Interaction between XRCC1 Polymorphisms and Intake of Long-Term Stored Rice in the Risk of Esophageal Squamous Cell Carcinoma:A Case-Control Study

Objective This study aimed to explore the roles of three common single nucleotide polymorphisms in the X-ray repair cross-complementing group-1 gene （XRCC1） and of life style factors and their possible interactions in the risk of esophageal squamous cell carcinoma （ESCC） in China. Methods A population-based case-control study of 432 cases and 915 controls was conducted in Yangzhong County, Jiangsu Province, China. Subjects were interviewed by trained interviewers using a structured questionnaire that included questions on demographics and life style. XRCC1 genotypes were analyzed using a polymerase chain reaction based restriction fragment length polymorphism （PCR-RFLP） assay. Unconditional logistic regression analysis was used to calculate adjusted odds ratios （aORs） and 95% confidence intervals （CIs） for associations of ESCC with XRCCI polymorphisms and lifestyle-related factors. Results Both the drinking of river water and alcohol intake history were significantly associated with an increased risk of ESCC among men with aORs of 4.20 （95% Ch 2.90-6.07） and 2.03 （95% Ch 1.43-2.89）, respectively. For women, the corresponding odds ratios were 8.37 （95% CI： 5.09-13.75） for river water drinking and 12.78 （95% CI： 2.69-60.69） for long-term stored rice intake. After the XRCC1 G28152A polymorphism was adjusted for potential confounders, subjects with GA and AA genotypes had an increased risk for ESCC （aOR： 1.21, 95% CI： 0.93-1.56）, compared with subjects with a GG genotype, and a positive multiplicative interaction between intake of long-term stored rice and the XRCC1 G28152A polymorphism was observed （P=O.009）.Conclusions Our findings suggest that both lifestyle-related factors, including drinking river water, long-term stored rice and alcohol intake, and the XRCC1 G28152A polymorphism were possible risk factors for ESCC, and that the XRCC1 G28152A polymorphism modified the effect of long-term stored rice intake on the risk of ESCC among Chinese people.

A Corpus-Based Analytical Study on Military and Security Developments Involving People＇s Republic of China

This paper contrasts Military Power of the People＇s Republic of China from the year of 2000 to 2009 and Military and Security Developments Involving People＇s Republic of China from the year 2010 to 2013 with corpus analysis. It distinguishes the new reports＇ differences from the old ones and tries to explore American＇s discourse colonization and discourse hegemony through corpus software WordSmith 5.0-Keywords and Concordance analysis of high frequency words. The significance of the study is that it enlightens military texts which will influence audiences＇ viewpoints and provides a new perspective for strategies replying American media war.

Analysis on the Consular Dimension of Sino-Indian Relations

This article explains reasons from the consular perspective why people to people exchange between China and India is not so active. Review of evolution of bilateral consular relations reveals that the basis of cross border personnel exchanges is weak with the closing of consulates of both countries in each other’s territory for nearly three decades. Relatively, small number of Chinese and Indian consular posts in each other’s territory means inconvenience for citizens to apply for visa for visiting the other and seeking consular assistance and protection. Inflexible visa policy of both countries toward citizens of the other party also accounts for the none-activeness. Considering the important role played by civilian exchange in advancing bilateral relations, China and India should establish more consular posts in each other’s territory and further relax visa requirements.

Study on the Value of ＂Education Involved by All Related People＂ in the Practice of the Socialist Core Values

The ideological and political education for students in institutions of higher learning is a complicated, systematic project. To unequivocally cultivate the socialist core values of these students and deeply influence their ideological understanding and behaviors, the concept of ＂education involved by all related people＂ is necessarily implemented in all aspects, and the joint force of ＂imparting knowledge and educating people＂ , ＂educating people by management＂ , and ＂educating people by service＂ is formed. As a result, the actual effectiveness of the ideological and political education is improved in institutions of higher learning.

Deep Solicitude for The Poor Rural People——An Interview with Lin Yuechan, a government official from Fujianofficial from Fujian

Fujian Province has made tremendous achievements in poverty alleviation and human rights protection, which provided valuable experience for the rest of the world. For this reason, our correspondents interviewed Lin Yuechan, deputy director of the Office of Rural Affairs under the People's Government of Fujian Province.

Malaria Prevalence and Associated Risk Factors among Batwa Indigenous People of Kanungu District in Southwestern Uganda: Does “Place” Matter?

Introduction: Malaria is an important disease, causing high morbidity and mortality, especially in Sub-Saharan Africa. Measuring malaria prevalence using malaria rapid diagnostic tests (mRDTs), particularly among a vulnerable population sub-group, is a vital public health step in discovering effective methods of prevention and control. This study set out to examine the association between “place” and other risk factors with malaria prevalence among Batwa Indigenous People (IP). Methods: An analytical cross-sectional study design was implemented. Two surveys January 2014 (n = 572) and April 2014 (n = 541) involving interviews and testing for malaria using mRDTs were conducted in 10 Batwa settlements where a total of 1113 Batwa of all ages were surveyed and tested. The data were first compiled in MS Excel and then imported and analyzed using STATA ver.14. Descriptive statistics, were generated, followed by bivariable and multivariable regression model analysis to establish associations between the predictor and outcome variables with p ≤ 0.05 considered statistically significant. Results: Overall prevalence was 13.94% (n = 146). There is a significant relationship between settlement (place) and malaria prevalence AOR 11.7, 95% CI (1.38 - 98.93), p-value = 0.02. More males 16.97% (n = 84) tested positive compared to females 11.23% (n = 62) but there was no statistically significant association between gender and mRDT (p-value > 0.005). Children less than 5 years registered high prevalence and there was a significant relationship between age and mRDT (p-value ≤ 0.005). Wealth proxy indicators showed no association with prevalence p-value = 0.390. Season had no association with prevalence (p-value = 0.80). However, the proportion of the day spent in the forest/woodlands was significantly associated with malaria prevalence COR 12.83, 95% CI (1.14 - 143.73) p-value = 0.04. Low elevation was significantly associated with malaria prevalence COR 2.42, 95% CI (1.32 - 4.41), p = 0.004 but sleeping under a net and level of education did not show any association with malaria prevalence. Conclusion: This study highlights the importance of place in predicting malaria prevalence among Batwa Indigenous People a marginalized and remortely located sub-population. This study has shown that place matters in determining malaria prevalence. However, other factors like age, elevation and gender also contribute to malaria prevalence. Batwa have higher prevalence than the national and even non-indigenous populations in the same district. We recommend targeting hotspots intervention approach since it has proven reasonable impact on reducing malaria prevalence.

Measuring and preventing alcohol use and related harm among young people in Asian countries:a thematic review

Background:The paper reviews alcohol consumption patterns and alcohol-related social and health issues among 15-29-year old young people in Asian countries,and discusses strategies for preventing and controlling alcohol use and related harms.Methods:We searched Google Scholar,PubMed,and Web of Science for reports,reviews and journal articles published in English between 1st Jan 1990 and 31st August 2016.Results:Forty-one reports,reviews and journal papers were identified and included in the final review.The current drinking levels and prevalence among young people are markedly different between eight included Asian countries,ranging from 4.2%in Malaysia to 49.3%in China.In a majority of the selected Asian countries,over 15%of total deaths among young men and 6%among young women aged 15-29 years are attributable to alcohol use.Alcohol use among young people is associated with a number of harms,including stress,family violence,injuries,suicide,and sexual and other risky behaviours.Alcohol policies,such as controlling sales,social supply and marketing,setting up/raising a legal drinking age,adding health warning labels on alcohol containers,and developing a surveillance system to monitor drinking pattern and risky drinking behaviour,could be potential means to reduce harmful use of alcohol and related harm among young people in Asia.Conclusions:The review reveals that drinking patterns and behaviours vary across eight selected Asian countries due to culture,policies and regional variations.The research evidence holds substantial policy implications for harm reduction on alcohol drinking among young people in Asian countries-especially for China,which has almost no alcohol control policies at present.

New Year’s Day in the United States

The custom of visiting friends, relatives and neighbors on NewYear’s Day is one of tie Old World traditions that has taken on anew form in the United States. It is called the Open House.Officially inaugurated by Washington during his first term asPresident. it is now as much a part of New Year’s Day as floralparades and football games. On January 1, 1789. PresidentWashington first opened the doors of his official residence, then inPhiladelphia, to all who wished to come. Then, when the

Celebrating Diversity of Humanity, Struggling for Peace, and Establishing Culture of Coexistence

The Qur＇an embraces cultural pluralism, emphasising that “People, We created you all from a single man and a single woman, and made you into races and tribes so that you should recognize one another. ”（Q. 49： 13）. Moreover, peace is the most fundamental value in the Qur＇an and Islam. The majority of the classical Muslim jurists, especially Hanafi school, emphasised that the reason for Muslims＇ fight against non-Muslims is Muslims＇ defense themselves against attacks, not non-Muslims＇ faith. Bediuzzaman Said Nursi （d. 1960） states that the only kind of jihad that is appropriate for the present age is spiritual or moraljihad. Furthermore, regarding Qur＇anic approach to relations between Muslims and the People of the Book, Muslim scholars, in general, advocate sincere relations and trust between Muslims and the People of the Book. In addition, Said Nursi is one of the great Muslim scholars in interfaith dialogue in the 20th century. Finally, there is the need for establishing culture of coexistence, which practised before within a religious tradition such as Islamic tradition for many centuries in the history. Through achieving a culture of coexistence and peace, most conflicts can be resolved.

论新质生产力基础上的“新质民主”与“新质法治”的辩证统一

从分析“新质生产力”的性质、内涵、特征、构成要素及意义出发,运用马克思主义立场、观点和方法,坚持习近平法治思想为指导,可以明确提出“新质生产力”的出现和发展可能引起“新质生产关系”的形成,继而通过“新质经济基础”推动上层建筑朝着“新质上层建筑”转变的重大法理判断。“新质生产力”所引发的社会变革是客观规律,民主与法治作为上层建筑的重要组成部分,也会随着“新质生产力”的不断发展而日益呈现“新质民主”与“新质法治”的特征。“全过程人民民主”是“新质民主”的重要标志,而数字法治、涉外法治构成了“新质法治”的核心要素。法学界要及早规划、超前研究,对“新质生产力”发展可能引发的包含了民主与法治等要素在内的上层建筑可能发生的深远影响,从法理上进行深入分析并拿出切实可行的应对方案。

邓小平关于增强基层党组织组织功能重要论述研究

在带领党和人民开创中国特色社会主义的过程中,邓小平围绕“建设什么样的党、怎样建设党”这一在推进改革开放和现代化建设中必须解决的核心问题,提出了一系列关于增强基层党组织组织功能的新思想、新论断、新观点。其主要内容包括:优化干部队伍建设是增强基层党组织组织功能的核心要义,提高党员素质是增强基层党组织组织功能的关键所在,密切联系群众是增强基层党组织组织功能的坚实基础,抓实组织制度建设是增强基层党组织组织功能的根本保障。这些重要论述对新时代加强基层党组织建设具有重要的启示意义。

多重约束下民警公务用枪的行动逻辑

公务用枪中存在的问题反映出公安机关在社会治理中的困境。实证研究发现,民警公务用枪的心理与行为受到多重条件的约束。文化与舆论是最外围的软性约束,影响着公务用枪的正义感。法律法规是较外围的刚性约束,决定着公务用枪的合法感。组织氛围是较内围的显性约束,决定着公务用枪的支持感。素质与训练则是最内围的硬性约束,决定着公务用枪的效能感。四个维度的用枪心理影响着民警在警务实战中的行为倾向和行为表现。涉枪事件的应对和涉枪民警的处理,又将反作用于涉枪民警及其他民警的心理与行为。研究结果为民警不愿拿枪、不敢用枪、不会用枪等问题找到一种阐释框架。

不同健康维度的高血压合并糖尿病老年患者社区医养结合服务需求

目的:探讨社区居家的高血压合并糖尿病老年患者健康相关生命质量与医养结合服务需求的关系。方法:采用多阶段分层整群随机抽样法,于2023年4月至5月抽取广州、苏州、济南、青岛等地区的1443名社区居家老年人,从中选取254例高血压合并糖尿病老年患者为研究对象。应用欧洲五维健康EQ-5D量表调查患者的健康相关生命质量,分析不同健康维度高血压合并糖尿病老年患者医养结合服务需求的差异。结果:社区居家老年患者EQ-5D健康效用值为0.674。254例老年患者中行动能力有困难的占58.3%、日常生活能力有困难的占56.3%、疼痛或不舒服的占53.5%、自我照顾能力有困难的占49.2%、焦虑或抑郁的占27.6%。行动能力有困难者在医学康复、医学护理、急救救护、临床治疗、康复训练、上门服务、助餐、助厕、助浴、助行、助急、心理关怀方面的需求高于无困难者(P<0.05);自我照顾能力有困难者在医学康复、医学护理、急救救护、康复训练、助餐、助厕、助浴、助行、助急、心理关怀方面的需求高于无困难者(P<0.05);日常活动能力有困难者在医学康复、医学护理、急救救护、康复训练、助餐、助厕、助浴、助行、助急、心理关怀、休闲娱乐方面的需求高于无困难者(P<0.05);疼痛或不舒服者在康复训练、上门服务、助厕、助浴、助行、助急方面的需求高于无疼痛或不舒服者(P<0.05)。结论:高血压合并糖尿病老年患者的健康相关生命质量较低,不同健康维度患者社区居家医养结合服务的需求不同。

成都肢体残疾人未满足辅助技术需求及其相关因素

目的调查成都市肢体残疾人未满足辅助技术需求,并分析其影响因素。方法2023年11月至2024年3月,对四川省“量体裁衣”服务平台登记的成都市肢体残疾人,采用世界卫生组织快速辅助技术评估问卷进行调查。结果共发放问卷558份,回收有效问卷527例。26.8%的残疾人有未满足辅助技术需求,移动辅具需求最高(66.0%)。缺少支持(54.9%)、价格昂贵(26.3%)和不了解辅助器具(20.3%)是未获得所需辅具的主要原因。丧偶(OR=3.615)、严重移动障碍(OR>2.926)、严重自我护理障碍(OR>2.781)是辅具需求未满足的风险因素(P<0.05)。结论应加大对辅具政策和辅具产品的宣传,关注不同障碍残疾人群的个性化辅具适配,增强辅具服务体系建设,以满足残疾人辅具需求。

人文交流视角下中国网络小说在越南的传播和接受

人文交流是我国对外交往的重要内容。中越两国是文化相通的友好邻邦,在两国悠久的人文交流史上,文学交流是其中十分重要的构成部分。基于两国人民和文化间的高度认同,以及相似的世界观、价值观、人生观和审美观,中国文学作品在越南始终有很高的接受度。近年来,中国网络小说在越南被大量翻译出版,引发了广泛的社会影响。本文基于2000—2020年中国网络小说在越南翻译出版及网络转载的统计数据,对其在越南传播的过程和特点进行梳理和分析,为更好地开展中越人文交流活动提供一种新的视角和思路。在很大程度上,中国网络小说在越南的传播虽然是越南文化市场的自觉选择,但因缺少专业性的引导和规范而存在种种问题。然而,它作为一种民间、草根式的中越人文交流活动,不仅拉近了中越两国人民之间的心理距离,更为中越青年搭建了相知相亲的桥梁,对于推动中越两国的人文交流具有长期而深远的意义。

何以治民:论汉唐循吏面临的矛盾及其选择

汉唐循吏主要面对着以下四种与百姓相关的矛盾:一是百姓利益与循吏自己、亲人等私人利益的矛盾,此时循吏选择牺牲私人利益,尽心为百姓办事。二是百姓利益与下属、同僚、上司、君主等各方利益的矛盾,此时循吏选择以百姓利益优先,牺牲下属利益,站在了同僚、上司和君主的对立面。三是百姓利益与法律制度的矛盾,此时循吏选择为了百姓而不遵守法律制度。四是百姓与百姓利益的矛盾,对于刑事案件,循吏秉公执法;民事纠纷则以调解为主。在循吏的观念中,百姓的分量最重,法律制度次之,君主最轻。循吏在处理上述四种矛盾时,分别体现出了无私奉献、不畏权威、礼优于法、灵活权变的原则。

从水师到水警:安徽长淮水上警察的源起与演变

近代长淮水警是在清末时期淮河水师基础上改组所建,并在北洋政府时期正式形成、南京国民政府时期进一步发展。从淮河水师到长淮水警经历了较大演变,具体体现为组织建制的系统化,工作职能的专业化,以及制度创设的规范化。纵观其演变,可窥见地方机构因政治局势动荡而瞬息万变,是政局变动之表现与产物。其演变过程亦反映出地方与中央、官兵民之间因利益纠葛和权力归属等问题存在严重的矛盾与冲突。囿于清末和民国时期的政局动荡和多重矛盾等因素的交织,长淮水警虽呈现警政的近代化建设,但终未彻底实现转变。

从中国式现代化理解民主:全过程人民民主的一种法理释读

全过程人民民主是社会主义民主政治的本质属性,发展全过程人民民主是中国式现代化的本质要求。系统回答在中国式现代化进程中发展全过程人民民主“何以必要”及“何以可能”的重大问题,就必须将全过程人民民主的内在逻辑与实践进路问题放置于中国式现代化的宏大场景中深入思考。全过程人民民主从民主与政治关系上为中国式现代化标识人类政治文明新向度,从民主与政党关系上为中国式现代化确立根本保证,从民主与法治关系上为中国式现代化稳预期、固根本、利长远,从民主实现方法上为中国式现代化丰富民主实践样态,从民主评判方法上为中国式现代化提供新的民主“度量衡”。未来,我国宜提升人民代表大会代表的专业化履职水平与积极性,推动政协建言资政和凝聚共识双向发力,推进基层立法联系点制度系统性完善,提升人民民主参与网络化、数智化水平,以主体赋能、形式多元、纵深发展、场景丰富的全过程人民民主推进中国式现代化行稳致远。