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Effect of Soy Isoflavone Crude Extract Supplementation on High Fat Diet-induced Insulin Resistance in Ovariectomized Rats 被引量:6
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作者 ZHANG Yun Bo LI Li Na +5 位作者 ZHAO Xin Yu CHEN Wen Hua GUO Jing Jing FU Zheng Hai YANG Yang NA Xiao Lin 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2014年第1期49-51,共3页
Female Wister rats aged 8 weeks were randomly divided into sham operation group, ovariectomized (OVX) control group, and 20VX groups fed with soy isoflavone crude extract supplementation. The rats had free access to... Female Wister rats aged 8 weeks were randomly divided into sham operation group, ovariectomized (OVX) control group, and 20VX groups fed with soy isoflavone crude extract supplementation. The rats had free access to high fat diet and water for 9 weeks. No significant difference was found in body weight (BW), total abdominal fat, food intake and food utilization rate between OVX control group and 20VX groups. However, the fasting blood glucose and blood lipid levels were significantly higher in 20VX groups than in OVX control group (P〈0.05). Intraperitoneal glucose tolerance test (IGTI") showed that the area under AUC was smaller in 20VX groups than in OVX control group (P〈0.05). These findings showed that soy isoflavone crude extract supplementation can improve glucose tolerance and prevent high fat diet-induced insulin resistance in ovariectomized rats. 展开更多
关键词 Effect of Soy Isoflavone Crude Extract Supplementation on High Fat Diet-induced Insulin Resistance in Ovariectomized Rats THAN
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