Corrosion is one of the main reasons to cause the operation accident of submarine oil and gas transmission pipelines. As the major corrosion pattern in submarine pipelines, the effects of corrosion clusters consisting...Corrosion is one of the main reasons to cause the operation accident of submarine oil and gas transmission pipelines. As the major corrosion pattern in submarine pipelines, the effects of corrosion clusters consisting of the adjacent corrosion defects on failure pressure are investigated through non-linear large-deformation finite element method. Typically, the failure behavior and limit strength of submarine pipeline with axial groove- groove corrosion defect pair exposed to interhal pressure are analyzed. The effects of corrosion depth and axial spacing between a pair of corrosion defects on failure pressure are concluded. An interaction relationship for corrosion defects in pipelines, as well as prediction formulations for assessing the remaining strength of corroded pipelines are proposed. The expressions based on the proposed interaction relationship give more accurate results than the methods used in the existing design guidelines.展开更多
The "integration of informatization and industrialization" is a constant development process. In China, the integration of industrial economy and information economy is an inevitable trend of economy development. Th...The "integration of informatization and industrialization" is a constant development process. In China, the integration of industrial economy and information economy is an inevitable trend of economy development. The social formation of the current industrial society in China will inevitably transform into the social formation of the integration of industrial society and information society. The "integration of informatization and industrialization" provides necessary technology for economic development,which makes the society have an overall change. This paper tries to make a comparison of the basic features of different formations from the historical development process of the era, in order to summarize the basic characteristics of "integration of informatization and industralization" and its interaction relationship with industrial design.展开更多
Starting with the interactive factors of relationship, this paper analyzes the interactive feature of relationship marketing within the marketing framework. Based on the interactive model of relationship marketing, th...Starting with the interactive factors of relationship, this paper analyzes the interactive feature of relationship marketing within the marketing framework. Based on the interactive model of relationship marketing, this paper puts forward suggestions concerning effective interactive management of relationship marketing from the organization.展开更多
Under the new normal economic growth, lack of motivation, structural imbalances in the economy, the shortage of resources, resource utilization inefficiency, environmental damage and other issues have become increasin...Under the new normal economic growth, lack of motivation, structural imbalances in the economy, the shortage of resources, resource utilization inefficiency, environmental damage and other issues have become increasingly prominent, enterprises as the carrier of economy is one of the root of the problem. Research on enterprise innovation and corporate social responsibility issues, it is conducive to the development of enterprise itself and the transformation of Chinese economy. This paper reviewed the research status of relationships between innovation and corporate social responsibility, through comb the aspects of the definitions and evolution of enterprise innovation and social responsibility, also include both the relationship and the new way(responsible innovation) of combination of them, we found the presence of index system is not perfect, and lack of in-depth comprehensive study and opportunities for future research is prospected.展开更多
The cumulative expression of multistage deformation is complex multiperiod fractures,which are commonly seen in tectonic zones.The Middle Triassic Leikoupo Formation in the western Sichuan Basin Depression,China,is a ...The cumulative expression of multistage deformation is complex multiperiod fractures,which are commonly seen in tectonic zones.The Middle Triassic Leikoupo Formation in the western Sichuan Basin Depression,China,is a typical marine carbonate reservoir with natural fractures caused mainly by tectonic movements.According to outcrops,drill cores,image logging,and fluid inclusions,the fracture characteristics,types of natural fractures,and interactions of fractures are determined.In total,419 natural fractures in 493.2 m of cores from 7 wells are investigated,which are mainly shear and tensile fractures with a small number of weathering generated fractures.Meanwhile,the results of the stable isotope analysis of δ13C and δ18O,as well as the flow fluid inclusion data,reveal four tectonic periods of fractures with different occurrences.Based on the history of regional tectonic evolution,indicating one period of weathering fractures ascribable to stratal uplift and three periods of structural fractures related to the sequential tectonic movements of the Longmenshan fault belt.By analyzing the interaction relationships of fractures,three types of fracture interaction relationships are observed:cutting,restraining,and overlapping.The four stages fractures are chronologically assigned to(1)the early Indosinian N-S trending compression,(2)the late Indosinian NW-SE compression,(3)the middle Yanshanian NE-SE compression,and(4)the early Himalayan E-W compression.The influence of natural fractures on gas migration and well production in marine carbonates is discussed,and indicates that tectonic fractures could provide seepage channels for gas migration and accumulation from near or distant hydrocarbon source rocks into the Middle Triassic Leikoupo Formation.This study utilizes a pragmatic approach for understanding the fracture genesis mechanism in oil and gas field with multiperiod fractures.展开更多
Objectively, a complex interactive coercing relationship exists between urbanization and eco-environment, and the research of this relationship is primarily divided into three schools, i.e., interactive coercion theor...Objectively, a complex interactive coercing relationship exists between urbanization and eco-environment, and the research of this relationship is primarily divided into three schools, i.e., interactive coercion theory, interactive promotion theory and coupling symbiosis theory. Harmonizing the relationship between urbanization and eco-environment is not only an important proposition for the national development plan but also the only way to promote healthy urbanization. Based on an analysis of urbanization process and its relationship with the eco-environment, this article analyzes interactive coercing effects between urbanization and eco-environment from three perspectives of population urbanization, economic urbanization and spatial urbanization, respectively, and analyzes risk effects of the interactive coercion. Further, it shows six basic laws followed by interactive coercion between urbanization and eco-environment, namely, coupling fission law, dynamic hierarchy law, stochastic fluctuation law, non-linear synergetic law, threshold value law and forewarning law, and divides the interactive coercing process into five stages, namely, low-level coordinate, antagonistic, break-in, ameliorative and high-grade coordinate. Based on the geometric derivation, the interactive coercing relationship between urbanization and eco-environment is judged to be non-linear and it can be explained by a double-exponential function formed by the combination of power and exponential functions. Then, the evolutionary types of the interactive coercing relationship are divided into nine ones: rudimentary coordinating, ecology-dominated, synchronal coordinating, urbanization lagging, stepwise break-in, exorbitant urbanization, fragile ecology, rudimentary break-in and unsustainable types. Finally, based on an interactive coercion model, the degree of interactive coercion can be examined, and then, an evolutionary cycle can be divided into four phases, namely rudimentary symbiosis, harmonious development, utmost increasing and spiral type rising. The study results offer a scientific decision-making of healthy urbanization for achieving the goal of eco-environment protection and promoting urbanization.展开更多
In polymer modified cementitious materials, it is hard to set up a chemical connection between the added polymer and the cement moiety. In this study FS (functional silane) was adopted to form this connection as a b...In polymer modified cementitious materials, it is hard to set up a chemical connection between the added polymer and the cement moiety. In this study FS (functional silane) was adopted to form this connection as a bridge component which has the functional group forming bonds with polymer. To testify the connection between FS and cement moiety, Q2/Q1 ratio (Qx: intensity ratio) investigation was carried out by the means of quantitative solid state 29Si MAS NMR. The results show that the Q2/Q1 ratio has increased with the addition of FS which indicates that the silicon chain length has increased, and the quantity of silicon atoms at site of Q2, chain site, has enhanced, showing that the silicon atom of FS has connected to the silicon chain of cement moiety by the bond "-Si-O-Si-" formation.展开更多
In the past decade,the p53-MDM2 protein-protein interaction by small molecules has been confirmed as a successful strategy for cancer therapy.In our previous work,pyrrolo[3,4-c]pyrazol-6(1H)-ones were found to be po...In the past decade,the p53-MDM2 protein-protein interaction by small molecules has been confirmed as a successful strategy for cancer therapy.In our previous work,pyrrolo[3,4-c]pyrazol-6(1H)-ones were found to be potent p53-MDM2 inhibitors.Further optimization and structure-activity relationship studies were described in the present work.The result revealed that benzyl group on position N1 of imidazole and bromine on C4-phenyl of pyrrolidone showed higher inhibitory activities.In vitro antiproliferative assay demonstrated the potent p53-MDM2 inhibitor 5c with 4-fold selectivity for U2 OS and Saos-2 cells.These data indicated that 4,5-dihydropyrrolo[3,4-c]pyrazol-6(1H)-one moiety is a valuable scaffold for further development of p53-MDM2 inhibitors.展开更多
In theory,there is a close interactive relationship between urbanization and motorization. This paper investigates the interactive relationship between urbanization and motorization in China after its reform and openi...In theory,there is a close interactive relationship between urbanization and motorization. This paper investigates the interactive relationship between urbanization and motorization in China after its reform and opening-up by using the urbanization and motorization data during the period 1985 – 2010. The research fi nds that during the period 1985 – 2000,there indeed was a long-run stable interactive relationship between urbanization and motorization in China. It proves that motorization has a time lagged impact on urbanization,whereas urbanization alone has less effect on motorization growth than the infl uence of motorization growth on the rapid growth of urbanization.展开更多
The unified management and planning of national or provincial natural resources distributed both aboveground and underground have become increasingly important.Accurate depictions of natural resource elements and thei...The unified management and planning of national or provincial natural resources distributed both aboveground and underground have become increasingly important.Accurate depictions of natural resource elements and their interactions are key to achieving integrated and systematic management of natural resources.However,current spatiotemporal data models are based only on data descriptions,attribute records,and other model knowledge of a more general basis,without intuitively describing relationships between these elements and natural resources.This paper,therefore,proposes an integrated data-model-knowledge representation model to explicitly describe the time,space,and interaction of natural resource entities through an integrated knowledge graph.First,this study constructs a conceptual model using the aspects of semantics,scale,and data-model-knowledge,thereby explicitly describing the relationships of natural resources.Second,a logical model of natural resource representation is proposed,that is integrated with time,space,attributes,and relationships.Finally,taking the management of water resources as an example,this paper realizes the meticulous presentation of the levels of detail and rich semantic relations of natural resource entities.The findings of this study lay the foundation for a more efficient,precise,and lucid perception of the distribution laws and complicated interactional relationships of natural resources,both aboveground and underground.展开更多
基金the National Natural Science Foundation of China (GrantNo.50439010)the Ministry of Education of China (Grant No.305003)
文摘Corrosion is one of the main reasons to cause the operation accident of submarine oil and gas transmission pipelines. As the major corrosion pattern in submarine pipelines, the effects of corrosion clusters consisting of the adjacent corrosion defects on failure pressure are investigated through non-linear large-deformation finite element method. Typically, the failure behavior and limit strength of submarine pipeline with axial groove- groove corrosion defect pair exposed to interhal pressure are analyzed. The effects of corrosion depth and axial spacing between a pair of corrosion defects on failure pressure are concluded. An interaction relationship for corrosion defects in pipelines, as well as prediction formulations for assessing the remaining strength of corroded pipelines are proposed. The expressions based on the proposed interaction relationship give more accurate results than the methods used in the existing design guidelines.
文摘The "integration of informatization and industrialization" is a constant development process. In China, the integration of industrial economy and information economy is an inevitable trend of economy development. The social formation of the current industrial society in China will inevitably transform into the social formation of the integration of industrial society and information society. The "integration of informatization and industrialization" provides necessary technology for economic development,which makes the society have an overall change. This paper tries to make a comparison of the basic features of different formations from the historical development process of the era, in order to summarize the basic characteristics of "integration of informatization and industralization" and its interaction relationship with industrial design.
文摘Starting with the interactive factors of relationship, this paper analyzes the interactive feature of relationship marketing within the marketing framework. Based on the interactive model of relationship marketing, this paper puts forward suggestions concerning effective interactive management of relationship marketing from the organization.
基金supported by the 2016 graduate research project of Guizhou University of Finance and Economics: "Enterprise Innovation, Social Responsibility: Interaction Mechanism and Empirical Test"
文摘Under the new normal economic growth, lack of motivation, structural imbalances in the economy, the shortage of resources, resource utilization inefficiency, environmental damage and other issues have become increasingly prominent, enterprises as the carrier of economy is one of the root of the problem. Research on enterprise innovation and corporate social responsibility issues, it is conducive to the development of enterprise itself and the transformation of Chinese economy. This paper reviewed the research status of relationships between innovation and corporate social responsibility, through comb the aspects of the definitions and evolution of enterprise innovation and social responsibility, also include both the relationship and the new way(responsible innovation) of combination of them, we found the presence of index system is not perfect, and lack of in-depth comprehensive study and opportunities for future research is prospected.
基金The first,second,and fifth authors acknowledge the financial support provided by the National Natural Science Foundation of China(41672133)The second author also acknowledges the National Natural Science Foundation of China(4207021285).
文摘The cumulative expression of multistage deformation is complex multiperiod fractures,which are commonly seen in tectonic zones.The Middle Triassic Leikoupo Formation in the western Sichuan Basin Depression,China,is a typical marine carbonate reservoir with natural fractures caused mainly by tectonic movements.According to outcrops,drill cores,image logging,and fluid inclusions,the fracture characteristics,types of natural fractures,and interactions of fractures are determined.In total,419 natural fractures in 493.2 m of cores from 7 wells are investigated,which are mainly shear and tensile fractures with a small number of weathering generated fractures.Meanwhile,the results of the stable isotope analysis of δ13C and δ18O,as well as the flow fluid inclusion data,reveal four tectonic periods of fractures with different occurrences.Based on the history of regional tectonic evolution,indicating one period of weathering fractures ascribable to stratal uplift and three periods of structural fractures related to the sequential tectonic movements of the Longmenshan fault belt.By analyzing the interaction relationships of fractures,three types of fracture interaction relationships are observed:cutting,restraining,and overlapping.The four stages fractures are chronologically assigned to(1)the early Indosinian N-S trending compression,(2)the late Indosinian NW-SE compression,(3)the middle Yanshanian NE-SE compression,and(4)the early Himalayan E-W compression.The influence of natural fractures on gas migration and well production in marine carbonates is discussed,and indicates that tectonic fractures could provide seepage channels for gas migration and accumulation from near or distant hydrocarbon source rocks into the Middle Triassic Leikoupo Formation.This study utilizes a pragmatic approach for understanding the fracture genesis mechanism in oil and gas field with multiperiod fractures.
基金Under the auspices of Key Project of National Natural Science Foundation of China (No. 40335049),National Natural Science Foundation of China (No. 40971101)
文摘Objectively, a complex interactive coercing relationship exists between urbanization and eco-environment, and the research of this relationship is primarily divided into three schools, i.e., interactive coercion theory, interactive promotion theory and coupling symbiosis theory. Harmonizing the relationship between urbanization and eco-environment is not only an important proposition for the national development plan but also the only way to promote healthy urbanization. Based on an analysis of urbanization process and its relationship with the eco-environment, this article analyzes interactive coercing effects between urbanization and eco-environment from three perspectives of population urbanization, economic urbanization and spatial urbanization, respectively, and analyzes risk effects of the interactive coercion. Further, it shows six basic laws followed by interactive coercion between urbanization and eco-environment, namely, coupling fission law, dynamic hierarchy law, stochastic fluctuation law, non-linear synergetic law, threshold value law and forewarning law, and divides the interactive coercing process into five stages, namely, low-level coordinate, antagonistic, break-in, ameliorative and high-grade coordinate. Based on the geometric derivation, the interactive coercing relationship between urbanization and eco-environment is judged to be non-linear and it can be explained by a double-exponential function formed by the combination of power and exponential functions. Then, the evolutionary types of the interactive coercing relationship are divided into nine ones: rudimentary coordinating, ecology-dominated, synchronal coordinating, urbanization lagging, stepwise break-in, exorbitant urbanization, fragile ecology, rudimentary break-in and unsustainable types. Finally, based on an interactive coercion model, the degree of interactive coercion can be examined, and then, an evolutionary cycle can be divided into four phases, namely rudimentary symbiosis, harmonious development, utmost increasing and spiral type rising. The study results offer a scientific decision-making of healthy urbanization for achieving the goal of eco-environment protection and promoting urbanization.
基金Funded by the National Basic Research Program of China(973 Program(No.2009CB6232007)
文摘In polymer modified cementitious materials, it is hard to set up a chemical connection between the added polymer and the cement moiety. In this study FS (functional silane) was adopted to form this connection as a bridge component which has the functional group forming bonds with polymer. To testify the connection between FS and cement moiety, Q2/Q1 ratio (Qx: intensity ratio) investigation was carried out by the means of quantitative solid state 29Si MAS NMR. The results show that the Q2/Q1 ratio has increased with the addition of FS which indicates that the silicon chain length has increased, and the quantity of silicon atoms at site of Q2, chain site, has enhanced, showing that the silicon atom of FS has connected to the silicon chain of cement moiety by the bond "-Si-O-Si-" formation.
基金supported in part by the National Natural Science Foundation of China (Nos. 81373331 and 81502978)the Bio-Pharmaceutical Project of Science and Technology of Shanghai (No. 14431902300)Youth grant of Second Military Medical University (No. 2014QN08)
文摘In the past decade,the p53-MDM2 protein-protein interaction by small molecules has been confirmed as a successful strategy for cancer therapy.In our previous work,pyrrolo[3,4-c]pyrazol-6(1H)-ones were found to be potent p53-MDM2 inhibitors.Further optimization and structure-activity relationship studies were described in the present work.The result revealed that benzyl group on position N1 of imidazole and bromine on C4-phenyl of pyrrolidone showed higher inhibitory activities.In vitro antiproliferative assay demonstrated the potent p53-MDM2 inhibitor 5c with 4-fold selectivity for U2 OS and Saos-2 cells.These data indicated that 4,5-dihydropyrrolo[3,4-c]pyrazol-6(1H)-one moiety is a valuable scaffold for further development of p53-MDM2 inhibitors.
基金supported by the National Science Foundation of China(Grant 51008002)the State Key Laboratory of Subtropical Building Science South China University of Technology(Grant 2011KB20)+1 种基金the Research Fund of Harbin Institute of Technology(Grant HIT.NSRIF.2013100 and HIT.NSFIR.2011126)the Peking University–Lincoln Institute Center for Urban Development and Land Policy(DS20120901).
文摘In theory,there is a close interactive relationship between urbanization and motorization. This paper investigates the interactive relationship between urbanization and motorization in China after its reform and opening-up by using the urbanization and motorization data during the period 1985 – 2010. The research fi nds that during the period 1985 – 2000,there indeed was a long-run stable interactive relationship between urbanization and motorization in China. It proves that motorization has a time lagged impact on urbanization,whereas urbanization alone has less effect on motorization growth than the infl uence of motorization growth on the rapid growth of urbanization.
基金supported by the National Natural Science Foundation of China[Projects No.41871314,4187010232]the Program of the Department of Natural Resources of Sichuan Province[Grant Number KJ20206].
文摘The unified management and planning of national or provincial natural resources distributed both aboveground and underground have become increasingly important.Accurate depictions of natural resource elements and their interactions are key to achieving integrated and systematic management of natural resources.However,current spatiotemporal data models are based only on data descriptions,attribute records,and other model knowledge of a more general basis,without intuitively describing relationships between these elements and natural resources.This paper,therefore,proposes an integrated data-model-knowledge representation model to explicitly describe the time,space,and interaction of natural resource entities through an integrated knowledge graph.First,this study constructs a conceptual model using the aspects of semantics,scale,and data-model-knowledge,thereby explicitly describing the relationships of natural resources.Second,a logical model of natural resource representation is proposed,that is integrated with time,space,attributes,and relationships.Finally,taking the management of water resources as an example,this paper realizes the meticulous presentation of the levels of detail and rich semantic relations of natural resource entities.The findings of this study lay the foundation for a more efficient,precise,and lucid perception of the distribution laws and complicated interactional relationships of natural resources,both aboveground and underground.