Objective: To evaluate the therapeutic effect of Juanxiao Tablet (JXT) in treating asthma. Methods: Clinical observation on 447 cases of asthma was done in double- or single-blinded control method, and the therapeutic...Objective: To evaluate the therapeutic effect of Juanxiao Tablet (JXT) in treating asthma. Methods: Clinical observation on 447 cases of asthma was done in double- or single-blinded control method, and the therapeutic effect and safety of JXT were analysed. The effect of JXT in anti-asthma, expectorant, antisepsis, hypoxia tolerance was studied, and its acute and chronic toxicity was also examined. Results: The clinical control rate in patients treated with JXT was 38.2%, the markedly effective rate 31.2% and the total effective rate 93.4%, whereas in patients treated with Oleum Vitex Negundo, the respective rates were 13.3%, 20.0% and 68.5%. Results of pulmonary function and IgE measurement were consistent with clinical effect. Experimental study showed that JXT has the actions of anti-asthma, expectorant, antisepsis and hypoxia tolerance enhancement, with its LD50 (40.48±5.17) g/kg. Conclusion: JXT is a new Chinese herbal preparation of good effect, with less toxic-side effect for asthma treatment.展开更多
文摘Objective: To evaluate the therapeutic effect of Juanxiao Tablet (JXT) in treating asthma. Methods: Clinical observation on 447 cases of asthma was done in double- or single-blinded control method, and the therapeutic effect and safety of JXT were analysed. The effect of JXT in anti-asthma, expectorant, antisepsis, hypoxia tolerance was studied, and its acute and chronic toxicity was also examined. Results: The clinical control rate in patients treated with JXT was 38.2%, the markedly effective rate 31.2% and the total effective rate 93.4%, whereas in patients treated with Oleum Vitex Negundo, the respective rates were 13.3%, 20.0% and 68.5%. Results of pulmonary function and IgE measurement were consistent with clinical effect. Experimental study showed that JXT has the actions of anti-asthma, expectorant, antisepsis and hypoxia tolerance enhancement, with its LD50 (40.48±5.17) g/kg. Conclusion: JXT is a new Chinese herbal preparation of good effect, with less toxic-side effect for asthma treatment.
