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Synoptic review on existing and potential sources for bias in dental research methodology with methods on their prevention and remedies
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作者 Amit Arvind Agrawal Nilima Prakash +3 位作者 Mohammad Almagbol Mohammed Alobaid Abdullah Alqarni Hammam Altamni 《World Journal of Methodology》 2023年第5期426-438,共13页
The results of years of dental study serve as the foundation for the practise of medicine and,for that matter,dentistry.Doctors may have their own preferences for techniques and materials,but whether directly or indir... The results of years of dental study serve as the foundation for the practise of medicine and,for that matter,dentistry.Doctors may have their own preferences for techniques and materials,but whether directly or indirectly,their decisions are influenced by systematic reviews and meta-analyses.However,due to poorly conducted or presented research,this very basic foundation may not be reliable.Bias in research is one of several factors that might make study results or research itself unreliable.Bias can be introduced into research at many stages,deliberately or unknowingly.Bias can appear at any point during the research process,even before the study itself begins.There are many biases in research,but some of them are more relevant to dentistry research than others.Because it is said that“eyes see what the mind knows”,it is essential to have a complete understanding of the different types of bias,how and when they get entrenched,and what steps may be taken to prevent or lessen them if they do occur.This comprehensive summary of bias in dentistry research is provided by this synoptic review.The goal is to identify gaps and measures that have been taken-or that should have been taken-by providing both descriptive and evaluative summaries,as well as examples from the literature,when needed. 展开更多
关键词 Dental research Bias(epidemiology) research methodology research design Epidemiologic methods
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Paradigm Shifts or Methodology Changes ? Think Twice Before You Put Paradigms into Practice 被引量:1
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作者 Cormspondence: Yang Yonglin,Department Of Foreign Languages,Tsinghua University Beliing,P. R. China 《现代外语》 CSSCI 北大核心 1999年第4期420-420,共1页
ThepresentpaperaddressestheapplicabilityofKuhn'stheoryofparadigmshiftsandscientificrevolutionstothefieldoflanguageteaching.First,itillustratestheconceptionofparadigmshiftsandscientificrevolutions.Andthen,itsetsupt... ThepresentpaperaddressestheapplicabilityofKuhn'stheoryofparadigmshiftsandscientificrevolutionstothefieldoflanguageteaching.First,itillustratestheconceptionofparadigmshiftsandscientificrevolutions.Andthen,itsetsuptwotestsforexaminingtheissueofwhetherK... 展开更多
关键词 linguistic theory PSYCHOLOGY paradigm SHIFTS scientific REVOLUTIONS language teaching ECLECTICISM methodology
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Delphi methodology in healthcare research:How to decide its appropriateness 被引量:33
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作者 Prashant Nasa Ravi Jain Deven Juneja 《World Journal of Methodology》 2021年第4期116-129,共14页
The Delphi technique is a systematic process of forecasting using the collective opinion of panel members.The structured method of developing consensus among panel members using Delphi methodology has gained acceptanc... The Delphi technique is a systematic process of forecasting using the collective opinion of panel members.The structured method of developing consensus among panel members using Delphi methodology has gained acceptance in diverse fields of medicine.The Delphi methods assumed a pivotal role in the last few decades to develop best practice guidance using collective intelligence where research is limited,ethically/logistically difficult or evidence is conflicting.However,the attempts to assess the quality standard of Delphi studies have reported significant variance,and details of the process followed are usually unclear.We recommend systematic quality tools for evaluation of Delphi methodology;identification of problem area of research,selection of panel,anonymity of panelists,controlled feedback,iterative Delphi rounds,consensus criteria,analysis of consensus,closing criteria,and stability of the results.Based on these nine qualitative evaluation points,we assessed the quality of Delphi studies in the medical field related to coronavirus disease 2019.There was inconsistency in reporting vital elements of Delphi methods such as identification of panel members,defining consensus,closing criteria for rounds,and presenting the results.We propose our evaluation points for researchers,medical journal editorial boards,and reviewers to evaluate the quality of the Delphi methods in healthcare research. 展开更多
关键词 Delphi studies Quality tools for methodology research methods Delphi technique CONSENSUS Expert panel Coronavirus disease 2019 SARS-CoV-2
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Biobanks and biomarkers:Their current and future role in biomedical research
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作者 Michael Colwill Samantha Baillie +1 位作者 Richard Pollok Andrew Poullis 《World Journal of Methodology》 2024年第4期77-83,共7页
The importance and utility of biobanks has increased exponentially since their inception and creation.Initially used as part of translational research,they now contribute over 40%of data for all cancer research papers... The importance and utility of biobanks has increased exponentially since their inception and creation.Initially used as part of translational research,they now contribute over 40%of data for all cancer research papers in the United States of America and play a crucial role in all aspects of healthcare.Multiple classification systems exist but a simplified approach is to either classify as population-based or disease-oriented entities.Whilst historically publicly funded institutions,there has been a significant increase in industry funded entities across the world which has changed the dynamic of biobanks offering new possibilities but also new challenges.Biobanks face legal questions over data sharing and intellectual property as well as ethical and sustainability questions particularly as the world attempts to move to a low-carbon economy.International collaboration is required to address some of these challenges but this in itself is fraught with complexity and difficulty.This review will examine the current utility of biobanks in the modern healthcare setting as well as the current and future challenges these vital institutions face. 展开更多
关键词 BIOBANKS Biomarkers Biomedical research research methodology research ethics
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Research on Knowledge Pluralistic Integration of English Teaching Methodology in Higher Vocational Colleges
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作者 龙亮 《疯狂英语(理论版)》 2017年第1期74-76,共3页
For colleges and universities,especially higher vocational colleges,personnel training should focus on the cultivation of inter-disciplinary talents,so as to meet the needs of society and the labor market.This require... For colleges and universities,especially higher vocational colleges,personnel training should focus on the cultivation of inter-disciplinary talents,so as to meet the needs of society and the labor market.This requires pluralistic knowledge integration in the process of teaching.This paper starts from the necessity of knowledge pluralistic integration of English teaching methodology,learns the necessity of the integration and studies the specific pathways and methods of the integration,hoping to provide reference for peers. 展开更多
关键词 higher vocational colleges English teaching methodology pluralistic integration pathway research
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Research surveys and their evolution:Past,current and future uses in healthcare
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作者 Michael Colwill Richard Pollok Andrew Poullis 《World Journal of Methodology》 2024年第4期91-95,共5页
Research surveys are believed to have originated in antiquity with evidence of them being performed in ancient Egypt and Greece.In the past century,their use has grown significantly and they are now one of the most fr... Research surveys are believed to have originated in antiquity with evidence of them being performed in ancient Egypt and Greece.In the past century,their use has grown significantly and they are now one of the most frequently employed research methods including in the field of healthcare.Modern validation techniques and processes have allowed researchers to broaden the scope of qualitative data they can gather through these surveys such as an individual’s views on service quality to nationwide surveys that are undertaken regularly to follow healthcare trends.This article focuses on the evolution and current utility of research surveys,different methodologies employed in their creation,the advantages and disadvantages of different forms and their future use in healthcare research.We also review the role artificial intelligence and the importance of increased patient participation in the development of these surveys in order to obtain more accurate and clinically relevant data. 展开更多
关键词 research surveys methodology Sampling Artificial intelligence
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Methodology and Trends of Linguistic Research in the Era of Big Data
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作者 Liu Haitao Lin Yanni 《Contemporary Social Sciences》 2020年第4期87-106,共20页
This paper presents methodology and trends of linguistic research in the era of big data.We begin with a discussion of the role of linguists in the information society and illustrate the opportunities and challenges l... This paper presents methodology and trends of linguistic research in the era of big data.We begin with a discussion of the role of linguists in the information society and illustrate the opportunities and challenges linguists are currently facing.After highlighting the significance of authentic data on linguistic research,we argue that language is a complex adaptive system driven by humans.Then,from the perspective of philosophy of science,we introduce the research paradigm of quantitative linguistics through several cases.Finally,we discuss how China’s linguistic research will benefit from the data-intensive approach in terms of scientification and internationalization. 展开更多
关键词 LINGUISTICS big data the data-intensive approach scientific research paradigm
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Encouraging Critical Thinking: Research-oriented Teaching in English Teaching Methodology Course in Teachers' Colleges
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作者 Wang Jianqing 《大学英语教学与研究》 2011年第3期3-9,共7页
关键词 英语教学 教学方法 阅读 翻译
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An Innovative Soft Design Science Methodology for Improving Development of a Secure Information System in Tanzania Using Multi-Layered Approach 被引量:2
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作者 Maduhu Mshangi Edephonce Ngemera Nfuka Camilius Sanga 《Journal of Information Security》 2017年第3期141-165,共25页
This paper presents an innovative Soft Design Science Methodology for improving information systems security using multi-layered security approach. The study applied Soft Design Science Methodology to address the prob... This paper presents an innovative Soft Design Science Methodology for improving information systems security using multi-layered security approach. The study applied Soft Design Science Methodology to address the problematic situation on how information systems security can be improved. In addition, Soft Design Science Methodology was compounded with mixed research methodology. This holistic approach helped for research methodology triangulation. The study assessed security requirements and developed a framework for improving information systems security. The study carried out maturity level assessment to determine security status quo in the education sector in Tanzania. The study identified security requirements gap (IT security controls, IT security measures) using ISO/IEC 21827: Systems Security Engineering-Capability Maturity Model (SSE-CMM) with a rating scale of 0 - 5. The results of this study show that maturity level across security domain is 0.44 out of 5. The finding shows that the implementation of IT security controls and security measures for ensuring security goals are lacking or conducted in ad-hoc. Thus, for improving the security of information systems, organisations should implement security controls and security measures in each security domain (multi-layer security). This research provides a framework for enhancing information systems security during capturing, processing, storage and transmission of information. This research has several practical contributions. Firstly, it contributes to the body of knowledge of information systems security by providing a set of security requirements for ensuring information systems security. Secondly, it contributes empirical evidence on how information systems security can be improved. Thirdly, it contributes on the applicability of Soft Design Science Methodology on addressing the problematic situation in information systems security. The research findings can be used by decision makers and lawmakers to improve existing cyber security laws, and enact laws for data privacy and sharing of open data. 展开更多
关键词 SOFT DESIGN SCIENCE Information SYSTEMS Security DESIGN SCIENCE research SOFT SYSTEMS methodology Multi-Layered APPROACH
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Paradigms and Methodologies for Knowledge Building
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作者 Josep Gallifa 《Review of Educational Theory》 2018年第3期70-81,共12页
A diversity of methodologies can be utilized for knowledge building in social sciences, particularly in education. Nevertheless, in order to give meaning to the research findings and progressively create theories, an ... A diversity of methodologies can be utilized for knowledge building in social sciences, particularly in education. Nevertheless, in order to give meaning to the research findings and progressively create theories, an awareness of the epistemological framework appears to be necessary. The aim of this article is to present the main epistemological paradigms and their coherent correspondence with respective ontologies and corresponding methodologies. This article supports and describes four paradigms or epistemological traditions: logic empiricism, constructivism, conceptualism or Aristotelian tradition, and phenomenology. Understanding the diverse possible epistemologies as well as the coherence with methodologies is a necessary step for presenting well-informed research. Knowledge building requires comparison, replication, generalization or integration of results in theories, and all these processes need the critical instance of the epistemological and methodological coherence. Additionally some concrete examples of methodologies have been detailed to illustrate the diversity of available ways of knowledge building in education. The Review of Educational Theory, as a new journal that aims to create a scientific community, will increase the research quality by enhancing the epistemological and methodological awareness of their pieces of research. 展开更多
关键词 Knowledge building Epistemologies research methodologIES Ontologies LOGIC EMPIRICISM CONSTRUCTIVISM Aristotelian TRADITION PHENOMENOLOGY
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Sociolinguistic Research in Single Parent Families in China: a Methodological Perspective
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作者 徐嗣群 《海外英语》 2019年第22期106-107,118,共3页
It is extremely difficult to collect naturally occurring interactions in private settings.In this article,I discuss the back⁃ground of the research,and show the evidence that where the research can fit into the litera... It is extremely difficult to collect naturally occurring interactions in private settings.In this article,I discuss the back⁃ground of the research,and show the evidence that where the research can fit into the literature,and discuss the possible strategies that we can use to collect naturally occurring interactions in informal settings. 展开更多
关键词 SOCIOLINGUISTICS single parent family research methodology
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On the Positioning, Contents, and Methodology of Human Rights Law Study
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作者 于文豪 HU Liang 《The Journal of Human Rights》 2017年第6期549-564,共16页
The ideal model of human rights law studies shall be one that is open and comprehensive. On the basis of normative legal studies, it shall pay more attention to and respond to political, economic, and social developme... The ideal model of human rights law studies shall be one that is open and comprehensive. On the basis of normative legal studies, it shall pay more attention to and respond to political, economic, and social development in a wide range of human rights issues. These studies should attempt to find practical solutions to concrete problems. Human rights law should be a relatively independent legal discipline, and it should be a problem-oriented object of study. Regarding the research methodologies, human rights law could encompass all aspects of legal studies, and go beyond legal them to some extent to encompass the influence of other disciplines. 展开更多
关键词 human rights human rights law object of study research methodologies interdisciplinary studies
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Factors and expectations influencing concussion disclosure within NCAA DivisionⅠathletes:A mixed methodological approach
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作者 Melissa C.Kay Heidi Hennink-Kaminski +8 位作者 Zachary Y.Kerr Paula Gildner Brittany M.Ingram Kenneth L.Cameron Megan N.Houston Laura A.Linnan Stephen W.Marshall Karen Y.Peck Johna K.Register-Mihalik 《Journal of Sport and Health Science》 SCIE CSCD 2023年第3期388-397,共10页
Background:Participation in sports is associated with many benefits to all aspects of health;however,it also comes with the risk of injury,particularly concussions.Self-disclosure and care seeking following a concussi... Background:Participation in sports is associated with many benefits to all aspects of health;however,it also comes with the risk of injury,particularly concussions.Self-disclosure and care seeking following a concussion are especially important because of the lack of outwardly visible signs and/or symptoms.Although recent research has explored factors affecting concussion disclosure,use of isolated methodologies limits the ability to contextualize how disclosure or nondisclosure occurs.Therefore,the purpose of this study was to describe the factors and expectations of National Collegiate Athletic Association(NCAA)athletes that may influence concussion disclosure.Methods:This mixed-methods convergent parallel research study included 25 NCAA Division I athletes representing 13 sports,all of whom completed a concussion-education session with pre-/post-test surveys and a semistructured interview.Eligible athletes were at least 18 years old and on an NCAA roster.The surveys focused on previous concussion-related disclosure behaviors,knowledge,attitudes,beliefs,norms,and intentions about disclosing concussion.Interviews focused on the athletes’experiences related to concussion disclosure.Survey data were analyzed using descriptive statistics and Mann-Whitney U tests.Interviews were analyzed using a Consensual Qualitative Research tradition.Results:Participants had good concussion knowledge(median=46.0),positive attitudes(median=38.0),strong beliefs(median=13.0),and strong intentions to disclose concussion symptoms(median=7.0).None of the constructs differed by participants’gender.Although quantitative findings were mostly positive,interview data highlighted factors that may explain why some participants are successful in disclosing concussions and why others may find disclosure difficult.Educational efforts,sport culture,and medical professional presence were the primary facilitators discussed by participants.Stigma,pressure,and a lack of team support were perceived as disclosure barriers.Conclusion:The context in which concussion disclosure occurs or does not occur is vital to the success of educational interventions.Interventions must prioritize stakeholder-and team-based perspectives on concussion to establish a network supportive to disclosure. 展开更多
关键词 Education Medical professional presence Mixed methodological research Reporting Sport culture
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The Challenges of Identifying and Managing Epistemic Inequalities in PHIR(Population Health Intervention Research):An Illustration in the Conception and Implementation of a TPE(Therapeutic Patient Education)Program in Oncology
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作者 Philippe Terral Charlotte Bruneau Jean-Paul Génolini 《Psycho-Oncologie》 SCIE 2023年第3期181-189,共9页
Aims:The joint dynamics of knowledge(of patients,health professionals,decision-makers,researchers)and of the powers(of speech and action,asymmetries,and hierarchies established between individuals and their knowledge)... Aims:The joint dynamics of knowledge(of patients,health professionals,decision-makers,researchers)and of the powers(of speech and action,asymmetries,and hierarchies established between individuals and their knowledge)of the people who carry them at the heart of the PHIR,are analyzed from the perspective of the management of epistemic inequalities.We study the nature of knowledge sharing or non-sharing between these different categories of agents involved in health interventions.Procedure:The qualitative methodology is based on 36 interviews and six years of ethnographic observations of the TPE program(design or implementation),as well as steering committees and workshops of the PHIR where researchers,decisionmakers,health professionals,and patients share their experiences and knowledge.Results:The research highlights three major theoretical and methodological issues of PHIR concerning epistemic inequalities.We argue for broadening the spectrum of health expertise(researchers,decision-makers,health professionals,patients)and for their pluralization.To account for the nature and evolution of collaborations,it is necessary to closely study the dynamics of the avenues of coordination between these fields of expertise.Finally,we call to identify the resources(knowledge,values,material elements,etc.)and strengths that enable these hybrid groups to bind(or not)and to potentially generate co-learning.Conclusion:Considering these three major issues allows PHIR to reflect and take action to reduce inequalities by linking epistemic and social issues. 展开更多
关键词 Epistemic inequalities intervention research theoretical issues methodological issues
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In vitro laboratory infection research in orthopaedics:Why,when,and how
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作者 Konstantinos Tsikopoulos Lorenzo Drago +4 位作者 Gabriele Meroni Dimitrios Kitridis Byron Chalidis Fotios Papageorgiou Paraskevi Papaioannidou 《World Journal of Orthopedics》 2023年第8期598-603,共6页
The musculoskeletal system involves multiple tissues which are constantly exposed to being exposed to various biological and mechanical stimuli.As such,isolating and studying a particular system from a complex human c... The musculoskeletal system involves multiple tissues which are constantly exposed to being exposed to various biological and mechanical stimuli.As such,isolating and studying a particular system from a complex human clinical environment is not always a realistic expectation.On top of that,recruitment limitations,in addition to the nature of orthopaedic interventions and their associated cost,sometimes preclude consideration of human trials to answer a clinical question.Therefore,in this mini review,we sought to rationalize the rapid evolution of biomedical research at a basic scientific level and explain why the perception of orthopaedic conditions has fundamentally changed over the last decades.In more detail,we highlight that the number of orthopaedic in vitro publications has soared since 1990.Last but not least,we elaborated on the minimum requirements for conducting a scientifically sound infection-related laboratory experiment to offer valuable information to clinical practitioners.We also explained the rationale behind implementing molecular biology techniques,ex vivo experiments,and artificial intelligence in this type of laboratory research. 展开更多
关键词 BIOFILM In vitro Laboratory research methodology
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基于“四个面向”的高校“有组织科研”范式构建--一个单案例研究 被引量:9
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作者 吴正刚 刘宇奇 《科技进步与对策》 CSSCI 北大核心 2024年第2期46-56,共11页
当今世界正经历百年未有之大变局,世界各国科技竞争加剧,科技创新成为各国博弈的主战场。我国在基础研究、关键核心技术等领域正在遭受西方发达国家的围堵。高校作为基础研究主力军和重大科技突破策源地,传统科研范式在响应国家重大需... 当今世界正经历百年未有之大变局,世界各国科技竞争加剧,科技创新成为各国博弈的主战场。我国在基础研究、关键核心技术等领域正在遭受西方发达国家的围堵。高校作为基础研究主力军和重大科技突破策源地,传统科研范式在响应国家重大需求方面存在原始创新能力薄弱、科技成果转化率低、协同创新能力不足等问题。持续增大的外部压力、创新高风险与高投入使得“有组织科研”成为当前我国高校提升创新效能的重要选择,也是高校深度融入国家创新体系的重要举措。阐述“四个面向”和“有组织科研”的内涵,梳理“四个面向”与“有组织科研”、“有组织科研”与自由探索的关系,从高校传统科研范式亟待解决的问题入手,构建基于“四个面向”的高校“有组织科研”范式,对重庆大学“有组织科研”实施路径与成效进行解析,验证理论的科学性与适用性。 展开更多
关键词 “四个面向” 有组织科研 组织模式 科研范式
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智能时代人因科学研究的新范式取向及重点 被引量:2
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作者 许为 高在峰 葛列众 《心理学报》 CSSCI CSCD 北大核心 2024年第3期363-382,共20页
本文首先提出了“人因科学”这一创新的学科群概念来表征工程心理学、人因工程、工效学、人机交互等相近领域。尽管这些领域的研究角度不一样,但是它们分享共同的研究理念、对象以及目的。我们近期的研究表明,人工智能(AI)新技术带来了... 本文首先提出了“人因科学”这一创新的学科群概念来表征工程心理学、人因工程、工效学、人机交互等相近领域。尽管这些领域的研究角度不一样,但是它们分享共同的研究理念、对象以及目的。我们近期的研究表明,人工智能(AI)新技术带来了一系列新的人因问题,而作为人因科学研究对象的人机关系呈现出从“人机交互”向“人智组队式合作”的跨时代演进。这些变化对人因科学研究提出了新问题和新挑战,需要我们重新审视基于非智能技术的人因科学研究范式和重点。在此背景下,本文梳理人因科学研究范式取向跨时代的演进,总结我们近5年所提出的一系列用于丰富人因科学研究范式的新概念模型和框架,其中包括人智协同认知系统、人智协同认知生态系统以及智能社会技术系统的模型和框架。本文进一步从人因科学研究范式取向的角度进一步提升这些概念模型和框架,提出智能时代人因科学研究的三种新范式取向,分析相应的应用意义,并展望今后的研究方向。同时,针对智能时代人因科学研究重点的跨时代转移新特征,本文从“人智交互”“智能人机界面”“人智组队合作”三个方面展望了今后人因科学的研究重点,揭示出人因科学新研究范式取向对未来研究重点的作用。我们认为,人因科学的研究范式取向和研究重点互为影响,互为促进,智能时代的人因科学研究需要多样化、创新的研究范式取向,从而进一步推动人因科学的发展。 展开更多
关键词 人因科学 工程心理学 人因工程 研究范式取向 人智组队
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领域法学视野下的数字法问题 被引量:11
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作者 彭诚信 《政法论丛》 CSSCI 北大核心 2024年第1期3-14,共12页
数字法律现象呈现出客体复合性、主体多样性及法律关系多元性特征,决定了传统研究范式转型升级成为数字法学的必然选择。领域法学作为调整交叉领域法现象的研究范式,与数字法问题相吻合。领域法学具体化、立体化以及复合化思维,可与部... 数字法律现象呈现出客体复合性、主体多样性及法律关系多元性特征,决定了传统研究范式转型升级成为数字法学的必然选择。领域法学作为调整交叉领域法现象的研究范式,与数字法问题相吻合。领域法学具体化、立体化以及复合化思维,可与部门法学协同互补;其立体性、自足性和因应性特征可对传统法学研究方法进行吸收和补充。运用领域法学研究范式,可立体化提炼数字法现象,多维度整合数字交叉学科,以达到全方位解决数字法问题的效果。在宏观上,归纳“数字赋权-代码规制-数字正义”的数字治理逻辑;在微观上,演绎数据权利分类确定、数据交易分层规范、算法治理多元共治、权益救济多方协同的数字治理机制,构建完整的数字法学知识体系。 展开更多
关键词 数字法学 领域法学 研究范式 交叉学科
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2023年LIS期刊论文研究方法应用态势 被引量:1
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作者 马岩 郑建明 刘佳静 《图书馆论坛》 CSSCI 北大核心 2024年第8期8-13,共6页
研究方法的选择和运用影响研究的深度和可靠性,对科学研究发展十分重要。文章在总结LIS领域方法论研究的基础上,将LIS领域常用的研究方法整理、汇总、编码,以LIS领域11种TOP期刊2023年收录的论文为数据源,统计分析LIS期刊论文的研究方... 研究方法的选择和运用影响研究的深度和可靠性,对科学研究发展十分重要。文章在总结LIS领域方法论研究的基础上,将LIS领域常用的研究方法整理、汇总、编码,以LIS领域11种TOP期刊2023年收录的论文为数据源,统计分析LIS期刊论文的研究方法应用态势,探讨LIS学科性质、研究对象、作者学科背景等因素对研究方法的影响。研究发现:LIS领域论文使用的研究方法内容不断演进,跨学科和新兴理论方法以及多元研究方法的应用促进了研究的深入和丰富。 展开更多
关键词 LIS研究 研究方法 方法论 统计分析
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基于科研范式变革的实验动物资源创新发展 被引量:1
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作者 贺争鸣 陈洪岩 +3 位作者 陈振文 孙岩松 巩薇 梁春南 《实验动物科学》 2024年第1期84-88,共5页
实验动物是支撑生命科学和生物医药等领域科技创新的重要基础科研条件之一。随着科研范式的变革,准确把握科学前沿和国家重大需求,进一步凝练实验动物资源创制与发展中的难点和疑点,对加快推动实验动物新品种/新品系开发和动物模型创制... 实验动物是支撑生命科学和生物医药等领域科技创新的重要基础科研条件之一。随着科研范式的变革,准确把握科学前沿和国家重大需求,进一步凝练实验动物资源创制与发展中的难点和疑点,对加快推动实验动物新品种/新品系开发和动物模型创制与发展具有重要意义。本文梳理了我国实验动物资源建设和应用情况,就应对新形势下的科研范式变革中存在的主要问题进行了深入探讨,展望了我国实验动物资源发展新动向,以期为实验动物新资源研究开发提供新视角。 展开更多
关键词 实验动物 动物模型 科研范式 问题凝练 创新思维 新视角
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