In this paper, we present an improved identity-based society oriented signature scheme with anonymous signers, which satisfies： （1） when members leave or join an organization, the public verification key and the si...In this paper, we present an improved identity-based society oriented signature scheme with anonymous signers, which satisfies： （1） when members leave or join an organization, the public verification key and the signature verification procedure are unchanged; （2） a user participates in several organizations at the same time, her secret key is only related with her identity. However, no previous schemes have these two properties.展开更多
Cervical cancer is the third most common cancer in women worldwide; definitive radiation therapy and concurrent chemotherapy is the accepted standard of care for patients with node positive or locally advanced tumors ...Cervical cancer is the third most common cancer in women worldwide; definitive radiation therapy and concurrent chemotherapy is the accepted standard of care for patients with node positive or locally advanced tumors > 4 cm. Brachytherapy is an important part of definitive radiotherapy shown to improve overall survival. While results for two-dimensional X-ray based brachytherapy have been good in terms of local control especially for early stage disease, unexplained toxicities and treatment failures remain. Improvements in brachytherapy planning have more recently paved the way for three-dimensional image-based brachytherapy with volumetric optimization which increases tumor control, reduces toxicity, and helps predict outcomes.Advantages of image-based brachytherapy include:improved tumor coverage(especially for large volume disease), decreased dose to critical organs(especially for small cervix), confirmation of applicator placement, and accounting for sigmoid colon dose. A number of modalities for image-based brachytherapy have emerged including: magnetic resonance imaging(MRI),computed tomography(CT), CT-MRI hybrid, and ultrasound with respective benefits and outcomes data. Forpractical application of image-based brachytherapy the Groupe Europeen de Curietherapie-European Society for Therapeutic Radiology and Oncology Working Group and American Brachytherapy Society working group guideline serve as invaluable tools, additionally here-in we outline our institutional clinical integration of these guidelines. While the body of literature supporting image-based brachytherapy continues to evolve a number of uncertainties and challenges remain including: applicator reconstruction, increasing resource/cost demands, mobile four-dimensional targets and organs-at-risk, and accurate contouring of "grey zones" to avoid marginal miss. Ongoing studies, including the prospective EMBRACE(an international study of MRI-guided brachytherapy in locally advanced cervical cancer) trial, along with continued improvements in imaging, contouring, quality assurance, physics, and brachytherapy delivery promise to perpetuate the advancement of image-based brachytherapy to optimize outcomes for cervical cancer patients.展开更多
An Introduction of Cultures and Societies of English-speaking Countries is a required university course for English majors to provide background knowledge in China.The traditional teaching mode,focusing on presenting ...An Introduction of Cultures and Societies of English-speaking Countries is a required university course for English majors to provide background knowledge in China.The traditional teaching mode,focusing on presenting cultural background knowledge by purely input information,has some limitations,especially for the class more than 60 students.If we combine the Task-based Teaching method with the Cooperative Learning method to teach this course,we can at fully attract students to actively join the classroom teaching,transferring it from inputting knowledge to fostering the students' competence on self-studying and practices.展开更多
基金Supported by the National Natural Science Foundation of China (90604034, 10371127)
文摘In this paper, we present an improved identity-based society oriented signature scheme with anonymous signers, which satisfies： （1） when members leave or join an organization, the public verification key and the signature verification procedure are unchanged; （2） a user participates in several organizations at the same time, her secret key is only related with her identity. However, no previous schemes have these two properties.
文摘Cervical cancer is the third most common cancer in women worldwide; definitive radiation therapy and concurrent chemotherapy is the accepted standard of care for patients with node positive or locally advanced tumors > 4 cm. Brachytherapy is an important part of definitive radiotherapy shown to improve overall survival. While results for two-dimensional X-ray based brachytherapy have been good in terms of local control especially for early stage disease, unexplained toxicities and treatment failures remain. Improvements in brachytherapy planning have more recently paved the way for three-dimensional image-based brachytherapy with volumetric optimization which increases tumor control, reduces toxicity, and helps predict outcomes.Advantages of image-based brachytherapy include:improved tumor coverage(especially for large volume disease), decreased dose to critical organs(especially for small cervix), confirmation of applicator placement, and accounting for sigmoid colon dose. A number of modalities for image-based brachytherapy have emerged including: magnetic resonance imaging(MRI),computed tomography(CT), CT-MRI hybrid, and ultrasound with respective benefits and outcomes data. Forpractical application of image-based brachytherapy the Groupe Europeen de Curietherapie-European Society for Therapeutic Radiology and Oncology Working Group and American Brachytherapy Society working group guideline serve as invaluable tools, additionally here-in we outline our institutional clinical integration of these guidelines. While the body of literature supporting image-based brachytherapy continues to evolve a number of uncertainties and challenges remain including: applicator reconstruction, increasing resource/cost demands, mobile four-dimensional targets and organs-at-risk, and accurate contouring of "grey zones" to avoid marginal miss. Ongoing studies, including the prospective EMBRACE(an international study of MRI-guided brachytherapy in locally advanced cervical cancer) trial, along with continued improvements in imaging, contouring, quality assurance, physics, and brachytherapy delivery promise to perpetuate the advancement of image-based brachytherapy to optimize outcomes for cervical cancer patients.
文摘An Introduction of Cultures and Societies of English-speaking Countries is a required university course for English majors to provide background knowledge in China.The traditional teaching mode,focusing on presenting cultural background knowledge by purely input information,has some limitations,especially for the class more than 60 students.If we combine the Task-based Teaching method with the Cooperative Learning method to teach this course,we can at fully attract students to actively join the classroom teaching,transferring it from inputting knowledge to fostering the students' competence on self-studying and practices.
