Firstly, physical and chemical properties of dust removed from BOF gas are analyzed, and then the cold banding technology of dust removed from BOF gas and its application are introduced. Tests have proved that using c...Firstly, physical and chemical properties of dust removed from BOF gas are analyzed, and then the cold banding technology of dust removed from BOF gas and its application are introduced. Tests have proved that using cooled agglomerated pellets made of the dust removed from BOF gas and small amounts of modified starch as a coolant and slagging agent in steel production can bring about considerable economic, social and environmental benefits.展开更多
This paper presents a model derived for quantitative evaluation and prediction of the concentration of phosphorus removed during pyro-hydro beneficiation of iron oxide ore. Potassium hydroxide was used as the leaching...This paper presents a model derived for quantitative evaluation and prediction of the concentration of phosphorus removed during pyro-hydro beneficiation of iron oxide ore. Potassium hydroxide was used as the leaching solution and the reaction vessel containing the solution and ore was heated at a temperature of 600℃ for 10 minutes. The results of the investigation indicates that the model;P = (e0.7827) S predicts the concentration of phosphorus removed, based on the concentration of sulphur simultaneously removed. It was observed that the validity of the model is rooted in the expression lnP = lnN + lnS where both sides of the expression are approximately equal to 4. The maximum deviation of the model-predicted concentration of removed phosphorus from the corresponding concentration obtained from the experiment was less than 3%. The concentrations of phosphorus removed per unit mass-input of iron oxide ore as obtained from experiment and derived model are 0.8917 and 1.0354 mg/kg g-1 respectively. Similarly, the concentrations of phosphorus removed per unit concentration of removed sulphur as obtained from experiment and derived model are 1.8838 and 2.1874 mg/kg (mg/kg)-1 respectively. This implies that the concentration of phosphorus removed is approximately equal to the concentration of simultaneously removed sulphur during the beneficiation process.展开更多
One year has passed since the revised Law on the Protection of the Rights and Interests of Consumers came into effect on March 15, 2014, the World Consumer Rights Day. Following the changes, consumers can return goods...One year has passed since the revised Law on the Protection of the Rights and Interests of Consumers came into effect on March 15, 2014, the World Consumer Rights Day. Following the changes, consumers can return goods they are dissatisfied with and get an unconditional refund within seven days of purchase. This applies to not only Internet shopping but also TV- and telephone-based sales.展开更多
An enclosed cyclone passageway(ECP)dust-collecting fan is discussed.The ECP fan separates dust by centrifugal force originating from a driven spiral airflow,and its design takes the constraints of Chinese underground ...An enclosed cyclone passageway(ECP)dust-collecting fan is discussed.The ECP fan separates dust by centrifugal force originating from a driven spiral airflow,and its design takes the constraints of Chinese underground coal mines into consideration.Using the force equilibrium law,a general equation for dust removal in the centrifugal dust removal section(CDRS)of the ECP fan is deduced.This general equation is simplified using the CDRS structure and the fan operating parameters and is analysed numerically.The attractive results show that increases in the airflow rate of the fan,the structural ratio of the ECPs and the radius of the extended axis can improve the dust removal performance of the CDRS.Furthermore,the effects of the structural ratio and the radius on dust removal dominate over that of the flow rate,and the effect of the structural ratio is more significant than that of the radius.展开更多
Quantifying and mapping heavy metals’ concentrations in the soil are important in monitoring and managing heavy metal pollution in the mining areas. However, the cover on the soil acts as a balk when retrieving infor...Quantifying and mapping heavy metals’ concentrations in the soil are important in monitoring and managing heavy metal pollution in the mining areas. However, the cover on the soil acts as a balk when retrieving information from soil. In order to retrieve heavy metal pollution precisely and quickly from hyperspectral images, this study presents a new method to remove non-soil information based NDVI from hyper-spectral and multi-spectral images. The method assumed that the mixed objects in each pixel of remote sensing images are composed only of soil and vegetation-based non-soil end-generational endmembers, then, the soil information of each pixel can be compensated with the non-soil information removed based on its NDVI. Thus, the soil DN value can be corrected to retrieve soil information more precisely. The method has been used on the Hyperion image in June 8, 2002 and the Gaofen-2 (GF-2) image in February 14, 2016 to retrieve the heavy metals’ contents in Bai-ma and De-sheng mining areas, Miyi County, Sichuan Province. From the non-soil information removed images, the R2 and RMSE of the models of estimating Cr, Ag, Cu and Ba in soil are 0.68, 0.724, 0.71, 0.695 and 75.96, 0.03, 52.88, 284.70 respectively. From the original images, the R2 and RMSE of the models of estimating Cr, Ag, Cu and Ba in soil are 0.67, 0.385, 0.425, 0.406 and 80.11, 0.18, 53.43, 396.49 respectively. The retrieval results show that the non-soil information removed images are superior to original images in soil heavy metals’ contents retrieval. This indicates that this method is feasible, and it can be used in soil information retrieval.展开更多
In the Acknowledgments Section,please replace“Shell oil”for“TotalEnergies”.The authors would like to apologise for any inconvenience caused.For the sake of clarity(“Shell oil”should be removed and in boldblack“...In the Acknowledgments Section,please replace“Shell oil”for“TotalEnergies”.The authors would like to apologise for any inconvenience caused.For the sake of clarity(“Shell oil”should be removed and in boldblack“TotalEnergies”inserted),this section should say:The authors would like to thank Moura Batteries for the financial support.展开更多
China launched a recommendation for the protection and return of cultural objects removed from colonial contexts or acquired by other unjustifiable or unethical means,winning a big applause from many countries which a...China launched a recommendation for the protection and return of cultural objects removed from colonial contexts or acquired by other unjustifiable or unethical means,winning a big applause from many countries which are seeking for more cooperation in solving this serious problem.展开更多
Following publication of the original article[1],the authors reported that the author Hun-Gi Jung should be affiliated as 3,4 and 5 instead of 4 and 5.The author’s name“A.-Yeon Kim”needed to be updated to“A-Yeon ...Following publication of the original article[1],the authors reported that the author Hun-Gi Jung should be affiliated as 3,4 and 5 instead of 4 and 5.The author’s name“A.-Yeon Kim”needed to be updated to“A-Yeon Kim”,removing the period.The correct author’s name and affiliation have been provided in this Correction.The original article[1]has been corrected.展开更多
Global images of auroras obtained by cameras on spacecraft are a key tool for studying the near-Earth environment.However,the cameras are sensitive not only to auroral emissions produced by precipitating particles,but...Global images of auroras obtained by cameras on spacecraft are a key tool for studying the near-Earth environment.However,the cameras are sensitive not only to auroral emissions produced by precipitating particles,but also to dayglow emissions produced by photoelectrons induced by sunlight.Nightglow emissions and scattered sunlight can contribute to the background signal.To fully utilize such images in space science,background contamination must be removed to isolate the auroral signal.Here we outline a data-driven approach to modeling the background intensity in multiple images by formulating linear inverse problems based on B-splines and spherical harmonics.The approach is robust,flexible,and iteratively deselects outliers,such as auroral emissions.The final model is smooth across the terminator and accounts for slow temporal variations and large-scale asymmetries in the dayglow.We demonstrate the model by using the three far ultraviolet cameras on the Imager for Magnetopause-to-Aurora Global Exploration(IMAGE)mission.The method can be applied to historical missions and is relevant for upcoming missions,such as the Solar wind Magnetosphere Ionosphere Link Explorer(SMILE)mission.展开更多
BACKGROUND Choosing an optimal post-polypectomy management strategy of malignant colorectal polyps is challenging,and evidence regarding a surveillance-only strategy is limited.AIM To evaluate long-term outcomes after...BACKGROUND Choosing an optimal post-polypectomy management strategy of malignant colorectal polyps is challenging,and evidence regarding a surveillance-only strategy is limited.AIM To evaluate long-term outcomes after endoscopic removal of malignant colorectal polyps.METHODS A single-center retrospective cohort study was conducted to evaluate outcomes after endoscopic removal of malignant colorectal polyps between 2010 and 2020.Residual disease rate and nodal metastases after secondary surgery and local and distant recurrence rate for those with at least 1 year of follow-up were invest-igated.Event rates for categorical variables and means for continuous variables with 95%confidence intervals were calculated,and Fisher’s exact test and Mann-Whitney test were performed.Potential risk factors of adverse outcomes were RESULTS In total,135 lesions(mean size:22.1 mm;location:42%rectal)from 129 patients(mean age:67.7 years;56%male)were enrolled.The proportion of pedunculated and non-pedunculated lesions was similar,with en bloc resection in 82%and 47%of lesions,respectively.Tumor differentiation,distance from resection margins,depth of submucosal invasion,lymphovascular invasion,and budding were reported at 89.6%,45.2%,58.5%,31.9%,and 25.2%,respectively.Residual tumor was found in 10 patients,and nodal metastasis was found in 4 of 41 patients who underwent secondary surgical resection.Univariate analysis identified piecemeal resection as a risk factor for residual malignancy(odds ratio:1.74;P=0.042).At least 1 year of follow-up was available for 117 lesions from 111 patients(mean follow-up period:5.59 years).Overall,54%,30%,30%,11%,and 16%of patients presented at the 1-year,3-year,5-year,7-year,and 9-10-year surveillance examinations.Adverse outcomes occurred in 9.0%(local recurrence and dissemination in 4 patients and 9 patients,respectively),with no difference between patients undergoing secondary surgery and surveillance only.CONCLUSION Reporting of histological features and adherence to surveillance colonoscopy needs improvement.Long-term adverse outcome rates might be higher than previously reported,irrespective of whether secondary surgery was performed.展开更多
Elucidating the complex interactions between the work material and abrasives during grinding of gallium nitride(GaN)single crystals is an active and challenging research area.In this study,molecular dynamics simulatio...Elucidating the complex interactions between the work material and abrasives during grinding of gallium nitride(GaN)single crystals is an active and challenging research area.In this study,molecular dynamics simulations were performed on double-grits interacted grinding of GaN crystals;and the grinding force,coefficient of friction,stress distribution,plastic damage behaviors,and abrasive damage were systematically investigated.The results demonstrated that the interacted distance in both radial and transverse directions achieved better grinding quality than that in only one direction.The grinding force,grinding induced stress,subsurface damage depth,and abrasive wear increase as the transverse interacted distance increases.However,there was no clear correlation between the interaction distance and the number of atoms in the phase transition and dislocation length.Appropriate interacted distances between abrasives can decrease grinding force,coefficient of friction,grinding induced stress,subsurface damage depth,and abrasive wear during the grinding process.The results of grinding tests combined with cross-sectional transmission electron micrographs validated the simulated damage results,i.e.amorphous atoms,high-pressure phase transition,dislocations,stacking faults,and lattice distortions.The results of this study will deepen our understanding of damage accumulation and material removal resulting from coupling between abrasives during grinding and can be used to develop a feasible approach to the wheel design of ordered abrasives.展开更多
Photocatalysis offers a sustainable means for the oxidative removal of low concentrations of NOx(NO,NO2,N2O,N2O5,etc.)from the atmosphere.Layered double hydroxides(LDHs)are promising candidate photocatalysts owing to ...Photocatalysis offers a sustainable means for the oxidative removal of low concentrations of NOx(NO,NO2,N2O,N2O5,etc.)from the atmosphere.Layered double hydroxides(LDHs)are promising candidate photocatalysts owing to their unique layered and tunable chemical structures and abundant surface hydroxide(OH)moieties,which are hydroxyl radical(OH)precursors.However,the practical applications of LDHs are limited by their poor charge-separation ability and insufficient active sites.Herein,we developed a facile N_(2)H_(4)-driven etching approach to introduce dual Ni^(2+)and OHvacancies(Niv and OHv,respectively)into NiFe-LDH nanosheets(hereafter referred to as NiFe-LDH-et)to facilitate improved charge-carrier separation and active Lewis acidic site(Fe^(3+)and Ni^(2+)exposed at OHv)formation.In contrast to inert pristine LDH,NiFe-LDH-et actively removed NO under visible-light illumination.Specifically,Ni_(76)Fe_(24)-LDH-et etched with 1.50 mmol·L^(-1)N_(2)H_(4)solution removed 32.8%of the NO in continuously flowing air(NO feed concentration:500 parts per billion(ppb))under visible-light illumination,thereby outperforming most reported catalysts.Experimental and theoretical data revealed that the dual vacancies promoted the production of reactive oxygen species(O_(2)·^(-)andOH)and the adsorption of NO on the LDH.In situ spectroscopy demonstrated that NO was preferentially adsorbed at Lewis acidic sites,particularly exposed Fe^(3+)sites,converted into NO+,and subsequently oxidized to NO3without the notable formation of the more toxic intermediate NO2,thereby alleviating risks associated with its production and emission.展开更多
Dust removal from pyrolytic vapors at high temperatures is an obstacle to the industrialization of the coal pyrolysis process.In this work,a granular bed with expanded perlites as filtration media was designed and int...Dust removal from pyrolytic vapors at high temperatures is an obstacle to the industrialization of the coal pyrolysis process.In this work,a granular bed with expanded perlites as filtration media was designed and integrated into a 10 t·d^(–1)coal pyrolysis facility.The testing results showed that around 97.56%dust collection efficiency was achieved.As a result,dust content in tar was significantly lowered.The pressure drop of the granular bed maintained in the range of 356 Pa to 489 Pa.The dust size in the effluent after filtration exhibited a bimodal distribution,which was attributed to the heterogeneity of the dust components.The effects of filtration bed on pyrolytic product yields were also discussed.A modified filtration model based on the macroscopic phenomenological theory was proposed to describe the performance of the granular bed.The computation results were well agreed with the experimental data.展开更多
Lysosomes are discrete organelles that act as recycling centers for extracellular and intracellular materials,playing a pivotal role in maintaining cellular homeostasis.Their acidic environment,maintained by numerous ...Lysosomes are discrete organelles that act as recycling centers for extracellular and intracellular materials,playing a pivotal role in maintaining cellular homeostasis.Their acidic environment,maintained by numerous hydrolytic enzymes,facilitates substrate degradation.Dysfunction in lysosomal processes can lead to abnormal substrate degradation,significantly impacting cellular homeostasis.High energy-demanding cells,such as post-mitotic neurons,are especially vulnerable to these changes,often resulting in neurological diseases.Autophagy,a conserved catabolic process,requires extensive lysosomal utilization.It plays a key role in removing unnecessary intracellular components,ensuring cellular homeostasis,and promoting cell survival during stress conditions such as starvation,infection,or cellular damage.展开更多
For decades,researchers have known that when neurons lose their activating inputs,they can atrophy and even die.For example,removing sensory nerve inputs from the arm to the spinal cord after amputation or cutting the...For decades,researchers have known that when neurons lose their activating inputs,they can atrophy and even die.For example,removing sensory nerve inputs from the arm to the spinal cord after amputation or cutting the spinal nerves can shrink the post-synaptic target zones(e.g.,Woods et al.,2000).From touch receptors for the hand and arm,primary nerve afferents enter the spinal cord,and axons travel in the dorsal columns to target the cuneate nucleus(Cu)of the brainstem on the same side of the body(Figure 1).When sensory loss is unilateral,the overwhelming result is for the associated primary target zone to shrink in total size(cross-sectional area),as compared to the size of the opposite side.展开更多
Methicillin-resistant Staphylococcus aureus(MRSA)is a common pathogen causing acquired infections.Antibiotics are routinely employed for bacterial infection treatment.Excessive antibiotic use for bacterial infections ...Methicillin-resistant Staphylococcus aureus(MRSA)is a common pathogen causing acquired infections.Antibiotics are routinely employed for bacterial infection treatment.Excessive antibiotic use for bacterial infections heightens resistance,and MRSA resistance is being prevalent[1].MRSA exhibits substantial resistance to conventional antibiotics,which is associated with its biofilm-forming capability.The bacterial biofilm serves as a barrier,restricting nutrient access and slowing internal metabolism,increasing antibiotic resistance.The bacterial biofilm forms a defensive layer,resisting antibiotic penetration while preventing nutrient entry,inducing a slow bacterial metabolism,and increasing bacterial resistance[2].Consequently,biofilm formation and the emergence of resistance to conventional antibiotics have become substantial challenges in the field of infectious diseases.The development of agents to remove biofilm barriers is urgently required because biofilms are extremely hazardous.展开更多
In the manufacturing of biotechnology drug products,the viral safety control strategy is a critical pharmaceutical quality management framework that contains three key elements:prevention,testing,and clearance.The pre...In the manufacturing of biotechnology drug products,the viral safety control strategy is a critical pharmaceutical quality management framework that contains three key elements:prevention,testing,and clearance.The prevention strategy involves rigorous screening for any adventitious virus contamination in the raw materials,reagents,and endogenous/adventitious virus contamination in the cell banks.展开更多
文摘Firstly, physical and chemical properties of dust removed from BOF gas are analyzed, and then the cold banding technology of dust removed from BOF gas and its application are introduced. Tests have proved that using cooled agglomerated pellets made of the dust removed from BOF gas and small amounts of modified starch as a coolant and slagging agent in steel production can bring about considerable economic, social and environmental benefits.
文摘This paper presents a model derived for quantitative evaluation and prediction of the concentration of phosphorus removed during pyro-hydro beneficiation of iron oxide ore. Potassium hydroxide was used as the leaching solution and the reaction vessel containing the solution and ore was heated at a temperature of 600℃ for 10 minutes. The results of the investigation indicates that the model;P = (e0.7827) S predicts the concentration of phosphorus removed, based on the concentration of sulphur simultaneously removed. It was observed that the validity of the model is rooted in the expression lnP = lnN + lnS where both sides of the expression are approximately equal to 4. The maximum deviation of the model-predicted concentration of removed phosphorus from the corresponding concentration obtained from the experiment was less than 3%. The concentrations of phosphorus removed per unit mass-input of iron oxide ore as obtained from experiment and derived model are 0.8917 and 1.0354 mg/kg g-1 respectively. Similarly, the concentrations of phosphorus removed per unit concentration of removed sulphur as obtained from experiment and derived model are 1.8838 and 2.1874 mg/kg (mg/kg)-1 respectively. This implies that the concentration of phosphorus removed is approximately equal to the concentration of simultaneously removed sulphur during the beneficiation process.
文摘One year has passed since the revised Law on the Protection of the Rights and Interests of Consumers came into effect on March 15, 2014, the World Consumer Rights Day. Following the changes, consumers can return goods they are dissatisfied with and get an unconditional refund within seven days of purchase. This applies to not only Internet shopping but also TV- and telephone-based sales.
基金supported by the Natural Science Foundation of China and Shenhua Group Corporation Limited(U1361118)the Hunan Provincial Natural Science Foundation of China(13JJ8016,2015JJ2061)+1 种基金the State Key Laboratory for Geomechanics and Deep Underground Engineering(SKLGDUEK1018)the Project of Scientific Research Fund of Hunan Provincial Education Department(Nos.12C1099,14C0425).
文摘An enclosed cyclone passageway(ECP)dust-collecting fan is discussed.The ECP fan separates dust by centrifugal force originating from a driven spiral airflow,and its design takes the constraints of Chinese underground coal mines into consideration.Using the force equilibrium law,a general equation for dust removal in the centrifugal dust removal section(CDRS)of the ECP fan is deduced.This general equation is simplified using the CDRS structure and the fan operating parameters and is analysed numerically.The attractive results show that increases in the airflow rate of the fan,the structural ratio of the ECPs and the radius of the extended axis can improve the dust removal performance of the CDRS.Furthermore,the effects of the structural ratio and the radius on dust removal dominate over that of the flow rate,and the effect of the structural ratio is more significant than that of the radius.
文摘Quantifying and mapping heavy metals’ concentrations in the soil are important in monitoring and managing heavy metal pollution in the mining areas. However, the cover on the soil acts as a balk when retrieving information from soil. In order to retrieve heavy metal pollution precisely and quickly from hyperspectral images, this study presents a new method to remove non-soil information based NDVI from hyper-spectral and multi-spectral images. The method assumed that the mixed objects in each pixel of remote sensing images are composed only of soil and vegetation-based non-soil end-generational endmembers, then, the soil information of each pixel can be compensated with the non-soil information removed based on its NDVI. Thus, the soil DN value can be corrected to retrieve soil information more precisely. The method has been used on the Hyperion image in June 8, 2002 and the Gaofen-2 (GF-2) image in February 14, 2016 to retrieve the heavy metals’ contents in Bai-ma and De-sheng mining areas, Miyi County, Sichuan Province. From the non-soil information removed images, the R2 and RMSE of the models of estimating Cr, Ag, Cu and Ba in soil are 0.68, 0.724, 0.71, 0.695 and 75.96, 0.03, 52.88, 284.70 respectively. From the original images, the R2 and RMSE of the models of estimating Cr, Ag, Cu and Ba in soil are 0.67, 0.385, 0.425, 0.406 and 80.11, 0.18, 53.43, 396.49 respectively. The retrieval results show that the non-soil information removed images are superior to original images in soil heavy metals’ contents retrieval. This indicates that this method is feasible, and it can be used in soil information retrieval.
文摘In the Acknowledgments Section,please replace“Shell oil”for“TotalEnergies”.The authors would like to apologise for any inconvenience caused.For the sake of clarity(“Shell oil”should be removed and in boldblack“TotalEnergies”inserted),this section should say:The authors would like to thank Moura Batteries for the financial support.
文摘China launched a recommendation for the protection and return of cultural objects removed from colonial contexts or acquired by other unjustifiable or unethical means,winning a big applause from many countries which are seeking for more cooperation in solving this serious problem.
文摘Following publication of the original article[1],the authors reported that the author Hun-Gi Jung should be affiliated as 3,4 and 5 instead of 4 and 5.The author’s name“A.-Yeon Kim”needed to be updated to“A-Yeon Kim”,removing the period.The correct author’s name and affiliation have been provided in this Correction.The original article[1]has been corrected.
基金supported by the Research Council of Norway under contracts 223252/F50 and 300844/F50the Trond Mohn Foundation。
文摘Global images of auroras obtained by cameras on spacecraft are a key tool for studying the near-Earth environment.However,the cameras are sensitive not only to auroral emissions produced by precipitating particles,but also to dayglow emissions produced by photoelectrons induced by sunlight.Nightglow emissions and scattered sunlight can contribute to the background signal.To fully utilize such images in space science,background contamination must be removed to isolate the auroral signal.Here we outline a data-driven approach to modeling the background intensity in multiple images by formulating linear inverse problems based on B-splines and spherical harmonics.The approach is robust,flexible,and iteratively deselects outliers,such as auroral emissions.The final model is smooth across the terminator and accounts for slow temporal variations and large-scale asymmetries in the dayglow.We demonstrate the model by using the three far ultraviolet cameras on the Imager for Magnetopause-to-Aurora Global Exploration(IMAGE)mission.The method can be applied to historical missions and is relevant for upcoming missions,such as the Solar wind Magnetosphere Ionosphere Link Explorer(SMILE)mission.
基金Supported by the New National Excellence Program of the Ministry for Innovation and Technology From the Source of the National Research,Development and Innovation Fund,No.ÚNKP-22-4-SZTE-296,No.ÚNKP-23-3-SZTE-268,and No.ÚNKP-23-5-SZTE-719the EU’s Horizon 2020 Research and Innovation Program under Grant Agreement,No.739593.
文摘BACKGROUND Choosing an optimal post-polypectomy management strategy of malignant colorectal polyps is challenging,and evidence regarding a surveillance-only strategy is limited.AIM To evaluate long-term outcomes after endoscopic removal of malignant colorectal polyps.METHODS A single-center retrospective cohort study was conducted to evaluate outcomes after endoscopic removal of malignant colorectal polyps between 2010 and 2020.Residual disease rate and nodal metastases after secondary surgery and local and distant recurrence rate for those with at least 1 year of follow-up were invest-igated.Event rates for categorical variables and means for continuous variables with 95%confidence intervals were calculated,and Fisher’s exact test and Mann-Whitney test were performed.Potential risk factors of adverse outcomes were RESULTS In total,135 lesions(mean size:22.1 mm;location:42%rectal)from 129 patients(mean age:67.7 years;56%male)were enrolled.The proportion of pedunculated and non-pedunculated lesions was similar,with en bloc resection in 82%and 47%of lesions,respectively.Tumor differentiation,distance from resection margins,depth of submucosal invasion,lymphovascular invasion,and budding were reported at 89.6%,45.2%,58.5%,31.9%,and 25.2%,respectively.Residual tumor was found in 10 patients,and nodal metastasis was found in 4 of 41 patients who underwent secondary surgical resection.Univariate analysis identified piecemeal resection as a risk factor for residual malignancy(odds ratio:1.74;P=0.042).At least 1 year of follow-up was available for 117 lesions from 111 patients(mean follow-up period:5.59 years).Overall,54%,30%,30%,11%,and 16%of patients presented at the 1-year,3-year,5-year,7-year,and 9-10-year surveillance examinations.Adverse outcomes occurred in 9.0%(local recurrence and dissemination in 4 patients and 9 patients,respectively),with no difference between patients undergoing secondary surgery and surveillance only.CONCLUSION Reporting of histological features and adherence to surveillance colonoscopy needs improvement.Long-term adverse outcome rates might be higher than previously reported,irrespective of whether secondary surgery was performed.
基金supported by the National Natural Science Foundation of China(52375420,52005134 and51675453)Natural Science Foundation of Heilongjiang Province of China(YQ2023E014)+5 种基金Self-Planned Task(No.SKLRS202214B)of State Key Laboratory of Robotics and System(HIT)China Postdoctoral Science Foundation(2022T150163)Young Elite Scientists Sponsorship Program by CAST(No.YESS20220463)State Key Laboratory of Robotics and System(HIT)(SKLRS-2022-ZM-14)Open Fund of Key Laboratory of Microsystems and Microstructures Manufacturing(HIT)(2022KM004)Fundamental Research Funds for the Central Universities(Grant Nos.HIT.OCEF.2022024 and FRFCU5710051122)。
文摘Elucidating the complex interactions between the work material and abrasives during grinding of gallium nitride(GaN)single crystals is an active and challenging research area.In this study,molecular dynamics simulations were performed on double-grits interacted grinding of GaN crystals;and the grinding force,coefficient of friction,stress distribution,plastic damage behaviors,and abrasive damage were systematically investigated.The results demonstrated that the interacted distance in both radial and transverse directions achieved better grinding quality than that in only one direction.The grinding force,grinding induced stress,subsurface damage depth,and abrasive wear increase as the transverse interacted distance increases.However,there was no clear correlation between the interaction distance and the number of atoms in the phase transition and dislocation length.Appropriate interacted distances between abrasives can decrease grinding force,coefficient of friction,grinding induced stress,subsurface damage depth,and abrasive wear during the grinding process.The results of grinding tests combined with cross-sectional transmission electron micrographs validated the simulated damage results,i.e.amorphous atoms,high-pressure phase transition,dislocations,stacking faults,and lattice distortions.The results of this study will deepen our understanding of damage accumulation and material removal resulting from coupling between abrasives during grinding and can be used to develop a feasible approach to the wheel design of ordered abrasives.
基金the supports from Debris of the Anthropocene to Resources(DotA2)Lab at NTU.
文摘Photocatalysis offers a sustainable means for the oxidative removal of low concentrations of NOx(NO,NO2,N2O,N2O5,etc.)from the atmosphere.Layered double hydroxides(LDHs)are promising candidate photocatalysts owing to their unique layered and tunable chemical structures and abundant surface hydroxide(OH)moieties,which are hydroxyl radical(OH)precursors.However,the practical applications of LDHs are limited by their poor charge-separation ability and insufficient active sites.Herein,we developed a facile N_(2)H_(4)-driven etching approach to introduce dual Ni^(2+)and OHvacancies(Niv and OHv,respectively)into NiFe-LDH nanosheets(hereafter referred to as NiFe-LDH-et)to facilitate improved charge-carrier separation and active Lewis acidic site(Fe^(3+)and Ni^(2+)exposed at OHv)formation.In contrast to inert pristine LDH,NiFe-LDH-et actively removed NO under visible-light illumination.Specifically,Ni_(76)Fe_(24)-LDH-et etched with 1.50 mmol·L^(-1)N_(2)H_(4)solution removed 32.8%of the NO in continuously flowing air(NO feed concentration:500 parts per billion(ppb))under visible-light illumination,thereby outperforming most reported catalysts.Experimental and theoretical data revealed that the dual vacancies promoted the production of reactive oxygen species(O_(2)·^(-)andOH)and the adsorption of NO on the LDH.In situ spectroscopy demonstrated that NO was preferentially adsorbed at Lewis acidic sites,particularly exposed Fe^(3+)sites,converted into NO+,and subsequently oxidized to NO3without the notable formation of the more toxic intermediate NO2,thereby alleviating risks associated with its production and emission.
基金financial support from the National Key Research and Development Program of China(2018YFB0605003).
文摘Dust removal from pyrolytic vapors at high temperatures is an obstacle to the industrialization of the coal pyrolysis process.In this work,a granular bed with expanded perlites as filtration media was designed and integrated into a 10 t·d^(–1)coal pyrolysis facility.The testing results showed that around 97.56%dust collection efficiency was achieved.As a result,dust content in tar was significantly lowered.The pressure drop of the granular bed maintained in the range of 356 Pa to 489 Pa.The dust size in the effluent after filtration exhibited a bimodal distribution,which was attributed to the heterogeneity of the dust components.The effects of filtration bed on pyrolytic product yields were also discussed.A modified filtration model based on the macroscopic phenomenological theory was proposed to describe the performance of the granular bed.The computation results were well agreed with the experimental data.
文摘Lysosomes are discrete organelles that act as recycling centers for extracellular and intracellular materials,playing a pivotal role in maintaining cellular homeostasis.Their acidic environment,maintained by numerous hydrolytic enzymes,facilitates substrate degradation.Dysfunction in lysosomal processes can lead to abnormal substrate degradation,significantly impacting cellular homeostasis.High energy-demanding cells,such as post-mitotic neurons,are especially vulnerable to these changes,often resulting in neurological diseases.Autophagy,a conserved catabolic process,requires extensive lysosomal utilization.It plays a key role in removing unnecessary intracellular components,ensuring cellular homeostasis,and promoting cell survival during stress conditions such as starvation,infection,or cellular damage.
基金supported by National Institute of Health Grant NINDS NS16446 to JHK and NS067017 to HXQsupported by NIH NINDS NS129982 and NIH NEI EY002686 to JHK
文摘For decades,researchers have known that when neurons lose their activating inputs,they can atrophy and even die.For example,removing sensory nerve inputs from the arm to the spinal cord after amputation or cutting the spinal nerves can shrink the post-synaptic target zones(e.g.,Woods et al.,2000).From touch receptors for the hand and arm,primary nerve afferents enter the spinal cord,and axons travel in the dorsal columns to target the cuneate nucleus(Cu)of the brainstem on the same side of the body(Figure 1).When sensory loss is unilateral,the overwhelming result is for the associated primary target zone to shrink in total size(cross-sectional area),as compared to the size of the opposite side.
基金supported by the National Natural Science Foundation of China(No.82060806)the Guangxi Natural Science Foundation Project(No.2023GXNSFAA026461)+2 种基金the Interdisciplinary innovation research team for key technologies of traditional Chinese medicine,emerging biological materials,and intelligent equipment development(GZKJ2303)Graduate education innovation project of Guangxi University of Chinese Medicine(YCSZ2022008)the college student innovation and entrepreneurship training program of Guangxi University of Chinese Medicine(S202310600107,202310600241,S20221060053).
文摘Methicillin-resistant Staphylococcus aureus(MRSA)is a common pathogen causing acquired infections.Antibiotics are routinely employed for bacterial infection treatment.Excessive antibiotic use for bacterial infections heightens resistance,and MRSA resistance is being prevalent[1].MRSA exhibits substantial resistance to conventional antibiotics,which is associated with its biofilm-forming capability.The bacterial biofilm serves as a barrier,restricting nutrient access and slowing internal metabolism,increasing antibiotic resistance.The bacterial biofilm forms a defensive layer,resisting antibiotic penetration while preventing nutrient entry,inducing a slow bacterial metabolism,and increasing bacterial resistance[2].Consequently,biofilm formation and the emergence of resistance to conventional antibiotics have become substantial challenges in the field of infectious diseases.The development of agents to remove biofilm barriers is urgently required because biofilms are extremely hazardous.
文摘In the manufacturing of biotechnology drug products,the viral safety control strategy is a critical pharmaceutical quality management framework that contains three key elements:prevention,testing,and clearance.The prevention strategy involves rigorous screening for any adventitious virus contamination in the raw materials,reagents,and endogenous/adventitious virus contamination in the cell banks.