Kawasaki disease(KD) is an acute, febrile vasculitis that predominantly develops in children ≤ 5 years of age and can lead to multiple organ injuries including the kidneys. Of these injuries, pyuria is a common featu...Kawasaki disease(KD) is an acute, febrile vasculitis that predominantly develops in children ≤ 5 years of age and can lead to multiple organ injuries including the kidneys. Of these injuries, pyuria is a common feature of patients with KD, occurring in 30%-80% of patients. Sterile pyuria is most common in KD patients ≤ 1 year of age. KD patients with sterile pyuria exhibit more severe inflammatory reactions and may have subclinical renal injuries. Sterile pyuria in KD is associated with mononuclear cells(not neutrophils) in the urine. Although sterile pyuria in KD was at one time thought to be due to urethritis caused by a non-specific vasculitis of the urethra, recent studies suggest that sterile pyuria in KD originates from the urethra, the kidney as a resultof mild and sub-clinical renal injuries, and/or the bladder due to cystitis. Pyuria is not always sterile in KD, but can result from a urinary tract infection(UTI). As causative pathogens, Escherichia coli and Klebsiella oxytoca have been reported. The clinical phenotypes do not differ between those with or without UTI. Because some KD patients with UTIs have urinary tract abnormalities such as vesicoureteral reflux, a complete UTI workup including renal ultrasound, voiding cystourethrogram and/or dimercaptosuccinic acid renal scan recommended in KD patients with UTIs.展开更多
Follicular cystitis is a non-specific inflammatory condition of the bladder where the aetiology is unknown.The extent of the disease can be mild or proliferative and bulky.Antibiotics,steroids,therapies used for inter...Follicular cystitis is a non-specific inflammatory condition of the bladder where the aetiology is unknown.The extent of the disease can be mild or proliferative and bulky.Antibiotics,steroids,therapies used for interstitial cystitis,palliative cystectomy and radiotherapy have been reported as successful treatment options.We report a case of follicular cystitis that responded to a course of oral diethyl carbamazine.展开更多
Introduction: Testing for the presence of micro-organisms in the urinary tract, in order to diagnose asymptomatic bacteriuria or symptomatic urinary tract infections (UTI), is very common at all levels of health care....Introduction: Testing for the presence of micro-organisms in the urinary tract, in order to diagnose asymptomatic bacteriuria or symptomatic urinary tract infections (UTI), is very common at all levels of health care. This study was conducted to assess the diagnostic values for bacteriuria and pyuria and evaluate their roles in therapeutic decision making. Methods: A total of 1770 urine samples were obtained by simple randomized method from the central Laboratory of the Ali-ebne-Abitaleb Hospital (Zahedan, Iran). Urine culture was done to compare urine microscopy profiles. Sensitivity, specificity, positive and negative predictive values of the findings of urine analysis was described. Results: 1055 (59.6%) of the cases were females. 13% (230/1770) of patients had positive urine cultures. The most prevalent cultured micro-organism was E. coli (63%). Sensitivity, specificity, positive and negative predictive values of microscopic pyuria were 85%, 88%, 51%, 97%, respectively. As the same for bacteriuria, these calculations were 97%, 98%, 90%, 99% and for the category with both bacteriuria and pyuria were 82%, 99%, 95%, 97%, respectively. Conclusion: According to the results, it is concluded that the urine microscopy features seems to be useful to exclude the presence of infection if the results of both bacteriuria and pyuria are negative, but positive test results have to be confirmed.展开更多
文摘Kawasaki disease(KD) is an acute, febrile vasculitis that predominantly develops in children ≤ 5 years of age and can lead to multiple organ injuries including the kidneys. Of these injuries, pyuria is a common feature of patients with KD, occurring in 30%-80% of patients. Sterile pyuria is most common in KD patients ≤ 1 year of age. KD patients with sterile pyuria exhibit more severe inflammatory reactions and may have subclinical renal injuries. Sterile pyuria in KD is associated with mononuclear cells(not neutrophils) in the urine. Although sterile pyuria in KD was at one time thought to be due to urethritis caused by a non-specific vasculitis of the urethra, recent studies suggest that sterile pyuria in KD originates from the urethra, the kidney as a resultof mild and sub-clinical renal injuries, and/or the bladder due to cystitis. Pyuria is not always sterile in KD, but can result from a urinary tract infection(UTI). As causative pathogens, Escherichia coli and Klebsiella oxytoca have been reported. The clinical phenotypes do not differ between those with or without UTI. Because some KD patients with UTIs have urinary tract abnormalities such as vesicoureteral reflux, a complete UTI workup including renal ultrasound, voiding cystourethrogram and/or dimercaptosuccinic acid renal scan recommended in KD patients with UTIs.
文摘Follicular cystitis is a non-specific inflammatory condition of the bladder where the aetiology is unknown.The extent of the disease can be mild or proliferative and bulky.Antibiotics,steroids,therapies used for interstitial cystitis,palliative cystectomy and radiotherapy have been reported as successful treatment options.We report a case of follicular cystitis that responded to a course of oral diethyl carbamazine.
文摘Introduction: Testing for the presence of micro-organisms in the urinary tract, in order to diagnose asymptomatic bacteriuria or symptomatic urinary tract infections (UTI), is very common at all levels of health care. This study was conducted to assess the diagnostic values for bacteriuria and pyuria and evaluate their roles in therapeutic decision making. Methods: A total of 1770 urine samples were obtained by simple randomized method from the central Laboratory of the Ali-ebne-Abitaleb Hospital (Zahedan, Iran). Urine culture was done to compare urine microscopy profiles. Sensitivity, specificity, positive and negative predictive values of the findings of urine analysis was described. Results: 1055 (59.6%) of the cases were females. 13% (230/1770) of patients had positive urine cultures. The most prevalent cultured micro-organism was E. coli (63%). Sensitivity, specificity, positive and negative predictive values of microscopic pyuria were 85%, 88%, 51%, 97%, respectively. As the same for bacteriuria, these calculations were 97%, 98%, 90%, 99% and for the category with both bacteriuria and pyuria were 82%, 99%, 95%, 97%, respectively. Conclusion: According to the results, it is concluded that the urine microscopy features seems to be useful to exclude the presence of infection if the results of both bacteriuria and pyuria are negative, but positive test results have to be confirmed.
