Two new pyrone derivatives phelligridins A 1 and B 2 were isolated from the fruit body of Phellinus igniarius. Their structrues were elucidated as 8, 9-dihydroxy-3-methyl-1H,6H- pyrano[4,3-c][2]benzopyran-1,6-dione a...Two new pyrone derivatives phelligridins A 1 and B 2 were isolated from the fruit body of Phellinus igniarius. Their structrues were elucidated as 8, 9-dihydroxy-3-methyl-1H,6H- pyrano[4,3-c][2]benzopyran-1,6-dione and 4-hydroxy-6-(3,4-dihydroxystyryl)-3-methoxycarbon- yl-2-pyrone , respectively, by means of spectral methods, including IR, MS, 1D and 2DNMR spectra.展开更多
A novel pyrone derivative was isolated from the ethyl acetate extract of a culture broth of a strain of the fungus Cephalosporium sp. AL031. Its structure was characterized as 7-hydroxy-9-methoxyl-10-methyl-2H, 4all, ...A novel pyrone derivative was isolated from the ethyl acetate extract of a culture broth of a strain of the fungus Cephalosporium sp. AL031. Its structure was characterized as 7-hydroxy-9-methoxyl-10-methyl-2H, 4all, 6H, 10bH-pyrano[5, 6-c][2]benzopyran-2, 6-dione by spectroscopic analysis including IR, MS, ID and 2D NMR spectra.展开更多
A facile total synthesis of 6-pentyl-α-pyrone 1 has been described.The key step is the treatment of 2-furyl-pentyl-csrbinol 3 with NBS in aqueous tetrahydrofuran(THF).The overall yield is 34%.
With maleic acid as the raw material, 6-methyl-4-hydroxy-2-pyrone, 6-methyl-4-alkoxy-2-pyrone and 6-methyl-4-hydroxy-3-acyl-2-pyrone derivatives were obtained via loop closing, O-alkylation and acylation reaction, and...With maleic acid as the raw material, 6-methyl-4-hydroxy-2-pyrone, 6-methyl-4-alkoxy-2-pyrone and 6-methyl-4-hydroxy-3-acyl-2-pyrone derivatives were obtained via loop closing, O-alkylation and acylation reaction, and antifungal activity was also tested. Structure of products was characterized by 1H NMR and MS, and preliminary biological activity tests showed that some of this series of compounds had good inhibitory activity against Rhizoctonia solani and Fusarium mo- niliforme Sheld.展开更多
Removal of copper ions from copper sulphate solutions on a rotating zinc rod in absence and in presence of 3(2H)-furanones and 4H-pyran-4-one derivatives was investigated experimentally. Variables studied were initial...Removal of copper ions from copper sulphate solutions on a rotating zinc rod in absence and in presence of 3(2H)-furanones and 4H-pyran-4-one derivatives was investigated experimentally. Variables studied were initial copper ions concentration, rotational speed of the zinc rod, temperature and concentration of organic additives. It was found that cementation reaction is first order in presence and in absence of additives. Increasing concentration of initial copper ions, rotational speed of the zinc rod and temperature were found to increase the rate of cementation. In presence of organic additives an enhancement of the rate was observed, except in presence of methoxyfuranone the rate was found to decrease by an amount ranging from 11.74% to 33.79%. Rate acceleration or inhibition is associated mainly with changes in the structure of the additives as well as its concentration. The apparent activation energy for the cementation process in presence of different additives was estimated and was found to be ranged between 11.8 kJ/mol and 25.95 kJ/mol. These values suggest that the copper removal process in presence of these additives is controlled by diffusion. A scanning electron microscopy study of copper deposits obtained in presence of tolylfuranone, phenylpyrone and methoxyfuranone correlate with their behaviour during the kinetic study. Different reaction conditions and the physical properties of solutions were studied to obtain dimensionless correlation among all these parameters. It was found that on applying cementation reaction on a sample from industrial wastewater in presence of phenylpyrone about 91.9% of Cu2+ are removed.展开更多
A new compound,3-butyryl-6-[rel-（1S,2S）-1,2-dihydroxypropyl]-4-hydroxy-2H-pyran-2-one（1）,was isolated from the solid fermented rice culture of Alternaria sp.CIB 108,along with three known ones,deoxyradicinin（2）,...A new compound,3-butyryl-6-[rel-（1S,2S）-1,2-dihydroxypropyl]-4-hydroxy-2H-pyran-2-one（1）,was isolated from the solid fermented rice culture of Alternaria sp.CIB 108,along with three known ones,deoxyradicinin（2）,3-epiradicinol（3）,and 3- epideoxyradicinol（4）.Their structures were elucidated on the basis of spectroscopic data.The single crystal X-ray diffraction was applied to further clarify the structure of 1.Furthermore,compounds 1-4 possessed no cytotoxicity against several cell lines（HeLa, HepG2,and Ros） and showed no antibacterial activity at 40μmol/L.展开更多
基金financial support from National“863”program of P.R.China(Grant No.2001AA234021).
文摘Two new pyrone derivatives phelligridins A 1 and B 2 were isolated from the fruit body of Phellinus igniarius. Their structrues were elucidated as 8, 9-dihydroxy-3-methyl-1H,6H- pyrano[4,3-c][2]benzopyran-1,6-dione and 4-hydroxy-6-(3,4-dihydroxystyryl)-3-methoxycarbon- yl-2-pyrone , respectively, by means of spectral methods, including IR, MS, 1D and 2DNMR spectra.
文摘A novel pyrone derivative was isolated from the ethyl acetate extract of a culture broth of a strain of the fungus Cephalosporium sp. AL031. Its structure was characterized as 7-hydroxy-9-methoxyl-10-methyl-2H, 4all, 6H, 10bH-pyrano[5, 6-c][2]benzopyran-2, 6-dione by spectroscopic analysis including IR, MS, ID and 2D NMR spectra.
文摘A facile total synthesis of 6-pentyl-α-pyrone 1 has been described.The key step is the treatment of 2-furyl-pentyl-csrbinol 3 with NBS in aqueous tetrahydrofuran(THF).The overall yield is 34%.
基金Supported by Research Award Fund for Outstanding Young Scientists in Shandong Province(BS2011NY015)Science and Technology Development Plan of Shandong Province(2011GNC11101)"Twelfth Five-Year"Key Technology R&D Program(2011BAE06B004-11)
文摘With maleic acid as the raw material, 6-methyl-4-hydroxy-2-pyrone, 6-methyl-4-alkoxy-2-pyrone and 6-methyl-4-hydroxy-3-acyl-2-pyrone derivatives were obtained via loop closing, O-alkylation and acylation reaction, and antifungal activity was also tested. Structure of products was characterized by 1H NMR and MS, and preliminary biological activity tests showed that some of this series of compounds had good inhibitory activity against Rhizoctonia solani and Fusarium mo- niliforme Sheld.
文摘Removal of copper ions from copper sulphate solutions on a rotating zinc rod in absence and in presence of 3(2H)-furanones and 4H-pyran-4-one derivatives was investigated experimentally. Variables studied were initial copper ions concentration, rotational speed of the zinc rod, temperature and concentration of organic additives. It was found that cementation reaction is first order in presence and in absence of additives. Increasing concentration of initial copper ions, rotational speed of the zinc rod and temperature were found to increase the rate of cementation. In presence of organic additives an enhancement of the rate was observed, except in presence of methoxyfuranone the rate was found to decrease by an amount ranging from 11.74% to 33.79%. Rate acceleration or inhibition is associated mainly with changes in the structure of the additives as well as its concentration. The apparent activation energy for the cementation process in presence of different additives was estimated and was found to be ranged between 11.8 kJ/mol and 25.95 kJ/mol. These values suggest that the copper removal process in presence of these additives is controlled by diffusion. A scanning electron microscopy study of copper deposits obtained in presence of tolylfuranone, phenylpyrone and methoxyfuranone correlate with their behaviour during the kinetic study. Different reaction conditions and the physical properties of solutions were studied to obtain dimensionless correlation among all these parameters. It was found that on applying cementation reaction on a sample from industrial wastewater in presence of phenylpyrone about 91.9% of Cu2+ are removed.
基金supported financially by the NSFC(No.20902089 to G.Y.Li)the Knowledge Innovation Program of the Chinese Academy of Sciences(No.KSCX2-EW-G-13-04)
文摘A new compound,3-butyryl-6-[rel-（1S,2S）-1,2-dihydroxypropyl]-4-hydroxy-2H-pyran-2-one（1）,was isolated from the solid fermented rice culture of Alternaria sp.CIB 108,along with three known ones,deoxyradicinin（2）,3-epiradicinol（3）,and 3- epideoxyradicinol（4）.Their structures were elucidated on the basis of spectroscopic data.The single crystal X-ray diffraction was applied to further clarify the structure of 1.Furthermore,compounds 1-4 possessed no cytotoxicity against several cell lines（HeLa, HepG2,and Ros） and showed no antibacterial activity at 40μmol/L.
