Solutions for radial flow of a Bingham fluid are analyzed in this paper.It aims to eliminate confusions in the literature concerning the plug flow region in different solutions for analysis and design of grouting in r...Solutions for radial flow of a Bingham fluid are analyzed in this paper.It aims to eliminate confusions in the literature concerning the plug flow region in different solutions for analysis and design of grouting in rock fractures.The analyses based on the force balance equation reveal that the plug flow region in Bingham radial flow is independent of the fracture radius,and is not a growth function adapted from the solution of one-dimensional(1D)slit flow according to‘similarity’.Based on the shear stress distribution,we analytically proposed that a non-uniform plug flow region cannot exist.The Bingham fluid(grout)penetration and flowrate evolution as functions of grouting time are given using the correct expression for the plug flow region.The radius-independent plug flow region and the presented flowrate evolution equation are also verified numerically.For radial flow,the relative penetration length is equal to the relative width of plug flow region,which is the same as that for 1D channel flow.Discrepancies in analytical solutions for grout penetration and flowrate evolution were also illustrated.The clarification of the plug flow region and evaluation of discrepancies in analytical solutions presented in this work could simplify modeling and design of grouting in rock engineering applications.展开更多
AIM: To examine the efficacy of the radial flow bioreactor (RFB) as an extracorporeal bioartificial liver (BAL) and the reconstruction of liver organoids using embryonic pig liver cells. METHODS: We reconstructe...AIM: To examine the efficacy of the radial flow bioreactor (RFB) as an extracorporeal bioartificial liver (BAL) and the reconstruction of liver organoids using embryonic pig liver cells. METHODS: We reconstructed the liver organoids using embryonic porcine liver cells in the RFB. We also determined the gestational time window for the optimum growth of embryonic porcine liver cells. Five weeks of gestation was designated as embryonic day (E) 35 and 8 wk of gestation was designated as E56. These cells were cultured for one week before morphological and functional examinations. Moreover, the efficacy of pulsed adminisbation of a high concentration hepatocyte growth factor (HGF) was examined. RESULTS: Both cell growth and function were excellent after harvesting on E35. The pulsed administration of a high concentration of HGF promoted the differentiation and maturation of these fetal hepatic cells. Microscopic examination of organoids in the RFB revealed palisading and showed that bile duct-like structures were well developed, indicating that the organoids were mini livers. Transmission electron microscopy revealed microvilli on the luminal surfaces of bile duct-like structures and junctional complexes, which form the basis of the cytoskeleton of epithelial tissues. Furthermore, strong expression of connexin (Cx) 32, which is the main protein of hepatocyte gap junctions, was observed. With respect to liver function, ammonia detoxification and urea synthesis were shown to be performed effectively. CONCLUSION: Our system can potentially be applied in the fields of BAL and transplantation medicine.展开更多
Due to the increasing global demand for industrial gas, the development of large-scale cryogenic air separation systems has attracted considerable attention in recent years. Increasing the height of the adsorption bed...Due to the increasing global demand for industrial gas, the development of large-scale cryogenic air separation systems has attracted considerable attention in recent years. Increasing the height of the adsorption bed in a vertical radial flow adsorber used in cryogenic air separation systems may efficiently increase the treatment capacity of the air in the adsorber. However, uniformity of the flow distribution of the air inside the adsorber would be deteriorated using the height-increasing method. In order to reduce the non-uniformity of the flow distribution caused by the excessive height of adsorption bed in a vertical radial flow adsorber, a novel parallel connection method is proposed in the present work. The experimental apparatus is designed and constructed; the Computational Fluid Dynamics(CFD) technique is used to develop a CFD-based model, which is used to analyze the flow distribution, the static pressure drop and the radial velocity in the newly designed adsorber. In addition, the geometric parameters of annular flow channels and the adsorption bed thickness of the upper unit in the parallelconnected vertical radial flow adsorber are optimized, so that the upper and lower adsorption units could be penetrated by air simultaneously. Comparisons are made between the height-increasing method and the parallel connection method with the same adsorber height. It is shown that using the parallel connection method could reduce the difference between the maximum and minimum radial static pressure drop by 86.2% and improve the uniformity by 80% compared with those of using the height-increasing method. The optimal thickness ratio of the upper and lower adsorption units is obtained as 0.966, in which case the upper and lower adsorption units could be penetrated by air simultaneously, so that the adsorbents in adsorption space could be used more efficiently.展开更多
In this study, radial flow moving bed reactors for isobutane dehydrogenation have been modeled and simulated heterogeneously based on mass and energy conservation laws. The considered reaction networks in the model ar...In this study, radial flow moving bed reactors for isobutane dehydrogenation have been modeled and simulated heterogeneously based on mass and energy conservation laws. The considered reaction networks in the model are isobutene dehydrogenation as main reaction, and hydrogenolysis, propane dehydrogenation as well as coke formation as side reactions that all occur on the catalyst surface. Then, the process condition has been optimized to produce more isobutene under steady state condition. To prove the accuracy of the considered mathematical model and assumptions, simulation results are compared with the plant data. As a powerful method in the global optimization, the genetic algorithm has been used to optimize the considered objective function. The isobutane conversion and isobutene selectivity under optimal conditions are about 40.1% and 91%, respectively.展开更多
Recently,Zou et al.(2020 a)published a theoretical analysis on the radial flow of a Bingham fluid,where they argued that the classical analysis by Dai and Bird(1981)violates the mass conservation.The present discussio...Recently,Zou et al.(2020 a)published a theoretical analysis on the radial flow of a Bingham fluid,where they argued that the classical analysis by Dai and Bird(1981)violates the mass conservation.The present discussion aims to clarify this conflict between those two studies.It is noted that Zou et al.(2020 a)presumed the gap-wise mass flux is negligible in the mass conservation equation,while Dai and Bird(1981)did not require so in their model,and this is found to be the origin of the conflict.In fact,Dai and Bird(1981)’s model is shown to not violate the mass conservation.Therefore,those two models should be viewed as separate models derived from different perspectives.Details of the major difference between the two models are discussed.展开更多
Mixed convection flow of magnetohydrodynamic(MHD) Jeffrey nanofluid over a radially stretching surface with radiative surface is studied. Radial sheet is considered to be convectively heated. Convective boundary condi...Mixed convection flow of magnetohydrodynamic(MHD) Jeffrey nanofluid over a radially stretching surface with radiative surface is studied. Radial sheet is considered to be convectively heated. Convective boundary conditions through heat and mass are employed. The governing boundary layer equations are transformed into ordinary differential equations. Convergent series solutions of the resulting problems are derived. Emphasis has been focused on studying the effects of mixed convection, thermal radiation, magnetic field and nanoparticles on the velocity, temperature and concentration fields. Numerical values of the physical parameters involved in the problem are computed for the local Nusselt and Sherwood numbers are computed.展开更多
Recently,Hoang et al.(2021)discussed our paper Zou et al.(2020).In our paper,we made a statement that Dai and Bird(1981)’s solution for two-dimensional(2 D)radial Bingham fluid flow between parallel plates violates m...Recently,Hoang et al.(2021)discussed our paper Zou et al.(2020).In our paper,we made a statement that Dai and Bird(1981)’s solution for two-dimensional(2 D)radial Bingham fluid flow between parallel plates violates mass balance.Hoang et al.pointed out that Dai and Bird(1981)’s solution does not violate the mass balance because Dai and Bird(1981)’s solution and our analysis are based on different assumptions,i.e.with consideration of the vertical velocity component in the continuity equation or not,which leads to two different approximation models.In this sense,the mass balance of Dai and Bird(1981)’s solution should not be checked using our solution as a reference.In this reply,we add remarks on the two approximation models and their implication for rock grouting analysis.The discussion by Hoang et al.and this reply are helpful to thoroughly eliminate the existing confusion regarding the two solutions in the rock grouting research community.展开更多
Pseudo three-dimension (P3D) hydraulic fracturing models often overpredict the fracture height for a poorly contained fracture. To solve this problem, a new method is presented in shaping the P3D fracture geometry on ...Pseudo three-dimension (P3D) hydraulic fracturing models often overpredict the fracture height for a poorly contained fracture. To solve this problem, a new method is presented in shaping the P3D fracture geometry on the basis of the fundamental theory and the original 1D fluid flow is replaced with a more representatively radial flow. The distribution of the fluid in the modified fluid field is analyzed and a sound explanation to the problem is given. Due to the consideration of the fluid flow in the vertical direction, the modified model can predict the fracture height much better. To validate the rationality of the radial fluid flow assumption, the distribution of the fluid in the modified fluid field is simulated with the plane potential flow by using finite element method. And the results agree effectively with those from the assumption. Through comparing with the full 3D model, the results show that this new P3D model can be used to aid the fracturing design and predict the fracture height under poorly contained situation.展开更多
Based on the local discontinuous Galerkin methods for time-dependent convection-diffusion systems newly developed by Corkburn and Shu,according to the form of the generalized convection-diffusion equations which model...Based on the local discontinuous Galerkin methods for time-dependent convection-diffusion systems newly developed by Corkburn and Shu,according to the form of the generalized convection-diffusion equations which model the radial porous flow with dispersion and adsorption,a local discontinuous Galerkin method for radial porous flow with dispersion and adsorption was developed,a high order accurary new scheme for radial porous flow is obtained.The presented method was applied to the numerical tests of two cases of radial porous,i.e., the convection-dispersion flow and the convection-dispersion-adsorption flow,the corresponding parts of the numerical results are in good agreement with the published solutions,so the presented method is reliable.Reckoning of the computational cost also shows that the method is practicable.展开更多
This study aims to develop a mathematical analysis for one-dimensional modeling of a radial flow through a production well drilled in a confined aquifer, in the case of steady-state flow conditions. An analytical solu...This study aims to develop a mathematical analysis for one-dimensional modeling of a radial flow through a production well drilled in a confined aquifer, in the case of steady-state flow conditions. An analytical solution has derived from that expression for estimation of drawdowns according to different flowrates. Through that process, the evaluation of static pressure, the calculation of hydraulic charge due to the waterflow through the well is evaluated, the drawdowns curves are drawn and at last, the obtained curves are analyzed. The curves obtained for the different flow rates have an asymptotic direction, the axis of the hydraulic charges. The variation of the hydraulic charge depends on the radial distance for different flow rates. The P point, is a common point of all curves obtained for different production flowrates in the well. This point is where the well production flowrate is optimum for the optimal hydraulic charge.展开更多
Due to the controllable and reversible properties of the smart magnetorheological (MR) fluid,a novel multiple radial MR valve was developed. The fluid flowchannels of the proposed MR valve were mainly composed of tw...Due to the controllable and reversible properties of the smart magnetorheological (MR) fluid,a novel multiple radial MR valve was developed. The fluid flowchannels of the proposed MR valve were mainly composed of two annular fluid flowchannels,four radial fluid flow channels and three centric pipe fluid flowchannels. The working principle of the multiple radial MR valve was introduced in detail,and the structure optimization design was carried out using ANSYS software to obtain the optimal structure parameters. Moreover,the optimized MR valve was compared with preoptimized MR valve in terms of their magnetic flux density of radial fluid resistance gap and performance of pressure drop. The experimental test rig was set up to investigate the performance of pressure drop of the proposed MR valve under different currents applied and different loading cases. The results showthat the pressure drop between the inlet and outlet port could reach 5. 77 MPa at the applied current of 0. 8 A. Furthermore,the experimental results also indicate that the loading cases had no effect on the performance of pressure drop.展开更多
AIM: To develop the effective technology for reconstruction of a liver organ in vitro using a bio-artificial liver. METHODS: We previously reported that a radial-flow bioreactor (RFB) could provide a three-dimensi...AIM: To develop the effective technology for reconstruction of a liver organ in vitro using a bio-artificial liver. METHODS: We previously reported that a radial-flow bioreactor (RFB) could provide a three-dimensional highdensity culture system. We presently reconstructed the liver organoid using a functional human hepatocellular carcinoma cell line (FLC-5) as hepatocytes together with mouse immortalized sinusoidal endothelial cell (SEC) line M1 and mouse immortalized hepatic stellate cell (HSC) line A7 as non parenchymal cells in the RFB. Two × 10^7 FLC-5 cells were incubated in the RFB. After 5 d, 2 × 10^7 A7 cells were added in a similar manner followed by another addition of 10^7 M1 cells 5 d later. After three days of perfusion, some cellulose beads with the adherent cells were harvested. The last incubation period included perfusion with 200 nmol/L swinholide A for 2 h and then the remaining cellulose beads along with adherent cells were harvested from the RFB. The cell morphology was observed by transmission electron microscopy (TEM) and scanning electron microscopy (SEM). To assess hepatocyte function, we compared mRNA expression for urea cycle enzymes as well as albumin synthesis by FLC-5 in monolayer cultures compared to those of single-type cultures and cocultures in the RFB. RESULTS: By transmission electron microscopy, FLC-5, M1, and A7 were arranged in relation to the perfusion side in a liver-like organization. Structures resembling bile canaliculi were seen between FCL-5 cells. Scanning electron microscopy demonstrated fenestrae on SEC surfaces. The number of vesiculo-vacuolar organelles (WO) and fenestrae increased when we introduced the actin-binding agent swinholide-A in the RFB for 2h. With respect to liver function, urea was found in the medium, and expression of mRNAs encoding arginosuccinate synthetase and arginase increased when the three cell types were cocultured in the RFB. However, albumin synthesis decreased. CONCLUSION: Co-culture in the RFB system can dramatically change the structure and function of all cell types, including the functional characteristics of hepatocytes. Our system proves effective for reconstruction of a liver organoid using a bio-artificial liver.展开更多
The paper refers to the behavior of a vaneless diffuser of a radial flow pump in partial flow operating conditions. Some experimental data have been obtained using 2D/2C PIV and unsteady pressure measurements within t...The paper refers to the behavior of a vaneless diffuser of a radial flow pump in partial flow operating conditions. Some experimental data have been obtained using 2D/2C PIV and unsteady pressure measurements within the diffuser, in various operating conditions. The experimental results at the lower flow rate are compared with two-dimensional numerical calculations.展开更多
Air flow distribution in radial flow adsorber was numerically investigated using computational fluid dynamics(CFD)method,which was proved to be applicable to study the problem of non-uniform distribution in radial flo...Air flow distribution in radial flow adsorber was numerically investigated using computational fluid dynamics(CFD)method,which was proved to be applicable to study the problem of non-uniform distribution in radial flow adsorber.Results showed that the degree of non-uniformity was more serious in desorption process than that is adsorption process.Therefore,it was considered that the non-uniform distribution of flow in a radial flow adsorber was mainly manifested in the desorption process.Optimum design of distributor parameters can improve the flow distribution in adsorber.Meanwhile,three different structures of distributor and the effect of breathing valve were analyzed.Results revealed that truncated cone is more effective than tubular and conical distributors in flow distribution.By inserting the truncated cone in central channel,desorption uniformity was increased by 6.56%and the breakthrough time of CO_(2)was extended from 564s to 1138s in the adsorption process.The“dead zone”problem at the top of adsorber during the desorption process was solved by opening breathing valve,which prolonged the working life of adsorber and was proved to have less effect on the uniform of airflow.展开更多
Nanofluids are considered as interesting alternatives to conventional coolants. It is well known that traditional fluids have limited heat transfer capabilities when compared to common metals. It is therefore quite co...Nanofluids are considered as interesting alternatives to conventional coolants. It is well known that traditional fluids have limited heat transfer capabilities when compared to common metals. It is therefore quite conceivable that a small amount of extremely fine metallic particles placed in suspension in traditional fluids will considerably increase their heat transfer performances. A numerical investigation into the heat transfer enhancement capabilities of coolants with suspended metallic nanoparticles inside a radial, laminar flow cooling configuration is presented. Temperature dependant nanofluid properties are evaluated from experimental data available in recent literature. Results indicate that considerable heat transfer increases are possible with the use of relatively small volume fractions of nanoparticles. Generally, however, these are accompanied by considerable increases in wall shear-stress. Results also show that predictions obtained with temperature variable nanofluid properties yield greater heat transfer capabilities and lower wall shear stresses when compared to predictions using constant properties.展开更多
This paper investigates the near-field performance of chemical dissolution-front instability(CDFI) around a circular acidinjection-well in fluid-saturated porous media(FSPM) through using purely mathematical deduction...This paper investigates the near-field performance of chemical dissolution-front instability(CDFI) around a circular acidinjection-well in fluid-saturated porous media(FSPM) through using purely mathematical deductions.After the mathematical governing equations of the CDFI problem involving radially divergent flow are briefly described,both analytical base solutions and perturbation solutions for the considered problem are mathematically derived.These analytical solutions lead to the theoretical expression of the perturbation induced dimensionless growth-rate and the following two new findings.The first new finding is that the critical Peclet number of a chemical dissolution system(CDS) associated with radially divergent flow in FSPM is not only a function of the permeability ratio between the undissolved and dissolved regions as well as the dimensionless wavenumber,but also a function of the circular chemical dissolution-front location relative to the circular acid-injection-well in FSPM.The second new finding is that as the direct result of considering a nonzero radius of the circular acid-injection-well,there exits a critical closeness number,which may be used to assess where the circular chemical dissolution-front starts becoming unstable in the CDS associated with radially divergent flow.Based on these two new findings,a theoretical criterion of two parts has been established.The first part of the established theoretical criterion answers the scientific question when a circular chemical dissolution-front can become unstable,while the second part of the established theoretical criterion answers the scientific question where a circular chemical dissolution-front can become unstable.Through applying the established theoretical criterion,a long-term existing mystery why the wormhole pattern of fractal nature and the compact pattern of fingering nature are formed at different locations away from the circular acid-injection-well circumference in fluid-saturated carbonate rocks has been successfully revealed.展开更多
The effects of blade lean and vortex design on the aerodynamics of a turbine entry nozzle guide vane (NGV) are considered using computational fluid dynamics. The aim of the work is to address some of the uncertainti...The effects of blade lean and vortex design on the aerodynamics of a turbine entry nozzle guide vane (NGV) are considered using computational fluid dynamics. The aim of the work is to address some of the uncertainties which have arisen from previous studies where conflicting results have been reported for the effect on the NGV. The configuration was initially based on the energy efficient engine turbine which also served as the validation case for the computational method. A total of 17 NGV configurations were evaluated to study the effects of lean and vortex design on row efficiency and secondary kinetic energy. The distribution of mass flow ratio is introduced as an additional factor in the assessment of blade lean effects. The results show that in the turbine entry NGV, the secondary flow strength is not a dominant factor that determines NGV losses and therefore the changes of loading distribution due to blade lean and the associated loss mecha- nisms should be regarded as a key factor. Radial mass flow redistribution under different NGV lean and twist is demonstrated as an addition key factor influencin~ row efficiency.展开更多
Long term ground movements above a tunnel may continue to increase with time after tunnelling in clayey soils as the tunnellinginduced excess pore water pressures dissipate,whilst the changing earth pressure acting on...Long term ground movements above a tunnel may continue to increase with time after tunnelling in clayey soils as the tunnellinginduced excess pore water pressures dissipate,whilst the changing earth pressure acting on the tunnel leads to further tunnel deformation during consolidation.Furthermore the tunnel itself introduces new drainage conditions;that is,depending on the drainage condition of the tunnel lining,the effective stresses around the tunnel change with time,inducing further soil consolidation.A seepage rate from low permeability clayey soil is often very small and the groundwater seeping into the tunnel can evaporate quickly.Although a tunnel may look impermeable because the surface looks dry,it is possible that the tunnel drainage conditions are actually permeable.This paper summarises the investigation of soil-tunnel consolidation interaction,particularly focusing on ground surface movements and tunnel lining deformation in the interest of engineering concerns.Analysis results show that tunnel lining permittivity relative to the permeability of the surrounding ground plays an important role on both long-term ground movements as well as tunnel lining behaviour.The findings published in literature are reviewed step by step starting from a single tunnel,twin tunnels to complex cross passage structures.The mechanisms of tunnelling-induced soil consolidation for these structures are identified and,where applicable,possible engineering methodologies to assess the magnitude of long-term ground surface settlements and tunnel lining loads are proposed.展开更多
基金funding for this study is provided by the BeFo Rock Engineering Research Foundation(Grant No.392)。
文摘Solutions for radial flow of a Bingham fluid are analyzed in this paper.It aims to eliminate confusions in the literature concerning the plug flow region in different solutions for analysis and design of grouting in rock fractures.The analyses based on the force balance equation reveal that the plug flow region in Bingham radial flow is independent of the fracture radius,and is not a growth function adapted from the solution of one-dimensional(1D)slit flow according to‘similarity’.Based on the shear stress distribution,we analytically proposed that a non-uniform plug flow region cannot exist.The Bingham fluid(grout)penetration and flowrate evolution as functions of grouting time are given using the correct expression for the plug flow region.The radius-independent plug flow region and the presented flowrate evolution equation are also verified numerically.For radial flow,the relative penetration length is equal to the relative width of plug flow region,which is the same as that for 1D channel flow.Discrepancies in analytical solutions for grout penetration and flowrate evolution were also illustrated.The clarification of the plug flow region and evaluation of discrepancies in analytical solutions presented in this work could simplify modeling and design of grouting in rock engineering applications.
基金Supported by Grants-In-Aid from the University Start-Up Creation Support Systemthe Promotion and Mutual Aid Corporation for Private School of Japanthe Japan Health Sciences Foundation, Research on Health Science on Drug Innovation, No. KH 71068
文摘AIM: To examine the efficacy of the radial flow bioreactor (RFB) as an extracorporeal bioartificial liver (BAL) and the reconstruction of liver organoids using embryonic pig liver cells. METHODS: We reconstructed the liver organoids using embryonic porcine liver cells in the RFB. We also determined the gestational time window for the optimum growth of embryonic porcine liver cells. Five weeks of gestation was designated as embryonic day (E) 35 and 8 wk of gestation was designated as E56. These cells were cultured for one week before morphological and functional examinations. Moreover, the efficacy of pulsed adminisbation of a high concentration hepatocyte growth factor (HGF) was examined. RESULTS: Both cell growth and function were excellent after harvesting on E35. The pulsed administration of a high concentration of HGF promoted the differentiation and maturation of these fetal hepatic cells. Microscopic examination of organoids in the RFB revealed palisading and showed that bile duct-like structures were well developed, indicating that the organoids were mini livers. Transmission electron microscopy revealed microvilli on the luminal surfaces of bile duct-like structures and junctional complexes, which form the basis of the cytoskeleton of epithelial tissues. Furthermore, strong expression of connexin (Cx) 32, which is the main protein of hepatocyte gap junctions, was observed. With respect to liver function, ammonia detoxification and urea synthesis were shown to be performed effectively. CONCLUSION: Our system can potentially be applied in the fields of BAL and transplantation medicine.
基金Supported by the National Key R&D Program of China(2017YFB0603702)the Natural Science Foundation of Zhejiang Province(Y15E060014)+1 种基金the National Natural Science Foundation of China(51636007)Shanghai Young Teachers Development Program(10-16-301-801)
文摘Due to the increasing global demand for industrial gas, the development of large-scale cryogenic air separation systems has attracted considerable attention in recent years. Increasing the height of the adsorption bed in a vertical radial flow adsorber used in cryogenic air separation systems may efficiently increase the treatment capacity of the air in the adsorber. However, uniformity of the flow distribution of the air inside the adsorber would be deteriorated using the height-increasing method. In order to reduce the non-uniformity of the flow distribution caused by the excessive height of adsorption bed in a vertical radial flow adsorber, a novel parallel connection method is proposed in the present work. The experimental apparatus is designed and constructed; the Computational Fluid Dynamics(CFD) technique is used to develop a CFD-based model, which is used to analyze the flow distribution, the static pressure drop and the radial velocity in the newly designed adsorber. In addition, the geometric parameters of annular flow channels and the adsorption bed thickness of the upper unit in the parallelconnected vertical radial flow adsorber are optimized, so that the upper and lower adsorption units could be penetrated by air simultaneously. Comparisons are made between the height-increasing method and the parallel connection method with the same adsorber height. It is shown that using the parallel connection method could reduce the difference between the maximum and minimum radial static pressure drop by 86.2% and improve the uniformity by 80% compared with those of using the height-increasing method. The optimal thickness ratio of the upper and lower adsorption units is obtained as 0.966, in which case the upper and lower adsorption units could be penetrated by air simultaneously, so that the adsorbents in adsorption space could be used more efficiently.
文摘In this study, radial flow moving bed reactors for isobutane dehydrogenation have been modeled and simulated heterogeneously based on mass and energy conservation laws. The considered reaction networks in the model are isobutene dehydrogenation as main reaction, and hydrogenolysis, propane dehydrogenation as well as coke formation as side reactions that all occur on the catalyst surface. Then, the process condition has been optimized to produce more isobutene under steady state condition. To prove the accuracy of the considered mathematical model and assumptions, simulation results are compared with the plant data. As a powerful method in the global optimization, the genetic algorithm has been used to optimize the considered objective function. The isobutane conversion and isobutene selectivity under optimal conditions are about 40.1% and 91%, respectively.
基金financially supported by Yeungnam University Research Grant Program 2019。
文摘Recently,Zou et al.(2020 a)published a theoretical analysis on the radial flow of a Bingham fluid,where they argued that the classical analysis by Dai and Bird(1981)violates the mass conservation.The present discussion aims to clarify this conflict between those two studies.It is noted that Zou et al.(2020 a)presumed the gap-wise mass flux is negligible in the mass conservation equation,while Dai and Bird(1981)did not require so in their model,and this is found to be the origin of the conflict.In fact,Dai and Bird(1981)’s model is shown to not violate the mass conservation.Therefore,those two models should be viewed as separate models derived from different perspectives.Details of the major difference between the two models are discussed.
文摘Mixed convection flow of magnetohydrodynamic(MHD) Jeffrey nanofluid over a radially stretching surface with radiative surface is studied. Radial sheet is considered to be convectively heated. Convective boundary conditions through heat and mass are employed. The governing boundary layer equations are transformed into ordinary differential equations. Convergent series solutions of the resulting problems are derived. Emphasis has been focused on studying the effects of mixed convection, thermal radiation, magnetic field and nanoparticles on the velocity, temperature and concentration fields. Numerical values of the physical parameters involved in the problem are computed for the local Nusselt and Sherwood numbers are computed.
文摘Recently,Hoang et al.(2021)discussed our paper Zou et al.(2020).In our paper,we made a statement that Dai and Bird(1981)’s solution for two-dimensional(2 D)radial Bingham fluid flow between parallel plates violates mass balance.Hoang et al.pointed out that Dai and Bird(1981)’s solution does not violate the mass balance because Dai and Bird(1981)’s solution and our analysis are based on different assumptions,i.e.with consideration of the vertical velocity component in the continuity equation or not,which leads to two different approximation models.In this sense,the mass balance of Dai and Bird(1981)’s solution should not be checked using our solution as a reference.In this reply,we add remarks on the two approximation models and their implication for rock grouting analysis.The discussion by Hoang et al.and this reply are helpful to thoroughly eliminate the existing confusion regarding the two solutions in the rock grouting research community.
文摘Pseudo three-dimension (P3D) hydraulic fracturing models often overpredict the fracture height for a poorly contained fracture. To solve this problem, a new method is presented in shaping the P3D fracture geometry on the basis of the fundamental theory and the original 1D fluid flow is replaced with a more representatively radial flow. The distribution of the fluid in the modified fluid field is analyzed and a sound explanation to the problem is given. Due to the consideration of the fluid flow in the vertical direction, the modified model can predict the fracture height much better. To validate the rationality of the radial fluid flow assumption, the distribution of the fluid in the modified fluid field is simulated with the plane potential flow by using finite element method. And the results agree effectively with those from the assumption. Through comparing with the full 3D model, the results show that this new P3D model can be used to aid the fracturing design and predict the fracture height under poorly contained situation.
文摘Based on the local discontinuous Galerkin methods for time-dependent convection-diffusion systems newly developed by Corkburn and Shu,according to the form of the generalized convection-diffusion equations which model the radial porous flow with dispersion and adsorption,a local discontinuous Galerkin method for radial porous flow with dispersion and adsorption was developed,a high order accurary new scheme for radial porous flow is obtained.The presented method was applied to the numerical tests of two cases of radial porous,i.e., the convection-dispersion flow and the convection-dispersion-adsorption flow,the corresponding parts of the numerical results are in good agreement with the published solutions,so the presented method is reliable.Reckoning of the computational cost also shows that the method is practicable.
文摘This study aims to develop a mathematical analysis for one-dimensional modeling of a radial flow through a production well drilled in a confined aquifer, in the case of steady-state flow conditions. An analytical solution has derived from that expression for estimation of drawdowns according to different flowrates. Through that process, the evaluation of static pressure, the calculation of hydraulic charge due to the waterflow through the well is evaluated, the drawdowns curves are drawn and at last, the obtained curves are analyzed. The curves obtained for the different flow rates have an asymptotic direction, the axis of the hydraulic charges. The variation of the hydraulic charge depends on the radial distance for different flow rates. The P point, is a common point of all curves obtained for different production flowrates in the well. This point is where the well production flowrate is optimum for the optimal hydraulic charge.
基金Supported by the National Natural Science Foundation of China(51475165,11462004)the Jiangxi Provincial Foundation for Leaders of Academic and Disciplines in Science(20162BCB22019)5511 Science and Technology Innovation Talent Project of Jiangxi Province(20165BCB18011)
文摘Due to the controllable and reversible properties of the smart magnetorheological (MR) fluid,a novel multiple radial MR valve was developed. The fluid flowchannels of the proposed MR valve were mainly composed of two annular fluid flowchannels,four radial fluid flow channels and three centric pipe fluid flowchannels. The working principle of the multiple radial MR valve was introduced in detail,and the structure optimization design was carried out using ANSYS software to obtain the optimal structure parameters. Moreover,the optimized MR valve was compared with preoptimized MR valve in terms of their magnetic flux density of radial fluid resistance gap and performance of pressure drop. The experimental test rig was set up to investigate the performance of pressure drop of the proposed MR valve under different currents applied and different loading cases. The results showthat the pressure drop between the inlet and outlet port could reach 5. 77 MPa at the applied current of 0. 8 A. Furthermore,the experimental results also indicate that the loading cases had no effect on the performance of pressure drop.
基金Supported by grants-in-aid from the University Start-Up Creation Support System,the Promotion and Mutual Aid Corporation for Private Schools of JapanThe Japan Health Sciences Foundation(Research on Health Sciences on Drug Innovation,KH71068)
文摘AIM: To develop the effective technology for reconstruction of a liver organ in vitro using a bio-artificial liver. METHODS: We previously reported that a radial-flow bioreactor (RFB) could provide a three-dimensional highdensity culture system. We presently reconstructed the liver organoid using a functional human hepatocellular carcinoma cell line (FLC-5) as hepatocytes together with mouse immortalized sinusoidal endothelial cell (SEC) line M1 and mouse immortalized hepatic stellate cell (HSC) line A7 as non parenchymal cells in the RFB. Two × 10^7 FLC-5 cells were incubated in the RFB. After 5 d, 2 × 10^7 A7 cells were added in a similar manner followed by another addition of 10^7 M1 cells 5 d later. After three days of perfusion, some cellulose beads with the adherent cells were harvested. The last incubation period included perfusion with 200 nmol/L swinholide A for 2 h and then the remaining cellulose beads along with adherent cells were harvested from the RFB. The cell morphology was observed by transmission electron microscopy (TEM) and scanning electron microscopy (SEM). To assess hepatocyte function, we compared mRNA expression for urea cycle enzymes as well as albumin synthesis by FLC-5 in monolayer cultures compared to those of single-type cultures and cocultures in the RFB. RESULTS: By transmission electron microscopy, FLC-5, M1, and A7 were arranged in relation to the perfusion side in a liver-like organization. Structures resembling bile canaliculi were seen between FCL-5 cells. Scanning electron microscopy demonstrated fenestrae on SEC surfaces. The number of vesiculo-vacuolar organelles (WO) and fenestrae increased when we introduced the actin-binding agent swinholide-A in the RFB for 2h. With respect to liver function, urea was found in the medium, and expression of mRNAs encoding arginosuccinate synthetase and arginase increased when the three cell types were cocultured in the RFB. However, albumin synthesis decreased. CONCLUSION: Co-culture in the RFB system can dramatically change the structure and function of all cell types, including the functional characteristics of hepatocytes. Our system proves effective for reconstruction of a liver organoid using a bio-artificial liver.
文摘The paper refers to the behavior of a vaneless diffuser of a radial flow pump in partial flow operating conditions. Some experimental data have been obtained using 2D/2C PIV and unsteady pressure measurements within the diffuser, in various operating conditions. The experimental results at the lower flow rate are compared with two-dimensional numerical calculations.
基金The project is funded by the Fundamental Research Funds for the Central Universities with No.3082017NS2017005.
文摘Air flow distribution in radial flow adsorber was numerically investigated using computational fluid dynamics(CFD)method,which was proved to be applicable to study the problem of non-uniform distribution in radial flow adsorber.Results showed that the degree of non-uniformity was more serious in desorption process than that is adsorption process.Therefore,it was considered that the non-uniform distribution of flow in a radial flow adsorber was mainly manifested in the desorption process.Optimum design of distributor parameters can improve the flow distribution in adsorber.Meanwhile,three different structures of distributor and the effect of breathing valve were analyzed.Results revealed that truncated cone is more effective than tubular and conical distributors in flow distribution.By inserting the truncated cone in central channel,desorption uniformity was increased by 6.56%and the breakthrough time of CO_(2)was extended from 564s to 1138s in the adsorption process.The“dead zone”problem at the top of adsorber during the desorption process was solved by opening breathing valve,which prolonged the working life of adsorber and was proved to have less effect on the uniform of airflow.
文摘Nanofluids are considered as interesting alternatives to conventional coolants. It is well known that traditional fluids have limited heat transfer capabilities when compared to common metals. It is therefore quite conceivable that a small amount of extremely fine metallic particles placed in suspension in traditional fluids will considerably increase their heat transfer performances. A numerical investigation into the heat transfer enhancement capabilities of coolants with suspended metallic nanoparticles inside a radial, laminar flow cooling configuration is presented. Temperature dependant nanofluid properties are evaluated from experimental data available in recent literature. Results indicate that considerable heat transfer increases are possible with the use of relatively small volume fractions of nanoparticles. Generally, however, these are accompanied by considerable increases in wall shear-stress. Results also show that predictions obtained with temperature variable nanofluid properties yield greater heat transfer capabilities and lower wall shear stresses when compared to predictions using constant properties.
基金supported by the National Natural Science Foundation of China (Grant Nos.42030809 and 72088101)。
文摘This paper investigates the near-field performance of chemical dissolution-front instability(CDFI) around a circular acidinjection-well in fluid-saturated porous media(FSPM) through using purely mathematical deductions.After the mathematical governing equations of the CDFI problem involving radially divergent flow are briefly described,both analytical base solutions and perturbation solutions for the considered problem are mathematically derived.These analytical solutions lead to the theoretical expression of the perturbation induced dimensionless growth-rate and the following two new findings.The first new finding is that the critical Peclet number of a chemical dissolution system(CDS) associated with radially divergent flow in FSPM is not only a function of the permeability ratio between the undissolved and dissolved regions as well as the dimensionless wavenumber,but also a function of the circular chemical dissolution-front location relative to the circular acid-injection-well in FSPM.The second new finding is that as the direct result of considering a nonzero radius of the circular acid-injection-well,there exits a critical closeness number,which may be used to assess where the circular chemical dissolution-front starts becoming unstable in the CDS associated with radially divergent flow.Based on these two new findings,a theoretical criterion of two parts has been established.The first part of the established theoretical criterion answers the scientific question when a circular chemical dissolution-front can become unstable,while the second part of the established theoretical criterion answers the scientific question where a circular chemical dissolution-front can become unstable.Through applying the established theoretical criterion,a long-term existing mystery why the wormhole pattern of fractal nature and the compact pattern of fingering nature are formed at different locations away from the circular acid-injection-well circumference in fluid-saturated carbonate rocks has been successfully revealed.
基金the support of Cranfield University and China Aviation Powerplant Research Institute of AVIC
文摘The effects of blade lean and vortex design on the aerodynamics of a turbine entry nozzle guide vane (NGV) are considered using computational fluid dynamics. The aim of the work is to address some of the uncertainties which have arisen from previous studies where conflicting results have been reported for the effect on the NGV. The configuration was initially based on the energy efficient engine turbine which also served as the validation case for the computational method. A total of 17 NGV configurations were evaluated to study the effects of lean and vortex design on row efficiency and secondary kinetic energy. The distribution of mass flow ratio is introduced as an additional factor in the assessment of blade lean effects. The results show that in the turbine entry NGV, the secondary flow strength is not a dominant factor that determines NGV losses and therefore the changes of loading distribution due to blade lean and the associated loss mecha- nisms should be regarded as a key factor. Radial mass flow redistribution under different NGV lean and twist is demonstrated as an addition key factor influencin~ row efficiency.
基金This work was supported by National Natural Science Foundation of China(No.51508403)by National Natural Science Foundation of China(No.51608539).
文摘Long term ground movements above a tunnel may continue to increase with time after tunnelling in clayey soils as the tunnellinginduced excess pore water pressures dissipate,whilst the changing earth pressure acting on the tunnel leads to further tunnel deformation during consolidation.Furthermore the tunnel itself introduces new drainage conditions;that is,depending on the drainage condition of the tunnel lining,the effective stresses around the tunnel change with time,inducing further soil consolidation.A seepage rate from low permeability clayey soil is often very small and the groundwater seeping into the tunnel can evaporate quickly.Although a tunnel may look impermeable because the surface looks dry,it is possible that the tunnel drainage conditions are actually permeable.This paper summarises the investigation of soil-tunnel consolidation interaction,particularly focusing on ground surface movements and tunnel lining deformation in the interest of engineering concerns.Analysis results show that tunnel lining permittivity relative to the permeability of the surrounding ground plays an important role on both long-term ground movements as well as tunnel lining behaviour.The findings published in literature are reviewed step by step starting from a single tunnel,twin tunnels to complex cross passage structures.The mechanisms of tunnelling-induced soil consolidation for these structures are identified and,where applicable,possible engineering methodologies to assess the magnitude of long-term ground surface settlements and tunnel lining loads are proposed.