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Minimum Amount of Extracting Solvent of a Separation of Two Rare Earth Components 被引量:2
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作者 Fuxiang Cheng Sheng Wu +4 位作者 Yan Liu Songling Wang Bo Zhang Chunsheng Liao Chunhua Yan 《Advances in Materials Physics and Chemistry》 2014年第12期275-283,共9页
A significant development in the theory of countercurrent extraction will be presented in this article. New expressions of the term in countercurrent extraction process analysis, “Adjacent Stage Impurity Ratio” (ASI... A significant development in the theory of countercurrent extraction will be presented in this article. New expressions of the term in countercurrent extraction process analysis, “Adjacent Stage Impurity Ratio” (ASIR), are deduced. Furthermore, based on the term together with mass balance and extraction equilibrium, the conditions where a given countercurrent extraction separation operation can have minimum amounts of both extracting solvent and scrubbing agent solution can be estimated, and the equations of the two minimum amounts can be deduced. It was found that the equations for a two-component separation using a single aqueous or organic feed are exactly the same as they appeared in the theory initially established in 1970s. Unlike its earlier version, the present derivation does not involve feed-stage-composition hypothesis, and also has the advantage of dealing with a double-feed system where both aqueous and organic feeds are simultaneously employed whereas the earlier theory can only analyze a separation using a single aqueous or organic feed. 展开更多
关键词 Theory of Countercurrent Extraction Minimum AMOUNT of EXTRACTING SOLVENT TWO-componENT SEPAratioN Adjacent Stage IMPURITY ratio
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Ion adsorption components in liquid/solid systems 被引量:21
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作者 WU Xiao-fu HU Yue-li ZHAO Fang HUANG Zhong-zi LEI Dian 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2006年第6期1167-1175,共9页
Experiments on Zn^2+ and Cd^2+ adsorptions on vermiculite in aqueous solutions were conducted to investigate the widely observed adsorbent concentration effect on the traditionally defined adsorption isotherm in the... Experiments on Zn^2+ and Cd^2+ adsorptions on vermiculite in aqueous solutions were conducted to investigate the widely observed adsorbent concentration effect on the traditionally defined adsorption isotherm in the adsorbate range 25--500 mg/L and adsorbent range 10--150 g/L. The results showed that the equilibrium ion adsorption density did not correspond to a unique equilibrium ion concentration in liquid phase. Three adsorbate/adsorbent ratios, the equilibrium adsorption density, the ratio of equilibrium adsorbate concentration in liquid phase to adsorbent concentration, and the ratio of initial adsorbate concentration to adsorbent concentration, were found to be related with unique values in the tested range. Based on the assumption that the equilibrium state of a liquid/solid adsorption system is determined by four mutually related components: adsorbate in liquid phase, adsorbate in solid phase, uncovered adsorption site and covered adsorption site, and that the equilibrium chemical potentials of these components should be equalized, a new model was presented for describing ion adsorption isotherm in liquid/solid systems. The proposed model fit well the experimental data obtained from the examined samples. 展开更多
关键词 adsorbent effect adsorbate/adsorbent ratio adsorption component chemical potential Zn^2+ Cd^2+ VERMICULITE
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Judgment of Aroma Types of Middle and Upper Flue-cured Tobacco Leaves Based on Proportions of Aroma Components 被引量:3
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作者 詹军 周芳芳 +5 位作者 包崇彦 毛春堂 邓国宾 王伟 杨俊 张晓龙 《Agricultural Science & Technology》 CAS 2013年第4期612-619,共8页
[Objective] This study aimed to establish mathematical models for judging the aroma types of flue-cured tobacco leaves from the upper and middle parts of plants. [Method] A total of 128 samples (63 C3F and 65 B2F) f... [Objective] This study aimed to establish mathematical models for judging the aroma types of flue-cured tobacco leaves from the upper and middle parts of plants. [Method] A total of 128 samples (63 C3F and 65 B2F) from 11 main tobac- co production provinces of China were selected as materials. Stepwise discriminant analysis was applied to samples with different aroma types and discriminant function was expressed with the proportions of 67 aroma components in total aroma con- stituents as the index. [Result] The ratio of most aroma components in clear and full aroma tobacco leaves was higher than that in middle aroma leaves. The ratios of 51, 43 and 40 aroma components of clear, middle and full aroma tobaccos were higher in upper leaves than that in middle leaves. Aroma components dominated certain aroma types differed between middle and upper leaves. The proportions of 18 and 11 aroma components in upper and middle leaves were led in the stepwise discriminant function respectively. Self-validation and cross-validation methods were applied to evaluate the original samples, and the accuracy rates reached 100% and 98.6% on middle leaves, 96.37% and 94.4% on upper leaves. The accuracy rates on some other samples reached 100% on middle leaves and 91.7% on upper leaves predicted with the model. [Conclusion] The ratio of aroma components as discriminant index could improve discriminant accuracy significantly in the middle and upper leaves. It could be used to analyze aroma types objectively, accurately and quickly. 展开更多
关键词 Flue-cured tobacco Aroma components Middle leaves Upper leaves ratio Aroma types Discriminant analysis
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Component Matching Based on Low Bypass Ratio Mixed Exhaust Turbofan Engine
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作者 Zheng Xilong Wu Tieying Ji Honghu 《Transactions of Nanjing University of Aeronautics and Astronautics》 EI CSCD 2018年第S1期9-15,共7页
In order to study component matching which exists in off-design situation at the initial design stage of turbine engine,by establishing performance analysis model of low bypass ratio mixed flow turbofan engine and com... In order to study component matching which exists in off-design situation at the initial design stage of turbine engine,by establishing performance analysis model of low bypass ratio mixed flow turbofan engine and components characteristic data,and by applying Newton-Raphson method to solve the nonlinear equations of offdesign points in flying envelop,the factors which affect matching between engine components are studied.The results show that low pressure turbine(LPT)must not operate in a critical condition,and the partial derivative(slope)of pressure ratio to similitude mass flow ratio of working point in LPT characteristic map affects the stability of engine.The smaller the slope is,the more stable the engine is.In addition,the engine is more stable when the fan characteristic map is steep. 展开更多
关键词 turbofan engine LOW BYPASS ratio OFF-DESIGN componENT MATCHING OOP performance analysis
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A Quantitative Factorial Component Analysis to Investigate the Recent Changes of Japan’s Weight-Based Food Self-Sufficiency Ratio 被引量:1
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作者 Kunihisa Yoshii Tatsuo Oyama 《American Journal of Operations Research》 2016年第1期44-60,共17页
We investigate the weight-based food self-sufficiency ratio (WSSR) for Japan over a 50-year period (1961-2011) by applying factorial component analysis technique in order to measure the changes of the WSSR quantitativ... We investigate the weight-based food self-sufficiency ratio (WSSR) for Japan over a 50-year period (1961-2011) by applying factorial component analysis technique in order to measure the changes of the WSSR quantitatively. Quantitative data analysis is employed to determine the drivers of those changes. Numerical results show that Japan experienced a drastic decline in its food self-sufficiency ratio (FSSR) during the above period. The factorial component analysis shows that such a decline was caused by the changes in the FSSR of the food groups/items, not in the quantity of the food supply. A number of characteristics of those changes are presented and a list of major food groups that have major impacts on the changes is constructed. The findings in this paper reiterate the alarming food security problem in Japan and provide clear insight into the causes of this problem. The findings in this study pick up where previous studies have left off, aid the food-related policy-making process and identify new ideas for future food research. 展开更多
关键词 Food Self-Sufficiency ratio Food Security Factorial component Analysis
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Improved Performance of Fault Detection Based on Selection of the Optimal Number of Principal Components 被引量:1
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作者 LI Yuan TANG Xiao-Chu 《自动化学报》 EI CSCD 北大核心 2009年第12期1550-1557,共8页
关键词 故障检测 故障信号 敏感性 信噪比 计算机技术
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Yields,growth and water use under chemical topping in relations to row configuration and plant density in drip-irrigated cotton 被引量:1
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作者 Wang Xuejiao Hu Yanping +10 位作者 Ji Chunrong Chen Yongfan Sun Shuai Zhang Zeshan Zhang Yutong Wang Sen Yang Mingfeng Ji Fen Guo Yanyun Li Jie Zhang Lizhen 《Journal of Cotton Research》 CAS 2024年第2期123-136,共14页
Background Water deficit is an important problem in agricultural production in arid regions.With the advent of wholly mechanized technology for cotton planting in Xinjiang,it is important to determine which planting m... Background Water deficit is an important problem in agricultural production in arid regions.With the advent of wholly mechanized technology for cotton planting in Xinjiang,it is important to determine which planting mode could achieve high yield,fiber quality and water use efficiency(WUE).This study aimed to explore if chemical topping affected cotton yield,quality and water use in relation to row configuration and plant densities.Results Experiments were carried out in Xinjiang China,in 2020 and 2021 with two topping method,manual topping and chemical topping,two plant densities,low and high,and two row configurations,i.e.,76 cm equal rows and 10+66 cm narrow-wide rows,which were commonly applied in matching harvest machine.Chemical topping increased seed cotton yield,but did not affect cotton fiber quality comparing to traditional manual topping.Under equal row spacing,the WUE in higher density was 62.4%higher than in the lower one.However,under narrow-wide row spacing,the WUE in lower density was 53.3%higher than in higher one(farmers’practice).For machine-harvest cotton in Xinjiang,the optimal row configuration and plant density for chemical topping was narrow-wide rows with 15 plants m-2 or equal rows with 18 plants m-2.Conclusion The plant density recommended in narrow-wide rows was less than farmers’practice and the density in equal rows was moderate with local practice.Our results provide new knowledge on optimizing agronomic managements of machine-harvested cotton for both high yield and water efficient. 展开更多
关键词 Yield components Fiber quality TRANSPIratioN Water use efficiency Heat ratio method(HRM)
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ESTIMATION OF BLENDING RATIO OF TWO-COMPONENT FIBER BUNDLE FROM BUNDLE LOAD-ELONGATION CURVE
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作者 严灏景 王国强 《Journal of China Textile University(English Edition)》 EI CAS 1989年第1期1-9,共9页
In this paper, two methods were developed to assess the blending ratio of two-componentfiber bundles. They were the peak-height method and the slope method. The relationship be-tween blending ratio and testing data wa... In this paper, two methods were developed to assess the blending ratio of two-componentfiber bundles. They were the peak-height method and the slope method. The relationship be-tween blending ratio and testing data was analysed, and the regression curves were obtained bystepwise regression method. It was pointed out that the testing errors of both methods were lessthan two percent. The validities of both methods were verified by experiments, All calculationsof both methods were completed by computer. The blending ratio was ascertained from the test-ing data of bundle fiber strength tester which was made by the authors themselves. 展开更多
关键词 TWO-componENT fiber BUNDLE tensile properties BLENDING ratio pcak-height METHOD slope METHOD regression CURVE
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Vertical-to-horizontal response spectral ratio for offshore ground motions:Analysis and simplified design equation 被引量:12
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作者 陈宝魁 王东升 +2 位作者 李宏男 孙治国 李超 《Journal of Central South University》 SCIE EI CAS CSCD 2017年第1期203-216,共14页
In order to study the differences in vertical component between onshore and offshore motions,the vertical-to-horizontal peak ground acceleration ratio(V/H PGA ratio) and vertical-to-horizontal response spectral ratio(... In order to study the differences in vertical component between onshore and offshore motions,the vertical-to-horizontal peak ground acceleration ratio(V/H PGA ratio) and vertical-to-horizontal response spectral ratio(V/H) were investigated using the ground motion recordings from the K-NET network and the seafloor earthquake measuring system(SEMS).The results indicate that the vertical component of offshore motions is lower than that of onshore motions.The V/H PGA ratio of acceleration time histories at offshore stations is about 50%of the ratio at onshore stations.The V/H for offshore ground motions is lower than that for onshore motions,especially for periods less than 0.8 s.Furthermore,based on the results in statistical analysis for offshore recordings in the K-NET,the simplified V/H design equations for offshore motions in minor and moderate earthquakes are proposed for seismic analysis of offshore structures. 展开更多
关键词 offshore ground motion vertical component simplified design equation vertical-to-horizontal response spectral ratio (V/H) vertical-to-horizontal peak ground acceleration ratio (V/H PGA ratio K-NET network seafloor earthquake measuring system (SEMS)
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Identification and analysis of serum samples by surface-enhanced Raman spectroscopy combined with characteristic ratio method and PCA for gastric cancer detection 被引量:2
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作者 Liu Guo Yuanpeng Li +5 位作者 Furong Huang Jia Dong Fucui Li Xinhao Yang Siqi Zhu Maoxun Yang 《Journal of Innovative Optical Health Sciences》 SCIE EI CAS 2019年第2期13-23,共11页
This study aimed to explore the application of surface-enhanced Raman scattering(SERS)in the rapid diagnosis of gastric cancer.The SERS spectra of 68 serum samples from gastric cancer patients and healthy volunteers w... This study aimed to explore the application of surface-enhanced Raman scattering(SERS)in the rapid diagnosis of gastric cancer.The SERS spectra of 68 serum samples from gastric cancer patients and healthy volunteers were acquired.The characteristic ratio method(CRM)and principal component analysis(PCA)were used to differentiate gastric cancer serum from normal serum.Compared with healthy volunteers,the serum SERS intensity of gastric cancer patients was relatively high at 722 cm^(-1),while it was relatively low at 588,644,861,1008,1235,1397,1445 and 1586 cm^(-1).These results indicated that the relative content of nucleic acids in the serum of gastric cancer patients rises while the relative content of amino acids and carbohydrates decreases.In PCA,the sensitivity and specificity of discriminating gastric cancer were 94.1%and 94.1%,respectively,with the accuracy of 94.1%.Based on the intensity ratios of four characteristic peaks at 722,861,1008 and 1397 cm^(-1),CRM presented the diagnostic sensitivity and specificity of 100%and 97.4%,respectively,and the accuracy of 98.5%.Therefore,the three peak intensity ratios of I_(722)/I_(861),I_(722)/I_(1008)and I_(722)/I_(1397)can be considered as biologicalfingerprint information for gastric cancer diagnosis and can rapidly and directly reflect the physiological and pathological changes associated with gastric cancer development.This study provides an important basis and standards for the early diagnosis of gastric cancer. 展开更多
关键词 Surface-enhanced Raman spectroscopy SERUM gastric cancer characteristic ratio method principal components analysis
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Application of Different Image Processing Techniques on Aster and ETM+ Images for Exploration of Hydrothermal Alteration Associated with Copper Mineralizations Mapping Kehdolan Area (Eastern Azarbaijan Province-Iran) 被引量:2
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作者 Golchin Hajibapir Mohammad Lotfi +1 位作者 Afshar Zia Zarifi Nima Nezafati 《Open Journal of Geology》 2014年第11期582-597,共16页
The Kehdolan area is located at 20 kilometers to the?south-east of Dozdozan Town (Eastern Azarbaijan Province). According to structural geology, volconic rocks are situated in Alborz-Azarbyjan zone, and faults?are?obs... The Kehdolan area is located at 20 kilometers to the?south-east of Dozdozan Town (Eastern Azarbaijan Province). According to structural geology, volconic rocks are situated in Alborz-Azarbyjan zone, and faults?are?observed?in?the?same direction to this system with SE-NW trend. The results show that kaolinite alteration trend with Argilic and propylitic veins?is the?same direction with SW-NE faults in this area. Therefore, these faults with these trends can be considered as the mineralization control for determination of the alterations. Different image processing techniques,?such as false color composite?(FCC), band ratios, color ratio composite?(CRC), principal component?analysis?(PCA), Crosta technique, supervised spectral angle mapping?(SAM), are used for?identification of the alteration zones associated with copper mineralization. In this project ASTER?data are process and spectral analysis to fit for recognizing intensity and kind of argillic, propylitic,?philic, and ETM+ data?which?are process and to fit for iron oxide and relation to metal mineralization of the area. For recognizing different alterations of the study area, some chemical and mineralogical analysis data from the samples showed that ASTER data and ETM+ data were?capable of hydrothermal alteration mapping with copper mineralization.?Copper mineralization in the region is in agreement with argillic alteration. SW-NE trending faults controlled the mineralization process. 展开更多
关键词 Kehdolan Area False COLOR COMPOSITE Band ratios COLOR ratio COMPOSITE Principal component Analysis Crosta Technique Supervised Spectral Angle MAPPING ASTER DATA ETM+ DATA Alteration
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Analysis of York Pigs Feeding Behavior Using Stepwise Regression and Principal Component Regression 被引量:1
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作者 Xuelin FU Yajing CHEN +2 位作者 Manting WU Junyong HU Wanghong LIU 《Agricultural Biotechnology》 CAS 2021年第2期78-83,共6页
A statistical analysis was conducted on the feeding behavior of 106 York breeding pigs.Pearson correlation analysis,principal component correlation analysis and multiple stepwise regression equation methods were appli... A statistical analysis was conducted on the feeding behavior of 106 York breeding pigs.Pearson correlation analysis,principal component correlation analysis and multiple stepwise regression equation methods were applied to establish regression equations of the York breeding pigs total feed intake per time and average feed intake per time with corrected fat thickness,feed conversion rate,and corrected daily gain.The results showed that:①there were three peak feed intake periods for the pigs,and the correlation coefficient between the feed intake and the corrected fat thickness of the pigs in the 24 h period was positive or negative,that is,increasing the number of feeding times and the feed intake was not necessarily conducive to the fat thickness accumulation,but the breeding goal of fat thickness could be achieved by controlling the feeding times and feed intake;②the average feed intake of pigs in the 60-90 kg body weight stage was 30%-50%higher than that of the 30-60 kg body weight stage,but the number of feeding times decreased,the peak feeding time was more concentrated,and the feeding duration per time was 3.0 min longer,indicating that as the weight of pigs increased,the feed intake increased significantly;and③the stepwise regression equations and the principal component equations showed that the feeding behavior of York pigs in the 30-90 kg growth stage was not only affected by the feeding time within 24 h,but also by environmental factors such as temperature and humidity.The feeding behavior of York pigs is a complex process of interaction between environmental factors and animal factors. 展开更多
关键词 Feed intake Corrected daily weight gain Feed conversion ratio Corrected fat thickness Stepwise regression Principal component regression
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A NEW METHOD OF COMPUTING MULTI-COMPONENT E-pH DIAGRAMS
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作者 Zhang Chuanfu Liu Haixia Zeng Dewen Li Changjun (Department of Nonferrous Metallurgy, Central South University of Technology, Changsha 410083, China) 《Journal of Central South University》 SCIE EI CAS 1999年第1期24-28,共5页
Aqueous E pH Diagram is an essential tool for analyzing hydrometallurgical and corrosion processes. Due to the requirements for environmental protection and energy saving in recent years, waste water processing a... Aqueous E pH Diagram is an essential tool for analyzing hydrometallurgical and corrosion processes. Due to the requirements for environmental protection and energy saving in recent years, waste water processing and hydrometallurgical process of concentrate have been greatly developed. The construction of E pH diagrams has turned to multi component systems. However, there are some limits in plotting such diagrams. There is only one diagram for one multi component system, which can not reflect the truth of the aqueous reaction. In the paper, a new computation method is proposed to construct E pH diagrams. Component activity term is used to determine the boundary of stable areas. For the multi component systems, different atom ratios of elements have been taken into account. M S H 2O system is chosen to study since it is of importance in metallurgical solution. Compared with conventional methods, the algorithm is simple and conforms to real conditions. 展开更多
关键词 computation algorithm of E PH DIAGRAMS component activity term M H 2O SYSTEM M S H 2O SYSTEM atom ratios
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Evaluation of Third-Order Method for the Tests of Variance Component in Linear Mixed Models
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作者 Yanyan Wu Augustine Wong +1 位作者 Georges Monette Laurent Briollais 《Open Journal of Statistics》 2015年第4期233-244,共12页
Mixed models provide a wide range of applications including hierarchical modeling and longitudinal studies. The tests of variance component in mixed models have long been a methodological challenge because of its boun... Mixed models provide a wide range of applications including hierarchical modeling and longitudinal studies. The tests of variance component in mixed models have long been a methodological challenge because of its boundary conditions. It is well documented in literature that the traditional first-order methods: likelihood ratio statistic, Wald statistic and score statistic, provide an excessively conservative approximation to the null distribution. However, the magnitude of the conservativeness has not been thoroughly explored. In this paper, we propose a likelihood-based third-order method to the mixed models for testing the null hypothesis of zero and non-zero variance component. The proposed method dramatically improved the accuracy of the tests. Extensive simulations were carried out to demonstrate the accuracy of the proposed method in comparison with the standard first-order methods. The results show the conservativeness of the first order methods and the accuracy of the proposed method in approximating the p-values and confidence intervals even when the sample size is small. 展开更多
关键词 FAMILY Data GENETIC VARIANT LIKELIHOOD ratio Test RANDOM Effects THIRD-ORDER Method Variance component
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A blind source separation algorithm based on negentropy and signal noise ratio
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作者 万俊 《Journal of Chongqing University》 CAS 2012年第3期134-140,共7页
A novel blind source separation (BSS) algorithm based on the combination of negentropy and signal noise ratio (SNR) is presented to solve the deficiency of the traditional independent component analysis (ICA) al... A novel blind source separation (BSS) algorithm based on the combination of negentropy and signal noise ratio (SNR) is presented to solve the deficiency of the traditional independent component analysis (ICA) algorithm after the introduction of the principle and algorithm of ICA. The main formulas in the novel algorithm are elaborated and the idiographic steps of the algorithm are given. Then the computer simulation is used to test the performance of this algorithm. Both the traditional FastlCA algorithm and the novel ICA algorithm are applied to separate mixed signal data. Experiment results show the novel method has a better performance in separating signals than the traditional FastlCA algorithm based on negentropy. The novel algorithm could estimate the source signals from the mixed signals more precisely. 展开更多
关键词 blind source separation independent component analysis NEGENTROPY signal noise ratio
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Soft sensor for ratio of soda to aluminate based on PCA-RBF multiple network
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作者 桂卫华 李勇刚 王雅琳 《Journal of Central South University of Technology》 2005年第1期88-92,共5页
Based on principal component analysis, a multiple neural network was proposed. The principal component analysis was firstly used to reorganize the input variables and eliminate the correlativity. Then the reorganized ... Based on principal component analysis, a multiple neural network was proposed. The principal component analysis was firstly used to reorganize the input variables and eliminate the correlativity. Then the reorganized variables were divided into 2 groups according to the original information and 2 corresponding neural networks were established. A radial basis function network was used to depict the relationship between the output variables and the first group input variables which contain main original information. An other single-layer neural network model was used to compensate the error between the output of radial basis function network and the actual output variables. At last, The multiple network was used as soft sensor for the ratio of soda to aluminate in the process of high-pressure digestion of alumina. Simulation of industry application data shows that the prediction error of the model is less than 3%, and the model has good generalization ability. 展开更多
关键词 principal component analysis multiple neural network soft sensor ratio of soda to aluminate (generalization ability)
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Speech Separation Methodology for Hearing Aid
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作者 Joseph Sathiadhas Esra Y.Sukhi 《Computer Systems Science & Engineering》 SCIE EI 2023年第2期1659-1678,共20页
In the design of hearing aids(HA),the real-time speech-enhancement is done.The digital hearing aids should provide high signal-to-noise ratio,gain improvement and should eliminate feedback.In generic hearing aids the ... In the design of hearing aids(HA),the real-time speech-enhancement is done.The digital hearing aids should provide high signal-to-noise ratio,gain improvement and should eliminate feedback.In generic hearing aids the perfor-mance towards different frequencies varies and non uniform.Existing noise can-cellation and speech separation methods drops the voice magnitude under the noise environment.The performance of the HA for frequency response is non uni-form.Existing noise suppression methods reduce the required signal strength also.So,the performance of uniform sub band analysis is poor when hearing aid is con-cern.In this paper,a speech separation method using Non-negative Matrix Fac-torization(NMF)algorithm is proposed for wavelet decomposition.The Proposed non-uniformfilter-bank was validated by parameters like band power,Signal-to-noise ratio(SNR),Mean Square Error(MSE),Signal to Noise and Dis-tortion Ratio(SINAD),Spurious-free dynamic range(SFDR),error and time.The speech recordings before and after separation was evaluated for quality using objective speech quality measures International Telecommunication Union-Telecommunication standard ITU-T P.862. 展开更多
关键词 Speech separation waveletfilter independent component analysis(ICA) non-negative matrix factorization(NMF) fejer-korovkin(FK) signal-to-noise ratio(SNR)
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基于FAERS数据库对塞来昔布不良事件信号的分析 被引量:1
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作者 王珊 谢波 +1 位作者 刘慧敏 李志浩 《中国药物警戒》 2024年第2期190-194,198,共6页
目的基于美国食品药品监督管理局(FDA)不良事件报告系统(FAERS)数据库,挖掘塞来昔布的不良事件(ADE)信号,为临床安全用药提供参考。方法采用报告比值比法、综合标准法和信息成分法挖掘FAERS数据库2004年第1季度至2022年第4季度的报告数... 目的基于美国食品药品监督管理局(FDA)不良事件报告系统(FAERS)数据库,挖掘塞来昔布的不良事件(ADE)信号,为临床安全用药提供参考。方法采用报告比值比法、综合标准法和信息成分法挖掘FAERS数据库2004年第1季度至2022年第4季度的报告数据。结果ADE报告人主要为45岁以上人群,以女性居多,上报国家主要是美国。获得塞来昔布ADE报告37020例,涉及ADE 4068种,挖掘ADE信号406个,经筛选后得到有效信号285个,累及23个系统-器官(SOC)。根据信号强度,排名前5位的信号分别为:食管纤维化、与性活动有关的原发性头痛、脑血管疾病、胃肠道腺癌、心血管障碍。说明书未载明的ADE信号主要有:视网膜静脉血栓形成、失明、健忘、过敏性休克等。结论所得ADE信号基本与说明书一致;信号提示塞来昔布ADE主要集中在心脏疾病、神经系统疾病、免疫系统疾病、胃肠道疾病等;说明书黑框警告心血管血栓事件,胃肠道出血、溃疡和穿孔均有相关ADE信号检出。在使用该药时,除注意患者心脑血管、胃肠道不适症状以外,还应关注患者视网膜病变,并做好相关监护,以保证临床用药的安全。 展开更多
关键词 塞来昔布 FAERS 不良事件 信号挖掘 报告比值比法 综合标准法 信息成分法
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有无脉冲近断层地震转动分量对不同高宽比结构动力响应影响
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作者 韩淼 张晨阳 +2 位作者 杜红凯 刘永波 杨杰川 《工程抗震与加固改造》 北大核心 2024年第5期90-97,共8页
建立3个不同高宽比的钢框架结构模型,选取有、无速度脉冲近断层地震波各5条,利用频域法合成地震动摇摆分量和扭转分量,考虑地震动平动、平动耦合摇摆、平动耦合扭转3种工况输入,对结构地震响应分析。结果表明:(1)相比地震动平动分量单... 建立3个不同高宽比的钢框架结构模型,选取有、无速度脉冲近断层地震波各5条,利用频域法合成地震动摇摆分量和扭转分量,考虑地震动平动、平动耦合摇摆、平动耦合扭转3种工况输入,对结构地震响应分析。结果表明:(1)相比地震动平动分量单独作用,平动耦合摇摆、平动耦合扭转均会使结构响应增大;有脉冲地震动作用下的增幅高于无脉冲地震动;(2)平动耦合扭转分量对于结构角柱响应的影响最大,边柱次之,中柱较小;(3)随结构高宽比增加,平动分量耦合摇摆分量的中柱响应增幅大于平动分量耦合扭转分量。 展开更多
关键词 摇摆分量 扭转分量 速度脉冲 高宽比
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1432例老年住院皮肤病患者的临床分析
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作者 张亚丽 曹娟梅 +4 位作者 王雪 李君 梁粟 马小丫 贾雪松 《新疆医学》 2024年第7期762-765,785,共5页
目的分析皮肤科老年住院患者中皮肤病的患病情况及其病种的构成。方法回顾性分析石河子大学第一附属医院皮肤科(以下简称作者所在单位)2019年5月1日至2024年3月31日期间老年住院患者(年龄大于或等于60岁)病例资料,将疾病的分布与年龄在4... 目的分析皮肤科老年住院患者中皮肤病的患病情况及其病种的构成。方法回顾性分析石河子大学第一附属医院皮肤科(以下简称作者所在单位)2019年5月1日至2024年3月31日期间老年住院患者(年龄大于或等于60岁)病例资料,将疾病的分布与年龄在45~59岁的老年前期组进行比较。结果1432例老年住院皮肤病患者占总住院人数的44.05%,男女比例为1.28:1。导致老年人住院最常见的皮肤病是带状疱疹(36.31%),其次是湿疹(23.04%)、银屑病(6.35%)、非特殊性皮炎(5.03%)、特应性皮炎(4.68%)、类天疱疮(3.91%)。和老年前期组相比,在老年患者中发病率明显增加的皮肤病是类天疱疮(8.60倍)、特应性皮炎(1.81倍)、带状疱疹(1.73倍)、湿疹(1.68倍)。另外,上述皮肤病在老年病人及老年前期组(45~59岁)病人间的患病率差异均具有统计学意义(P<0.05)。在老年患者中,湿疹、银屑病、特应性皮炎、类天疱疮好发于男性,而带状疱疹和荨麻疹多见于女性。结论皮肤病在老年人中比较常见,其病种的构成与国内之前的报道部分相近。年龄和性别的不同导致疾病的发病率也不同。 展开更多
关键词 皮肤病 老年人 住院 构成比
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