Viral hepatitis is an important challenge to public health worldwide.As hepatitis B is well controlled due to vaccination,the disease burden caused by the spread of hepatitis C has become increasingly prominent.Hepati...Viral hepatitis is an important challenge to public health worldwide.As hepatitis B is well controlled due to vaccination,the disease burden caused by the spread of hepatitis C has become increasingly prominent.Hepatitis C is an infectious disease that is mainly blood-borne.The rate of chronicity ranges from 55% to 85% after people are infected with the hepatitis C virus (HCV).展开更多
This report describes a hepatocellular carcinoma (HCC) with concomitant focal nodular hyperplasia (FNH) in a 56 years old Chinese man. There were two well circumscribed tumours measuring 3×2.5×2 cm and 2...This report describes a hepatocellular carcinoma (HCC) with concomitant focal nodular hyperplasia (FNH) in a 56 years old Chinese man. There were two well circumscribed tumours measuring 3×2.5×2 cm and 2×1.5×1.5 cm. The larger mass was grey and soft with a small area of bleeding and necrosis and an intact capsule. The smaller mass was yellow and had no capsule. Clonal analysis was carried out to clarify the relation between the HCC and the adjacent FNH. The clonal analysis was based on the methylation pattern of the polymorphic X chromosome linked androgen receptor gene (HUMARA). In FNH, after Hpa Ⅱ digestion, the allelic bands showed two well defined peaks. The intensity of the two peaks in the DNA from cirrhotic tissue did not differ significantly, consistent with a random pattern of X chromosome inactivation. However, in HCC, after Hpa Ⅱ digestion, the allelic bands differed significantly in intensity. Therefore, there was a typical polyclonal pattern of inactivation in FNH but the HCC was interpreted as being monoclonal.展开更多
1.This study is one of The Applied Economic Institutes Linkages Project(AERIL)which is funded by theCanadian International Development Agency(CIDA)and jiontly managed by The Conference Board of Canada(CBOC)and the Int...1.This study is one of The Applied Economic Institutes Linkages Project(AERIL)which is funded by theCanadian International Development Agency(CIDA)and jiontly managed by The Conference Board of Canada(CBOC)and the International Trade Research Institute in China.It is jointly implemented by the Institute ofEconomic Research of the Chinese State Planning Commission and the North—South Institute of Canada。展开更多
The automatic and accurate classification of Magnetic Resonance Imaging(MRI)radiology report is essential for the analysis and interpretation epilepsy and non-epilepsy.Since the majority of MRI radiology reports are u...The automatic and accurate classification of Magnetic Resonance Imaging(MRI)radiology report is essential for the analysis and interpretation epilepsy and non-epilepsy.Since the majority of MRI radiology reports are unstructured,the manual information extraction is time-consuming and requires specific expertise.In this paper,a comprehensive method is proposed to classify epilepsy and non-epilepsy real brain MRI radiology text reports automatically.This method combines the Natural Language Processing technique and statisticalMachine Learning methods.122 realMRI radiology text reports(97 epilepsy,25 non-epilepsy)are studied by our proposed method which consists of the following steps:(i)for a given text report our systems first cleans HTML/XML tags,tokenize,erase punctuation,normalize text,(ii)then it converts into MRI text reports numeric sequences by using indexbased word encoding,(iii)then we applied the deep learning models that are uni-directional long short-term memory(LSTM)network,bidirectional long short-term memory(BiLSTM)network and convolutional neural network(CNN)for the classifying comparison of the data,(iv)finally,we used 70%of used for training,15%for validation,and 15%for test observations.Unlike previous methods,this study encompasses the following objectives:(a)to extract significant text features from radiologic reports of epilepsy disease;(b)to ensure successful classifying accuracy performance to enhance epilepsy data attributes.Therefore,our study is a comprehensive comparative study with the epilepsy dataset obtained from numeric sequences by using index-based word encoding method applied for the deep learning models.The traditionalmethod is numeric sequences by using index-based word encoding which has been made for the first time in the literature,is successful feature descriptor in the epilepsy data set.The BiLSTM network has shown a promising performance regarding the accuracy rates.We show that the larger sizedmedical text reports can be analyzed by our proposed method.展开更多
The unmanned aerial vehicles( UAV) has been becoming more and more important in the aviation industry.Despite the superior performance and advanced technology,major accident of UAV happens frequently due to the impact...The unmanned aerial vehicles( UAV) has been becoming more and more important in the aviation industry.Despite the superior performance and advanced technology,major accident of UAV happens frequently due to the impact of their systems,long distance of remote control and skill of manipulator technology.According to the application of engineering application,failure mode effects and criticality analysis( FMECA),failure reporting analysis and corrective action comprehensive analysis systems( FRACAS)and fault tree analysis( FTA)( 3 F) were combined.And also a set of user-friendly,more time,more efficient and accurate reliability analysis system were explored.展开更多
Nonparametric and parametric subset selection procedures are used in the analysis of state homicide rates (SHRs), for the year 2005 and years 2014-2020, to identify subsets of states that contain the “best” (lowest ...Nonparametric and parametric subset selection procedures are used in the analysis of state homicide rates (SHRs), for the year 2005 and years 2014-2020, to identify subsets of states that contain the “best” (lowest SHR) and “worst” (highest SHR) rates with a prescribed probability. A new Bayesian model is developed and applied to the SHR data and the results are contrasted with those obtained with the subset selection procedures. All analyses are applied within the context of a two-way block design.展开更多
Disk failure prediction methods have been useful in handing a single issue,e.g.,heterogeneous disks,model aging,and minority samples.However,because these issues often exist simultaneously,prediction models that can h...Disk failure prediction methods have been useful in handing a single issue,e.g.,heterogeneous disks,model aging,and minority samples.However,because these issues often exist simultaneously,prediction models that can handle only one will result in prediction bias in reality.Existing disk failure prediction methods simply fuse various models,lacking discussion of training data preparation and learning patterns when facing multiple issues,although the solutions to different issues often conflict with each other.As a result,we first explore the training data preparation for multiple issues via a data partitioning pattern,i.e.,our proposed multi-property data partitioning(MDP).Then,we consider learning with the partitioned data for multiple issues as learning multiple tasks,and introduce the model-agnostic meta-learning(MAML)framework to achieve the learning.Based on these improvements,we propose a novel disk failure prediction model named MDP-MAML.MDP addresses the challenges of uneven partitioning and difficulty in partitioning by time,and MAML addresses the challenge of learning with multiple domains and minor samples for multiple issues.In addition,MDP-MAML can assimilate emerging issues for learning and prediction.On the datasets reported by two real-world data centers,compared to state-of-the-art methods,MDP-MAML can improve the area under the curve(AUC)and false detection rate(FDR)from 0.85 to0.89 and from 0.85 to 0.91,respectively,while reducing false alarm rate(FAR)from 4.88%to 2.85%.展开更多
文摘Viral hepatitis is an important challenge to public health worldwide.As hepatitis B is well controlled due to vaccination,the disease burden caused by the spread of hepatitis C has become increasingly prominent.Hepatitis C is an infectious disease that is mainly blood-borne.The rate of chronicity ranges from 55% to 85% after people are infected with the hepatitis C virus (HCV).
文摘This report describes a hepatocellular carcinoma (HCC) with concomitant focal nodular hyperplasia (FNH) in a 56 years old Chinese man. There were two well circumscribed tumours measuring 3×2.5×2 cm and 2×1.5×1.5 cm. The larger mass was grey and soft with a small area of bleeding and necrosis and an intact capsule. The smaller mass was yellow and had no capsule. Clonal analysis was carried out to clarify the relation between the HCC and the adjacent FNH. The clonal analysis was based on the methylation pattern of the polymorphic X chromosome linked androgen receptor gene (HUMARA). In FNH, after Hpa Ⅱ digestion, the allelic bands showed two well defined peaks. The intensity of the two peaks in the DNA from cirrhotic tissue did not differ significantly, consistent with a random pattern of X chromosome inactivation. However, in HCC, after Hpa Ⅱ digestion, the allelic bands differed significantly in intensity. Therefore, there was a typical polyclonal pattern of inactivation in FNH but the HCC was interpreted as being monoclonal.
文摘1.This study is one of The Applied Economic Institutes Linkages Project(AERIL)which is funded by theCanadian International Development Agency(CIDA)and jiontly managed by The Conference Board of Canada(CBOC)and the International Trade Research Institute in China.It is jointly implemented by the Institute ofEconomic Research of the Chinese State Planning Commission and the North—South Institute of Canada。
文摘The automatic and accurate classification of Magnetic Resonance Imaging(MRI)radiology report is essential for the analysis and interpretation epilepsy and non-epilepsy.Since the majority of MRI radiology reports are unstructured,the manual information extraction is time-consuming and requires specific expertise.In this paper,a comprehensive method is proposed to classify epilepsy and non-epilepsy real brain MRI radiology text reports automatically.This method combines the Natural Language Processing technique and statisticalMachine Learning methods.122 realMRI radiology text reports(97 epilepsy,25 non-epilepsy)are studied by our proposed method which consists of the following steps:(i)for a given text report our systems first cleans HTML/XML tags,tokenize,erase punctuation,normalize text,(ii)then it converts into MRI text reports numeric sequences by using indexbased word encoding,(iii)then we applied the deep learning models that are uni-directional long short-term memory(LSTM)network,bidirectional long short-term memory(BiLSTM)network and convolutional neural network(CNN)for the classifying comparison of the data,(iv)finally,we used 70%of used for training,15%for validation,and 15%for test observations.Unlike previous methods,this study encompasses the following objectives:(a)to extract significant text features from radiologic reports of epilepsy disease;(b)to ensure successful classifying accuracy performance to enhance epilepsy data attributes.Therefore,our study is a comprehensive comparative study with the epilepsy dataset obtained from numeric sequences by using index-based word encoding method applied for the deep learning models.The traditionalmethod is numeric sequences by using index-based word encoding which has been made for the first time in the literature,is successful feature descriptor in the epilepsy data set.The BiLSTM network has shown a promising performance regarding the accuracy rates.We show that the larger sizedmedical text reports can be analyzed by our proposed method.
基金Naional Natural Science Foundntion of China(No.71761030)
文摘The unmanned aerial vehicles( UAV) has been becoming more and more important in the aviation industry.Despite the superior performance and advanced technology,major accident of UAV happens frequently due to the impact of their systems,long distance of remote control and skill of manipulator technology.According to the application of engineering application,failure mode effects and criticality analysis( FMECA),failure reporting analysis and corrective action comprehensive analysis systems( FRACAS)and fault tree analysis( FTA)( 3 F) were combined.And also a set of user-friendly,more time,more efficient and accurate reliability analysis system were explored.
文摘Nonparametric and parametric subset selection procedures are used in the analysis of state homicide rates (SHRs), for the year 2005 and years 2014-2020, to identify subsets of states that contain the “best” (lowest SHR) and “worst” (highest SHR) rates with a prescribed probability. A new Bayesian model is developed and applied to the SHR data and the results are contrasted with those obtained with the subset selection procedures. All analyses are applied within the context of a two-way block design.
基金Project supported by the National Natural Science Foundation of China(No.61902135)the Shandong Provincial Natural Science Foundation,China(No.ZR2019LZH003)。
文摘Disk failure prediction methods have been useful in handing a single issue,e.g.,heterogeneous disks,model aging,and minority samples.However,because these issues often exist simultaneously,prediction models that can handle only one will result in prediction bias in reality.Existing disk failure prediction methods simply fuse various models,lacking discussion of training data preparation and learning patterns when facing multiple issues,although the solutions to different issues often conflict with each other.As a result,we first explore the training data preparation for multiple issues via a data partitioning pattern,i.e.,our proposed multi-property data partitioning(MDP).Then,we consider learning with the partitioned data for multiple issues as learning multiple tasks,and introduce the model-agnostic meta-learning(MAML)framework to achieve the learning.Based on these improvements,we propose a novel disk failure prediction model named MDP-MAML.MDP addresses the challenges of uneven partitioning and difficulty in partitioning by time,and MAML addresses the challenge of learning with multiple domains and minor samples for multiple issues.In addition,MDP-MAML can assimilate emerging issues for learning and prediction.On the datasets reported by two real-world data centers,compared to state-of-the-art methods,MDP-MAML can improve the area under the curve(AUC)and false detection rate(FDR)from 0.85 to0.89 and from 0.85 to 0.91,respectively,while reducing false alarm rate(FAR)from 4.88%to 2.85%.