Studies in vitro show that intravascular ultrasound (IVUS) underestimates vessel and lumen dimensions. In order to validate IVUS measurement in vivo, we conducted a comparative study during catheterization in fifty pa...Studies in vitro show that intravascular ultrasound (IVUS) underestimates vessel and lumen dimensions. In order to validate IVUS measurement in vivo, we conducted a comparative study during catheterization in fifty patients. The patients underwent IVUS examinations for the purpose of diagnosis or treatment of coronary artery disease. The IVUS system was a 3.5 F, 20 MHz IVUS catheter (Sonicath catheter of Boston Scientific Co.) and a Hewlett Packard console. After examination of the coronary artery, the IVUS probe was withdrawn back into the guiding catheter to measure the average lumen diameter of the guiding catheter (8 F, Cordis). This measurement in vivo (VI) was compared with the true lumen diameter provided by the manufac Department of Cardiology, University of Essen, Essen, Germany (Liu FQ, Ge JB, Baumgart D, Haude M, Caspari G, Grge G, Eick B and Erbel R) turer (MA) and determined by on line quantitative angiography (HICOR, Siemens) (HI). In addition, the IVUS measurement in vitro (VT) was also taken with the same guiding catheter in waterbath at 37℃. The results showed that IVUS underestimated the true lumen diameter by 2.2%±2.6% in vivo, by 3.1%±1.8% in vitro, while HICOR owerestimated the true lumen diameter by 23.0%±6.8%. There was no difference between the IVUS measurements in vivo and in vitro. In summary, IVUS was very accurate for the measurement of a 8 F guiding catheter in vivo with only a minor underestimation, and IVUS measurement was far more reliable than the on line quantitative angiography.展开更多
文摘Studies in vitro show that intravascular ultrasound (IVUS) underestimates vessel and lumen dimensions. In order to validate IVUS measurement in vivo, we conducted a comparative study during catheterization in fifty patients. The patients underwent IVUS examinations for the purpose of diagnosis or treatment of coronary artery disease. The IVUS system was a 3.5 F, 20 MHz IVUS catheter (Sonicath catheter of Boston Scientific Co.) and a Hewlett Packard console. After examination of the coronary artery, the IVUS probe was withdrawn back into the guiding catheter to measure the average lumen diameter of the guiding catheter (8 F, Cordis). This measurement in vivo (VI) was compared with the true lumen diameter provided by the manufac Department of Cardiology, University of Essen, Essen, Germany (Liu FQ, Ge JB, Baumgart D, Haude M, Caspari G, Grge G, Eick B and Erbel R) turer (MA) and determined by on line quantitative angiography (HICOR, Siemens) (HI). In addition, the IVUS measurement in vitro (VT) was also taken with the same guiding catheter in waterbath at 37℃. The results showed that IVUS underestimated the true lumen diameter by 2.2%±2.6% in vivo, by 3.1%±1.8% in vitro, while HICOR owerestimated the true lumen diameter by 23.0%±6.8%. There was no difference between the IVUS measurements in vivo and in vitro. In summary, IVUS was very accurate for the measurement of a 8 F guiding catheter in vivo with only a minor underestimation, and IVUS measurement was far more reliable than the on line quantitative angiography.
