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Wavelength-interval switchable Brillouin–Raman random fiber laser through Brillouin pump manipulation
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作者 李阳 徐恩明 +2 位作者 陈睿佳 Yu-Gang Shee 张祖兴 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第7期374-379,共6页
A wavelength-interval switchable Brillouin–Raman random fiber laser(BRRFL) based on Brillouin pump(BP) manipulation is proposed in this paper. The proposed wavelength-interval switchable BRRFL has a full-open cavity ... A wavelength-interval switchable Brillouin–Raman random fiber laser(BRRFL) based on Brillouin pump(BP) manipulation is proposed in this paper. The proposed wavelength-interval switchable BRRFL has a full-open cavity configuration, featuring multiwavelength output with wavelength interval of double Brillouin frequency shifts. Through simultaneously injecting the BP light and its first-order stimulated Brillouin-scattered light into the cavity, the laser output exhibits a wavelength interval of single Brillouin frequency shift. The wavelength-interval switching effect can be manipulated by controlling the power of the first-order stimulated Brillouin scattering light. The experimental results show the multiwavelength output can be switched between double Brillouin frequency shift multiwavelength emission with a broad bandwidth of approximately 60 nm and single Brillouin frequency shift multiwavelength emission of 44 nm. The flexible optically controlled random fiber laser with switchable wavelength interval makes it useful for a wide range of applications and holds significant potential in the field of wavelength-division multiplexing optical communication. 展开更多
关键词 wavelength-interval switchable fiber laser Brillouin fiber laser stimulated Brillouin-scattered random fiber laser
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On the generation of high-quality Nyquist pulses in mode-locked fiber lasers
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作者 任俞宣 葛锦蔓 +2 位作者 李小军 彭俊松 曾和平 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第3期424-427,共4页
Nyquist pulses have wide applications in many areas,from electronics to optics.Mode-locked lasers are ideal platforms to generate such pulses.However,how to generate high-quality Nyquist pulses in mode-locked lasers r... Nyquist pulses have wide applications in many areas,from electronics to optics.Mode-locked lasers are ideal platforms to generate such pulses.However,how to generate high-quality Nyquist pulses in mode-locked lasers remains elusive.We address this problem by managing different physical effects in mode-locked fiber lasers through extensive numerical simulations.We find that net dispersion,linear loss,gain and filter shaping can affect the quality of Nyquist pulses significantly.We also demonstrate that Nyquist pulses experience similariton shaping due to the nonlinear attractor effect in the gain medium.Our work may contribute to the design of Nyquist pulse sources and enrich the understanding of pulse shaping dynamics in mode-locked lasers. 展开更多
关键词 mode locking laser SOLITON fiber PULSE
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Internal phase control of fiber laser array based on photodetector array
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作者 靳凯凯 龙金虎 +5 位作者 常洪祥 粟荣涛 张嘉怡 陈思雨 马阎星 周朴 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第7期320-326,共7页
Coherent beam combining(CBC) of fiber laser array is a promising technique to realize high output power while maintaining near diffraction-limited beam quality. To implement CBC, an appropriate phase control feedback ... Coherent beam combining(CBC) of fiber laser array is a promising technique to realize high output power while maintaining near diffraction-limited beam quality. To implement CBC, an appropriate phase control feedback structure should be established to realize phase-locking. In this paper, an innovative internal active phase control CBC fiber laser array based on photodetector array is proposed. The dynamic phase noises of the laser amplifiers are compensated before being emitted into free space. And the static phase difference compensation of emitting laser array is realized by interference measurement based on photodetector array. The principle of the technique is illustrated and corresponding simulations are carried out, and a CBC system with four laser channels is built to verify the technique. When the phase controllers are turned on, the phase deviation of the laser array is less than λ/20, and ~ 95% fringe contrast of the irradiation distribution is obtained. The technique proposed in this paper could provide a reference for the system design of a massive high-power CBC system. 展开更多
关键词 fiber laser laser array coherent beam combining internal phase control
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Numerical design of an efficient Ho^(3+)-doped InF3 fiber laser at~3.2μm
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作者 Shi-Yuan Zhou Hong-Yu Luo +1 位作者 Ya-Zhou Wang Yong Liu 《Journal of Electronic Science and Technology》 EI CAS CSCD 2024年第3期35-46,共12页
In this work,we theoretically unlock the potential of Ho^(3+)-doped InF3 fiber for efficient~3.2μm laser generation(from the 5F4,5S2→5F5 transition),by employing a novel dual-wavelength pumping scheme at 1150 nm and... In this work,we theoretically unlock the potential of Ho^(3+)-doped InF3 fiber for efficient~3.2μm laser generation(from the 5F4,5S2→5F5 transition),by employing a novel dual-wavelength pumping scheme at 1150 nm and 980 nm,for the first time.Under clad-coupled 1150 nm pumping of 5 W,~3.2μm power of 3.6 W has been predicted with the optical-to-optical efficiency of 14.4%.Further efficient power scaling,however,is blocked by the output saturation with 980 nm pumping.To alleviate this behavior,the cascaded 5I5→5I6 transition,targeting~3.9μm,has been activated simultaneously,therefore accelerating the population circulation between the laser upper level 5F4,5S2 and long-lived 5I6 level under 980 nm pumping.As a result,enhanced~3.2μm power of 4.68 W has been obtained with optical-to-optical efficiency of 15.6%.Meanwhile the~3.9μm laser,yielding power of 2.76 W with optical-to-optical efficiency of 9.2%,is theoretically achievable as well with a moderate heat load,of which the performance is even better than the prior experimentally and theoretically reported Ho^(3+)-doped InF3 fiber lasers emitting at~3.9μm alone.This work demonstrates a versatile platform for laser generation at~3.2μm and~3.9μm,thus providing the new opportunities for many potential applications,e.g.,polymer processing,infrared countermeasures,and free-space communications. 展开更多
关键词 Cascaded fiber laser HOLMIUM MID-INFRARED
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Broadband bidirectional Brillouin–Raman random fiber laser with ultra-narrow linewidth
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作者 杨茜 李阳 +3 位作者 邹辉 梅杰 徐恩明 张祖兴 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第2期371-376,共6页
We present a Brillouin–Raman random fiber laser(BRRFL)with full-open linear cavity structure to generate broadband Brillouin frequency comb(BFC)with double Brillouin-frequency-shift spacing.The incorporation of a reg... We present a Brillouin–Raman random fiber laser(BRRFL)with full-open linear cavity structure to generate broadband Brillouin frequency comb(BFC)with double Brillouin-frequency-shift spacing.The incorporation of a regeneration portion consisting of an erbium-doped fiber and a single-mode fiber enables the generation of broadband BFC.The dynamics of broadband BFC generation changing with the pump power(EDF and Raman)and Brillouin pump(BP)wavelength are investigated in detail,respectively.Under suitable conditions,the bidirectional BRRFL proposed can produce a flatamplitude BFC with 40.7-nm bandwidth ranging from 1531 nm to 1571.7 nm,and built-in 242-order Brillouin Stokes lines(BSLs)with double Brillouin-frequency-shift spacing.Moreover,the linewidth of single BSL is experimentally measured to be about 2.5 kHz.The broadband bidirectional narrow-linewidth BRRFL has great potential applications in optical communication,optical sensing,spectral measurement,and so on. 展开更多
关键词 random laser fiber laser stimulated Brillouin scattering(SBS) stimulated Raman scattering(SRS)
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Widely-wavelength-tunable brillouin fiber laser with improved optical signal-to-noise ratio based on parity-time symmetric and saturable absorption effect
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作者 LIU Yi JIANG Kai +5 位作者 FANG Xin-yue YOU Ya-jun HE Wen-jun HOU Jia-xin HAN Xue-feng CHOU Xiu-jian 《中国光学(中英文)》 EI CAS CSCD 北大核心 2024年第5期1244-1253,共10页
A widely-wavelength-tunable Brillouin fiber laser(BFL)with improved optical signal-to-noise ratio(OSNR)based on parity-time(PT)symmetric and saturable absorption(SA)effect is present.This novel BFL realizes PT symmetr... A widely-wavelength-tunable Brillouin fiber laser(BFL)with improved optical signal-to-noise ratio(OSNR)based on parity-time(PT)symmetric and saturable absorption(SA)effect is present.This novel BFL realizes PT symmetry and SA effect through polarization-maintaining erbium-doped fiber(PM-EDF)Sagnac loop,which is composed of a PM-EDF,a coupler and two polarization controllers(PCs).By using the inherent birefringence characteristic of PM-EDF,two feedback loops in orthogonal polarization state are formed when the Strokes signal in injected.One of these loops provides gain in the clockwise direction with in the Sagnac loop,while the other loop generates loss in the counterclockwise direction.By adjusting the PCs to control the polarization state of the PM-EDF,a single-longitudinal-mode(SLM)BFL can be achieved,as the PT symmetry is broken when the SA participating stimulated Brillouin scattering(SBS)gain and loss are well-matched and the gain surpasses the coupling coefficient.Compared to previous BFLs,the proposed BFL has a more streamlined structure and a wider wavelength tunable range,at the same time,it is not being limited by the bandwidth of the erbium-doped fiber amplifier while still maintaining narrow linewidth SLM output.Additionally,thanks to SA effect of the PM-EDF,the PT symmetric SBS gain contract is enhanced,resulting in a higher optical signal-to-noise(OSNR).The experimental results show that the laser has a wide tunable range of 1526.088 nm to 1565.498 nm,an improved OSNR of 77 dB,and a fine linewidth as small as 140.5 Hz. 展开更多
关键词 Brillouin fiber laser widely-wavelength-tunable parity-time symmetric high OSNR narrow linewidth
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Corrigendum to:“Spectrum-tailored random fiber laser towards ICF laser facility”[Matter and Radiation at Extremes 8,025902(2023)] 被引量:1
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作者 Mengqiu Fan Shengtao Lin +14 位作者 Ke Yao Yifei Qi Jiaojiao Zhang Junwen Zheng Pan Wang Longqun Ni Xingyu Bao Dandan Zhou Bo Zhang Kaibo Xiao Handing Xia Rui Zhang Ping Li Wanguo Zheng Zinan Wang 《Matter and Radiation at Extremes》 SCIE EI CAS CSCD 2023年第2期79-79,共1页
The third paragraph in Sec.IV REGENERATIVE AMPLIFICATION erroneously states“In other words,the distribution of spectral components is time-dependent,and the spectral distortion in the amplification process will not c... The third paragraph in Sec.IV REGENERATIVE AMPLIFICATION erroneously states“In other words,the distribution of spectral components is time-dependent,and the spectral distortion in the amplification process will not change the time-domain shape.” 展开更多
关键词 fiber laser EXTREME
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Comprehensive analysis of pure-quartic soliton dynamics in a passively mode-locked fiber laser 被引量:1
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作者 刘列 韩颖 +3 位作者 霍佳雨 文红琳 吴戈 高博 《Chinese Physics B》 SCIE EI CAS CSCD 2023年第11期477-483,共7页
The understanding of soliton dynamics promotes the development of ultrafast laser technology. High-energy purequartic solitons(PQSs) have gradually become a hotspot in recent years. Herein, we numerically study the in... The understanding of soliton dynamics promotes the development of ultrafast laser technology. High-energy purequartic solitons(PQSs) have gradually become a hotspot in recent years. Herein, we numerically study the influence of the gain bandwidth, saturation power, small-signal gain, and output coupler on PQS dynamics in passively mode-locked fiber lasers. The results show that the above four parameters can affect PQS dynamics. Pulsating PQSs occur as we alter the other three parameters when the gain bandwidth is 50 nm. Meanwhile, PQSs evolve from pulsating to erupting and then to splitting as the other three parameters are altered when the gain bandwidth is 10 nm, which can be attributed to the existence of the spectral filtering effect and intra-cavity fourth-order dispersion. These findings provide new insights into PQS dynamics in passively mode-locked fiber lasers. 展开更多
关键词 pure-quartic soliton pulsating soliton erupting soliton passively mode-locked fiber lasers
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Research on Infrared Emissivity and Laser Reflectivity of Sn_(1−x)Er_(x)O_(2)Micro/Nanofibers Based on First-Principles 被引量:1
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作者 Yuanjia Xia Fang Zhao +2 位作者 Zhizun Li Zhaogang Cheng Jianwei Hu 《Journal of Renewable Materials》 SCIE EI 2023年第2期921-936,共16页
Sn_(1−x)Er_(x)O_(2)(x=0%,8%,16%,24%)micro/nanofibers were prepared by electrospinning combined with heat treatment using erbium nitrate,stannous chloride and polyvinylpyrrolidone(PVP)as raw materials.The target produc... Sn_(1−x)Er_(x)O_(2)(x=0%,8%,16%,24%)micro/nanofibers were prepared by electrospinning combined with heat treatment using erbium nitrate,stannous chloride and polyvinylpyrrolidone(PVP)as raw materials.The target products were characterized by thermogravimetric analyzer,X-ray diffrotometer,fourier transform infrared spectrometer,scanning electron microscope,spectrophotometer and infrared emissivity tester,and the effects of Er^(3+)doping on its infrared and laser emissivity were studied.At the same time,the Sn_(1−x)Er_(x)O_(2)(x=0%,16%)doping models were constructed based on the first principles of density functional theory,and the related optoelectronic properties such as their energy band structure,density of states,reflectivity and dielectric constant were analyzed,and further explained the mechanism of Er^(3+)doping on SnO_(2)infrared emissivity and laser absorption from the point of electronic structure.The results showed that after calcination at 600℃,single rutile type SnO_(2)was formed,and the crystal structure was not changed by doping Er^(3+).The calcined products showed good fiber morphology,and the average fiber diameter was 402 nm.The infrared emissivity and resistivity of the samples both decreased first and then increased with the increase of Er^(3+)doping amount.When x=16%,the infrared emis-sivity of the sample was at least 0.71;and Er^(3+)doping can effectively reduce the reflectivity of SnO_(2)at 1.06μm and 1.55μm,when x=16%,its reflectivity at 1.06μm and 1.55μm are 50.5%and 40%,respectively,when x=24%,the reflectivity at 1.06μm and 1.55μm wavelengths are 47.3%and 42.1%,respectively.At the same time,the change of carrier concentration and electron transition before and after Er^(3+)doping were described by first-principle calculation,and the regulation mechanism of infrared emissivity and laser reflectivity was explained.This study provides a certain experimental and theoretical basis for the development of a single-type,light-weight and easily prepared infrared and laser compatible-stealth material. 展开更多
关键词 Micro/nano fibers Er^(3+)doping SnO_(2) laser and infrared compatible stealth material
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Single-frequency linearly polarized Q-switched fiber laser based on Nb_(2)GeTe_(4)saturable absorber
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作者 陈思雨 邓海芹 +8 位作者 张万儒 戴永平 王涛 俞强 李灿 姜曼 粟荣涛 吴坚 周朴 《Chinese Physics B》 SCIE EI CAS CSCD 2023年第7期382-386,共5页
We report a single-frequency linearly polarized Q-switched fiber laser based on an Nb_(2)GeTe_(4)saturable absorber(SA).The Nb_(2)GeTe_(4)SA triggers passive Q-switching of the laser,and an un-pumped Yb-doped fiber to... We report a single-frequency linearly polarized Q-switched fiber laser based on an Nb_(2)GeTe_(4)saturable absorber(SA).The Nb_(2)GeTe_(4)SA triggers passive Q-switching of the laser,and an un-pumped Yb-doped fiber together with a 0.08-nmbandwidth polarization-maintaining fiber Bragg grating(FBG)acts as an ultra-narrow bandwidth filter to realize singlelongitudinal-mode(SLM)oscillation.The devices used in the laser are all kept polarized,so as to ensure linearly polarized laser output.Stable SLM linearly polarized Q-switching operation at 1064.6 nm is successfully achieved,producing a laser with a shortest pulse width of 1.36μs,a linewidth of 28.4 MHz,a repetition rate of 28.3 kHz-95.9 kHz,and a polarization extinction ratio of about 30 dB.It is believed that the single-frequency linearly polarized pulsed fiber laser studied in this paper has great application value in gravitational wave detection,beam combining,nonlinear frequency conversion,and other fields. 展开更多
关键词 fiber laser saturable absorber SINGLE-LONGITUDINAL-MODE pulsed laser
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A kind of multiwavelength erbium-doped fiber laser based on Lyot filter
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作者 周哲海 吴婧仪 +2 位作者 闵昆龙 赵爽 李慧宇 《Chinese Physics B》 SCIE EI CAS CSCD 2023年第3期252-257,共6页
A multiwavelength tunable ring-cavity erbium-doped fiber laser(EDFL)based on a Lyot filter was presented.For the proposed Lyot filter,a comb filter consisting of an EDF-polarization-maintaining fiber(EDF-PMF),a polari... A multiwavelength tunable ring-cavity erbium-doped fiber laser(EDFL)based on a Lyot filter was presented.For the proposed Lyot filter,a comb filter consisting of an EDF-polarization-maintaining fiber(EDF-PMF),a polarization controller(PC),and a circulator with four ports was used to suppress the mode competition.The light transmission direction was guaranteed by the circulator.For the proposed fiber laser,tunable single,dual,triple,quadruple,quintuple,sextuple,and septuple wavelengths were realized.A single-wavelength laser output with an optical signal-to-noise ratio(SNR)of up to30.56 dB was realized,and a tuning range of 1590.54 nm to 1599.54 nm was achieved by tuning the PC.The stability of the single,dual,triple,and quadruple-wavelength center power fluctuations was less than 0.05 dB,0.98 dB,5.07 dB,and7.71 dB respectively.When the laser was operated in the multiwavelength condition,the SNR was more than 20.97 dB.The proposed erbium-doped fiber laser is suitable for fiber-sensing system applications. 展开更多
关键词 multiwavelength erbium-doped fiber laser Lyot filter polarization-maintaining fiber CIRCULATOR
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Thulium fiber laser lithotripsy:Is it living up to the hype?
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作者 John Denstedt Fernanda C.Gabrigna Berto 《Asian Journal of Urology》 CSCD 2023年第3期289-297,共9页
Objective:The holmium:yttrium-aluminium-garnet laser(Ho:YAG)has been the gold standard for laser lithotripsy over the last three decades.After demonstrating good in vitro efficacy,the thulium fiber laser(TFL)has been ... Objective:The holmium:yttrium-aluminium-garnet laser(Ho:YAG)has been the gold standard for laser lithotripsy over the last three decades.After demonstrating good in vitro efficacy,the thulium fiber laser(TFL)has been recently released in the market and the initial clinical results are encouraging.This article aims to review the main technology differences between the Ho:YAG laser and the TFL,discuss the initial clinical results with the TFL as well as the optimal settings for TFL lithotripsy.Methods:We reviewed the literature focusing on the technological aspects of the Ho:YAG laser and TFL as well as the results of in vitro and in vivo studies comparing both technologies.Results:In vitro studies show a technical superiority of TFL compared to the Ho:YAG laser and encouraging results have been demonstrated in clinical practice.However,as TFL is a new technology,limited studies are currently available,and the optimal settings for lithotripsy are not yet established.Conclusion:TFL has the potential to be an alternative to the Ho:YAG laser,but more reports are still needed to determine the optimal laser for lithotripsy of urinary tract stones when considering all parameters including effectiveness,safety,and costs. 展开更多
关键词 UROLITHIASIS Thulium fiber laser Holmium:yttriumaluminium-garnet laser laser lithotripsy
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Real-time observation of soliton pulsation in net normal-dispersion dissipative soliton fiber laser
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作者 汪徐德 耿旭 +4 位作者 潘婕妤 孙梦秋 陆梦想 李凯芯 李素文 《Chinese Physics B》 SCIE EI CAS CSCD 2023年第2期316-322,共7页
We present experimental observations of soliton pulsations in the net normal-dispersion fiber laser by using the dispersive Fourier transform(DFT) technique. According to the pulsating characteristics, the soliton pul... We present experimental observations of soliton pulsations in the net normal-dispersion fiber laser by using the dispersive Fourier transform(DFT) technique. According to the pulsating characteristics, the soliton pulsations are classified as visible and invisible soliton pulsations. The visible soliton pulsation is converted from single-into dual-soliton pulsation with the common characteristics of energy oscillation and bandwidth breathing. The invisible soliton pulsation undergoes periodic variation in the spectral profile and peak power but remains invariable in pulse energy. The reason for invisible soliton pulsation behavior is periodic oscillation of the pulse inside the soliton molecule. These results could be helpful in deepening our understanding of the soliton pulsation phenomena. 展开更多
关键词 fiber laser soliton pulsation soliton molecule dispersive Fourier transformation
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Antimonene-based saturable absorber for a soliton mode-locked and Q-switched fiber laser in the 2 μm wavelength region
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作者 H Ahmad B Nizamani +2 位作者 M Z Samion N Yusoff M F Ismail 《Chinese Physics B》 SCIE EI CAS CSCD 2023年第6期259-269,共11页
We demonstrate antimonene as a saturable absorber(SA) to generate an ultrafast mode-locked and Q-switched laser in the 2 μm wavelength region. The two antimonene-based SAs were prepared and inserted separately in a t... We demonstrate antimonene as a saturable absorber(SA) to generate an ultrafast mode-locked and Q-switched laser in the 2 μm wavelength region. The two antimonene-based SAs were prepared and inserted separately in a thulium–holmiumdoped fiber laser to produce the pulsed laser. Antimonene was coated onto a tapered fiber to generate soliton mode-locked pulses and used in thin-film form for the generation of Q-switched pulses. The mode-locking was stable within a pump power of 267 m W–511 m W, and the laser operated at a central wavelength of 1897.4 nm. The mode-locked laser had a pulse width of 1.3 ps and a repetition rate of 12.6 MHz, with a signal-to-noise ratio of 64 d B. Q-switched laser operation was stable at a wavelength of 1890.1 nm within a pump power of 312 m W–381 m W. With the increase in pump power from 312 m W to 381 m W, the repetition rate increased to a maximum of 56.63 k Hz and the pulse width decreased to a minimum value of 2.85 μs. Wide-range tunability of the Q-switched laser was also realized within the wavelength range of1882 nm–1936 nm. 展开更多
关键词 MODE-LOCKING Q-switched fiber laser optical saturable absorber
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Critical dispersion of chirped fiber Bragg grating for eliminating time delay signature of distributed feedback laser chaos
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作者 王大铭 雷一航 +1 位作者 史鹏飞 李壮爱 《Chinese Physics B》 SCIE EI CAS CSCD 2023年第9期237-241,共5页
Optical chaos has attracted widespread attention owing to its complex dynamic behaviors.However,the time delay signature(TDS)caused by the external cavity mode reduces the complexity of optical chaos.We propose and nu... Optical chaos has attracted widespread attention owing to its complex dynamic behaviors.However,the time delay signature(TDS)caused by the external cavity mode reduces the complexity of optical chaos.We propose and numerically demonstrate the critical dispersion of chirped fiber Bragg grating(CFBG)for eliminating the TDS of laser chaos in this work.The critical dispersion,as a function of relaxation frequency and bandwidth of the optical spectrum,is found through extensive dynamics simulations.It is shown that the TDS can be eliminated when the dispersion of CFBG is above this critical dispersion.In addition,the influence of dispersive feedback light and output light from a laser is investigated.These results provide important quantitative guidance for designing chaotic semiconductor lasers without TDS. 展开更多
关键词 CHAOS semiconductor laser time delay signature chirped fiber Bragg grating(CFBG)
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Dissipative soliton resonance within different dispersion regimes in a single mode-locked laser
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作者 赵哲韬 舒沁珂 +6 位作者 解梓怡 任俞宣 张颖 袁博 赵春勃 彭俊松 曾和平 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第7期368-372,共5页
Dissipative soliton resonance(DSR) was previously studied in separated mode-locked fiber lasers within different dispersion regimes including anomalous, near-zero and normal dispersion. Here we propose a method to stu... Dissipative soliton resonance(DSR) was previously studied in separated mode-locked fiber lasers within different dispersion regimes including anomalous, near-zero and normal dispersion. Here we propose a method to study DSR in a single mode-locked laser in these different dispersion regimes. This is achieved by virtue of a waveshaper which can control the laser dispersion readily using software, avoiding the usual tedious cutback method. We find that dispersion has a negligible effect on DSR since the pulse duration keeps constant while dispersion is varied. Moreover, we examine the dynamics of DSR on the parameters of the SA including modulation depth and saturation power, and find that the pulse duration can be changed in a large range when the saturation power is decreased. Our numerical simulations could be important to guide relative experimental studies. 展开更多
关键词 mode locking laser fiber PULSE
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Anti-vascular endothelial growth factor drugs combined with laser photocoagulation maintain retinal ganglion cell integrity in patients with diabetic macular edema: study protocol for a prospective, non-randomized, controlled clinical trial
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作者 Xiangjun Li Chunyan Li +5 位作者 Hai Huang Dan Bai Jingyi Wang Anqi Chen Yu Gong Ying Leng 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第4期923-928,共6页
The integrity of retinal ganglion cells is tightly associated with diabetic macular degeneration that leads to damage and death of retinal ganglion cells,affecting vision.The major clinical treatments for diabetic mac... The integrity of retinal ganglion cells is tightly associated with diabetic macular degeneration that leads to damage and death of retinal ganglion cells,affecting vision.The major clinical treatments for diabetic macular edema are anti-vascular endothelial growth factor drugs and laser photocoagulation.However,although the macular thickness can be normalized with each of these two therapies used alone,the vision does not improve in many patients.This might result from the incomplete recovery of retinal ganglion cell injury.Therefore,a prospective,non-randomized,controlled clinical trial was designed to investigate the effect of anti-vascular endothelial growth factor drugs combined with laser photocoagulation on the integrity of retinal ganglion cells in patients with diabetic macular edema and its relationship with vision recovery.In this trial,150 patients with diabetic macular edema will be equally divided into three groups according to therapeutic methods,followed by treatment with anti-vascular endothelial growth factor drugs,laser photocoagulation therapy,and their combination.All patients will be followed up for 12 months.The primary outcome measure is retinal ganglion cell-inner plexiform layer thickness at 12 months after treatment.The secondary outcome measures include retinal ganglion cell-inner plexiform layer thickness before and 1,3,6,and 9 months after treatment,retinal nerve fiber layer thickness,best-corrected visual acuity,macular area thickness,and choroidal thickness before and 1,3,6,9,and 12 months after treatment.Safety measure is the incidence of adverse events at 1,3,6,9,and 12 months after treatment.The study protocol hopes to validate the better efficacy and safety of the combined treatment in patients with diabetic macula compared with the other two monotherapies alone during the 12-month follow-up period.The trial is designed to focus on clarifying the time-effect relationship between imaging measures related to the integrity of retinal ganglion cells and best-corrected visual acuity.The trial protocol was approved by the Medical Ethics Committee of the Affiliated Hospital of Beihua University with approval No.(2023)(26)on April 25,2023,and was registered with the Chinese Clinical Trial Registry(registration number:ChiCTR2300072478,June 14,2023,protocol version:2.0). 展开更多
关键词 choroidal thickness diabetic macular edema laser photocoagulation retinal ganglion cell-inner plexiform layer thickness retinal ganglion cells retinal nerve fiber layer thickness thickness of the macular area vascular endothelial growth factor visual acuity
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Fiber Coupling of Laser Diode Bar to M ultimode Fiber Array 被引量:10
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作者 王晓薇 肖建伟 +6 位作者 马骁宇 王仲明 方高瞻 冯小明 刘媛媛 刘斌 张敬明 《Journal of Semiconductors》 EI CAS CSCD 北大核心 2002年第5期464-467,共4页
A piece of multimode optical fiber with a low num er ical aperture (NA) is used as an inexpensive microlens to collimate the output r adiation of a laser diode bar in the high numerical aperture (NA) direction.The em... A piece of multimode optical fiber with a low num er ical aperture (NA) is used as an inexpensive microlens to collimate the output r adiation of a laser diode bar in the high numerical aperture (NA) direction.The emissions of the laser diode bar are coupled into multimode fiber array.The radi ation from individual ones of emitter regions is optically coupled into individu al ones of fiber array.Total coupling efficiency and fiber output power are 75% and 15W,respectively. 展开更多
关键词 fiber coupling laser diode bar multimode fiber array fast axis
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Porosity sensitivity of A356 Al alloy during fiber laser welding 被引量:4
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作者 李凯 芦凤桂 +2 位作者 郭松涛 崔海超 唐新华 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2015年第8期2516-2523,共8页
In order to decrease the metallurgical porosity and keyhole-induced porosity during deep penetration laser welding of Al and its alloys, and increase the mechanical properties of work-piece, the effects of welding par... In order to decrease the metallurgical porosity and keyhole-induced porosity during deep penetration laser welding of Al and its alloys, and increase the mechanical properties of work-piece, the effects of welding parameters such as laser power, welding speed and defocusing value on both kinds of porosities were systemically analyzed respectively, and the shape and fluctuation of plume of the keyhole were observed to reflect the stability of the keyhole. The results show that increasing laser power or decreasing laser spot size can lead to the rising of both number and occupied area of pores in the weld; meanwhile, the plume fluctuates violently over the keyhole, which is always companied with the intense metallic vapor, liquid metal spatter and collapsing in the keyhole, thus more pores are generated in the weld. The porosity in the weld reaches the minimum at welding velocity of 2.0 m/min when laser power is 5 kW and defocusing value is 0. 展开更多
关键词 A356 Al alloy fiber laser welding POROSITY KEYHOLE PLUME
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Stitch welding of Ti-6Al-4V titanium alloy by fiber laser 被引量:3
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作者 李翠 李斌 +3 位作者 吴泽锋 祁小勇 叶兵 王爱华 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2017年第1期91-101,共11页
Stitch welding of plate covered skeleton structure of Ti-6Al-4V titanium alloys has a variety of applications in aerospace vehicle manufacture. The laser stitch welding of Ti-6Al-4V titanium alloys was carried out by ... Stitch welding of plate covered skeleton structure of Ti-6Al-4V titanium alloys has a variety of applications in aerospace vehicle manufacture. The laser stitch welding of Ti-6Al-4V titanium alloys was carried out by a 4 kW ROFIN fiber laser. Influences of laser welding parameters on the macroscopic geometry, porosity, microstructure and mechanical properties of the stitch welded seams were investigated by digital microscope, optical microscope, scanning electron microscope and universal tensile testing machine. The results showed that the three-pipe nozzle with gas flow rate larger than 5 L/min could avoid oxidization, presenting better shielding effect in comparison with the single-pipe nozzle. Porosity formation could be suppressed with the gap between plate and skeleton less than 0.1 mm, while the existing porosity can be reduced with remelting. The maximum shear strength of stitch welding joint with minimal porosity was obtained by employing laser power of 1700 W, welding speed of 1.5 m/min and defocusing distance of +8 ram. 展开更多
关键词 Ti-6Al-4V titanium alloy fiber laser stitch welding welding parameter POROSITY
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