaminant removal,and a lower purifier exhaust installation height is helpful for oil mist discharge from the bottom of the factory and reducing the concentration of oil mist in the breathing area.The oil mist concentration of purifier exhaust increases from 0 to 2 mg/m^(3) and the oil mist concentration in the breathing zone increases by 67%.The combined system of purification system with the roof exhaust system and displacement ventilation system has the optimal pollution removal efficiency and the lowest concentration of oil mist in the breathing zone compared to other systems.The research results can provide a reference for the design,installation,and operation of ventilation and purification systems in machining factories. 展开更多
关键词 oil particulate matter purification system ventilation system indoor air quality CFD
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Faithful and efficient hyperentanglement purification for spatial-polarization-time-bin photon system
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作者 杜芳芳 樊钢 +1 位作者 吴一鸣 任宝藏 《Chinese Physics B》 SCIE EI CAS CSCD 2023年第6期140-150,共11页
We present a faithful and efficient hyperentanglement purification protocol(hyper-EPP)for nonlocal two-photon systems in spatial-polarization-time-bin hyperentangled Bell states.As the single-photon detectors can dete... We present a faithful and efficient hyperentanglement purification protocol(hyper-EPP)for nonlocal two-photon systems in spatial-polarization-time-bin hyperentangled Bell states.As the single-photon detectors can detect and herald the undesirable properties caused by side leakage and finite coupling strength,the parity-check gates and swap gates of our hyper-EPP in the spatial,polarization and time-bin mode degrees of freedom(DoFs)work faithfully.The qubit-flip errors in photon systems in three DoFs can be corrected effectively with the faithful parity-check gates and the photon pairs can be reused to distill high-fidelity ones by introducing the faithful swap gates,which greatly increases the efficiency of our hyper-EPP.Further,the maximal hyperentanglement can be obtained in principle by operating multiple rounds of the hyper-EPP. 展开更多
关键词 quantum communication hyperentanglement purification photon system multiple degrees of freedom
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Wettability,reactivity,and interface structure in Mg/Ni system
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作者 S.Terlicka N.Sobczak +2 位作者 Ł.Maj P.Darłak J.J.Sobczak 《Journal of Magnesium and Alloys》 SCIE EI CAS CSCD 2024年第2期659-672,共14页
The sessile drop method was applied to the experimental investigation of the wetting and spreading behaviors of liquid Mg drops on pure Ni substrates.For comparison,the experiments were performed in two variants:(1)us... The sessile drop method was applied to the experimental investigation of the wetting and spreading behaviors of liquid Mg drops on pure Ni substrates.For comparison,the experiments were performed in two variants:(1)using the Capillary Purification(CP)procedure,which allows the non-contact heating and squeezing of a pure oxide-free Mg drop;(2)by classical Contact Heating(CH)procedure.The high-temperature tests were performed under isothermal conditions(CP:760℃for 30 s;CH:715℃for 300 s)using Ar+5 wt%H_(2) atmosphere.During the sessile drop tests,images of the Mg/Ni couples were recorded by CCD cameras(57 fps),which were then applied to calculate the contact angles of metal/substrate couples.Scanning and transmission electron microscopy analyses,both coupled with energy-dispersive X-ray spectroscopy,were used for detailed structural characterization of the solidified couples.It was found that an oxide-free Mg drop obtained by the CP procedure showed a wetting phenomenon on the Ni substrate(an average contact angleθ<90°in<1 s),followed by fast spreading and good wetting over the Ni substrate(θ_((CP))~20°in 5 s)to form a final contact angle ofθ_(f(CP))~18°.In contrast,a different wetting behavior was observed for the CH procedure,where the unavoidable primary oxide film on the Mg surface blocked the spreading of liquid Mg showing apparently non-wetting behavior after 300 s contact at the test temperature.However,in both cases,the deep craters formed in the Ni substrates under the Mg drops and significant change in the structure of initially pure Mg drops to Mg-Ni alloys suggest a strong dissolution of Ni in liquid Mg and apparent values of the final contact angles measured for the Mg/Ni system. 展开更多
关键词 Magnesium-based alloys Sessile drop tests Capillary purification procedure WETTABILITY REACTIVITY Contact angle
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Purification of copper foils driven by single crystallization
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作者 寇金宗 赵孟泽 +10 位作者 李兴光 何梦林 杨方友 刘科海 成庆秋 任云龙 刘灿 付莹 吴慕鸿 刘开辉 王恩哥 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第2期506-511,共6页
High-purity copper(Cu) with excellent thermal and electrical conductivity, is crucial in modern technological applications, including heat exchangers, integrated circuits, and superconducting magnets. The current puri... High-purity copper(Cu) with excellent thermal and electrical conductivity, is crucial in modern technological applications, including heat exchangers, integrated circuits, and superconducting magnets. The current purification process is mainly based on the zone/electrolytic refining or anion exchange, however, which excessively relies on specific integrated equipment with ultra-high vacuum or chemical solution environment, and is also bothered by external contaminants and energy consumption. Here we report a simple approach to purify the Cu foils from 99.9%(3N) to 99.99%(4N) by a temperature-gradient thermal annealing technique, accompanied by the kinetic evolution of single crystallization of Cu.The success of purification mainly relies on(i) the segregation of elements with low effective distribution coefficient driven by grain-boundary movements and(ii) the high-temperature evaporation of elements with high saturated vapor pressure.The purified Cu foils display higher flexibility(elongation of 70%) and electrical conductivity(104% IACS) than that of the original commercial rolled Cu foils(elongation of 10%, electrical conductivity of ~ 100% IACS). Our results provide an effective strategy to optimize the as-produced metal medium, and therefore will facilitate the potential applications of Cu foils in precision electronic products and high-frequency printed circuit boards. 展开更多
关键词 purification copper foil thermal annealing technique single crystallization
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Superwetting Ag/α-Fe_(2)O_(3) anchored mesh with enhanced photocatalytic and antibacterial activities for efficient water purification
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作者 Jiakai Li Changpeng Lv +5 位作者 Jiajia Song Xiaoling Zhang Xizhen Huang Yingzhuo Ma Haijie Cao Na Liu 《Green Energy & Environment》 SCIE EI CAS CSCD 2024年第1期89-103,共15页
Superwetting materials have drawn unprecedented attention in the treatment of oily wastewater due to their preferable anti-fouling property and selective oil/water separation.However,it is still a challenge to fabrica... Superwetting materials have drawn unprecedented attention in the treatment of oily wastewater due to their preferable anti-fouling property and selective oil/water separation.However,it is still a challenge to fabricate multifunctional and environmentally friendly materials,which can be stably applied to purify the actual complicated wastewater.Here,a Ag/Ag/α-Fe_(2)O_(3) heterostructure anchored copper mesh was intentionally synthesized using a facile two-step hydrothermal method.The resultant mesh with superhydrophilicity and underwater superoleophobicity was capable of separating various oil/water mixtures with superior separation efficiency and high permeationflux driven by gravity.Benefiting from the joint effects of the smaller band gap of Ag/α-Fe_(2)O_(3) heterojunction,inherent antibacterial capacity of Ag/α-Fe_(2)O_(3) and Ag nanoparticles,favorable conductive substrate,as well as the hierarchical structure with superwettability,such mesh presented remarkably enhanced degradation capability toward organic dyes under visible light irradiation and antibacterial activity against both Escherichia coli(E.coli)and Staphylococcus aureus(S.aureus)compared with the pure Ag/α-Fe_(2)O_(3) coated mesh.Impressively,the mesh exhibited bifunctional water purification performance,in which organic dyes were eliminated simultaneously from water during oil/water separation in onefiltration process.More importantly,this mesh behaved exceptional chemical resistance,mechanical stability and long-term reusability.Therefore,this material with multifunctional integration may hold promising potential for steady water purification in practice. 展开更多
关键词 Superwetting Ag/α-Fe_(2)O_(3)heterostructure Enhanced photocatalytic and antibacterial activities Water purification Long-term reusability
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Research Progress on Purification Process, Content Determination and Pharmacological Action of Atractylodin
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作者 Xin SUN Jingwen WANG +1 位作者 Yang XI Chenghao JIN 《Asian Agricultural Research》 2024年第3期33-35,40,共4页
Atractylodis Rhizoma comes from the dry rhizome of Atractylis lancea or Atractylodes chinensis in the Compositae family,and it is suitable for preventing and treating diseases such as cold,edema,night blindness and rh... Atractylodis Rhizoma comes from the dry rhizome of Atractylis lancea or Atractylodes chinensis in the Compositae family,and it is suitable for preventing and treating diseases such as cold,edema,night blindness and rheumatic arthralgia.Atractylodin is the main active component extracted and isolated from Atractylodis Rhizoma.A large number of studies have found that atractylodin has excellent drug activity in improving gastrointestinal emptying,anti-inflammation,inhibiting malignant tumor and reducing blood lipid.In this paper,the purification process and pharmacological activity of Atractylodin were summarized to provide a theoretical basis for basic research,clinical application and further development and utilization of atractylodin. 展开更多
关键词 ATRACTYLODIN PHARMACOLOGICAL action purification PROCESS CONTENT DETERMINATION
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An Affordable and Easily Accessible Approach for Acrylonitrile Monomer Purification through a Simple Column Technique
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作者 Rawdah Whba Mohd Sukor Su’ait Azizan Ahmad 《Journal of Materials Science and Chemical Engineering》 2024年第4期18-28,共11页
This manuscript presents a dataset detailing a method for purifying monomers. Purification plays a crucial role in every chemical process, as it leads to an improvement in product quality through the removal of impuri... This manuscript presents a dataset detailing a method for purifying monomers. Purification plays a crucial role in every chemical process, as it leads to an improvement in product quality through the removal of impurities. The primary method for monomer purification, like acrylonitrile (AN), is the distillation technique. However, this technique is unsafe and hard to set up or handle. A straightforward, risk-free, low-cost method like the column technique resolves these issues. A simple column technique demonstrated the successful execution of purifying AN. Fourier transform infrared (FTIR) and nuclear magnetic resonance (NMR) analyses confirmed that AN was successfully purified, with purity reaching 99.8%. FTIR spectra revealed changes in the position and intensity of the stretching vibration peaks after purification. Also, the functional groups of the inhibitor monomethyl ether of hydroquinone (MeHQ) were undetected after purification. Furthermore, after purification, NMR spectra revealed the absence of aromatic protons and carbons associated with MeHQ. In conclusion, the column technique is a successful and inexpensive way to purify AN monomers. This makes it useful for a wide range of applications, especially in polymerization reactions where MeHQ needs to be removed to prevent self-polymerization during the initiation process. 展开更多
关键词 Liquid Monomers ACRYLONITRILE purification Inhibitor Simple Column
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Shock index of patients with sepsis after continuous blood purification treatment and its relationship with systemic inflammatory response syndrome and immune response 被引量:1
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作者 Wei-Jian Lei 《Journal of Hainan Medical University》 2017年第11期59-62,共4页
Objective:To study the shock index of patients with sepsis after continuous blood purification (CBP) treatment and its relationship with systemic inflammatory response syndrome and immune response.Methods:A total of 8... Objective:To study the shock index of patients with sepsis after continuous blood purification (CBP) treatment and its relationship with systemic inflammatory response syndrome and immune response.Methods:A total of 88 patients with sepsis who underwent continuous blood purification treatment in our hospital between June 2012 and May 2016 were chosen as research subjects, shock index (SI) was compared before and after the treatment, and according to the level of SI after treatment, all patients were divided into shock group (n=27) with SI>0.5 points and no shock group (n=61) with SI≤0.5 points. Serum contents of inflammatory mediators, Th1/Th2 cellular immunity indexes, immunoglobulin and complement were compared between two groups of patients after treatment.Results: The level of SI in patients with sepsis was significantly lower than that before treatment. Serum contents of inflammatory mediators PCT, CRP and HMGB1 in no shock group were lower than those in shock group, contents of Th1 cytokines IL-2 and IFN-γ were higher than those in shock group, contents of Th2 cytokines IL-10 and IL-13 were lower than those in shock group, and contents of IgG, IgM, IgA, C3 and C4 were higher than those in shock group.Conclusion: The level of SI decreases in the patients with sepsis after CBP treatment, and SI level is directly correlated with the systemic inflammatory response syndrome and immune response levels. 展开更多
关键词 SEPSIS CONTINUOUS blood purification Shock index systemIC inflammatory RESPONSE syndrome Immune RESPONSE
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Polysulfide nanoparticles-reduced graphene oxide composite aerogel for efficient solar-driven water purification 被引量:1
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作者 Fantao Meng Yuang Zhang +2 位作者 Shufen Zhang Benzhi Ju Bingtao Tang 《Green Energy & Environment》 SCIE EI CSCD 2023年第1期267-274,共8页
Along with the environmental pollution, the scarcity of clean water seriously threatens the sustainable development of human society.Recently, the rapid development of solar evaporators has injected new vitality into ... Along with the environmental pollution, the scarcity of clean water seriously threatens the sustainable development of human society.Recently, the rapid development of solar evaporators has injected new vitality into the field of water purification. However, the industry faces a considerable challenge of achieving comprehensive purification of ions, especially the efficient removal of mercury ions. In this work, we introduce an ideal mercury-removal platform based on facilely and cost-effectively synthesized polysulfide nanoparticles(PSNs). Further development of PSN-functionalized reduced graphene oxide(PSN-rGO) aerogel evaporator results in achieving a high evaporation rate of 1.55 kg m^(-2)h^(-1)with energy efficiency of 90.8% under 1 sun. With the merits of interconnected porous structure and adsorption ability, the photothermal aerogel presents overall purification of heavy metal ions from wastewater. During solar desalination, salt ions can be rejected with long-term stability. Compared with traditional water purification technologies, this highly efficient solar evaporator provides a new practical method to utilize clean energy for clean water production. 展开更多
关键词 Composite aerogel Solar vapor generation Photothermal conversion Water purification
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LARGE SCALE PURIFICATION OF PHOSPHOGLYCERATE KINASE(PGK) AND GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE(GAPDH) FROMYELLOW PEAS BY PEG/REPPAL PES AQUEOUS TWO PHASE SYSTEM AND ION EXCHANGE CHROMATOGRAPHY
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作者 Tian-wei TAN Zhong-Yao SHEN (Department of Chemical Engineering,Tsinghua University,Beijing 100084,P. R. China) 《高校化学工程学报》 EI CAS CSCD 1994年第S1期77-79,共3页
LARGESCALEPURIFICATIONOFPHOSPHOGLYCERATEKINASE(PGK)ANDGLYCERALDEHYDE3-PHOSPHATEDEHYDROGENASE(GAPDH)FROMYELLO... LARGESCALEPURIFICATIONOFPHOSPHOGLYCERATEKINASE(PGK)ANDGLYCERALDEHYDE3-PHOSPHATEDEHYDROGENASE(GAPDH)FROMYELLOWPEASBYPEG/REPPAL... 展开更多
关键词 GAPDH purification BY CHROMATOGRAPHY DEHYDROGENASE EXCHANGE FROMYELLOW AND GLYCERALDEHYDE KINASE
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Enhancement of wettability in AZ91/B_(4)C system by a mechanical purification of liquid alloy
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作者 Artur Kudyba Wojciech Polkowski +2 位作者 Grzegorz Bruzda Adelajda Polkowska Donatella Giuranno 《Journal of Magnesium and Alloys》 SCIE EI CAS CSCD 2022年第11期3133-3142,共10页
Mg-based alloys are potential candidate materials for a fabrication of lightweight boron carbide based composites through a reactive melt infiltration approach. In this paper, the effect of a mechanical purification o... Mg-based alloys are potential candidate materials for a fabrication of lightweight boron carbide based composites through a reactive melt infiltration approach. In this paper, the effect of a mechanical purification of molten AZ91 alloy’s surface on its wettability with polycrystalline B_(4)C is experimentally evaluated for the first time. For this purpose, sessile drop experiments were performed under the same operating conditions(700℃/5 min;Ar atmosphere), by using both the classical contact heating(CH) and the improved capillary purification(CP) procedure. It was found that the evolution of contact angle values was strongly influenced by the applied procedure. In particular, by using the classical CH procedure, the presence of a native oxide layer on the metal surface hinders the observations of melting process, resulting in a misleading conclusion that the system is non-wettable. Contrarily, during the wetting test performed by applying the CP procedure, the surface oxide layer was mechanically removed by squeezing the molten AZ91 alloy through a capillary. Accordingly, the oxide-free AZ91 drop with a regular and spherical shape was successfully obtained and dispensed on the B_(4)C substrate. A reliable contact angle value of θ =83° was measured at the AZ91/B_(4)C triple line at 700 ℃, which in turn proves that B_(4)C is wetted by the liquid AZ91 alloy. In contradiction to the literature, these good wetting conditions were assisted by a non-reactive wetting mechanism occurring at the AZ91/B_(4)C interface. To succeed in the fabrication of AZ91/B_(4)C composites by liquid metal infiltration, such experimental observations make it reasonable to expect a spontaneous infiltration process exclusively driven by capillarity, which in turn increases the efficiency of the process by the absence of reaction products that could be a potentially detrimental factor. 展开更多
关键词 AZ91 magnesium alloy Magnesium matrix composites Sessile drop Capillary purification procedure WETTABILITY Contact angle MMCS B_(4)C
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Self-error-rejecting multipartite entanglement purification for electron systems assisted by quantum-dot spins in optical microcavities
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作者 刘永婷 吴一鸣 杜芳芳 《Chinese Physics B》 SCIE EI CAS CSCD 2022年第5期113-121,共9页
We present a self-error-rejecting multipartite entanglement purification protocol(MEPP)for N-electron-spin entangled states,resorting to the single-side cavity-spin-coupling system.Our MEPP has a high efficiency conta... We present a self-error-rejecting multipartite entanglement purification protocol(MEPP)for N-electron-spin entangled states,resorting to the single-side cavity-spin-coupling system.Our MEPP has a high efficiency containing two steps.One is to obtain high-fidelity N-electron-spin entangled systems with error-heralded parity-check devices(PCDs)in the same parity-mode outcome of three electron-spin pairs,as well as M-electron-spin entangled subsystems(2≤M<N)in the different parity-mode outcomes of those.The other is to regain the N-electron-spin entangled systems from Melectron-spin entangled states utilizing entanglement link.Moreover,the quantum circuits of PCDs make our MEPP works faithfully,due to the practical photon-scattering deviations from the finite side leakage of the microcavity,and the limited coupling between a quantum dot and a cavity mode,converted into a failed detection in a heralded way. 展开更多
关键词 quantum communication entanglement purification electron-spin system
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Liver replacement therapy with extracorporeal blood purification techniques current knowledge and future directions 被引量:1
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作者 Panagiotis Papamichalis Katerina G Oikonomou +11 位作者 Asimina Valsamaki Maria Xanthoudaki Periklis Katsiafylloudis Evangelia Papapostolou Apostolia-Lemonia Skoura Michail Papamichalis Marios Karvouniaris Antonios Koutras Eleni Vaitsi Smaragdi Sarchosi Antonios Papadogoulas Dimitrios Papadopoulos 《World Journal of Clinical Cases》 SCIE 2023年第17期3932-3948,共17页
Clinically,it is highly challenging to promote recovery in patients with acute liver failure(ALF)and acute-on-chronic liver failure(ACLF).Despite recent advances in understanding the underlying mechanisms of ALF and A... Clinically,it is highly challenging to promote recovery in patients with acute liver failure(ALF)and acute-on-chronic liver failure(ACLF).Despite recent advances in understanding the underlying mechanisms of ALF and ACLF,standard medical therapy remains the primary therapeutic approach.Liver transplantation(LT)is considered the last option,and in several cases,it is the only intervention that can be lifesaving.Unfortunately,this intervention is limited by organ donation shortage or exclusion criteria such that not all patients in need can receive a transplant.Another option is to restore impaired liver function with artificial extracorporeal blood purification systems.The first such systems were developed at the end of the 20th century,providing solutions as bridging therapy,either for liver recovery or LT.They enhance the elimination of metabolites and substances that accumulate due to compromised liver function.In addition,they aid in clearance of molecules released during acute liver decompensation,which can initiate an excessive inflammatory response in these patients causing hepatic encephalopathy,multiple-organ failure,and other complications of liver failure.As compared to renal replacement therapies,we have been unsuccessful in using artificial extracorporeal blood purification systems to completely replace liver function despite the outstanding technological evolution of these systems.Extracting middle to high-molecular-weight and hydrophobic/protein-bound molecules remains extremely challenging.The majority of the currently available systems include a combination of methods that cleanse different ranges and types of molecules and toxins.Furthermore,conventional methods such as plasma exchange are being re-evaluated,and novel adsorption filters are increasingly being used for liver indications.These strategies are very promising for the treatment of liver failure.Nevertheless,the best method,system,or device has not been developed yet,and its probability of getting developed in the near future is also low.Furthermore,little is known about the effects of liver support systems on the overall and transplant-free survival of these patients,and further investigation using randomized controlled trials and meta-analyses is needed.This review presents the most popular extracorporeal blood purification techniques for liver replacement therapy.It focuses on general principles of their function,and on evidence regarding their effectiveness in detoxification and in supporting patients with ALF and ACLF.In addition,we have outlined the basic advantages and disadvantages of each system. 展开更多
关键词 Liver failure TRANSPLANTATION Blood purification Liver replacement therapy Artificial extracorporeal systems Transplant-free survival
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Expression and Purification of Serine/Arginine-Rich Splicing Factor 1 from Escherichia coli Expression System
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作者 张敏敏 张云龙 +1 位作者 陈婷 陆昌瑞 《Journal of Donghua University(English Edition)》 CAS 2022年第5期441-445,共5页
Serine/arginine-rich splicing factor 1(SRSF1), as a prototype member of the highly conserved serine/arginine family of RNA binding proteins, plays an important role in mRNA alternative splicing, stabilization, nuclear... Serine/arginine-rich splicing factor 1(SRSF1), as a prototype member of the highly conserved serine/arginine family of RNA binding proteins, plays an important role in mRNA alternative splicing, stabilization, nuclear export, and translation. Here, the expression system was established to purify full-length human SRSF1 from Escherichia coli(E. coli). The SRSF1 coding sequence was amplified by polymerase chain reaction(PCR) and inserted into the pET-28 a-ppSUMO vector with His-tag to construct a recombinant plasmid His-SUMO-SRSF1. Then the plasmid was transformed into BL21(DE3) competent cells for expression. After purification by affinity chromatography and cleavage of His-SUMO moiety, a highly purified SRSF1 with a molecular weight of around 28 kg/mol was obtained. The protein was analyzed by sizing chromatography and it was found that SRSF1 would form a polymer structure in the solution. According to Expasy bioinformatics analysis, SRSF1 is extremely unstable. Purification of full-length SRSF1 protein provides an opportunity to study mRNA splicing in vitro. 展开更多
关键词 protein purification serine/arginine-rich splicing factor 1(SRSF1) SUMO SUMO protease BIOINFORMATICS chromatography
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Development and Applications of a Calmodulin-Based Fusion Protein System for the Expression and Purification of WW and Zinc Finger Modules
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作者 Christopher G. Toomey David Weiss +6 位作者 Alan Chant Megan Ackerman Bethany A. Ahlers Ying-Wai Lam Christopher Ricciardi Dana Bourne Christina M. Kraemer-Chant 《Advances in Biological Chemistry》 2017年第2期89-106,共18页
Calmodulin from Homo sapiens is an α-helical calcium-binding protein that expresses to high levels in E. coli. When the N-terminus of a calmodulin variant is bound to Ca2+, it undergoes a conformational change, expos... Calmodulin from Homo sapiens is an α-helical calcium-binding protein that expresses to high levels in E. coli. When the N-terminus of a calmodulin variant is bound to Ca2+, it undergoes a conformational change, exposing hydrophobic pockets. This property can be utilized for purification purposes, as these pockets bind to phenyl sepharose resin with high affinity. Washing with EDTA chelates the Ca2+ ions from the protein, inducing a conformational change back to the more folded state and eluting the protein from the column. We describe herein the use of a protein expression and purification technique using the calmodulin variant and a short linker for proteolytic cleavage by the mutant NIa-Pro tobacco etch virus protease. We have shown this approach to be useful in obtaining purified quantities of various small proteins that could not be expressed using other methods, including high enough concentrations of a designed WW domain protein for NMR structural analysis. We have also obtained promising results on the usefulness of this procedure to express and purify zinc finger proteins without the addition of zinc ions or other cofactors. 展开更多
关键词 BIOMATERIALS PROTEIN purification EXPRESSION systems PROTEIN EXPRESSION
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An efficient purification equipment for steam turbine oil system—Larae flow oil wash down installation
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作者 Xu Futian Si Xiaojun Shandong Electric Power Bureau 《Electricity》 1991年第1期54-55,共2页
The large flow oil wash down purification equipment for steamturbine oil system is developed and produced by bothShandong Electric Power Test and Research Institute and ZouxianThermal Power Plant.With this equipment,t... The large flow oil wash down purification equipment for steamturbine oil system is developed and produced by bothShandong Electric Power Test and Research Institute and ZouxianThermal Power Plant.With this equipment,the turbine oil system 展开更多
关键词 INSTALLATION steam purification TURBINE entering
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Solubility study and selective purification of HMX explosive in organic electrolyte solution of zinc acetate/diethylene glycol
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作者 Javad Ghorbani Sajjad Damiri Hamid Reza Pouretedal 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2023年第11期15-23,共9页
In this study, an organic electrolyte solution based on zinc acetate/diethylene glycol(ZA/DEG) is introduced for the selective purification of cyclotetramethylene tetranitramine(HMX) high explosive from its identical ... In this study, an organic electrolyte solution based on zinc acetate/diethylene glycol(ZA/DEG) is introduced for the selective purification of cyclotetramethylene tetranitramine(HMX) high explosive from its identical homologue cyclotrimethylene trinitramine(RDX). The dielectric constant of various organic solutions were investigated through Electrochemical Impedance Spectroscopy(EIS) in the range of 1.0 Hz—30 MHz. and some quantum-chemical descriptors of RDX and HMX dissolutions in the ZA cosolvent were analyzed using Density Functional Theory(DFT). The results show dielectric constant and solubility of RDX is higher than that of HMX, and by increasing of ZA concentration in DEG solvent, the values of dielectric constants were enhanced. Furthermore, the presence of ZA cosolvent on the solubility of two explosives was statistically investigated by Central Composite Design(CCD) of experiment, and some solubility parameters including activity coefficient, dissolving enthalpy, and mixing enthalpies were determined. The experimental results indicate that the weight ratio of RDX to HMX solubility in the proposed organic electrolyte changes up to 30 times, which provides a selective and sequential separation method to separate two materials with similar chemical properties with a separation efficiency>98% and HMX purity> 99.8%. The X-Ray Diffraction(XRD) analysis, High-Performance Liquid Chromatography(HPLC), Laser-Induced Breakdown Spectroscopy(LIBS), and Fourier Transform Infrared Spectroscopy(FT-IR) approves the acceptable quality of the separated materials. The proposed method makes the efficient and safe purification of high-quality HMX for application in oil and gas well perforating gun charges, using a nonvolatile and inflammable organic electrolyte. 展开更多
关键词 Organic electrolyte purification SOLUBILITY HMX RDX Diethylene glycol
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