Spectrum-effect relationship between HPLC fingerprints and bioactive components of Radix Hedysari on increasing the peak bone mass of rat

The traditional Chinese medicine of Radix Hedysari plays an important role in invigorating gas for ascending, benefiting blood for promoting production of fluid, and promoting circulation for removing obstruction in collaterals, which is consistent with the principle of treatment for osteoporosis. This study is designed to investigate the bioactive components on increasing peak bone mass (PBM) by exploring the spectrum-effect relationship between chromatography fingerprints and effect. Multiple indicators are selected to evaluate the pharmacological activity. In fingerprints, 21 common peaks are obtained, five of which are identified. Furthermore, gray relational analysis (GRA) is a quantitative method of gray system theory and is used to describe the correlation degree of common peaks and pharmacological activities with relational value. 21 components are then divided into three different regions, of which ononin and calycosin play an extremely significant role in increasing PBM. In addition, factor analysis and hierarchical cluster analysis (HCA) are used to screen the optimal producing area for Radix Hedysari. This provides a comprehensive and efficient method to improve the quality evaluation of Radix Hedysari, confirming the bioactive components for PBM-enhancement and further develop its medicinal value.

The scaling relationship of leaf area and total mass of sample plots across world trees

The scaling relationship between leaf area and total mass of plant has important implications for understanding resource allocations in the plant.The model of West,Brown and Enquist(WBE model)considers that a 3/4 scaling exponent of metabolic rate versus total mass to be optimal for each plant and has been confirmed numerous times.Although leaf area is a better proxy of the metabolic rate than leaf mass,few studies have focused on the scaling exponent of leaf area versus total mass and even fewer have discussed the diversification of this scaling exponent across different conditions.Here,I analyzed the scaling exponent of leaf area versus total mass of sample plots across world plants.I found that as the plant grows,it allocates fewer resources to photosynthetic tissues than expected by the WBE model.The results also empirically show that this scaling exponent varies significantly for different plant leaf habit,taxonomic class and geographic region.Therefore,leaf strategy in response to environmental pressure and constraint clearly plays a significant role.

Change of Annual Extreme Water Levels and Correlation with River Discharges in the Middle-lower Yangtze River: Characteristics and Possible Affecting Factors

As one of the fastest developing regions in China, the middle-lower Yangtze River （MLYR） is vulnerable to floods and droughts. With obtained time series of annual highest water level （HWL）, annual lowest water level （LWL） and the corresponding fiver discharges from three gauging stations in MLYR that covering the period 1987-2011, the current study evaluated the change character- istics of annual extreme water levels and the correlation with fiver discharges by using the methods of Vend test, Mann-Whitney-Pettitt （MWP） test and double mass analysis. Major result indicated a decreasing/increasing trend for annual HWL/LWL of all stations in MLYR during the study period. A change point in 1999 was identified for annual HWL at the Hankou and Datong stations. The year 2006 was found to be the critical year that the relationship between annual extreme water levels and fiver discharges changed in the MLYR. With contrast to annual LWL in MLYR, further investigation revealed that the change characteristics of annual HWL were highly consistent with regional precipitation in the Yangtze River Basin, while the linkage with Three Gorges Dam （TGD） operation is not strong. Our observation also pointed out that the effect of serious down cutting of the riverbed and the enlargement of the cross-section area during the initial period of TGD operation caused the downward trend of the relationship between annual LWL and river discharge. Whereas, the relatively raised river water level before the flood season due to TGD regulation since 2006 explained for the changing upward trend of the relationship between annual HWL and river discharge.

Mass transfer mechanism and relationship of gas–liquid annular flow in a microfluidic cross-junction device

Mass transfer performance of gas–liquid two-phase flow at microscale is the basis of application of microreactor in gas–liquid reaction systems.At present,few researches on the mass transfer property of annular flow have been reported.Therefore,the mass transfer mechanism and relationship of gas–liquid annular flow in a microfluidic cross-junction device are studied in the present study.We find that the main factors,i.e.,flow pattern,liquid film thickness,liquid hydraulic retention time,phase interface fluctuation,and gas flow vorticity,which influence the flow mass transfer property,are directly affected both by gas and liquid flow velocities.But the influences of gas and liquid velocities on different mass transfer influencing factors are different.Thereout,the fitting relationships between gas and liquid flow velocities and mass transfer influencing factors are established.By comparing the results from calculations using fitting equations and simulations,it shows that the fitting equations have relatively high degrees of accuracy.Finally,the Pareto front,namely the Pareto optimal solution set,of gas and liquid velocity conditions for the best flow mass transfer property is obtained using the method of multi-objective particle swarm optimization.It is proved that the mass transfer property of the gas–liquid two-phase flow can be obviously enhanced under the guidance of the obtained Pareto optimal solution set through experimental verification.

Research on Current Situation and Legal Regulation of Cosmetics Live Streaming E-commerce in China

Analyze the compatibility between cosmetics and live streaming e-commerce from its own nature,marketing means and supply chain characteristics.According to the prominent problems,sort out the relationship between all parties in the cosmetics live e-commerce industry chain.Combined with the latest regulatory policies of live streaming e-commerce and cosmetics,the responsibilities of different subjects in cosmetics live streaming e-commerce are summarized,and relevant suggestions and countermeasures are put forward for the standardization and development of live streaming e-commerce.Cosmetics brand owners are the first responsible persons for product quality.Anchors,as a mixed identity between intermediary,advertising spokesperson and operator,should bear stricter joint and several liability when recommending products related to consumers’health.If anchors fail to clearly identify themselves in the recommendation process,thus causing consumers to mistake them for the operator of the cosmetics,they should assume the obligations of the operator.

Investigation of the Effect of Acceptance and Commitment Psychotherapy (ACT) on Quality of Life of Adult Women Suffering from Obesity

Background and Purpose: Quality of life as an important factor in health is very important. This study is looking for an appropriate and effective treatment for improving quality of life. This research aims to study the psychological effect of acceptance and commitment therapy (ACT) on quality of life of adult women suffering from obesity. Methods and Materials: This research is a kind of half-trail, with pattern of pre-test, post-test and group control. Statistical population includes all over-weight women with body mass index (BMI) range (30 - 40) who participated in family training sessions held in Shahin Shahr city. 40 patients who had the characteristics for sampling were selected and randomly placed in test and control groups (each group 20 people). Participants in each group before and after intervention quality of life questionnaire with 100 question sample World Health Organization Quality of Life (WHOQOL)-100 were evaluated. 12 sessions of acceptance and commitment therapy in group was used. The obtained data were analyzed with the use of Sciences Statistical Package for the Social (SPSS) 18 statistical software and methods of analysis of covariance. Findings: After selection of adult women having a BMI between 30 and 40 based on availability who had attended the meeting of family education, by invitation and voluntary, they were randomized into experimental and control groups. Intervention was done for experimental group. Due to the result of covariance analysis on the post-test stage, examination group showed significant improvement in variants physical health dimensions, level of independence in social and environmental relationships and spirituality (p < 0.01). Conclusion: According to the findings of this research based on the impact of acceptance and commitment intervention on promotion and improving in quality of life, this treatment can be used for improving the variants in women suffering from over-weight and obesity.

Study on the Factors Driving the Loyalty of the Customers of a Third Party Mobile Payment Platform

. In this paper, the main driving factors affecting the customer loyalty of a third party mobile payment service were chosen by combining with the actual situation of the third party mobile payment service and customer spending habits in China. The assumed relations between all affecting factors and the customer loyalty of a third party mobile payment platform were proposed, and a model for studying customer loyalty was established and also a conclusion was made through the questionnaire survey analysis data. Finally, suggestions on improving the loyalty of the customers of a third party mobile payment platform are presented.

Study on the Structural Effect of Maltoligosaccharides on Cytochrome c Complexes Stabilities by Native Mass Spectrometry

Noncovalent interactions between ligands and targeting proteins are essential for understanding molecular mechanisms of proteins.In this work,we investigated the interaction of Cytochrome c(Cyt c)with maltoligosaccharides,namely maltose(Mal Ⅱ),maltotriose(Mal Ⅲ),maltotetraose(Mal Ⅳ),maltopentaose(Mal Ⅴ),maltohexaose(Mal Ⅵ)and maltoheptaose(Mal Ⅶ).Using electrospray ionization mass spetrometry(ESI-MS)assay,the 1:1 and 1:2 complexes formed by Cyt c with maltoligosaccharide ligand were observed.The corresponding association constants were calculated according to the deconvoluted spectra.The order of the relative binding affinities of the selected oligosaccharides with Cyt c were as MalⅢ>MalⅣ>MalⅡ>MalⅤ>MalⅥ>MalⅦ.The results indicated that the stability of noncovalent protein complexes was intimately correlated to the molecular structure of bound ligand.The relevant functional groups that could form H-bonds,electrostatic or hydrophobic forces with protein’s amino residues played an important role for the stability of protein complexes.In addition,the steric structure of ligand was also critical for an appropriate interaction with the binding pocket of proteins.

Precipitation Chemistry and Corresponding Transport Patterns of Influencing Air Masses at Huangshan Mountain in East China

One hundred and ten samples of rainwater were collected for chemical analysis at the summit of Huangshan Mountain, a high-altitude site in East China, from July 2010 to June 2011. The volume-weighted-mean （VWM） pH for the whole sampling period was 5.03. SO2- and Ca2＋ were the most abundant anion and cation, respectively. The ionic concentrations varied monthly with the highest concentrations in winter/spring and the lowest in summer. Evident inter-correlations were found among most ions, indicating the common sources for some species and fully mixing characteristics of the alpine precipitation chemistry. The VWM ratio of [SO]-]/[NO3] was 2.54, suggesting the acidity of rainwater comes from both nitric and sulfuric acids. Compared with contemporary observations at other alpine continental sites in China, the precipitation at Huangshan Mountain was the least polluted, with the lowest ionic concentrations. Trajectories to Huangshan Mountain on rainy days could be classified into six groups. The rainwater with influencing air masses originating in Mongolia was the most polluted with limited effect. The emissions of Jiangxi, Anhui, Zhejiang and Jiangsu provinces had a strong influence on the overall rain chemistry at Huangshan Mountain. The rainwater with influencing air masses from Inner Mongolia was heavily polluted by anthropogenic pollutants.

A Review of Geothermal Type-Curves with Damage Effect: A Case of Practical Apply to a Mexican Geothermal Field

A review of the art state was developed about the inflow relationships and their application for reservoir characterization. The theoretical development of the methodology for determining the damage effect using type-curves of the inflow relationships was shown. We show the process followed for achieve the geothermal type-curve affected with damage for reservoirs with mean salinities of 30000 ppm and temperatures up to 350℃. This type-curve was applied using measurement production data in a Mexican geothermal field. According with the obtained results is shown that the methodology for determining the damage effect using production measurements is a sure alternative for the damage effect calculation. It was used an alternative methodology in order to validate the damage presence and the obtained results were consistent. Last thing shows that both methodologies can be combined as a confident manner.

找回群众与双向赋能:党建引领乡村治理有效的韧性机制——基于C村美丽屋场建设的个案考察

治理有效是党建引领乡村治理的基本目标。本文从群众路线视角出发,对C村“党建引领美丽屋场建设”实践探索进行剖析,探讨党建引领与乡村治理有效之间的机制。党建引领乡村治理的实践路径在于,通过群众动员和组织建构两种策略,在过程层面促进党领共治的治理行动生成,在结构层面实现党领共治的治理网络重塑。党建引领乡村治理的关键要素在于,以政党力量融入为牵引、以群众路线回归为主线,实现农民群众主体性回归和村民自治的职能归位,进而以“政治引领自治、行政助推自治”的双向赋能,充分激活乡村社会自主治理效能,持续形塑乡村治理有效的韧性机制。

构建智慧型群众体育运动的实践研究

开展智慧型群众体育运动,能够推动群众体育运动发展更为科学化、高效化、便捷化、智能化。文章从充分提升科学决策能力、有效均衡分配平台资源、多方协同优化服务结构三方面,探讨智慧型群众体育运动的着力点;从“丰富路径,推进智慧型群众体育运动开展”“拓宽平台,夯实智慧型群众体育运动保障”“完善体系,促成智慧型群众体育运动合力”等方面,分析智慧型群众体育运动的落脚点。

身体质量指数联合三酰甘油与高密度脂蛋白胆固醇比值预测2型糖尿病风险

目的利用体检指标中身体质量指数(BMI)和三酰甘油与高密度脂蛋白胆固醇比值(triglyceride to high-density lipoprotein cholesterol,TG/HDL-C)联合预测2型糖尿病(type 2 diabetes mellitus,T2DM)发病风险。方法基于瑞慈医疗集团2010—2016年体检人群的数据库,通过Cox比例风险模型观测不同BMI的人群基线TG/HDL-C对随访期间T2DM风险的影响,并分析TG/HDL-C与BMI是否存在交互作用。结果在随访期间,13685例研究对象中共有315例最终诊断为T2DM。以BMI=24 kg/m^(2)为界,将所有研究对象分成两个亚组。BMI<24 kg/m^(2)的亚组共有8238例研究对象,96例在随访结束时患T2DM,对潜在的混杂因素进行调整后,升高的TG/HDL-C导致T2DM事件的风险较高[HR 95%CI=1.47(1.23,1.74),P<0.001]。与最低五分位数(Q1)相比,升高的TG/HDL-C五分位数(Q2~Q5)T2DM发病率增加[HR 95%CI分别为:0.73(0.28,1.93)、2.75(1.29,5.85)、2.81(1.28,6.20)和3.91(1.51,10.11)]。BMI≥24 kg/m^(2)的亚组共有5447例研究对象,219例在随访结束时患T2DM。在两个亚组中,随着TG/HDL-C的增加,T2DM患病风险均呈非线性增加,这一变化在BMI<24 kg/m^(2)的亚组更为明显。绘制两个亚组TG/HDLC与3年和5年T2DM发病的ROC曲线,在BMI<24 kg/m^(2)的亚组中,ROC曲线下面积分别为0.72和0.77。在BMI≥24 kg/m^(2)的亚组中,ROC曲线下面积则分别为0.55和0.57。结论在BMI<24 kg/m^(2)的人群中,TG/HDL-C的升高提示T2DM患病风险显著增加。

近代翻译文学:教育观念转变的“引擎”

鸦片战争以降,西学翻译和教育变革成为国人呼声最高的两剂救亡药方。对于翻译中伴随的异质性,如何作用于教育转型的进程,进而引领着教育观念的转变,值得寻绎。潮水般涌入华夏大地的泰西文学,促使近代人才观不断位移,各类译著中的西方人物,焕发出别具一格的魅力,为国人树立了一种新型人才“标杆”。西方教育小说中的教师,呈现出与传统中国教师截然不同的面相,成为形塑崭新师生关系的直接资源。在翻译小说的浸染之下,通俗文学逐渐深入人心,并在课堂上下、校园内外枝蔓攀升、花蕊广播。国人的知识结构在翻译文学的影响之下进行重组,中国教育模式得以吐故纳新,新的教育生态也逐渐建构起来。

全面抗战时期中共争取合法地位的斗争述论

全面抗战时期,中共在坚持独立自主发展方针的前提下,通过与国民党谈判、反对国民党制造的磨擦及联合其他抗日党派等途径的斗争,争取自身合法地位。虽然国民党始终不愿也没有从法律层面承认中共合法,但中共在上述斗争中坚持原则的坚定性与策略的灵活性,保障了自身生存发展的空间,在一定程度上获得了事实上的合法地位,成为抗日战争的中流砥柱,对全民族抗战的胜利作出重要贡献,并最终发展为“决定中国命运”的“最强有力的政治力量”。

20世纪五六十年代的临沂稻改及其体现的沂蒙精神

20世纪五六十年代的临沂稻改,是人民群众从吃地瓜干到吃上大米饭的一场种植业革命。为了改变涝洼地区贫穷落后面貌,临沂地区的广大党员干部群众勇于担当,敢于创造,战胜重重困难,彻底治理了涝洼,发展了水利,改种了水稻,使粮食产量连年提高,稻改获得很大成功。在稻改中党和政府把人民利益放在第一位,勇担重担,全心全意为人民,人民群众跟党走,艰苦奋斗,开拓奋进,无私奉献,这是沂蒙精神在社会主义建设时期的生动体现。

《共产主义运动中的“左派”幼稚病》工会思想的生成逻辑、核心意蕴与现实启示

《共产主义运动中的“左派”幼稚病》是列宁的经典文本之一,蕴含着十分丰富的工会思想。这一工会思想的生成植根于马克思恩格斯严密的工会理论,生发于国际及俄国国内工人运动历史的经验总结,成长于对形形色色工会问题争论的现实批判,具有理论、历史和现实三重逻辑。“党直接依靠工会来进行自己的工作”的特殊地位、“工会是共产主义学校”的职能定位、“对工会进行教育和领导”的组织建设构成这一工会思想的核心意蕴。挖掘这一文本的工会思想对当前做好工会工作具有深刻的现实启示:前提基础在于充分认识到工会工作的极端重要性,根本保证在于坚持党对工会工作的集中统一领导,价值彰显在于发挥工会在新时代的教育培训功能。

党建引领城市社区治理有效性的内在逻辑——基于“政党功能—社会参与”的分析框架

厘清党建引领城市社区治理有效性的内在逻辑是提升社区治理效能的前提。以构建党组织领导的社区治理共同体为目标导向,以政党与社会关系为内在依据,通过建构“政党功能—社会参与”的分析框架可以发现,党建引领城市社区治理的有效性取决于政党功能发挥度和社会力量参与度的高低配置状况。两者交叉形成了“放任型”“管控型”“自治型”和“引领型”四种治理模式,分别折射出了政党与社会无涉、政党整合社会、政党赋权社会、政党引领社会的潜藏逻辑。其中,“引领型”是最有效的模式,因为其能发挥政党功能激活社会参与,形成政党主导下的多元共治。为实现这种模式需要从赋权增能强化政党功能、广泛动员促进社会参与、寓党建于治理提升耦合度三个方面发力。深层次看,党建引领城市社区治理的有效性最终指向的是秩序与活力的平衡,党建引领的核心作用就在于解决这个二元性难题。

关系再造:基层党组织引领社区治理共同体的运行逻辑

构建社区治理共同体是国家推进基层治理现代化的重要路径,需要基层党组织发挥坚强的引领作用。基层开展的“共同缔造”或“熟人创建”等治理实践的深层逻辑在于,基层党组织是以“关系”为切入点,探索“关系激活—关系联结—关系治理”的关系再造路径,形成关系联结型治理模式。关系再造需要激活社区的价值要素、组织要素、情感要素、利益要素和制度要素,通过关系联结为社区治理共同体的形成提供治理理念、治理结构、治理信任、治理动能和治理规则。社区治理共同体的运行逻辑在于发挥基层党组织的引领作用推进关系要素的激活生成,组织驱动和制度嵌入推进关系联结的高效运行,情感动员和利益整合推进关系网络的治理修复。

考虑截面规则性的柱状节理岩体变形及强度特性研究

柱状节理岩体的复杂结构使其现场力学参数的确定存在困难,可靠地估计柱状节理岩体强度及变形特性对工程安全至关重要。结合Voronoi图形及3D打印技术制作不规则柱状节理岩体光敏树脂模具,并制备了具有不同倾角的规则及不规则柱状节理岩体试样。基于开展的单轴压缩试验结果,分析不同截面柱状节理岩体的变形及强度特性差异。根据试样最终破坏形态,揭示柱状节理岩体破坏模式及机制。结合已有研究结果,描述节理面材料对柱状节理岩体破坏形态及强度的影响。基于传统节理系数方法,提出了更能反映柱状节理岩体柱体结构特征的修正节理系数方法。采用修正节理系数法建立规则及不规则柱状节理岩体试验结果与现场变形及强度参数间的经验关系,将所提出计算公式应用于白鹤滩水电站工程,预测结果与现场实测值及RMR法(RMR为岩石质量评分指标)、Q法(Q为岩体质量指标)的预测值进行比较。结果表明,对于现场变形和强度参数,所提出的修正节理系数法的预测结果与现场实测结果较为吻合。