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Identification of LepA as PPIase reveals a common molecular mechanism of translational GTPases regulating L11 switch on the ribosome
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作者 Yan Qin Institute of Biophysics, Chinese, 15 Datun Road, Chaoyang District, Beijing, 100101, China 《生物物理学报》 CAS CSCD 北大核心 2009年第S1期226-226,共1页
LepA, the highly conserved translational GTPase (trGTPase), triggers one-codon back-movement of the elongating ribosome. Here we identify a new enzymatic activity
关键词 PPIASE Identification of LepA as PPIase reveals a common molecular mechanism of translational GTPases regulating L11 switch on the ribosome
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Behavioral Switch of Food Preference upon Sugar Deficiency Is Regulated by GPCRs in Drosophila 被引量:1
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作者 Chang Liu Xiaobing Bai +2 位作者 Jinghan Sun Xiaofan Zhang Yan Li 《Journal of Genetics and Genomics》 SCIE CAS CSCD 2015年第7期409-412,共4页
Sugar and protein are the major macronutrients' sources, and their balanced intake is important for animal's health. It has been observed that animals are able to change food preference in an imbalanced nutritional ... Sugar and protein are the major macronutrients' sources, and their balanced intake is important for animal's health. It has been observed that animals are able to change food preference in an imbalanced nutritional condition to selectively consume nutrients that are deficient in the body (Dethier, 1976). Early studies in both Drosophila and mouse have demonstrated that animals exhibit food rejection to imbalanced diets lacking essential amino acids (Hao et al., 2005; Bjordal et al., 2014). Furthermore, the food preference change upon protein depri- vation has been characterized using a two choice assay in Drosophila (Ribeiro and Dickson, 2010; Vargas et al., 2010). Different from protein food, sugar is the main energy source, and sugar deficiency severely affects animal survival (Lee et al., 2008). However, whether animals adopt a strategy of fast food preference switch upon sugar deprivation had not been investigated, and the neural mechanisms underlying this behavior regulation remain poorly understood. 展开更多
关键词 GPCRS Behavioral switch of Food Preference upon Sugar Deficiency Is Regulated by GPCRs in Drosophila
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Non-equilibrium effect in the allosteric regulation of the bacterial flagellar switch
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作者 Yuan Junhua (袁军华) Zhang Rongjing (张榕京) 《Science Foundation in China》 CAS 2017年第3期48-48,共1页
Subject Code:A02With funding support from the National Natural Science Foundation of China,the research group led by Prof.Yuan Junhua(袁军华)and Zhang Rongjing(张榕京)from the University of Science and Technology of C... Subject Code:A02With funding support from the National Natural Science Foundation of China,the research group led by Prof.Yuan Junhua(袁军华)and Zhang Rongjing(张榕京)from the University of Science and Technology of China(USTC)has discovered non-equilibrium effect in the regulation of the bacterial flagellar switch, 展开更多
关键词 Non-equilibrium effect in the allosteric regulation of the bacterial flagellar switch
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Research on the dynamic characteristics of pneumatic proportional regulator in pneumatic-loading system and design of fuzzy adaptive controller 被引量:2
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作者 WANG Na XU LuYu +2 位作者 XIE Fei SHI Yan WANG YiXuan 《Science China(Technological Sciences)》 SCIE EI CAS CSCD 2022年第4期956-965,共10页
Pneumatic proportional control servo regulator is the core component of a pneumatic-loading experimental system,which is very important in solving the overcharging problem.However,previous research on control of pneum... Pneumatic proportional control servo regulator is the core component of a pneumatic-loading experimental system,which is very important in solving the overcharging problem.However,previous research on control of pneumatic proportional regulator in a pneumatic-loading experimental system led to failure in analysis of the influence of opening error of the switch regulator because it did not analyze the regulator basic working principle and process.The traditional control method cannot fully solve the overcharging problem nor ensure adequate control performance of the regulator.After seriously studying the working principle and key mechanical parameters of the valve,a fuzzy parameter-adaptive controller is designed by introducing a linear mixture of the pressure and opening errors of the switch regulator to reduce pressure overshoot and optimize its control performance.According to the fuzzy-control strategy based on the working characteristics and mechanical parameters of the valve,the overshoot phenomenon of the pneumatic-loading system is solved,and the pressure overshoot is eliminated.The error of the output air pressure of the regulator is 1.24%,which is small.The adjustable pressure range of the regulator is 0.2–0.6 MPa.The maximum deviation is 0.012 MPa.The linearity of the case is 1.34%F.S. 展开更多
关键词 pneumatic proportional servo regulator pneumatic-loading experimental system mathematical model fuzzy parameter-adaptive controller opening error of the switch regulator
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