BACKGROUND Patients with Crohn’s disease(CD)are at risk of developing complications such as perianal fistulas.Patients with Crohn’s perianal fistulas(CPF)are affected by fecal incontinence(FI),bleeding,pain,swelling...BACKGROUND Patients with Crohn’s disease(CD)are at risk of developing complications such as perianal fistulas.Patients with Crohn’s perianal fistulas(CPF)are affected by fecal incontinence(FI),bleeding,pain,swelling,and purulent perianal discharge,and METHODS This cross-sectional observational study was conducted in patients with CD aged 21-90 years via a web-enabled questionnaire in seven countries(April-August 2021).Patients were recruited into three cohorts:Cohort 1 included patients without perianal fistulas;cohort 2 included patients with perianal fistulas without fistula-related surgery;and cohort 3 included patients with perianal fistulas and fistula-related surgery.Validated patient-reported outcome measures were used to assess quality of life.Drivers of treatment preferences were measured using a discrete choice experiment(DCE).RESULTS In total,929 patients were recruited(cohort 1,n=620;cohort 2,n=174;cohort 3,n=135).Short Inflammatory Bowel Disease Questionnaire scores were worse for patients with CPF(cohorts 2 and 3)than for those with CD without CPF(cohort 1):Mean score 3.8 and 3.7 vs 4.1,respectively,(P<0.001).Similarly,mean Revised FI and FI Quality of Life scores were worse for patients with CPF than for those with CD without CPF.Quality of Life with Anal Fistula scores were similar in patients with CPF with or without CPF-related surgery(cohorts 2 and 3):Mean score 41 and 42,respectively.In the DCE,postoperative discomfort and fistula healing rate were the most important treatment attributes influencing treatment choice:Mean relative importance 35.7 and 24.7,respectively.CONCLUSION The burden of illness in CD is significantly higher for patients with CPF and patients rate lower postoperative discomfort and higher healing rates as the most desirable treatment attributes.展开更多
Game theory is extensively used to study strategy-making and actions of play- ers. The authors proposed an analysis method for study the evolutionary outcome and behaviors of players with preference in iterated priso...Game theory is extensively used to study strategy-making and actions of play- ers. The authors proposed an analysis method for study the evolutionary outcome and behaviors of players with preference in iterated prisoner＇s dilemma. In this article, a preference parameter k was introduced in the payoff matrix, wherein the value of k denotes the player＇s degree of egoism and altruism （preference）. Then, a game-theoretic dynamical model was formulated using Birth-and-Death process. The authors studied how preference influences the evolutionary equilibrium and behaviors of players. The authors get the general results： egoism leads to defection, and altruism can make players build trust and maintain cooperation, and so, the hope of the Pareto optimal solution. In the end, the simulation experiments proved the efficiency of the method.展开更多
BACKGROUND Inflammatory bowel disease(IBD)patients’expectations of treatment outcomes may differ by ethnicity.AIM To investigate treatment preferences of Jewish and Arabs patients.METHODS This prospective survey rank...BACKGROUND Inflammatory bowel disease(IBD)patients’expectations of treatment outcomes may differ by ethnicity.AIM To investigate treatment preferences of Jewish and Arabs patients.METHODS This prospective survey ranked outcomes treatment preferences among Arab IBD patients,based on the 10 IBD-disk items compared to historical data of Jews.An anonymous questionnaire in either Arabic or Hebrew was distributed among IBD patients.Patients were required to rank 10 statements describing different aspects of IBD according to their importance to the patients as treatment goals.Answers were compared to the answers of a historical group of Jewish patients.RESULTS IBD-disk items of 121 Arabs were compared to 240 Jewish patients.The Jewish patients included more females,[151(62.9%)vs 52(43.3%);P<0.001],higher education level(P=0.02),more urban residence[188(78.3%)vs 54(45.4%);P<0.001],less unemployment[52(21.7%)vs 41(33.9%);P=0.012],higher income level(P<0.001),and more in a partnership[162(67.8%)vs 55(45.4%);P<0.001].Expectations regarding disease symptoms:abdominal pain,energy,and regular defecation ranked highest for both groups.Arabs gave significantly lower rankings(range 4.29-6.69)than Jewish patients(range 6.25-9.03)regarding all items,except for body image.Compared to Arab women,Jewish women attached higher priority to abdominal pain,energy,education/work,sleep,and joint pain.Multivariable regression analysis revealed that higher patient preferences were associated with Jewish ethnicity(OR 4.77;95%CI 2.36-9.61,P<0.001)and disease activity.The more active the disease,the greater the odds ratio for higher ranking of the questionnaire items(1-2 attacks per year:OR 2.13;95%CI 1.02-4.45,P=0.043;and primarily active disease:OR 5.29;95%CI 2.30-12.18,P<0.001).Factors inversely associated with higher patient preference were male gender(OR 0.5;95%CI 0.271-0.935,P=0.030),UC(OR 0.444;95%CI 0.241-0.819,P=0.009),and above average income level(OR 0.267;95%CI:0.124-0.577,P=0.001).CONCLUSION The highest priority for treatment outcomes was symptom relief.,Patients preferences were impacted by ethnicity,gender,and socio-economic disparity.Understanding patients'priorities may improve communication and enable a personalized approach.展开更多
With stepwise development of Chinese enterprise,management problem is increasingly prominent,especially human resource management issues. Facing international environment of entering into World Trade Organization,the ...With stepwise development of Chinese enterprise,management problem is increasingly prominent,especially human resource management issues. Facing international environment of entering into World Trade Organization,the country accelerates construction pace of human resource management subject in colleges and universities,which provides professional channel for management efficiency and market competition ability of Chinese enterprise,but it is still far from practice. In this paper,the concept,origin and inhibition factors of ingroup preference are elaborated. Based on the visual angle of ingroup preference,started from four dimensions( enterprise incentive system,talent management idea,psychological contract and employee communication consciousness),main problems existing in employee relationship management of modern enterprise are explored. It is specially emphasized that manager often holds the blame in front of dealing with the crisis after contradiction,which is " fatal point" neglected in employee relationship management of modern enterprise. To improve its core competitive power,enterprise must value harmonious relationship with employees.展开更多
Among the sundry studies in China on John Donne's The Flea,there has been none done from the perspective of Reader-Oriented Theory to probe into the readers' roles in the construction of meaning.The present ar...Among the sundry studies in China on John Donne's The Flea,there has been none done from the perspective of Reader-Oriented Theory to probe into the readers' roles in the construction of meaning.The present article under Wolfgang Iser's theories,in a further pursuit of the expansion of the gestalt of such studies on the poem,aims at exploring the readers' active roles in complementing,completing and recreating the textual meaning,and differentiating the implied reader and the actual reader through the poem as well as attempting to fulfill the construction of the reading cognitive model through the interpretation of the conceit the flea.展开更多
The Catcher in the Rye has been popular with readers since its publication,and critics at home and abroad have also conducted a lot of research on it.But they mainly proceed from the author and the text to evaluate an...The Catcher in the Rye has been popular with readers since its publication,and critics at home and abroad have also conducted a lot of research on it.But they mainly proceed from the author and the text to evaluate and analyze,ignoring the readers who are essential participants in text interpretation in the eyes of reader-response critics.In order to make up for this shortcoming,this article will take Iser’s reader-response criticism as a research perspective,starting from the three aspects of implied reader,response-inviting structure,and gaps to explore the interaction between the text of The Catcher in the Rye and the readers during the reading process.This research is expected to provide a new interpretation of this novel and provide reference for future research in related fields.展开更多
T. S. Eliot is always considered as the pioneering father and founder of the New Criticism. This paper compares the similarities and differences of T. S. Eliot's relevant theories with those of the New Criticism f...T. S. Eliot is always considered as the pioneering father and founder of the New Criticism. This paper compares the similarities and differences of T. S. Eliot's relevant theories with those of the New Criticism from two aspects: their viewpoints of the literary works and those of the reader. It concludes that though they share the same belief in the importance of the literary works, the New Criticism is good at the subtle analysis of one text and another. However, Eliot recognizes the reader's function in the appreciation of the works which New Criticism totally objects to, and their responses should be properly considered in the criticism of the works.展开更多
Many of our readers have been reading our magazine for years. But very few of them have been to Tibet. The landscape is number one in the world. It is highlighted by the Tibetan culture is unique. However, this is wha...Many of our readers have been reading our magazine for years. But very few of them have been to Tibet. The landscape is number one in the world. It is highlighted by the Tibetan culture is unique. However, this is what is described in written language. What is Tibet really like? Is Tibet a region just as described by China’s Tibet?展开更多
Many of our readers have been reading our magazine for years. But very few of them have been to Tibet.The landscape is number one in the world. It is highlighted by the Tibetan culture is unique.However, this is what ...Many of our readers have been reading our magazine for years. But very few of them have been to Tibet.The landscape is number one in the world. It is highlighted by the Tibetan culture is unique.However, this is what is described in written language.What is Tibet really like? Is Tibet a region just as described by China’s Tibet?We sincerely invite our readers and friends to visit in order to see Tibet with their own eyes and talk to our editors.展开更多
Disturbances caused by livestock grazing are considered as a key attributable factor for the habitat loss of red panda. The present study was carried out in Eastern Nepal mainly focusing on the habitat preferences of ...Disturbances caused by livestock grazing are considered as a key attributable factor for the habitat loss of red panda. The present study was carried out in Eastern Nepal mainly focusing on the habitat preferences of red panda and impacts of livestock grazing on it. In total, 15 linear transects were delineated at an elevation interval of 100 m assessing indirect signs of red panda and livestock. Habitat preferences of red panda, vegetation abundance, coverage percentage of vegetation layers (canopy and shrub layer) and distance to water source were recorded using randomly plotted 58 quadrats of 10 m × 10 m. Questionnaire survey and Key Informant Interviews were carried out to evaluate the perception of local community on conservation threats and importance of red panda conservation. Jaccard’s similarity index was used to determine the spatial habitat overlap of livestock and red panda. Litsea elongata, Lithocarpus pachyphylla and Rhododendron falconeri were the most common species in the study area. Grazing signs were observed from 51% of red panda habitats in the study area. Livestock herding has induced negative impacts on the habitat of red panda inside the community forests. The study findings will extend the existing body of knowledge regarding the status of red panda in Eastern Himalayas. In addition, this research will help in the formulation of effective legal and strategic framework of sustainable grazing management.展开更多
文摘BACKGROUND Patients with Crohn’s disease(CD)are at risk of developing complications such as perianal fistulas.Patients with Crohn’s perianal fistulas(CPF)are affected by fecal incontinence(FI),bleeding,pain,swelling,and purulent perianal discharge,and METHODS This cross-sectional observational study was conducted in patients with CD aged 21-90 years via a web-enabled questionnaire in seven countries(April-August 2021).Patients were recruited into three cohorts:Cohort 1 included patients without perianal fistulas;cohort 2 included patients with perianal fistulas without fistula-related surgery;and cohort 3 included patients with perianal fistulas and fistula-related surgery.Validated patient-reported outcome measures were used to assess quality of life.Drivers of treatment preferences were measured using a discrete choice experiment(DCE).RESULTS In total,929 patients were recruited(cohort 1,n=620;cohort 2,n=174;cohort 3,n=135).Short Inflammatory Bowel Disease Questionnaire scores were worse for patients with CPF(cohorts 2 and 3)than for those with CD without CPF(cohort 1):Mean score 3.8 and 3.7 vs 4.1,respectively,(P<0.001).Similarly,mean Revised FI and FI Quality of Life scores were worse for patients with CPF than for those with CD without CPF.Quality of Life with Anal Fistula scores were similar in patients with CPF with or without CPF-related surgery(cohorts 2 and 3):Mean score 41 and 42,respectively.In the DCE,postoperative discomfort and fistula healing rate were the most important treatment attributes influencing treatment choice:Mean relative importance 35.7 and 24.7,respectively.CONCLUSION The burden of illness in CD is significantly higher for patients with CPF and patients rate lower postoperative discomfort and higher healing rates as the most desirable treatment attributes.
基金supported by National Natural Science Foundation of China(60574071)
文摘Game theory is extensively used to study strategy-making and actions of play- ers. The authors proposed an analysis method for study the evolutionary outcome and behaviors of players with preference in iterated prisoner＇s dilemma. In this article, a preference parameter k was introduced in the payoff matrix, wherein the value of k denotes the player＇s degree of egoism and altruism （preference）. Then, a game-theoretic dynamical model was formulated using Birth-and-Death process. The authors studied how preference influences the evolutionary equilibrium and behaviors of players. The authors get the general results： egoism leads to defection, and altruism can make players build trust and maintain cooperation, and so, the hope of the Pareto optimal solution. In the end, the simulation experiments proved the efficiency of the method.
文摘BACKGROUND Inflammatory bowel disease(IBD)patients’expectations of treatment outcomes may differ by ethnicity.AIM To investigate treatment preferences of Jewish and Arabs patients.METHODS This prospective survey ranked outcomes treatment preferences among Arab IBD patients,based on the 10 IBD-disk items compared to historical data of Jews.An anonymous questionnaire in either Arabic or Hebrew was distributed among IBD patients.Patients were required to rank 10 statements describing different aspects of IBD according to their importance to the patients as treatment goals.Answers were compared to the answers of a historical group of Jewish patients.RESULTS IBD-disk items of 121 Arabs were compared to 240 Jewish patients.The Jewish patients included more females,[151(62.9%)vs 52(43.3%);P<0.001],higher education level(P=0.02),more urban residence[188(78.3%)vs 54(45.4%);P<0.001],less unemployment[52(21.7%)vs 41(33.9%);P=0.012],higher income level(P<0.001),and more in a partnership[162(67.8%)vs 55(45.4%);P<0.001].Expectations regarding disease symptoms:abdominal pain,energy,and regular defecation ranked highest for both groups.Arabs gave significantly lower rankings(range 4.29-6.69)than Jewish patients(range 6.25-9.03)regarding all items,except for body image.Compared to Arab women,Jewish women attached higher priority to abdominal pain,energy,education/work,sleep,and joint pain.Multivariable regression analysis revealed that higher patient preferences were associated with Jewish ethnicity(OR 4.77;95%CI 2.36-9.61,P<0.001)and disease activity.The more active the disease,the greater the odds ratio for higher ranking of the questionnaire items(1-2 attacks per year:OR 2.13;95%CI 1.02-4.45,P=0.043;and primarily active disease:OR 5.29;95%CI 2.30-12.18,P<0.001).Factors inversely associated with higher patient preference were male gender(OR 0.5;95%CI 0.271-0.935,P=0.030),UC(OR 0.444;95%CI 0.241-0.819,P=0.009),and above average income level(OR 0.267;95%CI:0.124-0.577,P=0.001).CONCLUSION The highest priority for treatment outcomes was symptom relief.,Patients preferences were impacted by ethnicity,gender,and socio-economic disparity.Understanding patients'priorities may improve communication and enable a personalized approach.
文摘With stepwise development of Chinese enterprise,management problem is increasingly prominent,especially human resource management issues. Facing international environment of entering into World Trade Organization,the country accelerates construction pace of human resource management subject in colleges and universities,which provides professional channel for management efficiency and market competition ability of Chinese enterprise,but it is still far from practice. In this paper,the concept,origin and inhibition factors of ingroup preference are elaborated. Based on the visual angle of ingroup preference,started from four dimensions( enterprise incentive system,talent management idea,psychological contract and employee communication consciousness),main problems existing in employee relationship management of modern enterprise are explored. It is specially emphasized that manager often holds the blame in front of dealing with the crisis after contradiction,which is " fatal point" neglected in employee relationship management of modern enterprise. To improve its core competitive power,enterprise must value harmonious relationship with employees.
文摘Among the sundry studies in China on John Donne's The Flea,there has been none done from the perspective of Reader-Oriented Theory to probe into the readers' roles in the construction of meaning.The present article under Wolfgang Iser's theories,in a further pursuit of the expansion of the gestalt of such studies on the poem,aims at exploring the readers' active roles in complementing,completing and recreating the textual meaning,and differentiating the implied reader and the actual reader through the poem as well as attempting to fulfill the construction of the reading cognitive model through the interpretation of the conceit the flea.
文摘The Catcher in the Rye has been popular with readers since its publication,and critics at home and abroad have also conducted a lot of research on it.But they mainly proceed from the author and the text to evaluate and analyze,ignoring the readers who are essential participants in text interpretation in the eyes of reader-response critics.In order to make up for this shortcoming,this article will take Iser’s reader-response criticism as a research perspective,starting from the three aspects of implied reader,response-inviting structure,and gaps to explore the interaction between the text of The Catcher in the Rye and the readers during the reading process.This research is expected to provide a new interpretation of this novel and provide reference for future research in related fields.
文摘T. S. Eliot is always considered as the pioneering father and founder of the New Criticism. This paper compares the similarities and differences of T. S. Eliot's relevant theories with those of the New Criticism from two aspects: their viewpoints of the literary works and those of the reader. It concludes that though they share the same belief in the importance of the literary works, the New Criticism is good at the subtle analysis of one text and another. However, Eliot recognizes the reader's function in the appreciation of the works which New Criticism totally objects to, and their responses should be properly considered in the criticism of the works.
文摘Many of our readers have been reading our magazine for years. But very few of them have been to Tibet. The landscape is number one in the world. It is highlighted by the Tibetan culture is unique. However, this is what is described in written language. What is Tibet really like? Is Tibet a region just as described by China’s Tibet?
文摘Many of our readers have been reading our magazine for years. But very few of them have been to Tibet.The landscape is number one in the world. It is highlighted by the Tibetan culture is unique.However, this is what is described in written language.What is Tibet really like? Is Tibet a region just as described by China’s Tibet?We sincerely invite our readers and friends to visit in order to see Tibet with their own eyes and talk to our editors.
文摘Disturbances caused by livestock grazing are considered as a key attributable factor for the habitat loss of red panda. The present study was carried out in Eastern Nepal mainly focusing on the habitat preferences of red panda and impacts of livestock grazing on it. In total, 15 linear transects were delineated at an elevation interval of 100 m assessing indirect signs of red panda and livestock. Habitat preferences of red panda, vegetation abundance, coverage percentage of vegetation layers (canopy and shrub layer) and distance to water source were recorded using randomly plotted 58 quadrats of 10 m × 10 m. Questionnaire survey and Key Informant Interviews were carried out to evaluate the perception of local community on conservation threats and importance of red panda conservation. Jaccard’s similarity index was used to determine the spatial habitat overlap of livestock and red panda. Litsea elongata, Lithocarpus pachyphylla and Rhododendron falconeri were the most common species in the study area. Grazing signs were observed from 51% of red panda habitats in the study area. Livestock herding has induced negative impacts on the habitat of red panda inside the community forests. The study findings will extend the existing body of knowledge regarding the status of red panda in Eastern Himalayas. In addition, this research will help in the formulation of effective legal and strategic framework of sustainable grazing management.
