Study of Impacts of Small Business Innovation Research Programs

The development and commercialization of new technologies are important to the global economy. In this paper, the author first addresses Small Business Innovation Research （SBIR） background ; then, implicitly defines SBIR ; finally, I also analyze the impacts of smaU business innovation research programs. There are four aspects ： entrepreneurial orientation; environmental factors; organizational factors and performanee.

Eighty research programs win medical science awards

Eighty medical science research programs won national awards at the Great Hall of the People here Monday, with more than 2000 representatives from the sector attending the award ceremony.

A Research Program of Spherical Tokamak in China

The mission of this program is to explore the spherical torus plasma with a SUNIST spherical tokamak. Main experiments in the start phase will be involved with breakdown and plasma current set-up with a mode of saving volt-second and without ohmic heating system, equilibrium and instability, current driving, heating and profile modification. The SUNIST is a university-scale conceptual spherical tokamak, with R = 0.3 m, A 1.3, Ip - 50 kA, BT < 0.15 T, and PRF - 100 kW. The only peculiarity of SUNIST is that there is a toroidal insulating break along the outer wall of vacuum vessel. The expected that advantages of this arrangement are helpful not only for saving flux swing, but also for having a deep understanding of what will influence the discharge startup and globe performances of plasma under different conditions of strong vessel eddy and ECR power assistance. Of course, the vessel structure of cross seal will be at a great risk of controlling vacuum quality, although we have achieved positive results on simulation test and vacuum vessel test.

Mash1 efficiently reprograms rat astrocytes into neurons

To date, it remains poorly understood whether astrocytes can be easily reprogrammed into neurons. Mashl and Brn2 have been previously shown to cooperate to reprogram fibroblasts into neurons. In this study, we examined astrocytes from 2-month-old Sprague-Dawley rats, and found that Brn2 was expressed, but Mashl was not detectable. Thus, we hypothesized that Mashl alone could be used to reprogram astrocytes into neurons. We transfected a recombinant MSCV-MASH1 plasmid into astrocytes for 72 hours, and saw that all cells expressed Mashl. One week later, we observed the changes in morphology of astrocytes, which showed typical neuro- nal characteristics. Moreover, β-tubulin expression levels were significantly higher in astrocytes expressing Mashl than in control cells. These results indicate that Mashl alone can reprogram astrocytes into neurons.

National Basic Research Program of China (973 Program) Indo-Pacific Oceanic Channel Project Special Issue

1 INTRODUCTION The tropical Indo-Pacific Oceans span over twothirds of the global tropical oceans.A major warm pool with the highest large-scale sea surface temperature of the global oceans is located in the western Pacific and eastern Indian Oceans.The climate systems over the tropical Pacific and Indian Oceans are subject to strong ocean-atmosphere coupling at multiple scales from intraseasonal to interannual,and to centennial.The

Special Topic on Major Research Program: Catalysis Science for Carbon-based Energy Conversion

The major research program,"Catalysis science for carbon-based energy conversion",from the national science foundation of China(NSFC)answers to the main strategic needs of China for the efficien use of carbon-based energy and targets to address the key scientifi issues involved in the catalytic interfaces.The research program aims to improve the catalytic activation of C–H and C–O bonds and the C–C coupling process,

China to Open State Research Program to Overseas Scientists

China will open part of its civil projects in national research program, including hi-tech development programs and major basic research programs to overseas scientists, said a senior official with the Ministry of Science and Technology (MOST). Facing the globalization trend in terms of economy and S&T development, China will take a

Foreign Scientists Join National Research Program for the First Time

Aproposal to carry out research into the chemistry of molecular agglomerate, jointly made by Tong Zhenhe with CAS Institute of Physical and Chemical Technologies, Jiang Xikui with Shanghai Institute of Organic Chemistry, Shen Jiaocong of Jilin University, and two German and

Marine Research Accomplishments by CAS under National 863 Program

This article gives a systematic and comprehensive summary of the marine research results ac complished by the Chinese Academy of Sciences (CAS) with the support of the National High-tech Research and Development Program during the period of the Ninth Five-year Plan (1996 - 2000). It includes achievements in the exploitation of marine resources, protection of the marine environment, reduction of marine disasters and the safeguarding of national marine sovereignty.

Baicalin suppresses iron accumulation after substantia nigra injury: relationship between iron concentration and transferrin expression

Previous studies have shown that baicalin prevented iron accumulation after substantia nigra injury, reduced divalent metal transporter 1 expression, and increased ferroportin 1 expression in the substantia nigra of rotenone-induced Parkinson＇s disease rats. In the current study, we investigated the relationship between iron accumulation and transferrin expression in C6 cells, to explore the mechanisms of the inhibitory effect of baicalin on iron accumulation observed in Parkinson＇s disease rats. Iron content was detected using inductively coupled plasma-atomic emission spectroscopy. Results showed that iron content decreased 41% after blocking divalent metal transporter 1 and ferroportin 1 proteins. After treatment with ferric ammonium citrate of differing concentrations （10, 50, 100, 400 ktg/mL） in C6 glioma cells, cell survival rate and ferroportin 1 expression were negatively correlated with ferric ammonium citrate concentration, but divalent metal transporter 1 expression positively correlated with ferric ammonium citrate concentration. Baicalin or deferoxamine reduced divalent metal transporter 1 expression, but increased ferroportin 1 expression in the 100 μg/mL ferric ammonium citrate-loaded C6 cells. These results indicate that baicalin down-regulated iron concentration, which positively regulat- ed divalent metal transporter 1 expression and negatively regulated ferroportin 1 expression, and decreased iron accumulation in the substantia nigra.

Seven Research Projects Sponsored by the 973 Program and the Major Research Plan

China＇s Ministry of Science and Technology recently announced approval of China＇s National Basic Research Program （the 973 Program） and the Major Research Plan projects in 2008. Five Tsinghua research projects will be sponsored by the 973 Program and two by the Major Research Plan. Seven professors were appointed as chief scientists for the projects. Tsinghua has undertaken 28 projects since the 973 Program＇s inception involving 28 chief scientists and eight Major Research Plan projects involving eight chief scientists. Tsinghua is one of the country＇s leading institutions for supervision and conduct of the 973 Program projects.

Research Priorities and Drilling Goals of Ocean Drilling Program

The research priorities and drilling goals of Ocean Drilling Program are introduced from two scientific themes. The scientific theme of dynamics of earth’s environment try to understand earth’s changing climate, causes and effects of sea—level change, and other problems such as global carbon cycle, formation of gas hydrates and submarine