Occupational Therapy in Cancer Survivorship—A Toolkit for Stimulating Rapid-Research on the Neglected Domain of “Participation” during COVID-19

COVID-19 has disrupted people’s occupational daily activities with detrimental impact on their daily living performances and quality of life. Occupational therapy contributes toward restoring health by remediating limitation in participation in meaningful occupation with lifestyle redesign interventions. However, the research gap on the area of “participation-limitation” for the field of Occupational Therapy in cancer survivorship during the COVID-19 is largely untapped and unknown. This commentary-review paper discussed the PEO-OT (person-environment-occupation) grid as a conceptual toolkit for stimulating research in the domain of occupational participation—an essential aspect in the field of occupational therapy, for cancer survivors. It applies the expertise finding from a large Delphi study on research priority in the fields and integrating these into evidenced methodology, to provide a structure to guide the novice researchers towards rapid reviews, by selecting evidence-based methods to ensure contextually-relevant enquiry to identify the “occupational-participation issues”—i.e., an emerging social determinant of health, affecting the daily self-management of cancer survivors with or without comorbidities.

上海市艾滋病防治工作现状及对策建议

艾滋病是我国重点控制的传染病之一。我国政府高度重视艾滋病防治工作,制定发布了系列政策文件,全面加强艾滋病防治工作,以推进联合国2030年终结艾滋病流行可持续发展目标的实现。上海市按照国家相关要求,结合本市特点和工作实际,制定了上海市艾滋病防治工作目标,全面落实艾滋病防治责任与任务,持续推进各项防控措施,取得了明显成效。分析近年来上海市艾滋病防治工作进展及现状,并提出下一步工作对策及建议。

Responsible research and innovation training programmes:implementation and evaluation of the HEIRRI project

Responsible research and innovation,or RRI,is a concept that aims to bring together society and science for a better future.There are six key elements of RRI:public engagement,gender equality,science education,open access,ethics and governance.Higher Education Institutions and Responsible Research and Innovation(HEIRRI)project aimed to bring the concept of RRI into the educational system.Using state-of-the-art review of good practices,HEIRRI team developed 10 training programmes on RRI for different higher education institution educational levels,including a summer school and a massive open online course(MOOC).We conducted pilot of the trainings and evaluated participants’experiences.Satisfaction with HEIRRI training programmes on responsible research and innovation was high,both for participants and for the trainers,and trainings raised awareness of RRI.Participants’feedback was used to identify areas that need improvement and provided for recommendations for final versions of the HEIRRI training programmes.In order to equip researchers with skills to recognize and apply RRI values,RRI should be included in their education.HEIRRI training is suitable for a range of different disciplines,including forensic science,and is free to use and adjust for specific contexts(available from:https://rri-tools.eu/heirri-training-programmes).

Politicizing Responsible Innovation:Responsibility as Inclusive Governance

This paper aims to provide the historical and conceptual bases underlying the inclusionary transition of European innovation policy,and critical analysis of the difficulties relating to the political nature of this transition.In the 50s and 60s of last century,linear innovation models operated on the basis of a clear division of roles among the different actors in innovation and fundamentally economistic‐based strategies.The following decades saw innovation policies progressively recognize the multi‐dimensional and complex nature of innovation and the need to make adjustments,but always in explicit response to the competitiveness imperative.More recent RRI(Responsible Research and Innovation)strategy within the European Union,in contrast,demands opening up the whole innovation process(including values and motivations)to collective decision,i.e.,approaching responsible innovation as inclusive innovation.This paper appraises this important development primarily on the basis of in‐depth analysis of the main policy literature on innovation,and also on the grounds of related academic literature.As a result,we conclude that the bid for collaboration models cohabits constitutively with another set of dynamics aimed at strengthening centralized and prescriptive forms of innovation.In other words,that inclusionary or political eagerness represented through RRI must grapple with the strategic imperative of competitiveness and economic development.Hence,fundamental tension exists,which should be elucidated in light of the objectives,demands and considerations that are integrated,and cease to be integrated,in innovation dynamics and trajectories.

Responsible Research and Innovation and Its Implications for China

Responsible research and innovation （RRI） represents a new evotvtng approach to governing research and innovation that takes into account potential impacts on the environment and society. Most published studies on RRI focus on the social benefits of research and innovation through examining RRI＇s definitions and approaches for its implementation. In contrast, the present study addresses the influence of RRI on economic growth, and discusses the situations in which RRI will benefit economies. Our study finds that for its implementation to be successful RRI needs to meet certain conditions, and that its implementation is not always beneficial to economic growth. To achieve a better result from RRI as part of an innovation policy, each country should balance the push and pull power of RRI to make sure that it becomes a building block rather than a stumbling block for innovation, economic growth and social welfare. To assure that RRI can be successfully implemented, China needs to strengthen and improve the participation mechanisms for stakeholders in major scientific and technological innovative activities.

Exploring the social,ethical,legal,and responsibility dimensions of artificial intelligence for health-a new column in Intelligent Medicine

This essay is the starting point of a new column in Intelligent Medicine that invites interdisciplinary perspectives on the social,ethical,legal,and responsibility aspects of the use of artificial intelligence(AI)in medicine and health care.Papers in this column will examine the practical,conceptual,and policy dimensions of the use of AI for health-related purposes from comparative and international perspectives.We invite contributions from around the world in all application areas of AI for health,including health care,health research,drug development,health care system management,as well as public health and public health surveillance.The column aims to provide a forum for reflective and critical scholarship that contributes to the ongoing academic and policy debates about the development,use,governance,and implications of AI in medical and health care settings.To launch the column,we first provide an overview of recent approaches that have been developed to identify and address the effects and potential impacts of science and technology innovations on human societies and the environment.These include ethical,legal,and social implications/aspects(ELSI/A)research,responsible research and innovation(RRI),sustainability transitions research,and the use of international standard-setting instruments for responsible and open science issued by the United Nations Educational,Scientific,and Cultural Organization(UNESCO),the World Health Organization(WHO),and other international bodies.In Part Two of this essay,we discuss some of the central challenges that arise with regard to the integration of AI and big data analytics in medical and health care settings.This includes concerns regarding(i)the control,reliability,and trustworthiness of AI systems,(ii)privacy and surveillance,(iii)the impact of AI and automation on health care staffemployment and the nature of clinical work,(iv)the effects of AI on health inequalities,justice,and access to medical care,and(v)challenges related to regulation and governance.We end the essay with a call for papers and a set of questions that could be relevant for future studies.

RECENT RESEARCHES ON THE RESPONSES OF SHIPS AT SEAS IN CHINA

In China, the research works on the seakeeping of ships were started at the middle of 50's. At that time the ship models were generally tested in head or following waves in towing tanks. Afterwards, based on the theory of linear superpo- sition and stripping method, the simple ship motions were predicted theoretically. During the beginning of 70's, a 69×46×4m^3 seakeeping tank with a large movable bridge on it had been completed in the China Ship Scientific Research Center, Wuxi, then models could be tested in regular and irregular long crested. waves along any directions, thus realistic sea waves were simulated. In order to meet the demand of the oil-drilling beneath the sea bed, and to match the design works of drilling platforms, a large amount of research works on the wave forces acting on different kinds of poles were started. In this paper, the research works of recent ten years on the optimum seakeeping ship forms, roll and anti-rolling system, ship stability, waves and wave forces acting on ship and offshore structures are briefly reviewed. The references cited are limited to the papers published in the Shipbuilding of China, Advances in Hydrodynamics and some proceedings of international confer- ences.

Synthetic biology in the UK-An outline of plans and progress

Synthetic biology is capable of delivering new solutions to key challenges spanning the bioeconomy,both nationally and internationally.Recognising this significant potential and the associated need to facilitate its translation and commercialisation the UK government commissioned the production of a national Synthetic Biology Roadmap in 2011,and subsequently provided crucial support to assist its implementation.Critical infrastructural investments have been made,and important strides made towards the development of an effectively connected community of practitioners and interest groups.A number of Synthetic Biology Research Centres,DNA Synthesis Foundries,a Centre for Doctoral Training,and an Innovation Knowledge Centre have been established,creating a nationally distributed and integrated network of complementary facilities and expertise.The UK Synthetic Biology Leadership Council published a UK Synthetic Biology Strategic Plan in 2016,increasing focus on the processes of translation and commercialisation.Over 50 start-ups,SMEs and larger companies are actively engaged in synthetic biology in the UK,and inward investments are starting to flow.Together these initiatives provide an important foundation for stimulating innovation,actively contributing to international research and development partnerships,and helping deliver useful benefits from synthetic biology in response to local and global needs and challenges.

Synthetic biology techniques to tackle heavy metal pollution and poisoning

The requirement for natural resources and energy increases continually with the increase in population.An inevitable result of this is soil,water,and air pollution with diverse pollutants,including heavy metals.Synthetic Biology involves using modular,interchangeable biological parts,devices in standard chassis or whole organisms to achieve a programmed result that can be quantified and optimized till it meets the required efficiency.This makes synthetic biology techniques very popular to tackle pressing global issues such as heavy metal poisoning.This review aimed to highlight various advancements as well as benefits,risks,and problems in synthetic biology techniques for detection,bioaccumulation,and biosorption of various heavy metals using engineered organisms.We found that while such an approach is cost-effective,accessible,and efficient,there are several inherent technological and ethical issues including but not limited to metabolic burden and consequences of use of genetically modified organisms respectively.Overcoming these hurdles will probably take time and innumerable conversations,and should be done through education and a culture of responsible research,rather than enforcing restrictions on the development of synthetic biology.

Quick Responses of Canadian Social Scientists to COVID-19:A Case Study of the 2020 Federal COVID-19-Specific Grant Recipients

COVID-19 prompted an abundance of independent and collaborative quick response disaster research(QRDR)initiatives globally.The 2020 federal COVID-19-driven granting opportunities initiated the first official QRDR effort in Canadian history,engaging social scientists to rapidly address the pandemic-related societal influences.This study aims to portray the landscape of this nascent social science QRDR workforce through the first round of federal COVID-19-specific grant recipients.A case study approach was employed to analyze 337 social science projects with 1119 associated researchers,examining the demographic structure of these COVID-19-driven social science researchers and their research projects'characteristics.Accordingly,the findings are presented through the following two streams:(1)From a researcher perspective,this case study describes researcher typology,geographic location,primary discipline,and educational background,highlighting the diverse characteristics of social sciences researchers,and uneven research development across Canada.(2)From a research project perspective,this case study identifies and synthesizes research project subjects,themes,collaborations,and Canadian distinctions,emphasizing the need for galvanizing cooperation and focusing on uniquely Canadian contexts.The case study illustrates challenges associated with data curation that pose barriers to developing a nuanced understanding of the Canadian social science community COVID-19 research landscape.Consequently,the case study develops three recommendations to improve QRDR development in Canada:promoting information transparency,dissemination,and updates;improving hazards and disaster research workforce evaluation;and enhancing multi-stakeholder cooperation.