Rhodamine B-ethylenediamine-beta-cyclodextrins (RhB-beta-CDen) and rhodamine B-beta-cyclodextrins (RhB-beta-CD) form inclusion complexes with many guest molecules, which can be used as nucleic acid probe. In this pape...Rhodamine B-ethylenediamine-beta-cyclodextrins (RhB-beta-CDen) and rhodamine B-beta-cyclodextrins (RhB-beta-CD) form inclusion complexes with many guest molecules, which can be used as nucleic acid probe. In this paper we determined the most stable conformations of RhB-beta-CDen and RhB-beta-CD by molecular mechanics and dynamics simulation. The interaction between RhB-beta-CDen and two guest molecules, 1-borneol and cyclohexanol, have been investigated both theoretically and experimentally. The results show that the interaction between borneol and RhB-beta-CDen is stronger than that between cyclohexanol and RhB-beta-CDen.展开更多
After pointed the unreasonableness of the three basic assumptions contained in HMM, we introduce the theory and the advantage of Stochastic najectory Models (STMs) that possibly resolve these problems caused by HMM as...After pointed the unreasonableness of the three basic assumptions contained in HMM, we introduce the theory and the advantage of Stochastic najectory Models (STMs) that possibly resolve these problems caused by HMM assumptions. In STM, the acoustic observations of an acoustic unit are represented as clusters of trajectories in a parameter space.The trajectories are modelled by mixture of probability density functions of random sequence of states. After analyzing the characteristics of Chinese speech, the acoustic units for continuous Chinese speech recognition based on STM are discussed and phone-like units are suggested. The performance of continuous Chinese speech recognition based on STM is studied on VINICS system. The experimental results prove the efficiency of STM and the consistency of phone-like units.展开更多
文摘Rhodamine B-ethylenediamine-beta-cyclodextrins (RhB-beta-CDen) and rhodamine B-beta-cyclodextrins (RhB-beta-CD) form inclusion complexes with many guest molecules, which can be used as nucleic acid probe. In this paper we determined the most stable conformations of RhB-beta-CDen and RhB-beta-CD by molecular mechanics and dynamics simulation. The interaction between RhB-beta-CDen and two guest molecules, 1-borneol and cyclohexanol, have been investigated both theoretically and experimentally. The results show that the interaction between borneol and RhB-beta-CDen is stronger than that between cyclohexanol and RhB-beta-CDen.
文摘After pointed the unreasonableness of the three basic assumptions contained in HMM, we introduce the theory and the advantage of Stochastic najectory Models (STMs) that possibly resolve these problems caused by HMM assumptions. In STM, the acoustic observations of an acoustic unit are represented as clusters of trajectories in a parameter space.The trajectories are modelled by mixture of probability density functions of random sequence of states. After analyzing the characteristics of Chinese speech, the acoustic units for continuous Chinese speech recognition based on STM are discussed and phone-like units are suggested. The performance of continuous Chinese speech recognition based on STM is studied on VINICS system. The experimental results prove the efficiency of STM and the consistency of phone-like units.
