Reproductive immunology is a crossed subject of reproductive biology and immunobiology. Great progresses have been achieved in the subject along with the deep development in life science. Modern reproductive immunolog...Reproductive immunology is a crossed subject of reproductive biology and immunobiology. Great progresses have been achieved in the subject along with the deep development in life science. Modern reproductive immunology includes immunological regulation of fertility, materno-fetal immuno-regu-lation, and neuro-reproductive endocrino-immune network. With the integrated traditional Chinese and western medicine (ICWM) applied to reproductive immunology it has been greatly enriched in research contents and depth. The present review is to introduce the recent progresses in research of integrated medicine on reproductive immunology.展开更多
This paper is the analysis of the main body, the object and their relationship concerning research of traditional Chinese medicine. The result proved that the main body of research of traditional Chinese medicine is r...This paper is the analysis of the main body, the object and their relationship concerning research of traditional Chinese medicine. The result proved that the main body of research of traditional Chinese medicine is researchers who possessed the fundamentals of traditional Chinese medicine. It is the objects of research of traditional Chinese medicine that origin of a class of traditional Chinese medical literature consisting of herbals which focus on descriptions of individual drugs; the relationship of the technological process of preparing Chinese medicine, as by parching, roasting, baking, steaming, soaking, and simmering, etc.;and technology of separating, extracting and purifying for composition; traditional Chinese medicine dynamics of one of the 12 two-hour periods into which the day was formerly divided before the introduction of western chronology; compatibility of medicines in active compositions; patent, effectiveness for a given period of time and constantly changing of traditional Chinese medicine.The relationship between the main body and the objects was that the former depends on the latter ones and the main body has subjective initiative as fully as possible.展开更多
Research into anticancer substances madefrom Chinese herbal drugs and their clinicalapplication is gaining international attention bythe medical profession of the more than 20analogues of camptothecine isolated from C...Research into anticancer substances madefrom Chinese herbal drugs and their clinicalapplication is gaining international attention bythe medical profession of the more than 20analogues of camptothecine isolated from Camp-totheca tree in China, most exhibited anticanceractivity. Among them, 10-hydroxycamptothe-cine has a wide anticancer spectrum and is lesstoxic. In suspension, it exhibits some therapeu-tic effects on primary hepatic cancer, gastriccarcinoma, cancer of the urinary bladder andleukemia.展开更多
OBJECTIVE: To help researchers selecting appropriate data mining models to provide better evidence for the clinical practice of Traditional Chinese Medicine(TCM) diagnosis and therapy.METHODS: Clinical issues based on...OBJECTIVE: To help researchers selecting appropriate data mining models to provide better evidence for the clinical practice of Traditional Chinese Medicine(TCM) diagnosis and therapy.METHODS: Clinical issues based on data mining models were comprehensively summarized from four significant elements of the clinical studies:symptoms, symptom patterns, herbs, and efficacy.Existing problems were further generalized to determine the relevant factors of the performance of data mining models, e.g. data type, samples, parameters, variable labels. Combining these relevant factors, the TCM clinical data features were compared with regards to statistical characters and informatics properties. Data models were compared simultaneously from the view of applied conditions and suitable scopes.RESULTS: The main application problems were the inconsistent data type and the small samples for the used data mining models, which caused the inappropriate results, even the mistake results. These features, i.e. advantages, disadvantages, satisfied data types, tasks of data mining, and the TCM issues, were summarized and compared.CONCLUSION: By aiming at the special features of different data mining models, the clinical doctors could select the suitable data mining models to resolve the TCM problem.展开更多
Traditional Chinese medicines (TCMs) have been used in China for thousands of years for the treatment of various diseases, highly treated as the Chinese cultural heritage. It has played the pivotal role in maintaini...Traditional Chinese medicines (TCMs) have been used in China for thousands of years for the treatment of various diseases, highly treated as the Chinese cultural heritage. It has played the pivotal role in maintaining the health of Chinese people and even the entire globe.展开更多
Model organisms are the important part of modem life sciences. Arabidopsis thaliana, Oryza sativa, and other model plants have been widely applied in the field of plant science and agronomy, while the international st...Model organisms are the important part of modem life sciences. Arabidopsis thaliana, Oryza sativa, and other model plants have been widely applied in the field of plant science and agronomy, while the international studies on traditional medicine lack the model organisms. Salvia miltiorrhiza, a perennial herb, is one Of the most commonly used medicines.展开更多
Gastric dyskinesis functional dyspepsia is a commonly clinical condition characterized as epigastric discomfort,distension after meals,early satiety and belching,which are commonly associated with the dysfunction of g...Gastric dyskinesis functional dyspepsia is a commonly clinical condition characterized as epigastric discomfort,distension after meals,early satiety and belching,which are commonly associated with the dysfunction of gastrointestinal motility.展开更多
In this special issue of Research Progress on Traditional Chinese Medicine and Medicinal Resources,articles describing the current advances of research on traditional Chinese medicine(TCM)will be invited for submissio...In this special issue of Research Progress on Traditional Chinese Medicine and Medicinal Resources,articles describing the current advances of research on traditional Chinese medicine(TCM)will be invited for submission.The directions of submissions include but not limited to:1.The separation and identification of the chemical components of TCM,pharmacological展开更多
In this article I argue how in the history of philosophy the meaning of the term“to be”was disputed over by two research programmes:the Platonic-Aristotelian one up to Heidegger and the Pythagorean-Parmenidean-Democ...In this article I argue how in the history of philosophy the meaning of the term“to be”was disputed over by two research programmes:the Platonic-Aristotelian one up to Heidegger and the Pythagorean-Parmenidean-Democritean one through Hobbes and Boole up to Peano.I call the first of“grammatical”type,the other of“linguistic algebraic”type.As in the grammatical classifications,in the former,formal or linguistic distinctions are mistaken for distinctions of logical type,or even of real or,as it is said,metaphysical type;hence its empty philosophical verbalism.In the latter,the term“to be”is taken in its merely linguistic meaning to build the science of reality,which should be known starting from rational principles,the“ideas”,as Democritus called them,through an adequate language.展开更多
Chinese oncologists have made great progress on the prevention and treatment of tumor with the combined traditional Chinese medicine (TCM) and Western Medicine (WM). Combining TCM with WM features the cancer research ...Chinese oncologists have made great progress on the prevention and treatment of tumor with the combined traditional Chinese medicine (TCM) and Western Medicine (WM). Combining TCM with WM features the cancer research and control in China and has obtained world attention. Researches on cancer prevention with TCM. According to the theories of TCM, cancer is the result of the long-term action of carcinogenic factors under the condition of "Internal Insufficiency" of the body. Some chronic inflammatory changes could cause epithelial cell proliferation and malignant changes. Consequently, TCM treatment for precancerous lesions is very important. The interrup tion effect of Liuwei Dihuang decoction (六味地汤) in severe epithelial atypical hyperplasia of展开更多
As one of the significant parts of medical science research in China,the research on Chinese medicine(CM) reflects the essence of healthcare tradition in the country both theoretically and clinically, and embodies t...As one of the significant parts of medical science research in China,the research on Chinese medicine(CM) reflects the essence of healthcare tradition in the country both theoretically and clinically, and embodies the values of Chinese culture.Therefore,in the practice of ethics review on CM research protocols,besides abiding by the contemporary prevalent international principles and guidelines on bioethics, which emphasizes the scientific and bioethical value of the study,we should also stress the CM theoretical background and relevant clinical experience in the framework of Chinese culture and values.In this paper, we went over the traits of CM clinical research and the experience from the practice of ethics review by the institution review board for bioethics,and then attempted to summarize the key points for the bioethics review to CM researches in China,so as to serve as reference for the bioethics review to traditional and alternative medicine researches.展开更多
A post-marketing study is an integral part of research that helps to ensure a favorable risk-benefit profile for approved drugs used in the market. Because most of post-marketing studies use observational designs, whi...A post-marketing study is an integral part of research that helps to ensure a favorable risk-benefit profile for approved drugs used in the market. Because most of post-marketing studies use observational designs, which are liable to confounding, estimation of the causal effect of a drug versus a comparative one is very challenging. This article focuses on methodological issues of importance in designing and analyzing studies to evaluate the safety of marketed drugs, especially marketed traditional Chinese medicine (TCM) products. Advantages and limitations of the current designs and analytic methods for postmarketing studies are discussed, and recommendations are given for improving the validity of postmarketing studies in TCM products.展开更多
文摘Reproductive immunology is a crossed subject of reproductive biology and immunobiology. Great progresses have been achieved in the subject along with the deep development in life science. Modern reproductive immunology includes immunological regulation of fertility, materno-fetal immuno-regu-lation, and neuro-reproductive endocrino-immune network. With the integrated traditional Chinese and western medicine (ICWM) applied to reproductive immunology it has been greatly enriched in research contents and depth. The present review is to introduce the recent progresses in research of integrated medicine on reproductive immunology.
文摘This paper is the analysis of the main body, the object and their relationship concerning research of traditional Chinese medicine. The result proved that the main body of research of traditional Chinese medicine is researchers who possessed the fundamentals of traditional Chinese medicine. It is the objects of research of traditional Chinese medicine that origin of a class of traditional Chinese medical literature consisting of herbals which focus on descriptions of individual drugs; the relationship of the technological process of preparing Chinese medicine, as by parching, roasting, baking, steaming, soaking, and simmering, etc.;and technology of separating, extracting and purifying for composition; traditional Chinese medicine dynamics of one of the 12 two-hour periods into which the day was formerly divided before the introduction of western chronology; compatibility of medicines in active compositions; patent, effectiveness for a given period of time and constantly changing of traditional Chinese medicine.The relationship between the main body and the objects was that the former depends on the latter ones and the main body has subjective initiative as fully as possible.
文摘Research into anticancer substances madefrom Chinese herbal drugs and their clinicalapplication is gaining international attention bythe medical profession of the more than 20analogues of camptothecine isolated from Camp-totheca tree in China, most exhibited anticanceractivity. Among them, 10-hydroxycamptothe-cine has a wide anticancer spectrum and is lesstoxic. In suspension, it exhibits some therapeu-tic effects on primary hepatic cancer, gastriccarcinoma, cancer of the urinary bladder andleukemia.
基金Supported by Research on Pattern differentiation of AIDS based on Graph Theroy of National Natural Science Foundation of China(No.81202858)Research on Intervention Evaluation of TCM Health Differentiation of National Key Technology Support Program(No.2012BAI25B02)+3 种基金Research and Development in Digital Information System of Traditional Chinese Medicine of National 863 Program of China(No.2012AA02A609)Acupuncture Efficacy of Gastrointestinal Dysfunction(No.ZZ05003)Acupuncture-point Specialty Analysis based on Image Processing Technology(No.ZZ03090)of Self-selected subject of China Academy of Chinese Medical SciencesSemantic Recognition of Tongue and Pulse based on Image Content of the Beijing Key Laboratory of Advanced Information Science and Network Technology(No.XDXX1306)
文摘OBJECTIVE: To help researchers selecting appropriate data mining models to provide better evidence for the clinical practice of Traditional Chinese Medicine(TCM) diagnosis and therapy.METHODS: Clinical issues based on data mining models were comprehensively summarized from four significant elements of the clinical studies:symptoms, symptom patterns, herbs, and efficacy.Existing problems were further generalized to determine the relevant factors of the performance of data mining models, e.g. data type, samples, parameters, variable labels. Combining these relevant factors, the TCM clinical data features were compared with regards to statistical characters and informatics properties. Data models were compared simultaneously from the view of applied conditions and suitable scopes.RESULTS: The main application problems were the inconsistent data type and the small samples for the used data mining models, which caused the inappropriate results, even the mistake results. These features, i.e. advantages, disadvantages, satisfied data types, tasks of data mining, and the TCM issues, were summarized and compared.CONCLUSION: By aiming at the special features of different data mining models, the clinical doctors could select the suitable data mining models to resolve the TCM problem.
文摘Traditional Chinese medicines (TCMs) have been used in China for thousands of years for the treatment of various diseases, highly treated as the Chinese cultural heritage. It has played the pivotal role in maintaining the health of Chinese people and even the entire globe.
文摘Model organisms are the important part of modem life sciences. Arabidopsis thaliana, Oryza sativa, and other model plants have been widely applied in the field of plant science and agronomy, while the international studies on traditional medicine lack the model organisms. Salvia miltiorrhiza, a perennial herb, is one Of the most commonly used medicines.
文摘Gastric dyskinesis functional dyspepsia is a commonly clinical condition characterized as epigastric discomfort,distension after meals,early satiety and belching,which are commonly associated with the dysfunction of gastrointestinal motility.
文摘In this special issue of Research Progress on Traditional Chinese Medicine and Medicinal Resources,articles describing the current advances of research on traditional Chinese medicine(TCM)will be invited for submission.The directions of submissions include but not limited to:1.The separation and identification of the chemical components of TCM,pharmacological
文摘In this article I argue how in the history of philosophy the meaning of the term“to be”was disputed over by two research programmes:the Platonic-Aristotelian one up to Heidegger and the Pythagorean-Parmenidean-Democritean one through Hobbes and Boole up to Peano.I call the first of“grammatical”type,the other of“linguistic algebraic”type.As in the grammatical classifications,in the former,formal or linguistic distinctions are mistaken for distinctions of logical type,or even of real or,as it is said,metaphysical type;hence its empty philosophical verbalism.In the latter,the term“to be”is taken in its merely linguistic meaning to build the science of reality,which should be known starting from rational principles,the“ideas”,as Democritus called them,through an adequate language.
文摘Chinese oncologists have made great progress on the prevention and treatment of tumor with the combined traditional Chinese medicine (TCM) and Western Medicine (WM). Combining TCM with WM features the cancer research and control in China and has obtained world attention. Researches on cancer prevention with TCM. According to the theories of TCM, cancer is the result of the long-term action of carcinogenic factors under the condition of "Internal Insufficiency" of the body. Some chronic inflammatory changes could cause epithelial cell proliferation and malignant changes. Consequently, TCM treatment for precancerous lesions is very important. The interrup tion effect of Liuwei Dihuang decoction (六味地汤) in severe epithelial atypical hyperplasia of
基金Supported by the Major Projects of National Science and Technology"Research Project Technology Platform for Clinical Evaluation of New Drugs of Chinese Medicine"(No. 2008ZX09312-021)
文摘As one of the significant parts of medical science research in China,the research on Chinese medicine(CM) reflects the essence of healthcare tradition in the country both theoretically and clinically, and embodies the values of Chinese culture.Therefore,in the practice of ethics review on CM research protocols,besides abiding by the contemporary prevalent international principles and guidelines on bioethics, which emphasizes the scientific and bioethical value of the study,we should also stress the CM theoretical background and relevant clinical experience in the framework of Chinese culture and values.In this paper, we went over the traits of CM clinical research and the experience from the practice of ethics review by the institution review board for bioethics,and then attempted to summarize the key points for the bioethics review to CM researches in China,so as to serve as reference for the bioethics review to traditional and alternative medicine researches.
基金Supported by the Research on Key Techniques of Reevaluation of Post-marketing Chinese Medicine,the Ministry of Science and Technology(No.2009ZX09502-030)the Sixth-Science Foundation of Institute of Basic Research in Clinical Medicine,China Academy of Chinese Medical Sciences(Grant No.Z0215)the Seventh-Science Foundation of Institute of Basic Research in Clinical Medicine,China Academy of Chinese Medical Sciences(Grant No.Z0255)
文摘A post-marketing study is an integral part of research that helps to ensure a favorable risk-benefit profile for approved drugs used in the market. Because most of post-marketing studies use observational designs, which are liable to confounding, estimation of the causal effect of a drug versus a comparative one is very challenging. This article focuses on methodological issues of importance in designing and analyzing studies to evaluate the safety of marketed drugs, especially marketed traditional Chinese medicine (TCM) products. Advantages and limitations of the current designs and analytic methods for postmarketing studies are discussed, and recommendations are given for improving the validity of postmarketing studies in TCM products.