Purpose:The goal of this study is a comparative analysis of the relation between funding(a main driver for scientific research)and citations in papers of Nobel Laureates in physics,chemistry and medicine over 2019-202...Purpose:The goal of this study is a comparative analysis of the relation between funding(a main driver for scientific research)and citations in papers of Nobel Laureates in physics,chemistry and medicine over 2019-2020 and the same relation in these research fields as a whole.Design/methodology/approach:This study utilizes a power law model to explore the relationship between research funding and citations of related papers.The study here analyzes 3,539 recorded documents by Nobel Laureates in physics,chemistry and medicine and a broader dataset of 183,016 documents related to the fields of physics,medicine,and chemistry recorded in the Web of Science database.Findings:Results reveal that in chemistry and medicine,funded researches published in papers of Nobel Laureates have higher citations than unfunded studies published in articles;vice versa high citations of Nobel Laureates in physics are for unfunded studies published in papers.Instead,when overall data of publications and citations in physics,chemistry and medicine are analyzed,all papers based on funded researches show higher citations than unfunded ones.Originality/value:Results clarify the driving role of research funding for science diffusion that are systematized in general properties:a)articles concerning funded researches receive more citations than(un)funded studies published in papers of physics,chemistry and medicine sciences,generating a high Matthew effect(a higher growth of citations with the increase in the number of papers);b)research funding increases the citations of articles in fields oriented to applied research(e.g.,chemistry and medicine)more than fields oriented towards basic research(e.g.,physics).Practical implications:The results here explain some characteristics of scientific development and diffusion,highlighting the critical role of research funding in fostering citations and the expansion of scientific knowledge.This finding can support decision-making of policymakers and R&D managers to improve the effectiveness in allocating financial resources in science policies to generate a higher positive scientific and societal impact.展开更多
Diabetic eye disease refers to a group of eye complications that occur in diabetic patients and include diabetic retinopathy, diabetic macular edema, diabetic cataracts, and diabetic glaucoma. However, the global epid...Diabetic eye disease refers to a group of eye complications that occur in diabetic patients and include diabetic retinopathy, diabetic macular edema, diabetic cataracts, and diabetic glaucoma. However, the global epidemiology of these conditions has not been well characterized. In this study, we collected information on diabetic eye disease-related research grants from seven representative countries––the United States, China, Japan, the United Kingdom, Spain, Germany, and France––by searching for all global diabetic eye disease journal articles in the Web of Science and Pub Med databases, all global registered clinical trials in the Clinical Trials database, and new drugs approved by the United States, China, Japan, and EU agencies from 2012 to 2021. During this time period, diabetic retinopathy accounted for the vast majority(89.53%) of the 2288 government research grants that were funded to investigate diabetic eye disease, followed by diabetic macular edema(9.27%). The United States granted the most research funding for diabetic eye disease out of the seven countries assessed. The research objectives of grants focusing on diabetic retinopathy and diabetic macular edema differed by country. Additionally, the United States was dominant in terms of research output, publishing 17.53% of global papers about diabetic eye disease and receiving 22.58% of total citations. The United States and the United Kingdom led international collaborations in research into diabetic eye disease. Of the 415 clinical trials that we identified, diabetic macular edema was the major disease that was targeted for drug development(58.19%). Approximately half of the trials(49.13%) pertained to angiogenesis. However, few drugs were approved for ophthalmic(40 out of 1830;2.19%) and diabetic eye disease(3 out of 1830;0.02%) applications. Our findings show that basic and translational research related to diabetic eye disease in the past decade has not been highly active, and has yielded few new treatment methods and newly approved drugs.展开更多
Professor Konstantin Chingin is engaged in the research of direct mass spectrum analysis in terms of basic theories,instrument development and applications and has achieved plenty of original results. He has done a lo...Professor Konstantin Chingin is engaged in the research of direct mass spectrum analysis in terms of basic theories,instrument development and applications and has achieved plenty of original results. He has done a lot in the fields of scientific research, platform construction。展开更多
Purpose:Assess whether ChatGPT 4.0 is accurate enough to perform research evaluations on journal articles to automate this time-consuming task.Design/methodology/approach:Test the extent to which ChatGPT-4 can assess ...Purpose:Assess whether ChatGPT 4.0 is accurate enough to perform research evaluations on journal articles to automate this time-consuming task.Design/methodology/approach:Test the extent to which ChatGPT-4 can assess the quality of journal articles using a case study of the published scoring guidelines of the UK Research Excellence Framework(REF)2021 to create a research evaluation ChatGPT.This was applied to 51 of my own articles and compared against my own quality judgements.Findings:ChatGPT-4 can produce plausible document summaries and quality evaluation rationales that match the REF criteria.Its overall scores have weak correlations with my self-evaluation scores of the same documents(averaging r=0.281 over 15 iterations,with 8 being statistically significantly different from 0).In contrast,the average scores from the 15 iterations produced a statistically significant positive correlation of 0.509.Thus,averaging scores from multiple ChatGPT-4 rounds seems more effective than individual scores.The positive correlation may be due to ChatGPT being able to extract the author’s significance,rigour,and originality claims from inside each paper.If my weakest articles are removed,then the correlation with average scores(r=0.200)falls below statistical significance,suggesting that ChatGPT struggles to make fine-grained evaluations.Research limitations:The data is self-evaluations of a convenience sample of articles from one academic in one field.Practical implications:Overall,ChatGPT does not yet seem to be accurate enough to be trusted for any formal or informal research quality evaluation tasks.Research evaluators,including journal editors,should therefore take steps to control its use.Originality/value:This is the first published attempt at post-publication expert review accuracy testing for ChatGPT.展开更多
This article is a case study of an innovative academic health sciences library initiative that describes the planning and events in the inaugural year of a new library research program. In response to emerging trends ...This article is a case study of an innovative academic health sciences library initiative that describes the planning and events in the inaugural year of a new library research program. In response to emerging trends in health sciences libraries to increase research skills of librarians in order to foster expanded research integration within the health sciences disciplines,the University of Michigan Taubman Health Sciences Library established an EXPERT Research Initiative. This new program is part of the strategic planning for the future of the library and is focused on three primary goals: expanding the library's research portfolio,building librarians' research skills and competencies,and increasing the library's research visibility. The article highlights five library projects that illustrate the different kinds of research collaborations librarians are engaged in with health sciences faculty,researchers,clinicians,and students.展开更多
In this paper,substantial domestic and foreign research results of microscopic shale reservoir space were systemically reviewed,the research history consisting of simple observation and qualitative classification,quan...In this paper,substantial domestic and foreign research results of microscopic shale reservoir space were systemically reviewed,the research history consisting of simple observation and qualitative classification,quantitative research,the combination of qualitative and quantitative research successively as well as the characteristics of each research stage were summarized.In addition,the current problems existing in the characterization methods of shale reservoir space were also analyzed.Furthermore,based on massive actual detection of typical core samples obtained from more than 50 global shale gas wells and relevant practical experience,a comprehensive characterization method of combining qualitative with the semiquantitative characterization was put forward.In detail,the indicators of the qualitative characterization include pore combination type and organic-matter microscopic morphology type,while the core elements of the semi-quantitative characterization include the percentage of the organic-matter area and the plane porosity of the pores of different types.Based on the reference of the naming and classification of rocks,the three-end-member diagram method was used to characterize microscopic shale reservoir space.This is achieved by plotting the three end-member diagram of 3 kinds of first-order critical reservoir spaces,i.e.,organic-matter pores,matrix pores,and micro-fractures,in order to intuitively present the features of the microscopic pore combination.Meanwhile,statistic histograms of organic-matter microscopic morphology type and the plane porosity of different types of pores were adopted to characterize the development degree of second-order pores quantitatively.By this comprehensive characterization method,the importance of both pore combination and the microscopic morphology of organic matter were emphasized,revealing the control of organic-matter microscopic morphology over the organic-matter pores.What is more,high-resolution FE-SEM was adopted to obtain semi-quantitative statistics results.In this way,the features of pore development and pore combination were quantified,not only reflecting the types and storage capacity of the microscopic shale reservoir space,but also presenting the hydrocarbongenerating potential of organic matter in shale.Therefore,the results of this research are capable of providing in-depth microscopic information for the assessment and exploration and development of shale gas resources.展开更多
In Chinese language studies, both “The Textual Research on Historical Documents” and “The Comparative Study of Historical Data” are traditional in methodology and they both deserve being treasured, passed on, and ...In Chinese language studies, both “The Textual Research on Historical Documents” and “The Comparative Study of Historical Data” are traditional in methodology and they both deserve being treasured, passed on, and further developed. It will certainly do harm to the development of academic research if any of the two methods is given unreasonable priority. The author claims that the best or one of the best methodologies of the historical study of Chinese language is the combination of the two, hence a new interpretation of “The Double-proof Method”. Meanwhile, this essay is also an attempt to put forward “The Law of Quan-ma and Gui-mei” in Chinese language studies, in which the author believes that it is not advisable to either treat Gui-mei as Quan-ma or vice versa in linguistic research. It is crucial for us to respect always the language facts first, which is considered the very soul of linguistics.展开更多
BACKGROUND Overweight/obesity combined with depression among children and adolescents(ODCA)is a global concern.The bidirectional relationship between depression and overweight/obesity often leads to their comorbidity....BACKGROUND Overweight/obesity combined with depression among children and adolescents(ODCA)is a global concern.The bidirectional relationship between depression and overweight/obesity often leads to their comorbidity.Childhood and adolescence represent critical periods for physical and psychological development,during which the comorbidity of overweight/obesity and depression may increase the risk of adverse health outcomes.AIM To evaluate the relationship between ODCA,we conduct a bibliometric analysis to aid in formulating prevention and treatment strategies.METHODS From 2004 to 2023,articles related to ODCA were selected using the Science Citation Index Expanded from the Web of Science Core Collection.Bibliometric analysis of relevant publications,including countries/regions,institutions,authors,journals,references,and keywords,was conducted using the online bibliometric analysis platforms,CiteSpace,VOSviewer,and bibliometrix.RESULTS Between 2004 and 2023,a total of 1573 articles were published on ODCA.The United States has made leading contributions in this field,with Harvard University emerging as the leading contributor in terms of research output,and Tanofsky being the most prolific author.The J Adolescent Health has shown significant activity in this domain.Based on the results of the keyword and reference analyses,inequality,adverse childhood experiences,and comorbidities have become hot topics in ODCA.Moreover,the impact of balancedrelated behavior and exploration of the biological mechanisms,including the potential role of key adipocytokines and lipokines,as well as inflammation in ODCA,have emerged as frontier topics.CONCLUSION The trend of a significant increase in ODCA publications is expected to continue.The research findings will contribute to elucidating the pathogenic mechanisms of ODCA and its prevention and treatment.展开更多
The importance and utility of biobanks has increased exponentially since their inception and creation.Initially used as part of translational research,they now contribute over 40%of data for all cancer research papers...The importance and utility of biobanks has increased exponentially since their inception and creation.Initially used as part of translational research,they now contribute over 40%of data for all cancer research papers in the United States of America and play a crucial role in all aspects of healthcare.Multiple classification systems exist but a simplified approach is to either classify as population-based or disease-oriented entities.Whilst historically publicly funded institutions,there has been a significant increase in industry funded entities across the world which has changed the dynamic of biobanks offering new possibilities but also new challenges.Biobanks face legal questions over data sharing and intellectual property as well as ethical and sustainability questions particularly as the world attempts to move to a low-carbon economy.International collaboration is required to address some of these challenges but this in itself is fraught with complexity and difficulty.This review will examine the current utility of biobanks in the modern healthcare setting as well as the current and future challenges these vital institutions face.展开更多
We associate a variety of innovations with the term "Industry 4.0". The pioneer of many 4.0 modifications forms the basisfor the trend towards the integrated digitization of many areas of life. The field of research...We associate a variety of innovations with the term "Industry 4.0". The pioneer of many 4.0 modifications forms the basisfor the trend towards the integrated digitization of many areas of life. The field of research requires from the pilot plants to developnew pioneering fibers high flexibility of its experimental facilities to allow new insights in the laboratory and prototype facilities at areasonable cost. Added to this is the desire to closely track all process data and prepare it in a timely manner. Mobile devices nowallow the researcher to vary parameters close to the process during observation. In the following lecture the question will bediscussed which of the many definitions and varieties of "Industry 4.0" can be meaningfully transferred to the field of research. Indoing so, we are guided by the findings that have been gained with modularized spinning systems in recent years. The respectivespinning processes require different analysis focuses and different conversion options. The digital world must follow the realdemands of the analog world. In addition to the elegance functions, it must be ensured that the control functions of the process meetthe requirements of machine safety. Digitization allows intelligent analyzes to be developed independently of the various spinningprocesses and can be flexibly adapted to the respective process conditions. The variability of spin systems depends on the intelligentmodularization of individual functions and the physics that require the spinning conditions. Finally, some examples of modularprototype systems are presented, and the limits of variability are discussed.展开更多
The Sun et al's training program for clinical research nurses(CRNs)in the World Journal of Clinical Cases is a comprehensive and scientific approach.It includes structured frameworks for CRN training,aiming to imp...The Sun et al's training program for clinical research nurses(CRNs)in the World Journal of Clinical Cases is a comprehensive and scientific approach.It includes structured frameworks for CRN training,aiming to improve CRN competency.This program emphasizes practical abilities,updates training content,and improves evaluation methods.The cultivation of CRN talents focuses on enhancing the training system,establishing a multifaceted evaluation framework,and continuously refining the training programs.Regular feedback and evalua-tion are essential to improve CRNs'competency in practical settings.展开更多
Conventional dentistry or periodontal research often ignores the human component in favor of clinical outcomes and biological causes.Clinical research is driven by the statistical significance of outcome parameters ra...Conventional dentistry or periodontal research often ignores the human component in favor of clinical outcomes and biological causes.Clinical research is driven by the statistical significance of outcome parameters rather than the satisfaction level of the patient.In this context,patient-centric periodontal research(PCPR)is an approach that considers the patient´s feedback concerning their functional status,experience,clinical outcomes,and accessibility to their treatments.It is argued that data self-reported by the patient might have low reliability owing to the confounding effect of their personal belief,cultural background,and social and economic factors.However,literature has shown that the incorporation of“patient-centric outcome”components considerably enhances the validity and applicability of research findings.Variations in the results of different studies might be due to the use of different and non-standardized assessment tools.To overcome this problem,this editorial enlists various reliable tools available in the literature.In conclusion,we advocate that the focus of researchers should shift from mere periodontal research to PCPR so that the results can be effectively applied in clinical settings and the therapeutic strategy can also change from mere periodontal therapy to patient-centric periodontal therapy.展开更多
The landscape environment of urban blocks plays a significant role in improving the comfort of urban thermal environment and promoting green and high-quality development.The 342 papers related to the research on the i...The landscape environment of urban blocks plays a significant role in improving the comfort of urban thermal environment and promoting green and high-quality development.The 342 papers related to the research on the impact of urban block landscape environment on thermal comfort in China,collected by CNKI(China National Knowledge Infrastructure)from 2002 to 2022,are used as the research object.Through bibliometric statistical analysis,LLR algorithm,and cluster analysis,the current research status of the impact of urban block landscape environment on thermal comfort in China is analyzed and processed,and its external characteristics are identified.Using the information visualization software CiteSpace,the research topics in the field of the impact of urban block landscape environment on thermal comfort are presented in the form of knowledge graphs.Through co-occurrence analysis of keywords and trend of word frequency changes,the development trends of research hotspots and cutting-edge fields of the impact of urban block landscape environment on thermal comfort are determined,hoping to provide reference for future research in this field.展开更多
The integration of Artificial Intelligence(AI)into healthcare research promises unprecedented advancements in medical diagnostics,treatment personalization,and patient care management.However,these innovations also br...The integration of Artificial Intelligence(AI)into healthcare research promises unprecedented advancements in medical diagnostics,treatment personalization,and patient care management.However,these innovations also bring forth significant ethical challenges that must be addressed to maintain public trust,ensure patient safety,and uphold data integrity.This article sets out to introduce a detailed framework designed to steer governance and offer a systematic method for assuring that AI applications in healthcare research are developed and executed with integrity and adherence to medical research ethics.展开更多
This study explored and reviewed the logistic regression (LR) model, a multivariable method for modeling the relationship between multiple independent variables and a categorical dependent variable, with emphasis on m...This study explored and reviewed the logistic regression (LR) model, a multivariable method for modeling the relationship between multiple independent variables and a categorical dependent variable, with emphasis on medical research. Thirty seven research articles published between 2000 and 2018 which employed logistic regression as the main statistical tool as well as six text books on logistic regression were reviewed. Logistic regression concepts such as odds, odds ratio, logit transformation, logistic curve, assumption, selecting dependent and independent variables, model fitting, reporting and interpreting were presented. Upon perusing the literature, considerable deficiencies were found in both the use and reporting of LR. For many studies, the ratio of the number of outcome events to predictor variables (events per variable) was sufficiently small to call into question the accuracy of the regression model. Also, most studies did not report on validation analysis, regression diagnostics or goodness-of-fit measures;measures which authenticate the robustness of the LR model. Here, we demonstrate a good example of the application of the LR model using data obtained on a cohort of pregnant women and the factors that influence their decision to opt for caesarean delivery or vaginal birth. It is recommended that researchers should be more rigorous and pay greater attention to guidelines concerning the use and reporting of LR models.展开更多
There is an urgent need for high-quality talents with ideological and moral character for the development of higher education and the cultivation of English majors who meet the requirements of the times.The course ref...There is an urgent need for high-quality talents with ideological and moral character for the development of higher education and the cultivation of English majors who meet the requirements of the times.The course reform in English majors from the ideological and political perspective is an important way to improve the comprehensive quality and moral values of students,which helps to cultivate English talents with social responsibility and innovative abilities.This paper analyzes the problems in the current courses through literature review and field research,such as the lack of ideological and political perspective and low interest of students in ideological and political content.Based on these issues,taking the course“Comprehensive English”as an example,various teaching stages were practiced from the aspects of learning objectives,learning content,learning situation,implementation ideas,implementation effects,and teaching evaluation.Additionally,some suggestions are proposed,such as integrating ideological and political content into the entire process of teaching.The teaching staff needs to possess high-level English teaching ability and ideological and political perspective,standardize the evaluation system,and integrate epistemology into the evaluation process of ideological and political education,in order to promote in-depth research and exploration of ideological and political education of English majors.展开更多
Percutaneous coronary intervention(PCI)is an effective treatment method for myocardial ischemic necrosis.Postoperative depression caused by PCI stress will adversely affect the prognosis of patients.This article revie...Percutaneous coronary intervention(PCI)is an effective treatment method for myocardial ischemic necrosis.Postoperative depression caused by PCI stress will adversely affect the prognosis of patients.This article reviews the current status and influencing factors of postoperative depression after PCI and summarizes the corresponding nursing interventions,to provide a literature reference to implement effective nursing interventions for depressed patients after clinical PCI.展开更多
文摘Purpose:The goal of this study is a comparative analysis of the relation between funding(a main driver for scientific research)and citations in papers of Nobel Laureates in physics,chemistry and medicine over 2019-2020 and the same relation in these research fields as a whole.Design/methodology/approach:This study utilizes a power law model to explore the relationship between research funding and citations of related papers.The study here analyzes 3,539 recorded documents by Nobel Laureates in physics,chemistry and medicine and a broader dataset of 183,016 documents related to the fields of physics,medicine,and chemistry recorded in the Web of Science database.Findings:Results reveal that in chemistry and medicine,funded researches published in papers of Nobel Laureates have higher citations than unfunded studies published in articles;vice versa high citations of Nobel Laureates in physics are for unfunded studies published in papers.Instead,when overall data of publications and citations in physics,chemistry and medicine are analyzed,all papers based on funded researches show higher citations than unfunded ones.Originality/value:Results clarify the driving role of research funding for science diffusion that are systematized in general properties:a)articles concerning funded researches receive more citations than(un)funded studies published in papers of physics,chemistry and medicine sciences,generating a high Matthew effect(a higher growth of citations with the increase in the number of papers);b)research funding increases the citations of articles in fields oriented to applied research(e.g.,chemistry and medicine)more than fields oriented towards basic research(e.g.,physics).Practical implications:The results here explain some characteristics of scientific development and diffusion,highlighting the critical role of research funding in fostering citations and the expansion of scientific knowledge.This finding can support decision-making of policymakers and R&D managers to improve the effectiveness in allocating financial resources in science policies to generate a higher positive scientific and societal impact.
基金supported by the National Natural Science Foundation of China,No.82122009 (to JX)Science Research Foundation ofAier Eye Hospital Group,No.AM2001D1 (to JX)the Natural Science Foundation of Hunan Province,No.2020JJ5002 (to SJ)。
文摘Diabetic eye disease refers to a group of eye complications that occur in diabetic patients and include diabetic retinopathy, diabetic macular edema, diabetic cataracts, and diabetic glaucoma. However, the global epidemiology of these conditions has not been well characterized. In this study, we collected information on diabetic eye disease-related research grants from seven representative countries––the United States, China, Japan, the United Kingdom, Spain, Germany, and France––by searching for all global diabetic eye disease journal articles in the Web of Science and Pub Med databases, all global registered clinical trials in the Clinical Trials database, and new drugs approved by the United States, China, Japan, and EU agencies from 2012 to 2021. During this time period, diabetic retinopathy accounted for the vast majority(89.53%) of the 2288 government research grants that were funded to investigate diabetic eye disease, followed by diabetic macular edema(9.27%). The United States granted the most research funding for diabetic eye disease out of the seven countries assessed. The research objectives of grants focusing on diabetic retinopathy and diabetic macular edema differed by country. Additionally, the United States was dominant in terms of research output, publishing 17.53% of global papers about diabetic eye disease and receiving 22.58% of total citations. The United States and the United Kingdom led international collaborations in research into diabetic eye disease. Of the 415 clinical trials that we identified, diabetic macular edema was the major disease that was targeted for drug development(58.19%). Approximately half of the trials(49.13%) pertained to angiogenesis. However, few drugs were approved for ophthalmic(40 out of 1830;2.19%) and diabetic eye disease(3 out of 1830;0.02%) applications. Our findings show that basic and translational research related to diabetic eye disease in the past decade has not been highly active, and has yielded few new treatment methods and newly approved drugs.
文摘Professor Konstantin Chingin is engaged in the research of direct mass spectrum analysis in terms of basic theories,instrument development and applications and has achieved plenty of original results. He has done a lot in the fields of scientific research, platform construction。
文摘Purpose:Assess whether ChatGPT 4.0 is accurate enough to perform research evaluations on journal articles to automate this time-consuming task.Design/methodology/approach:Test the extent to which ChatGPT-4 can assess the quality of journal articles using a case study of the published scoring guidelines of the UK Research Excellence Framework(REF)2021 to create a research evaluation ChatGPT.This was applied to 51 of my own articles and compared against my own quality judgements.Findings:ChatGPT-4 can produce plausible document summaries and quality evaluation rationales that match the REF criteria.Its overall scores have weak correlations with my self-evaluation scores of the same documents(averaging r=0.281 over 15 iterations,with 8 being statistically significantly different from 0).In contrast,the average scores from the 15 iterations produced a statistically significant positive correlation of 0.509.Thus,averaging scores from multiple ChatGPT-4 rounds seems more effective than individual scores.The positive correlation may be due to ChatGPT being able to extract the author’s significance,rigour,and originality claims from inside each paper.If my weakest articles are removed,then the correlation with average scores(r=0.200)falls below statistical significance,suggesting that ChatGPT struggles to make fine-grained evaluations.Research limitations:The data is self-evaluations of a convenience sample of articles from one academic in one field.Practical implications:Overall,ChatGPT does not yet seem to be accurate enough to be trusted for any formal or informal research quality evaluation tasks.Research evaluators,including journal editors,should therefore take steps to control its use.Originality/value:This is the first published attempt at post-publication expert review accuracy testing for ChatGPT.
文摘This article is a case study of an innovative academic health sciences library initiative that describes the planning and events in the inaugural year of a new library research program. In response to emerging trends in health sciences libraries to increase research skills of librarians in order to foster expanded research integration within the health sciences disciplines,the University of Michigan Taubman Health Sciences Library established an EXPERT Research Initiative. This new program is part of the strategic planning for the future of the library and is focused on three primary goals: expanding the library's research portfolio,building librarians' research skills and competencies,and increasing the library's research visibility. The article highlights five library projects that illustrate the different kinds of research collaborations librarians are engaged in with health sciences faculty,researchers,clinicians,and students.
基金This study was supported by the National Scientific and Technological Major Special Project titled“Research on Evaluation Method and Exploration Technology on Shale Gas Resources”(2016ZX05034)“Shale Gas Basic Geological Survey Project in South China”(121201229000160021)initiated by CGSinter-governmental cooperation project titled“China-USA Cooperation Research Project of Carboniferous-Permian Shale Reservoir Evaluation Technology”(2017YFE0106300).
文摘In this paper,substantial domestic and foreign research results of microscopic shale reservoir space were systemically reviewed,the research history consisting of simple observation and qualitative classification,quantitative research,the combination of qualitative and quantitative research successively as well as the characteristics of each research stage were summarized.In addition,the current problems existing in the characterization methods of shale reservoir space were also analyzed.Furthermore,based on massive actual detection of typical core samples obtained from more than 50 global shale gas wells and relevant practical experience,a comprehensive characterization method of combining qualitative with the semiquantitative characterization was put forward.In detail,the indicators of the qualitative characterization include pore combination type and organic-matter microscopic morphology type,while the core elements of the semi-quantitative characterization include the percentage of the organic-matter area and the plane porosity of the pores of different types.Based on the reference of the naming and classification of rocks,the three-end-member diagram method was used to characterize microscopic shale reservoir space.This is achieved by plotting the three end-member diagram of 3 kinds of first-order critical reservoir spaces,i.e.,organic-matter pores,matrix pores,and micro-fractures,in order to intuitively present the features of the microscopic pore combination.Meanwhile,statistic histograms of organic-matter microscopic morphology type and the plane porosity of different types of pores were adopted to characterize the development degree of second-order pores quantitatively.By this comprehensive characterization method,the importance of both pore combination and the microscopic morphology of organic matter were emphasized,revealing the control of organic-matter microscopic morphology over the organic-matter pores.What is more,high-resolution FE-SEM was adopted to obtain semi-quantitative statistics results.In this way,the features of pore development and pore combination were quantified,not only reflecting the types and storage capacity of the microscopic shale reservoir space,but also presenting the hydrocarbongenerating potential of organic matter in shale.Therefore,the results of this research are capable of providing in-depth microscopic information for the assessment and exploration and development of shale gas resources.
文摘In Chinese language studies, both “The Textual Research on Historical Documents” and “The Comparative Study of Historical Data” are traditional in methodology and they both deserve being treasured, passed on, and further developed. It will certainly do harm to the development of academic research if any of the two methods is given unreasonable priority. The author claims that the best or one of the best methodologies of the historical study of Chinese language is the combination of the two, hence a new interpretation of “The Double-proof Method”. Meanwhile, this essay is also an attempt to put forward “The Law of Quan-ma and Gui-mei” in Chinese language studies, in which the author believes that it is not advisable to either treat Gui-mei as Quan-ma or vice versa in linguistic research. It is crucial for us to respect always the language facts first, which is considered the very soul of linguistics.
基金the National Natural Science Foundation of China,No.82074291the National Natural Science Foundation of China,No.8207153217+1 种基金the High-level Key Discipline of the National Administration of Traditional Chinese Medicine-Traditional Chinese Constitutional Medicine,No.zyyzdxk-2023251the Beijing University of Traditional Chinese Medicine Campus Level Project,No.90010961020140.
文摘BACKGROUND Overweight/obesity combined with depression among children and adolescents(ODCA)is a global concern.The bidirectional relationship between depression and overweight/obesity often leads to their comorbidity.Childhood and adolescence represent critical periods for physical and psychological development,during which the comorbidity of overweight/obesity and depression may increase the risk of adverse health outcomes.AIM To evaluate the relationship between ODCA,we conduct a bibliometric analysis to aid in formulating prevention and treatment strategies.METHODS From 2004 to 2023,articles related to ODCA were selected using the Science Citation Index Expanded from the Web of Science Core Collection.Bibliometric analysis of relevant publications,including countries/regions,institutions,authors,journals,references,and keywords,was conducted using the online bibliometric analysis platforms,CiteSpace,VOSviewer,and bibliometrix.RESULTS Between 2004 and 2023,a total of 1573 articles were published on ODCA.The United States has made leading contributions in this field,with Harvard University emerging as the leading contributor in terms of research output,and Tanofsky being the most prolific author.The J Adolescent Health has shown significant activity in this domain.Based on the results of the keyword and reference analyses,inequality,adverse childhood experiences,and comorbidities have become hot topics in ODCA.Moreover,the impact of balancedrelated behavior and exploration of the biological mechanisms,including the potential role of key adipocytokines and lipokines,as well as inflammation in ODCA,have emerged as frontier topics.CONCLUSION The trend of a significant increase in ODCA publications is expected to continue.The research findings will contribute to elucidating the pathogenic mechanisms of ODCA and its prevention and treatment.
文摘The importance and utility of biobanks has increased exponentially since their inception and creation.Initially used as part of translational research,they now contribute over 40%of data for all cancer research papers in the United States of America and play a crucial role in all aspects of healthcare.Multiple classification systems exist but a simplified approach is to either classify as population-based or disease-oriented entities.Whilst historically publicly funded institutions,there has been a significant increase in industry funded entities across the world which has changed the dynamic of biobanks offering new possibilities but also new challenges.Biobanks face legal questions over data sharing and intellectual property as well as ethical and sustainability questions particularly as the world attempts to move to a low-carbon economy.International collaboration is required to address some of these challenges but this in itself is fraught with complexity and difficulty.This review will examine the current utility of biobanks in the modern healthcare setting as well as the current and future challenges these vital institutions face.
文摘We associate a variety of innovations with the term "Industry 4.0". The pioneer of many 4.0 modifications forms the basisfor the trend towards the integrated digitization of many areas of life. The field of research requires from the pilot plants to developnew pioneering fibers high flexibility of its experimental facilities to allow new insights in the laboratory and prototype facilities at areasonable cost. Added to this is the desire to closely track all process data and prepare it in a timely manner. Mobile devices nowallow the researcher to vary parameters close to the process during observation. In the following lecture the question will bediscussed which of the many definitions and varieties of "Industry 4.0" can be meaningfully transferred to the field of research. Indoing so, we are guided by the findings that have been gained with modularized spinning systems in recent years. The respectivespinning processes require different analysis focuses and different conversion options. The digital world must follow the realdemands of the analog world. In addition to the elegance functions, it must be ensured that the control functions of the process meetthe requirements of machine safety. Digitization allows intelligent analyzes to be developed independently of the various spinningprocesses and can be flexibly adapted to the respective process conditions. The variability of spin systems depends on the intelligentmodularization of individual functions and the physics that require the spinning conditions. Finally, some examples of modularprototype systems are presented, and the limits of variability are discussed.
文摘The Sun et al's training program for clinical research nurses(CRNs)in the World Journal of Clinical Cases is a comprehensive and scientific approach.It includes structured frameworks for CRN training,aiming to improve CRN competency.This program emphasizes practical abilities,updates training content,and improves evaluation methods.The cultivation of CRN talents focuses on enhancing the training system,establishing a multifaceted evaluation framework,and continuously refining the training programs.Regular feedback and evalua-tion are essential to improve CRNs'competency in practical settings.
文摘Conventional dentistry or periodontal research often ignores the human component in favor of clinical outcomes and biological causes.Clinical research is driven by the statistical significance of outcome parameters rather than the satisfaction level of the patient.In this context,patient-centric periodontal research(PCPR)is an approach that considers the patient´s feedback concerning their functional status,experience,clinical outcomes,and accessibility to their treatments.It is argued that data self-reported by the patient might have low reliability owing to the confounding effect of their personal belief,cultural background,and social and economic factors.However,literature has shown that the incorporation of“patient-centric outcome”components considerably enhances the validity and applicability of research findings.Variations in the results of different studies might be due to the use of different and non-standardized assessment tools.To overcome this problem,this editorial enlists various reliable tools available in the literature.In conclusion,we advocate that the focus of researchers should shift from mere periodontal research to PCPR so that the results can be effectively applied in clinical settings and the therapeutic strategy can also change from mere periodontal therapy to patient-centric periodontal therapy.
基金the National Natural Science Foundation of China(51708004)Beijing Youth Teaching Master Team Construction Project(108051360023XN261)Yuyou Talent Training Program of North China University of Technology(215051360020XN160/009).
文摘The landscape environment of urban blocks plays a significant role in improving the comfort of urban thermal environment and promoting green and high-quality development.The 342 papers related to the research on the impact of urban block landscape environment on thermal comfort in China,collected by CNKI(China National Knowledge Infrastructure)from 2002 to 2022,are used as the research object.Through bibliometric statistical analysis,LLR algorithm,and cluster analysis,the current research status of the impact of urban block landscape environment on thermal comfort in China is analyzed and processed,and its external characteristics are identified.Using the information visualization software CiteSpace,the research topics in the field of the impact of urban block landscape environment on thermal comfort are presented in the form of knowledge graphs.Through co-occurrence analysis of keywords and trend of word frequency changes,the development trends of research hotspots and cutting-edge fields of the impact of urban block landscape environment on thermal comfort are determined,hoping to provide reference for future research in this field.
文摘The integration of Artificial Intelligence(AI)into healthcare research promises unprecedented advancements in medical diagnostics,treatment personalization,and patient care management.However,these innovations also bring forth significant ethical challenges that must be addressed to maintain public trust,ensure patient safety,and uphold data integrity.This article sets out to introduce a detailed framework designed to steer governance and offer a systematic method for assuring that AI applications in healthcare research are developed and executed with integrity and adherence to medical research ethics.
文摘This study explored and reviewed the logistic regression (LR) model, a multivariable method for modeling the relationship between multiple independent variables and a categorical dependent variable, with emphasis on medical research. Thirty seven research articles published between 2000 and 2018 which employed logistic regression as the main statistical tool as well as six text books on logistic regression were reviewed. Logistic regression concepts such as odds, odds ratio, logit transformation, logistic curve, assumption, selecting dependent and independent variables, model fitting, reporting and interpreting were presented. Upon perusing the literature, considerable deficiencies were found in both the use and reporting of LR. For many studies, the ratio of the number of outcome events to predictor variables (events per variable) was sufficiently small to call into question the accuracy of the regression model. Also, most studies did not report on validation analysis, regression diagnostics or goodness-of-fit measures;measures which authenticate the robustness of the LR model. Here, we demonstrate a good example of the application of the LR model using data obtained on a cohort of pregnant women and the factors that influence their decision to opt for caesarean delivery or vaginal birth. It is recommended that researchers should be more rigorous and pay greater attention to guidelines concerning the use and reporting of LR models.
文摘There is an urgent need for high-quality talents with ideological and moral character for the development of higher education and the cultivation of English majors who meet the requirements of the times.The course reform in English majors from the ideological and political perspective is an important way to improve the comprehensive quality and moral values of students,which helps to cultivate English talents with social responsibility and innovative abilities.This paper analyzes the problems in the current courses through literature review and field research,such as the lack of ideological and political perspective and low interest of students in ideological and political content.Based on these issues,taking the course“Comprehensive English”as an example,various teaching stages were practiced from the aspects of learning objectives,learning content,learning situation,implementation ideas,implementation effects,and teaching evaluation.Additionally,some suggestions are proposed,such as integrating ideological and political content into the entire process of teaching.The teaching staff needs to possess high-level English teaching ability and ideological and political perspective,standardize the evaluation system,and integrate epistemology into the evaluation process of ideological and political education,in order to promote in-depth research and exploration of ideological and political education of English majors.
基金Xianyang City Key R&D Plan Project(No.:L 2022ZDYFSF004)。
文摘Percutaneous coronary intervention(PCI)is an effective treatment method for myocardial ischemic necrosis.Postoperative depression caused by PCI stress will adversely affect the prognosis of patients.This article reviews the current status and influencing factors of postoperative depression after PCI and summarizes the corresponding nursing interventions,to provide a literature reference to implement effective nursing interventions for depressed patients after clinical PCI.