Complementary monogamy and polygamy properties among multipartite systems

Monogamy and polygamy relations are essential properties of quantum entanglement,which characterize the distributions of entanglement in multipartite systems.In this paper,we establish the general monogamy relations forγ-th(0≤γ≤α,α≥1)power of quantum entanglement based on unified-(q,s)entanglement and polygamy relations forδ-th(δ≥β,0≤β≤1)power of entanglement of assistance based on unified-(q,s)entanglement of assistance,which provides a complement to the previous research in terms of different parameter regions ofγandδ.These results are then applied to specific quantum correlations,e.g.,entanglement of formation,Renyi-q entanglement of assistance and Tsallis-q entanglement of assistance to get the corresponding monogamy and polygamy inequalities.Moreover,typical examples are presented for illustration.

Cost analysis of radical resection of malignant breast tumors under the China Healthcare Security Diagnosis Related Groups payment system

BACKGROUND Breast cancer is one of the most common malignant tumors in women worldwide and poses a severe threat to their health.Therefore,this study examined patients who underwent breast cancer surgery,analyzed hospitalization costs and structure,and explored the impact of China Healthcare Security Diagnosis Related Groups(CHS-DRG)management on patient costs.It aimed to provide medical institutions with ways to reduce costs,optimize cost structures,reduce patient burden,and improve service efficiency.AIM To study the CHS-DRG payment system’s impact on breast cancer surgery costs.METHODS Using the CHS-DRG(version 1.1)grouping criteria,4073 patients,who underwent the radical resection of breast malignant tumors from January to December 2023,were included in the JA29 group;1028 patients were part of the CHS-DRG payment system,unlike the rest.Through an independent sample t-test,the length of hospital stay as well as total hospitalization,medicine and consumables,medical,nursing,medical technology,and management expenses were compared.Pearson’s correlation coefficient was used to test the cost correlation.RESULTS In terms of hospitalization expenses,patients in the CHS-DRG payment group had lower medical,nursing,and management expenses than those in the diagnosis-related group(DRG)non-payment group.For patients in the DRG payment group,the factors affecting the total hospitalization cost,in descending order of relevance,were medicine and consumable costs,consumable costs,medicine costs,medical costs,medical technology costs,management costs,nursing costs,and length of hospital stay.For patients in the DRG nonpayment group,the factors affecting the total hospitalization expenses in descending order of relevance were medicines and consumable expenses,consumable expenses,medical technology expenses,the cost of medicines,medical expenses,nursing expenses,length of hospital stay,and management expenses.CONCLUSION The CHS-DRG system can help control and reduce unnecessary medical expenses by controlling medicine costs,medical consumable costs,and the length of hospital stay while ensuring medical safety.

DCS, a novel classifier system based on disulfidptosis reveals tumor microenvironment heterogeneity and guides frontline therapy for clear cell renal carcinoma

Background: Emerging evidence suggests that cell deaths are involved in tumorigenesis and progression, which may be treated as a novel direction of cancers. Recently, a novel type of programmed cell death, disulfidptosis, was discovered. However, the detailed biological and clinical impact of disulfidptosis and related regulators remains largely unknown. Methods: In this work, we first enrolled pancancer datasets and performed multi-omics analysis, including gene expression, DNA methylation, copy number variation and single nucleic variation profiles. Then we deciphered the biological implication of disulfidptosis in clear cell renal cell carcinoma (ccRCC) by machine learning. Finally, a novel agent targeting at disulfidptosis in ccRCC was identified and verified. Results: We found that disulfidptosis regulators were dysregulated among cancers, which could be explained by aberrant DNA methylation and genomic mutation events. Disulfidptosis scores were depressed among cancers and negatively correlated with epithelial mesenchymal transition. Disulfidptosis regulators could satisfactorily stratify risk subgroups in ccRCC, and a novel subtype, DCS3, owning with disulfidptosis depression, insensitivity to immune therapy and aberrant genome instability were identified and verified. Moreover, treating DCS3 with NU1025 could significantly inhibit ccRCC malignancy. Conclusion: This work provided a better understanding of disulfidptosis in cancers and new insights into individual management based on disulfidptosis.

Test of the Relative Permeability Curve of a Gas and Oil Condensate System and its Effect on the Recovery of Oil and Gas

The relative permeability curve has been measured with simulation oil (refined oil) and gas (nitrogen or air) at room temperature and a lowpressure, both of which are very important parameters for depicting the flow of fluid through porous media in a hydrocarbon reservoir. This basic measurement is often applied in exploitation evaluation, but the underground conditions with high temperature and pressure, and the phase equilibrium of oil and gas, are not taken into consideration when the relative permeability curve is tested. There is an important theoretical and practical sense in testing the diphase relative permeability curve of the equilibrium of oil and gas under the conditions of high temperature and pressure. The test method for the relative permeability curve is proposed in this paper. The relative permeability of the equilibrium of oil and gas and the standard one are tested in two fluids, and the differences between these two methods are stated. The research results can be applied to the simulation and prediction of CVD in long cores and then the phenomenon can better explain that the recovery of condensate gas rich in condensate oil is higher than that of CVD test in PVT. Meanwhile, the research shows that the relative permeability curve of equilibrium oil and gas is sensitive to the rate of exploitation, and the viewpoint proves that an improved gas recovery rate can properly increase the recovery of condensate oil.

Algebraic Structure of the Dynamical Equations of Holonomic Mechanical System in Relative Motion

Aim To study an algebraic of the dynamical equations of holonomic mechanical systems in relative motion. Methods The equations of motion were presented in a contravariant algebraic form and an algebraic product was determined. Results and Conclusion The equations a Lie algebraic structure if any nonpotential generalized force doesn't exist while while the equations possess a Lie-admissible algebraic structure if nonpotential generalized forces exist .

Hypidone hydrochloride(YL-0919)ameliorates functional deficits after traumatic brain injury in mice by activating the sigma-1 receptor for antioxidation

Traumatic brain injury involves complex pathophysiological mechanisms,among which oxidative stress significantly contributes to the occurrence of secondary injury.In this study,we evaluated hypidone hydrochloride(YL-0919),a self-developed antidepressant with selective sigma-1 receptor agonist properties,and its associated mechanisms and targets in traumatic brain injury.Behavioral experiments to assess functional deficits were followed by assessment of neuronal damage through histological analyses and examination of blood-brain barrier permeability and brain edema.Next,we investigated the antioxidative effects of YL-0919 by assessing the levels of traditional markers of oxidative stress in vivo in mice and in vitro in HT22 cells.Finally,the targeted action of YL-0919 was verified by employing a sigma-1 receptor antagonist(BD-1047).Our findings demonstrated that YL-0919 markedly improved deficits in motor function and spatial cognition on day 3 post traumatic brain injury,while also decreasing neuronal mortality and reversing blood-brain barrier disruption and brain edema.Furthermore,YL-0919 effectively combated oxidative stress both in vivo and in vitro.The protective effects of YL-0919 were partially inhibited by BD-1047.These results indicated that YL-0919 relieved impairments in motor and spatial cognition by restraining oxidative stress,a neuroprotective effect that was partially reversed by the sigma-1 receptor antagonist BD-1047.YL-0919 may have potential as a new treatment for traumatic brain injury.

Effects of Relative Soil Water Content on Antioxidant Enzyme System in Malus sieversii(Lebed.) Roem

By pot experiment under artificially simulated water stress conditions, soluble protein content, MDA content and SOD, POD, CAT and APX activities in Malus sieversfi leaves were determined to reveal the response mechanism of M. sieversii to changes of relative soil water content. According to the results, with the decrease of relative soil water content, MDA content in M. sieversii leaves increased by mem- brane lipid peroxidation. Cells resist water stress-induced membrane lipid peroxidation and clear the increased reactive oxygen species by improving soluble protein content and SOD, POD, CAT and APX activities. However, various enzymes were involved in the response to water stress under different moisture conditions. In addition, the results indicated that M. sieversii had a good adaptability to higher relative soil water contents.

Study on the evaluation index system and evaluation method for self-elevating drilling unit design

In the process of designing self-elevating drilling unit, it is important, yet complicated, to use comparison and filtering to select the optimum scheme from the feasible ones. In this research, an index system and methodology for the evaluation of self-elevating drilling unit was proposed. Based on this, a multi-objective combinatorial optimization model was developed, using the improved grey relation Analysis （GRA）, in which the analytic hierarchy process （AHP） was used to determine the weights of the evaluating indices. It considered the connections within the indices, reflecting the objective nature of things, and also considered the subjective interests of ship owners and the needs of designers. The evaluation index system and evaluation method can be used in the selection of an optimal scheme and advanced assessment. A case study shows the index system and evaluation method are scientific, reasonable, and easy to put into practice. At the same time, such an evaluation index system and evaluation method will be helpful for making decisions for other mobile platforms.

Lie Symmetries and Conserved Quantities of Systems of Relative Motion Dynamics

Aim To study the Lie symmetries and conserved quantities of the dynamical equationsof relative motion for holonomic mechanical systems. Methods Lie's method of the invariance of ordinary differential equations under infinitesimal transformations was used. Results and Conclusion The determining equaiton of the Lie symmetries for the dynamical equationS of relative motion is established.The structure quation and the form conserved quantities are obtained. An example iD illustrate the application of the result is given.

Autophagy-targeting modulation to promote peripheral nerve regeneration

Nerve regeneration following traumatic peripheral nerve injuries and neuropathies is a complex process modulated by diverse factors and intricate molecular mechanisms.Past studies have focused on factors that stimulate axonal outgrowth and myelin regeneration.However,recent studies have highlighted the pivotal role of autophagy in peripheral nerve regeneration,particularly in the context of traumatic injuries.Consequently,autophagy-targeting modulation has emerged as a promising therapeutic approach to enhancing peripheral nerve regeneration.Our current understanding suggests that activating autophagy facilitates the rapid clearance of damaged axons and myelin sheaths,thereby enhancing neuronal survival and mitigating injury-induced oxidative stress and inflammation.These actions collectively contribute to creating a favorable microenvironment for structural and functional nerve regeneration.A range of autophagyinducing drugs and interventions have demonstrated beneficial effects in alleviating peripheral neuropathy and promoting nerve regeneration in preclinical models of traumatic peripheral nerve injuries.This review delves into the regulation of autophagy in cell types involved in peripheral nerve regeneration,summarizing the potential drugs and interventions that can be harnessed to promote this process.We hope that our review will offer novel insights and perspectives on the exploitation of autophagy pathways in the treatment of peripheral nerve injuries and neuropathies.

Risk Assessment of Diary Cattle Brucellosis Based on Systematic Multilevel Grey Relation Entropy Method

[Objective] The study was to explore the major factors affecting diary cattle brucellosis risk assessment,as well as their strong-to-weak sequence,so as to provide theoretical basis for assessing diary cattle brucellosis risk level in different regions.[Method] From 4 dimensions of feeding and importing,breeding,housing and polyculture situation,an evaluation index system was set up,and diary cattle brucellosis risk survey was conducted in 3 typical regions.Finally,systematic multilevel grey relation entropy method was applied to perform data analysis.[Result] The strong-to-weak sequence of Level 1 impact factor of diary cattle brucellosis was as follows：feeding and importinghousingpolyculture situationbreeding;the sequence of Level 2 impact factor was U32〉U12〉U11〉U31〉U21〉U42〉U43〉U23〉U22〉U41;the risk level sequence of 3 typical regions was Province A（County A1,A2,A3）Province B（County B1,B2,B3）Province C（County C1,C2,C3）.[Conclusion] According to the weight of Level 1 index strata,administrative departments at all levels and dairy cattle farmers should lay emphasis on the aspects of feeding,importing and housing;viewed from the perspective of Level 2 index strata,dairy cattle farmers should value the siting of cattle field,the brucellosis surveillance before importing and milking modes most.According to the diary cattle brucellosis risk level of 3 typical regions,if administrative departments at all levels strengthen peoples＇ awareness of their personal health and increase investment in this area,with new healthy cultured atmosphere built,the risk level of diary cattle brucellosis will surly decline.

A Study on the Multi-Compartment Linear Circulation Pharmacokinetic Model for the Targeting Drug Delivery System

By analyzing the observed phenomena and the data collected in the study, a multi-compartment linear circulation model for targeting drug delivery system was developed and the function formulas of the drug concentration-time in blood and target organ by computing were figured out. The drug concentration-time curve for target organ can be plotted with reference to the data of drug concentration in blood according to the model. The pharmacokinetic parameters of the drug in target organ could also be obtained. The practicability of the model was further checked by the curves of drug concentration-time in blood and target organ(liver) of liver-targeting nanoparticles in animal tests. Based on the liver drug concentration-time curves calculated by the function formula of the drug in target organ, the pharmacokinetic behavior of the drug in target organ(liver) was analyzed by statistical moment, and its pharmacokinetic parameters in liver were obtained. It is suggested that the (relative targeting index( can be used for quantitative evaluation of the targeting drug delivery systems.

Integration system research and development for three-dimensional laser scanning information visualization in goaf

An integration processing system of three-dimensional laser scanning information visualization in goaf was developed. It is provided with multiple functions, such as laser scanning information management for goaf, cloud data de-noising optimization, construction, display and operation of three-dimensional model, model editing, profile generation, calculation of goaf volume and roof area, Boolean calculation among models and interaction with the third party soft ware. Concerning this system with a concise interface, plentiful data input/output interfaces, it is featured with high integration, simple and convenient operations of applications. According to practice, in addition to being well-adapted, this system is favorably reliable and stable.

Study on effectiveness evaluation of weapon systems based on grey relational analysis and TOPSIS

To evaluate the effectiveness of weapon systems, the advantages and disadvantages of grey relational analysis and TOPSIS for multiattribute decision-making is pointed out, and an effectiveness evaluation model of weapon systems by combining grey relational analysis and TOPSIS is proposed. The model aggregates the grey relational grade and the distance to a new integrated closeness and reflects not only the trend but also the situation of the alternative. The example illuminates that the model is effective for the effectiveness evaluation of weapon systems.

Quantum entanglement in the system of two two-level atoms interacting with a single-mode vacuum field

The entanglement properties of the system of two two-level atoms interacting with a single-mode vacuum field are explored. The quantum entanglement between two two-level atoms and a single-mode vacuum field is investigated by using the quantum reduced entropy; the quantum entanglement between two two-level atoms, and that between a single two-level atom and a single-mode vacuum field are studied in terms of the quantum relative entropy. The influences of the atomic dipole-dipole interaction on the quantum entanglement of the system are also discussed. Our results show that three entangled states of two atoms-field, atom-atom, and atom-field can be prepared via two two-level atoms interacting with a single-mode vacuum field.

Multi-attributed decision making for mining methods based on grey system and interval numbers

In the case of unknown weights, theories of multi-attributed decision making based on interval numbers and grey related analysis were used to optimize mining methods. As the representative of independence for the indicator, the smaller the correlation of indicators is, the greater the weight is. Hence, the weights of interval numbers of indicators were determined by using correlation coefficient. Relative closeness based on positive and negative ideal methods was calculated by introducing distance between interval numbers, which made decision making more rational and comprehensive. A new method of ranking interval numbers based on normal distribution was proposed for the optimization of mining methods, whose basic properties were discussed. Finally, the feasibility and effectiveness of this method were verified by theories and practice.

Modeling and Analysis of Airlift System Operating in Three-Phase Flow

Based on the momentum theorem, the fluid governing equation in a lifting pipe is proposed by use of the method combining theoretical analysis with empirical correlations related to the previous research, and the performance of an airlift pump can be clearly characterized by the triangular relationship among the volumetric flux of air, water and solid particles, which are obtained respectively by using numerical calculation. The meso-scale river sand is used as tested particles to examine the theoretical model. Results of the model are compared with the data in three-phase flow obtained prior to the development of the present model, by an independent experimental team that used the physical conditions of the present approach. The analytical error can be controlled within 12% for predicting the volumetric flux of water and is smaller than that （±16%） of transporting solid particles in three-phase flow. The experimental results and computations are in good agreement for air-water two-phase flow within a margin of ±8%. Reasonable agreement justifies the use of the present model for engineering design purposes.

Conformal invariance and conserved quantities of dynamical system of relative motion

This paper discusses in detail the conformal invariance by infinitesimal transformations of a dynamical system of relative motion. The necessary and sufficient conditions of conformal invariance and Lie symmetry are given simultaneously by the action of infinitesimal transformations. Then it obtains the conserved quantities of conformal invariance by the infinitesimal transformations. Finally an example is given to illustrate the application of the results.

Multi-objective Fuzzy Optimization Algorithm for Separation-Recycle System

Separation-recycle system is an important part in chemical process, and its optimization is a multiobjective problem. In this paper the process optimization procedure is proposed. The fuzzy optimization algorithm with the concept of relative importance degree (RID) is utilized to transfer multi-objective optimization (MO-O) model into a single-objective optimization (SO-O) framework. The treatment of process condensate in synthesisa mmonia plant is taken as example to illustrate the optimization procedure, and the satisfactory result demonstrates feasibility and effectiveness of the suggested method.

Response surface method using grey relational analysis for decision making in weapon system selection

A proper weapon system is very important for a na- tional defense system. Generally, it means selecting the optimal weapon system among many alternatives, which is a multiple- attribute decision making （MADM） problem. This paper proposes a new mathematical model based on the response surface method （RSM） and the grey relational analysis （GRA）. RSM is used to obtain the experimental points and analyze the factors that have a significant impact on the selection results. GRA is used to an- alyze the trend relationship between alternatives and reference series. And then an RSM model is obtained, which can be used to calculate all alternatives and obtain ranking results. A real world application is introduced to illustrate the utilization of the model for the weapon selection problem. The results show that this model can be used to help decision-makers to make a quick comparison of alternatives and select a proper weapon system from multiple alternatives, which is an effective and adaptable method for solving the weapon system selection problem.