Citation： Utine CA, Engin Durmaz C, Koqak N. Corneal matrix repair therapy with the regenerating agent in neurotrophic persistent epithelial defects, lntJOphthalmo12017;10（12）：1935-1939
Microbiologically⁃induced calcite⁃precipitation(MICP)has been increasingly studied in structural repair including self⁃healing and external applications.Among various MICP pathways,enzymatic urea hydrolysis is suggest...Microbiologically⁃induced calcite⁃precipitation(MICP)has been increasingly studied in structural repair including self⁃healing and external applications.Among various MICP pathways,enzymatic urea hydrolysis is suggested to be applied as external repair instead of self⁃healing.This study comprehensively characterised the enzymatic urea hydrolysis pathway in physical,impermeable,and mechanical rejuvenation of concrete cracks.The visual quality of repaired structures was presented,and the importance of humidity in the remediation of cracks was demonstrated.Moreover,this study investigated the differences in the effectiveness of repair between premixing bacteria with urea and without any premixing.With premixing,there was a concern that the accelerated reactions would precipitate calcite in the shallow spaces of the cracks and impede deeper healing.However,the observed results indicated that neither physical nor impermeable rejuvenation of concrete cracks repair would be detrimentally affected.The results obtained from this study will allow further development in commercialisation since the effectiveness of repair has been confirmed with an improvement in its efficiency.展开更多
Peripheral nerve injuries are relatively common and can be caused by a variety of traumatic events such as motor vehicle accidents.They can lead to long-term disability,pain,and financial burden,and contribute to poor...Peripheral nerve injuries are relatively common and can be caused by a variety of traumatic events such as motor vehicle accidents.They can lead to long-term disability,pain,and financial burden,and contribute to poor quality of life.In this review,we systematically analyze the contemporary literature on peripheral nerve gap management using nerve prostheses in conjunction with physical therapeutic agents.The use of nerve prostheses to assist nerve regeneration across large gaps(> 30 mm) has revolutionized neural surgery.The materials used for nerve prostheses have been greatly refined,making them suitable for repairing large nerve gaps.However,research on peripheral nerve gap management using nerve prostheses reports inconsistent functional outcomes,especially when prostheses are integrated with physical therapeutic agents,and thus warrants careful investigation.This review explores the effectiveness of nerve prostheses for bridging large nerve gaps and then addresses their use in combination with physical therapeutic agents.展开更多
文摘Citation： Utine CA, Engin Durmaz C, Koqak N. Corneal matrix repair therapy with the regenerating agent in neurotrophic persistent epithelial defects, lntJOphthalmo12017;10（12）：1935-1939
基金Sponsored by the National Natural Science Foundation of China(Grant No.51278157).
文摘Microbiologically⁃induced calcite⁃precipitation(MICP)has been increasingly studied in structural repair including self⁃healing and external applications.Among various MICP pathways,enzymatic urea hydrolysis is suggested to be applied as external repair instead of self⁃healing.This study comprehensively characterised the enzymatic urea hydrolysis pathway in physical,impermeable,and mechanical rejuvenation of concrete cracks.The visual quality of repaired structures was presented,and the importance of humidity in the remediation of cracks was demonstrated.Moreover,this study investigated the differences in the effectiveness of repair between premixing bacteria with urea and without any premixing.With premixing,there was a concern that the accelerated reactions would precipitate calcite in the shallow spaces of the cracks and impede deeper healing.However,the observed results indicated that neither physical nor impermeable rejuvenation of concrete cracks repair would be detrimentally affected.The results obtained from this study will allow further development in commercialisation since the effectiveness of repair has been confirmed with an improvement in its efficiency.
文摘Peripheral nerve injuries are relatively common and can be caused by a variety of traumatic events such as motor vehicle accidents.They can lead to long-term disability,pain,and financial burden,and contribute to poor quality of life.In this review,we systematically analyze the contemporary literature on peripheral nerve gap management using nerve prostheses in conjunction with physical therapeutic agents.The use of nerve prostheses to assist nerve regeneration across large gaps(> 30 mm) has revolutionized neural surgery.The materials used for nerve prostheses have been greatly refined,making them suitable for repairing large nerve gaps.However,research on peripheral nerve gap management using nerve prostheses reports inconsistent functional outcomes,especially when prostheses are integrated with physical therapeutic agents,and thus warrants careful investigation.This review explores the effectiveness of nerve prostheses for bridging large nerve gaps and then addresses their use in combination with physical therapeutic agents.
