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Economic Regionalism: A Win-Win Option 被引量:1
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作者 Zhao Jinpong is a Research Professor and Director of Department for Foreign Economic Studies, Development Research Center of the State Council. 《Contemporary International Relations》 2003年第11期6-10,共5页
Economic regionalism in East Asia lags far behind the quickened pace of southward thrust of the North America Free Trade Area (NAFTA) and eastern extension of the European Union. Despite aspirations for regional econo... Economic regionalism in East Asia lags far behind the quickened pace of southward thrust of the North America Free Trade Area (NAFTA) and eastern extension of the European Union. Despite aspirations for regional economic cooperation on the part of the nations concerned , differences in their stage of economic development, the burning issues facing them and varying domestic pressures against trade liberalization have resulted in insufficient urgency and driving force for 展开更多
关键词 FTA A Win-Win Option FORM Economic regionalism been
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A Study on the Cooperative Mechanism of the Belt and Road Initiative from the Perspective of New Regionalism 被引量:1
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作者 Deng Tingting Ma Chunxue Wu Lingwei 《Contemporary Social Sciences》 2018年第1期51-70,共20页
The loosely-typed, duty-overlapped and subject-isolated cooperative mechanism of the Belt and Road Initiative has significantly limited the advancement of the initiative and affected the full play of its cooperative e... The loosely-typed, duty-overlapped and subject-isolated cooperative mechanism of the Belt and Road Initiative has significantly limited the advancement of the initiative and affected the full play of its cooperative effect. New Regionalism is a theory of international relations that concerns international cooperation at the regional level. Its characteristics of multilevel, multi-topic and multi-subject conform to the cooperation needs of the Belt and Road Initiative and provide a guiding framework for the cooperative mechanism of the Initiative. According to the theoretical connotation of New Regionalism, the cooperative mechanism of the Belt and Road Initiative should enrich its cooperation forms, deepen cooperation topics and promote the participation of "State-Market-Society". This mechanism is expected to form various cooperation models, comprehensive governance and diversified participants to enable the smooth advancement of the Belt and Road Initiative. 展开更多
关键词 New regionalism the Belt and Road Initiative cooperative mechanism
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Exploration on Regionalism Characteristic Landscape Building in Tianjin
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作者 GENG Meiyun,and HE Shuang College of Horticulture,Northeast Agricultural University,Harbin 150030,China 《Journal of Northeast Agricultural University(English Edition)》 CAS 2010年第2期69-72,共4页
With the globalization expanding,the coverage of the city grows the same increasingly.The situation that different streets and cities have almost the same scenes is becoming more and more serious.Creating regional cha... With the globalization expanding,the coverage of the city grows the same increasingly.The situation that different streets and cities have almost the same scenes is becoming more and more serious.Creating regional characteristics of landscape is so urgent.Because only the local that is the national,and the national one belongs to the world.In the globalization process,the landscape construction contains both the "regional" integration and destruction,at the same time,it is a "regional" re-creation process.T... 展开更多
关键词 LANDSCAPE GLOBALIZATION regionalism SAMPLE
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Constructing a New Polish Architecture: Critical Regionalism and Resistance to Globalization after 1989
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作者 Krystyna Januszkiewicz 《Journal of Civil Engineering and Architecture》 2014年第12期1518-1526,共9页
This paper explores the critical regionalism which could play a role in the continued development of global era Polish architecture, and the advancements achieved by those few contemporary Polish architects who have s... This paper explores the critical regionalism which could play a role in the continued development of global era Polish architecture, and the advancements achieved by those few contemporary Polish architects who have sought to combine modern tastes and techniques with culturally meaningful designs. The new culture of Poland is very much reflected in the design of many of its new buildings that have been completed since the political and economic changes in 1989. The architecture of Poland appears to have lurched from an inappropriate socialist modernism that was so horridly imposed during the communist era to an equally inappropriate post modernist hegemony in the new enterprise culture. In accordance with Poland, now is rejection of the centrally imposed system of building and architecture, and with the greater emphasis on individual initiative in the new culture, it seems a pity that the country should automatically adopt western modes of architectural expression. This paper suggests that with its newly founded freedom, Poland should be careful that it does not suffer a loss of identity and that, in its architecture, it should seek a way forward through a critical regionalism. 展开更多
关键词 ARCHITECTURE CULTURE critical regionalism GLOBALIZATION RESISTANCE Poland.
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Democratic Constitution and Ethnic Organizations in Malawi: Preserving Good Culture or Promoting, Regionalism, Nepotism and Tribalism
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作者 Willie S. D. Zeze 《History Research》 2015年第3期169-187,共19页
Due to the advent of the 1994 democratic constitution particularly sections 32 and 33 which provide for every person's right to freedom of conscience, religion, belief and thought, and also to academic freedom Malawi... Due to the advent of the 1994 democratic constitution particularly sections 32 and 33 which provide for every person's right to freedom of conscience, religion, belief and thought, and also to academic freedom Malawi has significantly witnessed mushroom development of tribal organizations, aiming at preserving and protecting local religious beliefs and cultural practices. The Chewa Heritage Foundation (CHEFO) and the Muhlako wa Alhomwe (MWA) are among the well-known numerous ethnic organizations through which the traditional beliefs, cultural and religious practices enjoy significant respect from Chewa and Lhomwe people. Although the new Constitution has cleared a road for the establishment of these ethnic organizations, it seems activities of all ethnic associations are significantly promoting tribalism and nepotism, in addition to being used as campaign tools by political parties. This article intends to critically assess and evaluate the role and the impact of the Chewa Heritage Foundation and Muhlako wa Alhomwe on rule of law, govemance and culture in Malawi. The following question will guide the discussion: Why are the Chewa Heritage Foundation and Mulhako wa Alhomwe cultural associations while exercising their constitutional rights promoting tribalism, regionalism and nepotism and used as campaign machinery by both opposition and ruling political parties? Its hypothesis is, in spite of preserving protecting cultural practices as guaranteed in constitution, tribal organizations need to be watchful so that they should not promote tribalism, nepotism and being used as campaign tools by crooked and opportunist politicians. 展开更多
关键词 democratic constitution CULTURE regionalism nepotism and tribalism
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From Going Beyond the “Nation-State” to the Construction of the “East Asia Community”? Myths About “East Asia New Regionalism”
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作者 FENG Chao 《Cultural and Religious Studies》 2020年第4期217-227,共11页
With the deepening of globalization,geographically speaking,East Asian countries have proceeded from their respective realist positions and tried to promote the successful practice of economic cooperation between coun... With the deepening of globalization,geographically speaking,East Asian countries have proceeded from their respective realist positions and tried to promote the successful practice of economic cooperation between countries after the Cold War into a discussion of new regionalism in East Asia and Asia-Pacificism.Although the prototype of the“East Asia Community”led by Association of Southeast Asian Nations(ASEAN)gradually emerged,the successful practice of the East Asia Summit proved that the low-binding regional integration model led by ASEAN has a high probability of becoming a classic sample of the“East Asia Community”.It not only maintains regional stability,promotes regional cooperation,shapes regional norms,but also builds a collective identity within the region.However,in today’s world,isolationism which takes the supremacy of national interests as the supremacy has risen.It is difficult to internalize the value identity into a super-national model that breaks through the principles of realism,breakthroughs in interests,and the power framework.The thorny issues pose various challenges to the nation-states in the region trying to integrate into regional integration.The openness of East Asian regionalism has led to the persistent illness of its generalization.In the context of insufficient political mutual trust among regional countries,intensified competition among major powers,and continued weakening of ASEAN leadership,it is often prone to controversy and doubt when proposing new cooperation initiatives or ideas.The idea of the“East Asia Community”that once guided East Asian cooperation and was temporarily ignored now is still the most realistic choice.Although the theoretical construction and practical roads of East Asian regionalism are full of thorns,difficulties coexist with opportunities.With the extensive participation of countries in the region,the optimization and reconstruction of the East Asian cooperation model will be worth looking forward to. 展开更多
关键词 nation-state dilemma pattern East Asia Community regionalism
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Regionalism and Non-regionalism of Ba Jin’s Works
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作者 Wang Xuedong 《Contemporary Social Sciences》 2021年第5期137-146,共10页
Modern Chinese literature witnessed the popularity of Sichuan writers like Li Jieren and Sha Ting,who were well known for their distinctive regional characters and the experiences portrayed in their works,telling unad... Modern Chinese literature witnessed the popularity of Sichuan writers like Li Jieren and Sha Ting,who were well known for their distinctive regional characters and the experiences portrayed in their works,telling unadulterated“Sichuan Stories”and depicting lives in the context of Ba-Shu culture.People even consider their works to be the modern“Chronicles of Huayang(Huayang Guo Zhi)in modern time.”However,when we look at Ba Jin,his works are not like typical Sichuan writers(such as Guo Moruo,Li Jieren,Sha Ting,and Ai Wu).He did not pay much attention to depicting the customs and lives in Sichuan,and we can seldom find the flavor of Ba-Shu culture in his works.When editing Chinese Literature and Regional Culture in the 20th Century in 1995,Yan Jiayan so commented,“To study Sichuan literature Ba-Shu culture,it is not appropriate to pick Ba Jin(though he was a great writer with great contributions)”(Li,1997).As it were,the relationship between Ba Jin and the Ba-Shu culture is delicate.Ba Jin showed his distinctive choices and pursuit in this relationship.By studying the“regionalism”and“non-regionalism”of Ba Jin’s works,we can better understand Ba Jin and his writing.It is also enlightening for us to review the future development of Ba-Shu culture. 展开更多
关键词 Ba Jin modern Chinese literature Ba-Shu culture regionalism
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Complexities of practicing architectural regionalism in India:An interview study
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作者 Sanyam Bahga Gaurav Raheja 《Frontiers of Architectural Research》 CSCD 2020年第3期568-578,共11页
This paper presents the results and analysis from an interview study conducted with practitioners of architectural regionalism in India.The interviews sought to gain indepth understanding of the strategies,mechanisms,... This paper presents the results and analysis from an interview study conducted with practitioners of architectural regionalism in India.The interviews sought to gain indepth understanding of the strategies,mechanisms,and tools they employ to realize contextualized architecture that responds to local needs and potential.A sample composed of nine eminent Indian architects who regularly integrate the ideas of critical regionalism in their designs is selected and subsequently interviewed with regard to the varied aspects of their architectural practice.Findings are useful for practitioners and scholars of contemporary architecture in India for understanding the means employed by leading regionalist architects,while placing their work in the context of local building traditions,urban landscape,sociocultural conditions,technology,and climate. 展开更多
关键词 Architectural regionalism Critical regionalism Indian architecture Architects’interviews Semi-structured interviews Architecture practice
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Does digitalization mitigate regional inequalities?Evidence from China 被引量:1
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作者 Haimeng Liu Xinyang Wang +1 位作者 Zheye Wang Yu Cheng 《Geography and Sustainability》 CSCD 2024年第1期52-63,共12页
Regional inequality significantly influences sustainable development and human well-being.In China,there exists pronounced regional disparities in economic and digital advancements;however,scant research delves into t... Regional inequality significantly influences sustainable development and human well-being.In China,there exists pronounced regional disparities in economic and digital advancements;however,scant research delves into the interplay between them.By analyzing the economic development and digitalization gaps at regional and city levels in China,extending the original Cobb-Douglas production function,this study aims to evaluate the impact of digitalization on China's regional inequality using seemingly unrelated regression.The results indicate a greater emphasis on digital inequality compared to economic disparity,with variable coefficients of 0.59 for GDP per capita and 0.92 for the digitalization index over the past four years.However,GDP per capita demonstrates higher spatial concentration than digitalization.Notably,both disparities have shown a gradual reduction in recent years.The southeastern region of the Hu Huanyong Line exhibits superior levels and rates of economic and digital advancement in contrast to the northwestern region.While digitalization propels economic growth,it yields a nuanced impact on achieving balanced regional development,encompassing both positive and negative facets.Our study highlights that the marginal utility of advancing digitalization is more pronounced in less developed regions,but only if the government invests in the digital infrastructure and education in these areas.This study's methodology can be utilized for subsequent research,and our findings hold the potential to the government's regional investment and policy-making. 展开更多
关键词 Regional inequality Regional disparities Digital divide DIGITALIZATION Sustainable development Economic growth Seemingly unrelated regression
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Construction and Application of a Regional Kilometer-Scale Carbon Source and Sink Assimilation Inversion System(CCMVS-R) 被引量:1
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作者 Lifeng Guo Xiaoye Zhang +8 位作者 Junting Zhong Deying Wang Changhong Miao Licheng Zhao Zijiang Zhou Jie Liao Bo Hu Lingyun Zhu Yan Chen 《Engineering》 SCIE EI CAS CSCD 2024年第2期263-275,共13页
CO_(2)is one of the most important greenhouse gases(GHGs)in the earth’s atmosphere.Since the industrial era,anthropogenic activities have emitted excessive quantities of GHGs into the atmosphere,resulting in climate ... CO_(2)is one of the most important greenhouse gases(GHGs)in the earth’s atmosphere.Since the industrial era,anthropogenic activities have emitted excessive quantities of GHGs into the atmosphere,resulting in climate warming since the 1950s and leading to an increased frequency of extreme weather and climate events.In 2020,China committed to striving for carbon neutrality by 2060.This commitment and China’s consequent actions will result in significant changes in global and regional anthropogenic carbon emissions and therefore require timely,comprehensive,and objective monitoring and verification support(MVS)systems.The MVS approach relies on the top-down assimilation and inversion of atmospheric CO_(2)concentrations,as recommended by the Intergovernmental Panel on Climate Change(IPCC)Inventory Guidelines in 2019.However,the regional high-resolution assimilation and inversion method is still in its initial stage of development.Here,we have constructed an inverse system for carbon sources and sinks at the kilometer level by coupling proper orthogonal decomposition(POD)with four-dimensional variational(4DVar)data assimilation based on the weather research and forecasting-greenhouse gas(WRF-GHG)model.Our China Carbon Monito ring and Verification Support at the Regional level(CCMVS-R)system can continuously assimilate information on atmospheric CO_(2)and other related information and realize the inversion of regional and local anthropogenic carbon emissions and natural terrestrial ecosystem carbon exchange.Atmospheric CO_(2)data were collected from six ground-based monito ring sites in Shanxi Province,China to verify the inversion effect of regio nal anthropogenic carbon emissions by setting ideal and real experiments using a two-layer nesting method(at 27 and 9 km).The uncertainty of the simulated atmospheric CO_(2)decreased significantly,with a root-mean-square error of CO_(2)concentration values between the ideal value and the simulated after assimilation was close to 0.The total anthropogenic carbon emissions in Shanxi Province in 2019 from the assimilated inversions were approximately 28.6%(17%-38%)higher than the mean of five emission inventories using the bottomup method,showing that the top-down CCMVS-R system can obtain more comprehensive information on anthropogenic carbon emissions. 展开更多
关键词 CCMVS-R Regional carbon assimilation system Anthropogenic carbon emissions CO_(2) POD 4DVar
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A core-satellite self-assembled SERS aptasensor containing a“biological-silent region”Raman tag for the accurate and ultrasensitive detection of histamine 被引量:1
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作者 Chen Chen Yingfang Zhang +3 位作者 Ximo Wang Xuguang Qiao Geoffrey I.N.Waterhouse Zhixiang Xu 《Food Science and Human Wellness》 SCIE CSCD 2024年第2期1029-1039,共11页
Herein,a novel interference-free surface-enhanced Raman spectroscopy(SERS)strategy based on magnetic nanoparticles(MNPs)and aptamer-driven assemblies was proposed for the ultrasensitive detection of histamine.A core-s... Herein,a novel interference-free surface-enhanced Raman spectroscopy(SERS)strategy based on magnetic nanoparticles(MNPs)and aptamer-driven assemblies was proposed for the ultrasensitive detection of histamine.A core-satellite SERS aptasensor was constructed by combining aptamer-decorated Fe_(3)O_(4)@Au MNPs(as the recognize probe for histamine)and complementary DNA-modified silver nanoparticles carrying 4-mercaptobenzonitrile(4-MBN)(Ag@4-MBN@Ag-c-DNA)as the SERS signal probe for the indirect detection of histamine.Under an applied magnetic field in the absence of histamine,the assembly gave an intense Raman signal at“Raman biological-silent”region due to 4-MBN.In the presence of histamine,the Ag@4-MBN@Ag-c-DNA SERS-tag was released from the Fe_(3)O_(4)@Au MNPs,thus decreasing the SERS signal.Under optimal conditions,an ultra-low limit of detection of 0.65×10^(-3)ng/mL and a linear range 10^(-2)-10^5 ng/mL on the SERS aptasensor were obtained.The histamine content in four food samples were analyzed using the SERS aptasensor,with the results consistent with those determined by high performance liquid chromatography.The present work highlights the merits of indirect strategies for the ultrasensitive and highly selective SERS detection of small biological molecules in complex matrices. 展开更多
关键词 Surface-enhanced Raman spectroscopy Raman biological-silent region APTAMER Histamine detection Universal SERS-tag
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Projected changes in extreme snowfall events over the Tibetan Plateau based on a set of RCM simulations 被引量:1
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作者 Yuanhai Fu Xuejie Gao 《Atmospheric and Oceanic Science Letters》 CSCD 2024年第5期3-9,共7页
Extreme snowfall events over the Tibetan Plateau(TP)cause considerable damage to local society and natural ecosystems.In this study,the authors investigate the projected changes in such events over the TP and its surr... Extreme snowfall events over the Tibetan Plateau(TP)cause considerable damage to local society and natural ecosystems.In this study,the authors investigate the projected changes in such events over the TP and its surrounding areas based on an ensemble of a set of 21st century climate change projections using a regional climate model,RegCM4.The model is driven by five CMIP5 global climate models at a grid spacing of 25 km,under the RCP4.5 and RCP8.5 pathways.Four modified ETCCDI extreme indices-namely,SNOWTOT,S1mm,S10mm,and Sx5day-are employed to characterize the extreme snowfall events.RegCM4 generally reproduces the spatial distribution of the indices over the region,although with a tendency of overestimation.For the projected changes,a general decrease in SNOWTOT is found over most of the TP,with greater magnitude and better cross-simulation agreement over the eastern part.All the simulations project an overall decrease in S1mm,ranging from a 25%decrease in the west and to a 50%decrease in the east of the TP.Both S10mm and Sx5day are projected to decrease over the eastern part and increase over the central and western parts of the TP.Notably,S10mm shows a marked increase(more than double)with high cross-simulation agreement over the central TP.Significant increases in all four indices are found over the Tarim and Qaidam basins,and northwestern China north of the TP.The projected changes show topographic dependence over the TP in the latitudinal direction,and tend to decrease/increase in low-/high-altitude areas. 展开更多
关键词 Extreme snowfall Regional climate model Tibetan plateau Climate change
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Diagnostic Study of an Extreme Explosive Cyclone over the Kuroshio/Kuroshio Extension Region 被引量:1
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作者 ZHANG Shuqin LIAO Qinghua +4 位作者 LIU Chunlei GAO Xiaoyu LONG Jingchao LI Pengyuan XU Jianjun 《Journal of Ocean University of China》 SCIE CAS CSCD 2024年第3期605-617,共13页
Explosive cyclones(ECs)occur frequently over the Kuroshio/Kuroshio Extension region.The most rapidly intensified EC over the Kuroshio/Kuroshio Extension region during the 42 years(1979-2020)of cold seasons(October-Apr... Explosive cyclones(ECs)occur frequently over the Kuroshio/Kuroshio Extension region.The most rapidly intensified EC over the Kuroshio/Kuroshio Extension region during the 42 years(1979-2020)of cold seasons(October-April)was studied to reveal the variations of the key factors at different explosive-developing stages.This EC had weak low-level baroclinicity,mid-level cyclonic-vorticity advection,and strong low-level water vapor convergence at the initial explosive-developing stage.The low-level baroclinicity and mid-level cyclonic-vorticity advection increased substantially during the maximum-deepening-rate stage.The diagnostic analyses using the Zwack-Okossi equation showed that diabatic heating was the main contributor to the initial rapid intensification of this EC.The cyclonic-vorticity advection and warm-air advection enhanced rapidly in the middle and upper troposphere and contributed to the maximum rapid intensification,whereas the diabatic heating weakened slightly in the mid-low troposphere.The relative contribution of the diabatic heating decreased from the initial explosive-developing stage to the maximum-deepening-rate stage due to the enhancement of other factors(the cyclonic-vorticity advection and warm-air advection).Furthermore,the physical factors contributing to this EC varied with the explosive-developing stage.The non-key factors at the initial explosive-developing stage need attention to forecast the rapid intensification. 展开更多
关键词 explosive cyclone diabatic heating cyclonic-vorticity advection rapid intensification the Kuroshio/Kuroshio Extension region
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Interdecadal variability of summer precipitation in the Three River Source Region: Influences of SST and zonal shifts of the East Asian subtropical westerly jet 被引量:1
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作者 Yumeng Liu Xianhong Meng +5 位作者 Lin Zhao S-Y.Simon Wang Lixia Zhang Zhaoguo Li Chan Wang Yingying An 《Atmospheric and Oceanic Science Letters》 CSCD 2024年第5期47-53,共7页
Summer precipitation in the Three Rivers Source Region(TRSR)of China is vital for the headwaters of the Yellow,Yangtze,and Lancang rivers and exhibits significant interdecadal variability.This study investigates the i... Summer precipitation in the Three Rivers Source Region(TRSR)of China is vital for the headwaters of the Yellow,Yangtze,and Lancang rivers and exhibits significant interdecadal variability.This study investigates the influence of the East Asian westerly jet(EAWJ)on TRSR rainfall.A strong correlation is found between TRSR summer precipitation and the Jet Zonal Position Index(JZPI)of the EAWJ from 1961 to 2019(R=0.619,p<0.01).During periods when a positive JZPI indicates a westward shift in the EAWJ,enhanced water vapor anomalies,warmer air,and low-level convergence anomalies contribute to increased TRSR summer precipitation.Using empirical orthogonal function and regression analyses,this research identifies the influence of large-scale circulation anomalies associated with the Atlantic–Eurasian teleconnection(AEA)from the North Atlantic(NA).The interdecadal variability between the NA and central tropical Pacific(CTP)significantly affects TRSR precipitation.This influence is mediated through the AEA via a Rossby wave train extending eastward along the EAWJ,and another south of 45°N.Moreover,the NA–CTP Opposite Phase Index(OPI),which quantifies the difference between the summer mean sea surface temperatures of the NA and the CTP,is identified as a critical factor in modulating the strength of this teleconnection and influencing the zonal position of the EAWJ. 展开更多
关键词 Summer precipitation East Asian subtropical westerly jet Three River Source Region Atlantic-Eurasian teleconnection
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基于SCAR标记和DNA条形码技术的苍术基原鉴别研究
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作者 陈研 冯露露 +1 位作者 黄荣 齐伟辰 《世界科学技术-中医药现代化》 CSCD 北大核心 2024年第2期490-501,共12页
目的开发出能同时鉴别北苍术和关苍术的分子标记方法,并探究不同种质资源苍术的遗传进化关系。方法对不同地区北苍术Atractylodes chinensis(Bunge)Koidz及关苍术A.japonica Koidz.ex Kitam基因组DNA的差异片段进行测序,结合SRAP、ISSR... 目的开发出能同时鉴别北苍术和关苍术的分子标记方法,并探究不同种质资源苍术的遗传进化关系。方法对不同地区北苍术Atractylodes chinensis(Bunge)Koidz及关苍术A.japonica Koidz.ex Kitam基因组DNA的差异片段进行测序,结合SRAP、ISSR、DAMD分子标记方法,优化PCR反应体系,筛选并转换成特异性标记,同时,采用条形码方法分析种间序列差异。结果通过SRAP、ISSR、DAMD三种分子标记方法的PCR扩增,共筛选出198对能稳定扩增且重现性好的引物,转换出7对能稳定、快速鉴别北苍术和关苍术的SCAR引物。条形码方法检测出北苍术ITS2序列长度为454 bp,关苍术ITS2序列长度为453 bp,与其他苍术属植物之间遗传距离较远。NJ树结果显示,北苍术、关苍术及其他苍术属植物均各自聚为一支,表现出良好的单系性。依据ITS2二级结构,4种苍术属植物在螺旋区的茎环数目、大小、位置均有明显差异,可以直观地进行区分。结论所开发的特异性SCAR标记为苍术属植物优良品种的筛选提供了新方法,DNA条形码能稳定、准确鉴别北苍术。 展开更多
关键词 北苍术 关苍术 Internal transcribed spacer 2(ITS2) Sequence-related amplified polymorphism(SRAP) Inter-simple sequence repeat(ISSR) Direct amplification of minisatellite region DNA(DAMD) Sequence characterized amplified regions(SCAR)
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甲状腺乳头状癌超声图像表现在预测颈部Ⅵ区淋巴结转移危险度的临床价值
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作者 刘杰 于景超 +3 位作者 王猛 李卫 鲁金乐 陈雅婷 《中国耳鼻咽喉头颈外科》 CSCD 2024年第7期470-473,共4页
目的 分析甲状腺乳头状癌(PTC)超声图像表现在预测颈部Ⅵ区淋巴结转移(lymph node metastasis in the cervicalregion Ⅵ,CLNM-Ⅵ)危险度的临床价值。方法 选取2022年4月~2023年6月在河北省沧州中西医结合医院接受手术治疗并经病理证实... 目的 分析甲状腺乳头状癌(PTC)超声图像表现在预测颈部Ⅵ区淋巴结转移(lymph node metastasis in the cervicalregion Ⅵ,CLNM-Ⅵ)危险度的临床价值。方法 选取2022年4月~2023年6月在河北省沧州中西医结合医院接受手术治疗并经病理证实的350例PTC患者,根据术后病理结果,将患者分为CLNM-Ⅵ组和非CLNM-Ⅵ组。收集并对比两组术前超声图像表现及临床病理特征,应用Logistic回归分析PTC患者CLNM-Ⅵ危险因素,受试者工作特征(ROC)曲线分析PTC超声图像表现对CLNM-Ⅵ的预测价值。结果 单因素分析显示,CLNM-Ⅵ组男性、实性或囊实性、年龄≤45岁、低回声、甲状腺背景正常、点状强回声的构成比均大于非CLNM-Ⅵ组(P均<0.05)。Logistic回归分析显示,男性、实性或囊实性、年龄≤45岁、低回声、甲状腺背景正常、病灶内可见点状强回声是CLNM-Ⅵ的独立危险因素(P均<0.05);进一步经ROC曲线分析显示,以上预测CLNM-Ⅵ的AUC分别为0.565、0.580、0.529、0.585、0.582、0.582,联合预测AUC为0.708。结论PTC超声图像表现在CLNM-Ⅵ风险评估中具有重要意义,可为PTC的预后判断提供一定的参考依据。 展开更多
关键词 甲状腺肿瘤(Thyroid Neoplasms) 超声检查(Ultrasonography) 风险评估(Risk Assessment) 预测(Forecasting) 颈部Ⅵ区(regionⅥof the neck) 淋巴结转移(lymph node metastasis)
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Neural stem cell-derived exosomes promote mitochondrial biogenesis and restore abnormal protein distribution in a mouse model of Alzheimer's disease 被引量:1
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作者 Bo Li Yujie Chen +10 位作者 Yan Zhou Xuanran Feng Guojun Gu Shuang Han Nianhao Cheng Yawen Sun Yiming Zhang Jiahui Cheng Qi Zhang Wei Zhang Jianhui Liu 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第7期1593-1601,共9页
Mitochondrial dysfunction is a hallmark of Alzheimer’s disease.We previously showed that neural stem cell-derived extracellular vesicles improved mitochondrial function in the cortex of AP P/PS1 mice.Because Alzheime... Mitochondrial dysfunction is a hallmark of Alzheimer’s disease.We previously showed that neural stem cell-derived extracellular vesicles improved mitochondrial function in the cortex of AP P/PS1 mice.Because Alzheimer’s disease affects the entire brain,further research is needed to elucidate alterations in mitochondrial metabolism in the brain as a whole.Here,we investigated the expression of several important mitochondrial biogenesis-related cytokines in multiple brain regions after treatment with neural stem cell-derived exosomes and used a combination of whole brain clearing,immunostaining,and lightsheet imaging to clarify their spatial distribution.Additionally,to clarify whether the sirtuin 1(SIRT1)-related pathway plays a regulatory role in neural stem cell-de rived exosomes interfering with mitochondrial functional changes,we generated a novel nervous system-SIRT1 conditional knoc kout AP P/PS1mouse model.Our findings demonstrate that neural stem cell-de rived exosomes significantly increase SIRT1 levels,enhance the production of mitochondrial biogenesis-related fa ctors,and inhibit astrocyte activation,but do not suppress amyloid-βproduction.Thus,neural stem cell-derived exosomes may be a useful therapeutic strategy for Alzheimer’s disease that activates the SIRT1-PGC1αsignaling pathway and increases NRF1 and COXIV synthesis to improve mitochondrial biogenesis.In addition,we showed that the spatial distribution of mitochondrial biogenesis-related factors is disrupted in Alzheimer’s disease,and that neural stem cell-derived exosome treatment can reverse this effect,indicating that neural stem cell-derived exosomes promote mitochondrial biogenesis. 展开更多
关键词 Alzheimer’s disease mitochondrial biogenesis neural stem cell-derived exosome SIRT1-PGC1α regional brain distribution whole brain clearing and imaging
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Bird species composition and conservation challenges in the Gaoligong Mountains, one of the most diverse bird areas in the world 被引量:1
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作者 Fei Wu Jian-Yun Gao +13 位作者 Dao Yan Le Yang Lu-Ming Liu Shun-Yu Yao Chang-Sheng Zuo Jun Sun Ge Gao Jian-Yong Su Li Luo Ying-Chun Li Ming Liu Yuan-Fang Hu Ming Wei Xiao-Jun Yang 《Zoological Research(Diversity and Conservation)》 2024年第1期20-50,共31页
The Gaoligong Mountains(GLGM),located in southwestern China,extend north to south along the western border of the Hengduan Mountains,spanning approximately 600 km.In this study,we consolidated findings from 17 bird su... The Gaoligong Mountains(GLGM),located in southwestern China,extend north to south along the western border of the Hengduan Mountains,spanning approximately 600 km.In this study,we consolidated findings from 17 bird surveys conducted in the GLGM between 2010 and 2022.We found that the GLGM harbors tremendous bird diversity,with a total of 796 documented bird species in the region.Nearly a quarter(23.0%)of these species are listed as state key protected species or as Chinese and global threatened species.Analysis of species richness at the county level showed a decreasing trend with increasing latitude,with the greatest diversity in Yingjiang(661 species).Observations indicated that the GLGM belongs to the Oriental realm,primarily composed of bird species from southern and southwestern China.The GLGM plays an important role in avian conservation by sheltering exceptional bird diversity,providing corridors and flyways for bird migration and dispersal,and mitigating the effects of climate change.In response to the conservation needs of birds and other wildlife,the Chinese government has established numerous protected areas within the GLGM.Despite these efforts,avian conservation still faces considerable challenges in the GLGM due to limitations in the protected area network,transboundary nature of the regions,and existing gaps in monitoring and research. 展开更多
关键词 BIRDS Gaoligong Mountains Zoogeographic region Conservation challenge
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Assessment of plant diversity of endemic species of the Saharo-Arabian region in Egypt
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作者 Asmaa S ABO HATAB Yassin M AL-SODANY +2 位作者 Kamal H SHALTOUT Soliman A HAROUN Mohamed M EL-KHALAFY 《Journal of Arid Land》 SCIE CSCD 2024年第7期1000-1021,I0002-I0044,共65页
Savanna, semi-deserts, and hot deserts characterize the Saharo-Arabian region, which includes Morocco, Mauretania, Algeria, Tunisia, Libya, Egypt, Palestine, Kuwait, Saudi Arabia, Qatar, Bahrain, the United Arab Emira... Savanna, semi-deserts, and hot deserts characterize the Saharo-Arabian region, which includes Morocco, Mauretania, Algeria, Tunisia, Libya, Egypt, Palestine, Kuwait, Saudi Arabia, Qatar, Bahrain, the United Arab Emirates, Oman, Yemen, southern Jordan, Syria, Iraq, Iran, Afghanistan, Pakistan, and northern India. Its neighboring regions, the Sudano-Zambezian region belonging to the Paleotropical Kingdom and the Mediterranean and Irano-Turanian regions included in the Holarctic Kingdom, share a large portion of their flora with the Saharo-Arabian region. Despite the widespread acknowledgment of the region's global importance for plant diversity, an up to date list of the Saharo-Arabian endemics is still unavailable. The available data are frequently insufficient or out of date at both the whole global and the national scales. Therefore, the present study aims at screening and verifying the Saharo-Arabian endemic plants and determining the phytogeographical distribution of these taxa in the Egyptian flora. Hence, a preliminary list of 429 Saharo-Arabian endemic plants in Egypt was compiled from the available literature. Indeed, by excluding the species that were recorded in any countries or regions outside the Saharo-Arabian region based on different literature, database reviews, and websites, the present study has reduced this number to 126 taxa belonging to 87 genera and 37 families. Regarding the national geographic distribution, South Sinai is the richest region with 83 endemic species compared with other eight phytogeographic regions in Egypt, followed by the Isthmic Desert(the middle of Sinai Peninsula, 53 taxa). Sahara regional subzone(SS1) distributes all the 126 endemic species, Arabian regional subzone(SS2) owns 79 taxa, and Nubo-Sindian subzone(SS3) distributes only 14 endemics. Seven groups were recognized at the fourth level of classification as a result of the application of the two-way indicator species analysis(TWINSPAN) to the Saharo-Arabian endemic species in Egypt, i.e., Ⅰ Asphodelus refractus group, Ⅱ Agathophora alopecuroides var. papillosa group, Ⅲ Anvillea garcinii group, Ⅳ Reseda muricata group, V Agathophora alopecuroides var. alopecuroides group, Ⅵ Scrophularia deserti group, and Ⅶ Astragalus schimperi group. It's crucial to clearly define the Saharo-Arabian endemics and illustrate an updated verified database of these taxa for a given territory for providing future management plans that support the conservation and sustainable use of these valuable species under current thought-provoking devastating impacts of rapid anthropogenic and climate change in this region. 展开更多
关键词 ENDEMISM phytogeographical regions Saharo-Arabian floristic region Egyptian flora plant diversity two-way indicator species analysis(TWINSPAN)
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COVID-19 and regional resilience:Trends,priorities,and the geography of research
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作者 Irina D.Turgel Olga A.Chernova 《Journal of Safety Science and Resilience》 EI CSCD 2024年第3期295-305,共11页
The global economic crisis of 2008-2013 led to the emergence of the concept of resilience,which focuses on the ability of socio-economic system store cover socially,economically,and environmentally after external impa... The global economic crisis of 2008-2013 led to the emergence of the concept of resilience,which focuses on the ability of socio-economic system store cover socially,economically,and environmentally after external impacts.The COVID-19 pandemic spurred scholarly interest in regional resilience as a new conceptual framework for the sustainability theory.This paper aims to examine the influence of the pandemic on the trends and geography of regional resilience studies.We analyzed data derived from Science Direct and used vOSviewer to perform clus-tering and bibliometric network analysis.The countries that suffered the most from the pandemic and showed the largest regional socioeconomic disparities have become new centers of knowledge on regional resilience.Moreover,the pandemic has led to a visible shift in the research focus.Thus,after 2020,more attention has been paid to the structural and topological characteristics of regions that enable them to reorganize their resources more effectively in times of crisis.This study investigates the potential of the resilient development concept as a framework for gaining insights into the factors supporting regional adaptability. 展开更多
关键词 Regional economy Regional resilience Bibliometric analysis COVID-19 Spatial analysis
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