To extend the service life of the upper checker bricks in the regenerator of glass furnaces with petroleum coke as fuel,the corrosion resistance of magnesia-chrome and alumina-chrome bricks with the similar apparent p...To extend the service life of the upper checker bricks in the regenerator of glass furnaces with petroleum coke as fuel,the corrosion resistance of magnesia-chrome and alumina-chrome bricks with the similar apparent porosity was systematically researched.The results show that the Cr2O3 content and the microstructure present significant effects on the corrosion resistance.The molten corrosion reagent forms silicate and vanadate phases with low melting points between MgO crystals in magnesia-chrome bricks,and the volume strain generated by the melting and solidification process leads to the cracking and spalling of refractories,which intensifies the corrosion process.The encapsulation of alumina particles by alumina-chrome solid solutions in alumina-chrome bricks avoids contact with the low melting point liquid phases and improves the corrosion resistance of refractories.展开更多
In this article, researches on improvement of 1RX regenerator used in cleaning processes of cotton ginning enterprises were carried out. The effect of changing the parameters of the new working body—rubber-plate drum...In this article, researches on improvement of 1RX regenerator used in cleaning processes of cotton ginning enterprises were carried out. The effect of changing the parameters of the new working body—rubber-plate drum and machine inlet on the efficiency of cotton separation was studied in the research, and the maximum level of efficiency of separation was determined. In this paper work, the main factors affecting the efficient operation of the regenerator were identified, their value limits were determined, and research was conducted using the mathematical planning method. As a result, effective operation of the improved 1RX cotton regenerator was observed at the value of the given factors, that is, the separation efficiency was 99.5%, the cleaning efficiency was higher than 88.7%, and the amount of seed cotton in the waste was reduced lower than 2.5%.展开更多
The quantitative investigation of parameters in the renegerator is essential for the optimization of thermoacoustic devices, while the majority of the previous research only considered parameters of the working field,...The quantitative investigation of parameters in the renegerator is essential for the optimization of thermoacoustic devices, while the majority of the previous research only considered parameters of the working field, working gas and the hydraulic radius. Based on the linear thermoacoustic theory, this paper extracts a normalized parameter for low-amplitude conditions, which is called the regenerator operation factor. By extracting the regenerator operation factor and relative hydraulic radius, the influence of frequency on the efficiency can be controlled and offset. It can be found that thermoacoustic devices with different frequencies can perform the same efficiency by adjusting the radius in proportion to the axial length.Finally, this paper synthetically optimizes the dimension of the thermoacoustic regenerator by taking the regenerator operation factor, relative hydraulic radius and acoustic field parameter as variables. Conclusions in this paper are of great significance for explaining the best working conditions of engines and directing the miniaturization and optimal design of thermoacoustic devices.展开更多
The special subject'research on life prediction technology of important in-service pressure vessels' mainly analyzes the failure mechanism of large-sized important and critical in-service pressure vessels unde...The special subject'research on life prediction technology of important in-service pressure vessels' mainly analyzes the failure mechanism of large-sized important and critical in-service pressure vessels under the action of working medium and investigates safety assessment and life prediction technology with a view to enhance the operation reliability of in-service pressure vessels in China. Based on a series of accident investigation and test & measuring research, the cause of cracking of catalytic regenerator is analyzed and the in-line non-destructive examination method and failure prevention measures for the cracking of catalytic regenerator are proposed.展开更多
A new method was proposed to directly measure the effective resistance and distinguish the porous frequency in the regenerator of the microminiature thermoacoustic refrigerator. Measured results were compared with the...A new method was proposed to directly measure the effective resistance and distinguish the porous frequency in the regenerator of the microminiature thermoacoustic refrigerator. Measured results were compared with the flux gain factor and transmission loss of the real system. The results show that the agreement between the range of the porous frequency and frequency of the system is good, the method can be used to predict the porous frequency of the regenerator in production.展开更多
An active thermo-acoustic network model of regenerator which is a key component to accomplish the con-version between thermal-and acoustic power in thermo-acoustic system has been established in this paper. The experi...An active thermo-acoustic network model of regenerator which is a key component to accomplish the con-version between thermal-and acoustic power in thermo-acoustic system has been established in this paper. The experiment was carried out to quantify the network. A method called least square is employed in order to identify the H matrix describing the system. The results obtained here show that the active thermo-acoustic network can reliably depict the characteristics of a thermo-acoustic system.展开更多
An approach for the simulation and optimization of continuous catalyst-regenerative process of reforming is proposed in this paper.Compared to traditional method such as finite difference method,the orthogonal colloca...An approach for the simulation and optimization of continuous catalyst-regenerative process of reforming is proposed in this paper.Compared to traditional method such as finite difference method,the orthogonal collocation method is less time-consuming and more accurate,which can meet the requirement of real-time optimization(RTO).In this paper,the equation-oriented method combined with the orthogonal collocation method and the finite difference method is adopted to build the RTO model for catalytic reforming regenerator.The orthogonal collocation method was adopted to discretize the differential equations and sequential quadratic programming(SQP)algorithm was used to solve the algebraic equations.The rate constants,active energy and reaction order were estimated,with the sum of relative errors between actual value and simulated value serving as optimization objective function.The model can quickly predict the fields of component concentration,temperature and pressure inside the regenerator under different conditions,as well as the real-time optimized conditions for industrial reforming regenerator.展开更多
During long-term use,the clay checker bricks for regenerators of coke ovens on gas side react with the impurities containing Fe and K20,causing foaming,softening and deformation,which is not only related with the impu...During long-term use,the clay checker bricks for regenerators of coke ovens on gas side react with the impurities containing Fe and K20,causing foaming,softening and deformation,which is not only related with the impurity content and properties of the clay checker bricks,but also related with the type and the composition of the dust in the gas.After long term use,the clay checker bricks of coke ovens on air side have relative lower impurities containing Fe and K20.The inferior clay checker bricks,with high impurity content and high porosity,are easy to pulverize and deteriorate due to the oxidationreduction reaction with the iron oxide and the gas.The gas quality shall be concerned for long service life of the coke oven regenerators.展开更多
Regenerator checkerwork for glass melting furnaces should have high resistance against thermal stress and chemical attack,high mechanical stability,high efficiency to recover the heat from waste gas and low tendency f...Regenerator checkerwork for glass melting furnaces should have high resistance against thermal stress and chemical attack,high mechanical stability,high efficiency to recover the heat from waste gas and low tendency for clogging.This article reviews the innovation of the regenerator checkerwork from the past decades.The state of the art for optimised material choice and optimised checker shapes will be reported.展开更多
The catalyst regeneration process running under the partial oxidation mode in traditional fluid catalytic cracking(FCC)units needs a carbon monoxide(CO)boiler to burn the flue gas,resulting in a large volume of CO_(2)...The catalyst regeneration process running under the partial oxidation mode in traditional fluid catalytic cracking(FCC)units needs a carbon monoxide(CO)boiler to burn the flue gas,resulting in a large volume of CO_(2) emissions.In this study,the performance of a set of industrial serial-type FCC regenerators and the changes in flue gas composition were analyzed by establishing a model of the regenerators and the flue gas energy recovery section.Considering the value of utilizing CO,based on the simulation,this paper proposes two schemes for maximizing CO content in the flue gas of regenerators.The two sets of optimal process operating parameters were obtained using a genetic algorithm.Compared with the original process,the CO contents of flue gas in the two optimized processes increased to 6.6%and 12.5%,CO_(2) emissions were reduced by 48.4%and 96.7%,and the costs of CO production were 0.57$/m^(3) and 0.84$/m^(3),respectively.展开更多
In order to provide a novel and more effective alternative to the commonly used relay protection testing device that outputs only the sinusoidal testing signals, the concept of fault waveform regenerator is proposed i...In order to provide a novel and more effective alternative to the commonly used relay protection testing device that outputs only the sinusoidal testing signals, the concept of fault waveform regenerator is proposed in this paper, together with its hardware structure and software flow chart. Fault waveform regenerator mainly depends on its power amplifiers (PAs) to regenerate the fault waveforms recorded by digital fault recorder (DFR). To counteract the PA’s inherent nonlinear distortions, a digital closed-loop modification technique that is different from the predistortion technique is conceived. And the experimental results verify the effectiveness of the fault waveform regenerator based on the digital closed-loop modification technique.展开更多
Regenerators play a vital role in enhancing the overall performance of Stirling engines.Hence,this paper performed an energy and exergy analysis to elucidate the significance of regenerator characteristics concerning ...Regenerators play a vital role in enhancing the overall performance of Stirling engines.Hence,this paper performed an energy and exergy analysis to elucidate the significance of regenerator characteristics concerning system performance,contributing to the optimal regenerator’s design and selection.The relationship between regenerator structure,regenerator exergy destruction,and output power,thermal efficiency,and exergy efficiency for Stirling engines was established by integrating the thermal model of Stirling engines with a mathematical model of regenerators.In contrast to cross-flow and parallel-flow regenerators,a novel concept of inclined-flow regenerators,featuring a matrix surface inclined in the direction of gas flow,was developed to achieve higher and more balanced engine output power and energy utilization efficiency.A comprehensive investigation was conducted into the effects of matrix structure types and regenerator geometries on the performance of both regenerators and engines.The results reveal that,following structural optimization,Stirling engines equipped with the inclined-flow regenerator demonstrate a substantial 16.6%,38.3%,and 37.2%increase in power output,thermal efficiency,and exergy efficiency,respectively,compared to those equipped with cross-flow regenerators.In contrast,when compared to engines fitted with parallel-flow regenerators,they experience a 13.5%reduction in power output but achieve remarkable enhancements of 45.4%and 36.7%in thermal and exergy efficiency,respectively.This study introduces new insights into selecting regenerator structures for enhancing the output performance of Stirling engines.展开更多
The generation and manipulation of optical vortices are of fundamental importance in a variety of promising applications. Here, we develop a nonlinear optical paradigm to implement self-and cross-convolution of optica...The generation and manipulation of optical vortices are of fundamental importance in a variety of promising applications. Here, we develop a nonlinear optical paradigm to implement self-and cross-convolution of optical vortex arrays, demonstrating the features of a vortex copier and regenerator. We use a phase-only spatial light modulator to prepare the 1064 nm invisible fundamental light to carry special optical vortex arrays and use a potassium titanyl phosphate crystal to perform type Ⅱ second-harmonic generation in the Fourier domain to achieve 532 nm visible structured vortices. Based on pure cross-convolution, we succeed in copying arbitrary-order single vortices as well as their superposition states onto a prearranged array of fundamental Gaussian spots. Also, based on the simultaneous effect of self-and cross-convolutions, we can expand the initial vortex lattices to regenerate more vortices carrying various higher topological charges. Our presented method of realizing an optical vortex copier and regenerator could find direct applications in optical manipulation, optical imaging, optical communication, and quantum information processing with structured vortex arrays.展开更多
Inflammatory skin disorders can cause chronic scarring and functional impairments,posing a significant burden on patients and the healthcare system.Conventional therapies,such as corticosteroids and nonsteroidal anti-...Inflammatory skin disorders can cause chronic scarring and functional impairments,posing a significant burden on patients and the healthcare system.Conventional therapies,such as corticosteroids and nonsteroidal anti-inflammatory drugs,are limited in efficacy and associated with adverse effects.Recently,nanozyme(NZ)-based hydrogels have shown great promise in addressing these challenges.NZ-based hydrogels possess unique therapeutic abilities by combining the therapeutic benefits of redox nanomaterials with enzymatic activity and the water-retaining capacity of hydrogels.The multifaceted therapeutic effects of these hydrogels include scavenging reactive oxygen species and other inflammatory mediators modulating immune responses toward a pro-regenerative environment and enhancing regenerative potential by triggering cell migration and differentiation.This review highlights the current state of the art in NZ-engineered hydrogels(NZ@hydrogels)for anti-inflammatory and skin regeneration applications.It also discusses the underlying chemo-mechano-biological mechanisms behind their effectiveness.Additionally,the challenges and future directions in this ground,particularly their clinical translation,are addressed.The insights provided in this review can aid in the design and engineering of novel NZ-based hydrogels,offering new possibilities for targeted and personalized skin-care therapies.展开更多
Graphene-based materials possess significant potential for the treatment of dye wastewater due to their exceptional adsorption properties toward stubborn pollutants.However,their utilization is hindered by high prepar...Graphene-based materials possess significant potential for the treatment of dye wastewater due to their exceptional adsorption properties toward stubborn pollutants.However,their utilization is hindered by high preparation costs,low yields,environmental pollution during synthesis,and challenges in regenerating the adsorbent.This study proposes a novel approach to address these limitations by developing nitrogen-doped three-dimensional(3D)polyvinyl alcohol(PVA)crosslinked graphene sponges(N-PGA)using a cross-linking method with ammonium carbonate.This method offers a relatively mild,environmentally friendly approach.Ammonium carbonate serves as both a reducing and modifying agent,facilitating the formation of the intrinsic structure of N-PGA and acting as a nitrogen source.Meanwhile,PVA is utilized as the cross-linking agent.The results demonstrate that N-PGA exhibits a favorable internal 3D hierarchical porous structure and possesses robust mechanical properties.The measured specific surface area(BET)of N-PGA was as high as406.538 m^(2)·g^(-1),which was favorable for its efficient adsorption of Congo red(CR)dye molecules.At an initial concentration of 50 mg·L^(-1),N-PGA achieved an impressive removal rate of 89.6%and an adsorption capacity of 112 mg·g^(-1)for CR dye.Furthermore,it retained 79%of its initial adsorption capacity after 10 cycles,demonstrating excellent regeneration performance.In summary,the synthesized N-PGA displays remarkable efficacy in the adsorption of CR dye in wastewater,opening up new possibilities for utilizing 3D porous graphene nanomaterials as efficient adsorbents in wastewater treatment.展开更多
On an agrosilvopastoral farm in central Italy where Maremmana cattle graze in Turkey oak forests,we evaluated the impact of different livestock densities on stand structure,tree diversity and natural regeneration in f...On an agrosilvopastoral farm in central Italy where Maremmana cattle graze in Turkey oak forests,we evaluated the impact of different livestock densities on stand structure,tree diversity and natural regeneration in four types of grazed areas based on the grazing regime adopted:calf-grazed,high-intensity-grazed,low-intensity-grazed,ungrazed control.For each area,we set up three permanent circular plots(radius of 15 m)to survey the structural and dasometric characteristics of the overstorey,understorey,and regeneration layer.The results showed that grazing negatively affected the complexity of the forest structure and its potential to regenerate and maintain a high level of biodiversity.The differences in stand structure observed between the grazing areas were closely related to livestock density.The most sensitive components of the system were the understorey and the regeneration layers.Contrarily,the current grazing management did not affect the dominant tree structure or its composition.Our findings identified medium-term monitoring and regeneration management as the two significant aspects to consider when assessing sustainable livestock.New forests can be established by excluding graz-ing for about 20–25 years.展开更多
Heart injury such as myocardial infarction leads to cardiomyocyte loss,fibrotic tissue deposition,and scar formation.These changes reduce cardiac contractility,resulting in heart failure,which causes a huge public hea...Heart injury such as myocardial infarction leads to cardiomyocyte loss,fibrotic tissue deposition,and scar formation.These changes reduce cardiac contractility,resulting in heart failure,which causes a huge public health burden.Military personnel,compared with civilians,is exposed to more stress,a risk factor for heart diseases,making cardiovascular health management and treatment innovation an important topic for military medicine.So far,medical intervention can slow down cardiovascular disease progression,but not yet induce heart regeneration.In the past decades,studies have focused on mechanisms underlying the regenerative capability of the heart and applicable approaches to reverse heart injury.Insights have emerged from studies in animal models and early clinical trials.Clinical interventions show the potential to reduce scar formation and enhance cardiomyocyte proliferation that counteracts the pathogenesis of heart disease.In this review,we discuss the signaling events controlling the regeneration of heart tissue and summarize current therapeutic approaches to promote heart regeneration after injury.展开更多
It is my great pleasure to introduce you the 19th volume of Neural Regeneration Research(NRR)and the first issue of 2024.The new volume still features a large number of manuscripts reporting on neural regeneration,whi...It is my great pleasure to introduce you the 19th volume of Neural Regeneration Research(NRR)and the first issue of 2024.The new volume still features a large number of manuscripts reporting on neural regeneration,which we hope will be of interest to you.展开更多
Neuro regeneration is a very complex phenomenon characterized by the generation of new neurons and synapses,involving connections between adjacent cells and axonal projections.Neuroregeneration supplies additional lon...Neuro regeneration is a very complex phenomenon characterized by the generation of new neurons and synapses,involving connections between adjacent cells and axonal projections.Neuroregeneration supplies additional longterm resources to replace those altered by the injury and ensure lasting functional recovery.展开更多
Runx2 is a major regulator of osteoblast differentiation and function;however,the role of Runx2 in peripheral nerve repair is unclea r.Here,we analyzed Runx2expression following injury and found that it was specifical...Runx2 is a major regulator of osteoblast differentiation and function;however,the role of Runx2 in peripheral nerve repair is unclea r.Here,we analyzed Runx2expression following injury and found that it was specifically up-regulated in Schwann cells.Furthermore,using Schwann cell-specific Runx2 knocko ut mice,we studied peripheral nerve development and regeneration and found that multiple steps in the regeneration process following sciatic nerve injury were Runx2-dependent.Changes observed in Runx2 knoc kout mice include increased prolife ration of Schwann cells,impaired Schwann cell migration and axonal regrowth,reduced re-myelination of axo ns,and a block in macrophage clearance in the late stage of regeneration.Taken together,our findings indicate that Runx2 is a key regulator of Schwann cell plasticity,and therefore peripheral nerve repair.Thus,our study shows that Runx2 plays a major role in Schwann cell migration,re-myelination,and peripheral nerve functional recovery following injury.展开更多
基金support from the National Natural Science Foundation of China(U20A20239)the Key Research and Development Project of Hubei Province,China(2022BAA032).
文摘To extend the service life of the upper checker bricks in the regenerator of glass furnaces with petroleum coke as fuel,the corrosion resistance of magnesia-chrome and alumina-chrome bricks with the similar apparent porosity was systematically researched.The results show that the Cr2O3 content and the microstructure present significant effects on the corrosion resistance.The molten corrosion reagent forms silicate and vanadate phases with low melting points between MgO crystals in magnesia-chrome bricks,and the volume strain generated by the melting and solidification process leads to the cracking and spalling of refractories,which intensifies the corrosion process.The encapsulation of alumina particles by alumina-chrome solid solutions in alumina-chrome bricks avoids contact with the low melting point liquid phases and improves the corrosion resistance of refractories.
文摘In this article, researches on improvement of 1RX regenerator used in cleaning processes of cotton ginning enterprises were carried out. The effect of changing the parameters of the new working body—rubber-plate drum and machine inlet on the efficiency of cotton separation was studied in the research, and the maximum level of efficiency of separation was determined. In this paper work, the main factors affecting the efficient operation of the regenerator were identified, their value limits were determined, and research was conducted using the mathematical planning method. As a result, effective operation of the improved 1RX cotton regenerator was observed at the value of the given factors, that is, the separation efficiency was 99.5%, the cleaning efficiency was higher than 88.7%, and the amount of seed cotton in the waste was reduced lower than 2.5%.
基金Project supported by the National Natural Science Foundation of China (Grant No. 51925605)。
文摘The quantitative investigation of parameters in the renegerator is essential for the optimization of thermoacoustic devices, while the majority of the previous research only considered parameters of the working field, working gas and the hydraulic radius. Based on the linear thermoacoustic theory, this paper extracts a normalized parameter for low-amplitude conditions, which is called the regenerator operation factor. By extracting the regenerator operation factor and relative hydraulic radius, the influence of frequency on the efficiency can be controlled and offset. It can be found that thermoacoustic devices with different frequencies can perform the same efficiency by adjusting the radius in proportion to the axial length.Finally, this paper synthetically optimizes the dimension of the thermoacoustic regenerator by taking the regenerator operation factor, relative hydraulic radius and acoustic field parameter as variables. Conclusions in this paper are of great significance for explaining the best working conditions of engines and directing the miniaturization and optimal design of thermoacoustic devices.
基金important scientech problemtackling subject foundation under the state 9th 5-year plan(no.96-918-02-04).
文摘The special subject'research on life prediction technology of important in-service pressure vessels' mainly analyzes the failure mechanism of large-sized important and critical in-service pressure vessels under the action of working medium and investigates safety assessment and life prediction technology with a view to enhance the operation reliability of in-service pressure vessels in China. Based on a series of accident investigation and test & measuring research, the cause of cracking of catalytic regenerator is analyzed and the in-line non-destructive examination method and failure prevention measures for the cracking of catalytic regenerator are proposed.
基金Project supported by the Postdoctoral Science Foundation of Central South University
文摘A new method was proposed to directly measure the effective resistance and distinguish the porous frequency in the regenerator of the microminiature thermoacoustic refrigerator. Measured results were compared with the flux gain factor and transmission loss of the real system. The results show that the agreement between the range of the porous frequency and frequency of the system is good, the method can be used to predict the porous frequency of the regenerator in production.
文摘An active thermo-acoustic network model of regenerator which is a key component to accomplish the con-version between thermal-and acoustic power in thermo-acoustic system has been established in this paper. The experiment was carried out to quantify the network. A method called least square is employed in order to identify the H matrix describing the system. The results obtained here show that the active thermo-acoustic network can reliably depict the characteristics of a thermo-acoustic system.
基金This work was supported by the Science and Technology Development Project of SINOPEC,China(No.319026).
文摘An approach for the simulation and optimization of continuous catalyst-regenerative process of reforming is proposed in this paper.Compared to traditional method such as finite difference method,the orthogonal collocation method is less time-consuming and more accurate,which can meet the requirement of real-time optimization(RTO).In this paper,the equation-oriented method combined with the orthogonal collocation method and the finite difference method is adopted to build the RTO model for catalytic reforming regenerator.The orthogonal collocation method was adopted to discretize the differential equations and sequential quadratic programming(SQP)algorithm was used to solve the algebraic equations.The rate constants,active energy and reaction order were estimated,with the sum of relative errors between actual value and simulated value serving as optimization objective function.The model can quickly predict the fields of component concentration,temperature and pressure inside the regenerator under different conditions,as well as the real-time optimized conditions for industrial reforming regenerator.
文摘During long-term use,the clay checker bricks for regenerators of coke ovens on gas side react with the impurities containing Fe and K20,causing foaming,softening and deformation,which is not only related with the impurity content and properties of the clay checker bricks,but also related with the type and the composition of the dust in the gas.After long term use,the clay checker bricks of coke ovens on air side have relative lower impurities containing Fe and K20.The inferior clay checker bricks,with high impurity content and high porosity,are easy to pulverize and deteriorate due to the oxidationreduction reaction with the iron oxide and the gas.The gas quality shall be concerned for long service life of the coke oven regenerators.
文摘Regenerator checkerwork for glass melting furnaces should have high resistance against thermal stress and chemical attack,high mechanical stability,high efficiency to recover the heat from waste gas and low tendency for clogging.This article reviews the innovation of the regenerator checkerwork from the past decades.The state of the art for optimised material choice and optimised checker shapes will be reported.
文摘The catalyst regeneration process running under the partial oxidation mode in traditional fluid catalytic cracking(FCC)units needs a carbon monoxide(CO)boiler to burn the flue gas,resulting in a large volume of CO_(2) emissions.In this study,the performance of a set of industrial serial-type FCC regenerators and the changes in flue gas composition were analyzed by establishing a model of the regenerators and the flue gas energy recovery section.Considering the value of utilizing CO,based on the simulation,this paper proposes two schemes for maximizing CO content in the flue gas of regenerators.The two sets of optimal process operating parameters were obtained using a genetic algorithm.Compared with the original process,the CO contents of flue gas in the two optimized processes increased to 6.6%and 12.5%,CO_(2) emissions were reduced by 48.4%and 96.7%,and the costs of CO production were 0.57$/m^(3) and 0.84$/m^(3),respectively.
文摘In order to provide a novel and more effective alternative to the commonly used relay protection testing device that outputs only the sinusoidal testing signals, the concept of fault waveform regenerator is proposed in this paper, together with its hardware structure and software flow chart. Fault waveform regenerator mainly depends on its power amplifiers (PAs) to regenerate the fault waveforms recorded by digital fault recorder (DFR). To counteract the PA’s inherent nonlinear distortions, a digital closed-loop modification technique that is different from the predistortion technique is conceived. And the experimental results verify the effectiveness of the fault waveform regenerator based on the digital closed-loop modification technique.
基金supported by the National Natural Science Foundation of China(Grant No.51736004).
文摘Regenerators play a vital role in enhancing the overall performance of Stirling engines.Hence,this paper performed an energy and exergy analysis to elucidate the significance of regenerator characteristics concerning system performance,contributing to the optimal regenerator’s design and selection.The relationship between regenerator structure,regenerator exergy destruction,and output power,thermal efficiency,and exergy efficiency for Stirling engines was established by integrating the thermal model of Stirling engines with a mathematical model of regenerators.In contrast to cross-flow and parallel-flow regenerators,a novel concept of inclined-flow regenerators,featuring a matrix surface inclined in the direction of gas flow,was developed to achieve higher and more balanced engine output power and energy utilization efficiency.A comprehensive investigation was conducted into the effects of matrix structure types and regenerator geometries on the performance of both regenerators and engines.The results reveal that,following structural optimization,Stirling engines equipped with the inclined-flow regenerator demonstrate a substantial 16.6%,38.3%,and 37.2%increase in power output,thermal efficiency,and exergy efficiency,respectively,compared to those equipped with cross-flow regenerators.In contrast,when compared to engines fitted with parallel-flow regenerators,they experience a 13.5%reduction in power output but achieve remarkable enhancements of 45.4%and 36.7%in thermal and exergy efficiency,respectively.This study introduces new insights into selecting regenerator structures for enhancing the output performance of Stirling engines.
基金National Natural Science Foundation of China(NSFC)(11474238,11734011,91636109)Fundamental Research Funds for the Central Universities at Xiamen University(20720160040)+2 种基金Natural Science Foundation of Fujian Province(2015J06002)Program for New Century Excellent Talents in University(NCET)(NCET-13-0495)National Key R&D Program of China(2017YFA0303700)
文摘The generation and manipulation of optical vortices are of fundamental importance in a variety of promising applications. Here, we develop a nonlinear optical paradigm to implement self-and cross-convolution of optical vortex arrays, demonstrating the features of a vortex copier and regenerator. We use a phase-only spatial light modulator to prepare the 1064 nm invisible fundamental light to carry special optical vortex arrays and use a potassium titanyl phosphate crystal to perform type Ⅱ second-harmonic generation in the Fourier domain to achieve 532 nm visible structured vortices. Based on pure cross-convolution, we succeed in copying arbitrary-order single vortices as well as their superposition states onto a prearranged array of fundamental Gaussian spots. Also, based on the simultaneous effect of self-and cross-convolutions, we can expand the initial vortex lattices to regenerate more vortices carrying various higher topological charges. Our presented method of realizing an optical vortex copier and regenerator could find direct applications in optical manipulation, optical imaging, optical communication, and quantum information processing with structured vortex arrays.
基金supported by the grants from National Research Foundation(NRF,#2021R1A5A2022318,#RS-2023-00220408,#RS-2023-00247485),Republic of Korea.
文摘Inflammatory skin disorders can cause chronic scarring and functional impairments,posing a significant burden on patients and the healthcare system.Conventional therapies,such as corticosteroids and nonsteroidal anti-inflammatory drugs,are limited in efficacy and associated with adverse effects.Recently,nanozyme(NZ)-based hydrogels have shown great promise in addressing these challenges.NZ-based hydrogels possess unique therapeutic abilities by combining the therapeutic benefits of redox nanomaterials with enzymatic activity and the water-retaining capacity of hydrogels.The multifaceted therapeutic effects of these hydrogels include scavenging reactive oxygen species and other inflammatory mediators modulating immune responses toward a pro-regenerative environment and enhancing regenerative potential by triggering cell migration and differentiation.This review highlights the current state of the art in NZ-engineered hydrogels(NZ@hydrogels)for anti-inflammatory and skin regeneration applications.It also discusses the underlying chemo-mechano-biological mechanisms behind their effectiveness.Additionally,the challenges and future directions in this ground,particularly their clinical translation,are addressed.The insights provided in this review can aid in the design and engineering of novel NZ-based hydrogels,offering new possibilities for targeted and personalized skin-care therapies.
基金supported by the National Natural Science Foundation of China(51671052,51750110513,52250610222)the Fundamental Research Funds for the Central Universities(N182502042)the Liao Ning Revitilization Talents Program(XLYC1902105)。
文摘Graphene-based materials possess significant potential for the treatment of dye wastewater due to their exceptional adsorption properties toward stubborn pollutants.However,their utilization is hindered by high preparation costs,low yields,environmental pollution during synthesis,and challenges in regenerating the adsorbent.This study proposes a novel approach to address these limitations by developing nitrogen-doped three-dimensional(3D)polyvinyl alcohol(PVA)crosslinked graphene sponges(N-PGA)using a cross-linking method with ammonium carbonate.This method offers a relatively mild,environmentally friendly approach.Ammonium carbonate serves as both a reducing and modifying agent,facilitating the formation of the intrinsic structure of N-PGA and acting as a nitrogen source.Meanwhile,PVA is utilized as the cross-linking agent.The results demonstrate that N-PGA exhibits a favorable internal 3D hierarchical porous structure and possesses robust mechanical properties.The measured specific surface area(BET)of N-PGA was as high as406.538 m^(2)·g^(-1),which was favorable for its efficient adsorption of Congo red(CR)dye molecules.At an initial concentration of 50 mg·L^(-1),N-PGA achieved an impressive removal rate of 89.6%and an adsorption capacity of 112 mg·g^(-1)for CR dye.Furthermore,it retained 79%of its initial adsorption capacity after 10 cycles,demonstrating excellent regeneration performance.In summary,the synthesized N-PGA displays remarkable efficacy in the adsorption of CR dye in wastewater,opening up new possibilities for utilizing 3D porous graphene nanomaterials as efficient adsorbents in wastewater treatment.
基金This research is related to the project GO NEWTON“Agroforestry Network in Tuscany”,financed by the Tuscany Region through the Measure 16.2 of Rural Development Plan 2014-2020 to promote agroforestry systems by spreading knowledge to farmers and promoting innovation in the Tuscan territory.
文摘On an agrosilvopastoral farm in central Italy where Maremmana cattle graze in Turkey oak forests,we evaluated the impact of different livestock densities on stand structure,tree diversity and natural regeneration in four types of grazed areas based on the grazing regime adopted:calf-grazed,high-intensity-grazed,low-intensity-grazed,ungrazed control.For each area,we set up three permanent circular plots(radius of 15 m)to survey the structural and dasometric characteristics of the overstorey,understorey,and regeneration layer.The results showed that grazing negatively affected the complexity of the forest structure and its potential to regenerate and maintain a high level of biodiversity.The differences in stand structure observed between the grazing areas were closely related to livestock density.The most sensitive components of the system were the understorey and the regeneration layers.Contrarily,the current grazing management did not affect the dominant tree structure or its composition.Our findings identified medium-term monitoring and regeneration management as the two significant aspects to consider when assessing sustainable livestock.New forests can be established by excluding graz-ing for about 20–25 years.
基金supported by the Natural Science Foundation of Beijing,China(7214223,7212027)the Beijing Hospitals Authority Youth Programme(QML20210601)+3 种基金the Chinese Scholarship Council(CSC)scholarship(201706210415)the National Key Research and Development Program of China(2017YFC0908800)the Beijing Municipal Health Commission(PXM2020_026272_000002,PXM2020_026272_000014)the National Natural Science Foundation of China(82070293).
文摘Heart injury such as myocardial infarction leads to cardiomyocyte loss,fibrotic tissue deposition,and scar formation.These changes reduce cardiac contractility,resulting in heart failure,which causes a huge public health burden.Military personnel,compared with civilians,is exposed to more stress,a risk factor for heart diseases,making cardiovascular health management and treatment innovation an important topic for military medicine.So far,medical intervention can slow down cardiovascular disease progression,but not yet induce heart regeneration.In the past decades,studies have focused on mechanisms underlying the regenerative capability of the heart and applicable approaches to reverse heart injury.Insights have emerged from studies in animal models and early clinical trials.Clinical interventions show the potential to reduce scar formation and enhance cardiomyocyte proliferation that counteracts the pathogenesis of heart disease.In this review,we discuss the signaling events controlling the regeneration of heart tissue and summarize current therapeutic approaches to promote heart regeneration after injury.
文摘It is my great pleasure to introduce you the 19th volume of Neural Regeneration Research(NRR)and the first issue of 2024.The new volume still features a large number of manuscripts reporting on neural regeneration,which we hope will be of interest to you.
基金supported by PIAno di inCEntivi per la Rlcerca di Ateneo 2020/2022 Linea di In tervento3"Starting Grant""REPAIR"(to GM)。
文摘Neuro regeneration is a very complex phenomenon characterized by the generation of new neurons and synapses,involving connections between adjacent cells and axonal projections.Neuroregeneration supplies additional longterm resources to replace those altered by the injury and ensure lasting functional recovery.
基金supported by the National Natural Science Foundation of China,No.82104795 (to RH)。
文摘Runx2 is a major regulator of osteoblast differentiation and function;however,the role of Runx2 in peripheral nerve repair is unclea r.Here,we analyzed Runx2expression following injury and found that it was specifically up-regulated in Schwann cells.Furthermore,using Schwann cell-specific Runx2 knocko ut mice,we studied peripheral nerve development and regeneration and found that multiple steps in the regeneration process following sciatic nerve injury were Runx2-dependent.Changes observed in Runx2 knoc kout mice include increased prolife ration of Schwann cells,impaired Schwann cell migration and axonal regrowth,reduced re-myelination of axo ns,and a block in macrophage clearance in the late stage of regeneration.Taken together,our findings indicate that Runx2 is a key regulator of Schwann cell plasticity,and therefore peripheral nerve repair.Thus,our study shows that Runx2 plays a major role in Schwann cell migration,re-myelination,and peripheral nerve functional recovery following injury.