Battery energy storage stations(BESSs)pose sever-al challenges for both phasor-based differential protection and the newly-proposed time-domain differential protection.These challenges include low sensitivity and even...Battery energy storage stations(BESSs)pose sever-al challenges for both phasor-based differential protection and the newly-proposed time-domain differential protection.These challenges include low sensitivity and even rejection.Besides,the negative impact of various nonideal conditions,including current transformer(CT)saturation,errors,and outliers,on the security of differential protection remains an important problem.Motivated by the aforementioned issues,this study ac-counts for the trajectory distribution discrepancy on Cartesian plane under various conditions and proposes a time-domain dif-ferential protection method.In this paper,the trajectory formed by operating and restraining current samples is devel-oped.Subsequently,after considering different operating states,the fault severity levels,and nonideal conditions,the variances in trajectory distribution between internal and external faults are extensively analyzed.On this basis,the Cartesian plane is divided into operating,uncertainty,and restraining zones.Fur-ther,the operating and restraining trajectory indices are meticu-lously designed and a protection criterion based on these indi-ces is formed to accurately separate internal faults from other events,unaffected by CT saturation,errors,and outliers.The exceptional performance of the proposed protection method is extensively validated through PSCAD simulations and a hard-ware-in-the-loop testing platform.Regarding the dependability,sensitivity,and security,the proposed protection method outper-forms three state-of-the-art differential protection methods.展开更多
In sheet metal forming, drawbeads are often used to control uneven material flow which may cause defects such as wrinkles, fracture, surface distortion and springback. Appropriate setting and adjusting the drawbead ...In sheet metal forming, drawbeads are often used to control uneven material flow which may cause defects such as wrinkles, fracture, surface distortion and springback. Appropriate setting and adjusting the drawbead force is one of the most important pa- rameters in sheet metal forming process control. This paper derives the model of loop drawbead restraining force (DBRF) using plastic forming theory, and gives the min imum blankholding force. Experiments are carried out to verify the proposed DBRF model. The good agreement between the calculated values and experiments data justi- fies the proposed loop drawbead restraining force model.展开更多
Due to complexities of draw-bead restraining force calculated according to theory and depending on sheet metal forming properties experiment testing system, a simplified method to calculate draw-bead restraining force...Due to complexities of draw-bead restraining force calculated according to theory and depending on sheet metal forming properties experiment testing system, a simplified method to calculate draw-bead restraining force is put forward by experimental method in cup-shaped drawing process. The experimental results were compared with numerical results and proved agreement. It shows the method is effective.展开更多
The extracts from leaves of Manglietia insignis (Wall) Blume, Manglietia chingii Dandy and Manglietia yuyuanensis Law were prepared by organic solvent extraction and their components were analyzed by GC/MS and quant...The extracts from leaves of Manglietia insignis (Wall) Blume, Manglietia chingii Dandy and Manglietia yuyuanensis Law were prepared by organic solvent extraction and their components were analyzed by GC/MS and quantified. Meanwhile, the free radicals restraining activities were detected. The 21 compounds in M. insignis, 36 compounds in M. chigii and 20 compounds in M. yuyuanensis were identified. There were 11 common components in the extracts from three Manglietia species, and 12 components in two Manglietia species. The results of relative contents of every component in three extracts showed that the main constituents of M. insignis were terpenoids and alkene, amounting to 38.93%, followed by alkane (28.18%), the nitrogen containing compounds (15.73%) and aromatic compounds (7.23 %). The main constituents of leaf extract from M. chingii were the terpenoids and alkene, carboxylic acid, alkane and aromatic compounds, amounting to 30.22%, 14.17%, 13.87% and 13.29%, respectively, The main constituents of M. yuyuanensis were alcohol compounds, the terpenoids and alkene, and aromatic compounds, amounting to 28.00%, 25.38% and 18.00% respectively. The results showed that the three extracts had strong function of restraining oxygen free radicals. The ultra oxygen anions activity was restrained at the highest level, when the three extracts were diluted by hundred-fold, whereas the restraining capacity of hydroxyl free radicals reached maximum, when the three extracts were diluted by twenty-fold. The above results provide scientific evidences for further approaching the ecological healthy function of three MangUetia species展开更多
The method of planning acceleration is discussed to restrain the residual vibration of flexible arm. Based on the built mathematical model of the flexible arm, the equations of vibration with acceleration,vibration f...The method of planning acceleration is discussed to restrain the residual vibration of flexible arm. Based on the built mathematical model of the flexible arm, the equations of vibration with acceleration,vibration frequency,damping and time are obtained theoretically.According to the vibration frequency and damping, the suitable acceleration is executed experimentally to the flexible arm at the corresponding time. The result shows that this way can give rise to good effect to restrain the residual vibration.展开更多
The effects of various combustion conditions (i. e. particle size of coals, oxygen concentration in combustion gas and coal content in the fuel bed, etc.), on reducing conversion of NO_x during coal combustion were st...The effects of various combustion conditions (i. e. particle size of coals, oxygen concentration in combustion gas and coal content in the fuel bed, etc.), on reducing conversion of NO_x during coal combustion were studied. Under the present combustion conditions, coals with smaller particle size gave the lower conversion of NO_x, and as expected that an decrease in overall stoichiometric ratio, whether by an decrease in O_2 content in combustion gas or by an increase in coal content in fuel bed would lead to a lower conversion of NO_x. In order to investigate the effect of metallic oxide layers on restraining NO_x formation, the combustion experiments for coal granules with adhering layer of various metallic oxides including Fe_2O_3, Ni_2O_3 and mixed oxides Fe-Ni-O_x were conducted in a packed bed combustor. The combustion experiments have shown that most of adhering materials gave considerable effect on reduction of NO_x emission during coal combustion.展开更多
The expansive behaviors of the expensive concrete under different restraining conditions were systemically studied. The experimental results indicate that expansive deformation obviously increases before 10 days and t...The expansive behaviors of the expensive concrete under different restraining conditions were systemically studied. The experimental results indicate that expansive deformation obviously increases before 10 days and tends to be constant after 25 days regardless of the restraining conditions. The mixture ratio of expansive cement and restraining conditions are the main factors affecting expansive deformation. Self-stress can be obtained when the expansive deformation is restrained. The higher self-stress could be obtained when the expensive concrete is restrained by steel tube. For specimens under steel tube restraining, the wall thickness and the length of the steel tube have important influence on self-stress. Both the radial self-stress and axial self-stress in concrete core increase when wall thickness or length of the steel tube increases.展开更多
The new rural cooperative medical system has achieved periodical achievements since its establishment.Nevertheless,there are many factors hampering the development of the new system,such as the high cost,the difficult...The new rural cooperative medical system has achieved periodical achievements since its establishment.Nevertheless,there are many factors hampering the development of the new system,such as the high cost,the difficulties in fund procurement,the lack of management,the narrow coverage of benefit,the ineffective constraint to the designated medical institutions,the high fund balance rate,and the poor medical facilities and services in rural areas.Countermeasures are put forward to solve these problems,including improving the system design,expanding the coverage of the system,expanding the fund sources,reducing the financing costs,strengthening the fund supervision,enhancing the supervision of designated medical institutions,and improving the capacity of health services in rural areas.展开更多
The metabolic state of a cell is closely related to its structure and function in adult mammalian cardiomyocytes.These adult cardiomyocytes primarily use fatty acids as an energy substrate to support heart contraction...The metabolic state of a cell is closely related to its structure and function in adult mammalian cardiomyocytes.These adult cardiomyocytes primarily use fatty acids as an energy substrate to support heart contraction.Recently,Li and his colleagues reported that inhibiting fatty acid oxidation in cardiomyocytes keeps them in an immature state.This influences epigenomic modifications and ultimately increases the proliferation capacity of the cardiomyocytes.展开更多
1.Introduction Cities are responsible for approximately 70%of all anthropogenic greenhouse gas(GHG)emissions and about 60%of all anthropogenic methane(CH4)emissions[1,2].Solid waste disposal sites(including landfills ...1.Introduction Cities are responsible for approximately 70%of all anthropogenic greenhouse gas(GHG)emissions and about 60%of all anthropogenic methane(CH4)emissions[1,2].Solid waste disposal sites(including landfills and dumpsites),which are prevalent in global cities,emit CH4 generated from the anaerobic biodegradation of municipal solid waste(MSW).Notably,the proportions of CH4 emissions from disposal sites surpass 50%of the total CH4 emissions in some megalopolises[3].CH4 has a high global warming potential(GWP),being 28 times stronger than carbon dioxide(CO_(2))over a 100-year period and 80 times stronger over a 20-year period[4].Understanding and mitigating CH4 emissions from solid waste disposal sites is particularly pertinent and pressing,considering that the latest Synthesis Report from the Intergovernmental Panel on Climate Change(IPCC)emphasizes that the current pace of mitigation and adaptation policies and measures falls short of restraining global temperature rise to under 1.5℃ within the 21st century[4].More than 150 countries signed the Global Methane Pledge at the United Nations Climate Change Conference in Glasgow(COP26),which aims to reduce global annual CH4 emissions by 30%by 2030,compared with emissions in 2020[5].展开更多
The ultimate strength of platings under compression is one of the most important factors to be addressed in the ship design.Current Rules for ship structural design generally provide explicit strength check criteria a...The ultimate strength of platings under compression is one of the most important factors to be addressed in the ship design.Current Rules for ship structural design generally provide explicit strength check criteria against buckling for simply supported and clamped platings.Nevertheless,ship platings generally exhibit an intermediate behaviour between the simple support and the clamped conditions,which implies that the torsional stiffness of supporting members should be duly considered.Hence,the main aim of this study is the development of new design formulas for the ultimate strength of platings under uniaxial compression,with short and/or long edges elastically restrained against torsion.In this respect,two benchmark studies are performed.The former is devoted to the development of new equations for the elastic buckling coefficients of platings with edges elastically restrained against torsion,based on the results of the eigenvalue buckling analysis,performed by Ansys Mechanical APDL.The latter investigates the ultimate strength of platings with elastically restrained edges,by systematically varying the plate slenderness ratio and the torsional stiffness of supporting members.Finally,the effectiveness of the new formulation is checked against a wide number of finite element(FE)simulations,to cover the entire design space of ship platings.展开更多
Brain-Machine Interface System Unveiled at Zhongguancun Forum The NeuCyber Array BMI System,a self-developed brain-machine interface(BMI)system from China,was unveiled at the opening ceremony of the 2024 Zhongguancun ...Brain-Machine Interface System Unveiled at Zhongguancun Forum The NeuCyber Array BMI System,a self-developed brain-machine interface(BMI)system from China,was unveiled at the opening ceremony of the 2024 Zhongguancun Forum(ZGC Forum)on April 25 in Beijing.At the forum,a video demonstration revealed a remarkable feat:a monkey,with its hands restrained and soft electrode filaments implanted in its brain,grasped a strawberry with an isolated robotic arm that was controlled by simply using its"thoughts."展开更多
The study aims to understand geometry and evolution of accommodation zones along restraining and releasing bends in strike slip systems which is often complex and characterized by sharp change in polarity,resulting in...The study aims to understand geometry and evolution of accommodation zones along restraining and releasing bends in strike slip systems which is often complex and characterized by sharp change in polarity,resulting in a difficult characterization of traps location.A batch of sandbox modelling experiments was performed using a layered scaled sand material.The setup parameters of the wooden baseplates used in the first two experiments(SS1 and SS2)are basement offset of 6.5 cm/3 cm,90/90stepovers in releasing and restraining bends of total 96 cm length and 25 cm width.The third experiment(SS3)was performed with basement offset of 6.5 cm/3 cm,156/126stepovers in releasing and restraining bends of total 96 cm length and 25 cm width.The experiments were performed with special attention to the role of syn-kinematic sedimentation and the pre-existing structure of the basement.A sequence of pop-up and pull-apart structures was produced.Along the main structures,complex fault trend was compatible with a sinistral riedel distribution and a counterclockwise rotation of pre-existent elements.Change of fault's polarity at depth and dip direction flipping of high angle faults in accommodation zones were clearly observed.Even more,progressive propagation of the pop-up structures produces a spectacular inversion of adjacent extensional structures.Comparing results of the model with the Seagap fault zone,it is possible to put in evidence similar fault orientation and distribution.Internal structures developed were strongly influenced by syn-kinematic sedimentation as observed by characteristic helicoidal shape of growth faults.The analogue models clearly describe how boundary faults of the pull-apart basin along a paired bend,initially characterized by a normal kinematic can be subsequently inverted in the later stages,which can potentially have a strong impact on the petroleum system.展开更多
Notable differences in the structural characteristics and evolution of three adjacent sub-sags,i.e.,the Wenchang sub-sags A,B,and C,on the downthrown side of the Zhu IlI South Fault in the Wenchang Sag,are significant...Notable differences in the structural characteristics and evolution of three adjacent sub-sags,i.e.,the Wenchang sub-sags A,B,and C,on the downthrown side of the Zhu IlI South Fault in the Wenchang Sag,are significant as they affect the formation and distribution of the oil and gas in these three sub-sags.However,the differences in their tectonic evolutions and formation mechanisms have not yet been adequately explained.In this paper,stress analysis,equilibrium profiles,and paleogeomorphic restora-tion,are used to investigate the dynamic settings,formation mechanisms,and influencing factors of the structural deformation related to the formation of the Wenchang Sag based on interpretation of seismic data.The results of the stress analysis suggest clockwise deflection of the regional tensile stress direction from a WNW-ESE trend during the Early Paleocene to NW-SE and NNW-SSE trends during the Eocene,to a nearly N-S trend during the Oligocene,and finally to a NNE-SSW trend during the Miocene.This clockwise rotation of the regional tensile stress direction led to the formation of a dextral strike-slip stress component parallel to the NE-trending Zhu I South Fault.This strike-slip stress component formed a releasing bend in sub-sag A,and may be associated with the continuous subsidence of a thick sedimentary layer in sub-sag A.It also created a restraining bend in sub-sag B,which underwent multiple structural inversions during its extension and subsidence and has a relatively s mall sedimentary thick-ness.The double restraining bend in sub-sag C is considered to have been strongly uplifted and eroded in response to this strike-slip stress component.Four obvious structural inversions in sub-sag B are iden-tified in this paper.These structural inversions correspond to the last four regional tectonic movements.This interpretation suggests that the formation of the structural inversions was likely related to the strong tensile stress and the small intersection angle between the direction of the regional tensile stress and the pre-existing boundary fault.The rotation of the tensile stress direction was responsible for the strike-slip movement on the pre-existing boundary fault and the formation of the releasing bend and restraining bend,which controlled the structural evolutions of the sub-sags.This reasonably explains the differential tectonic evolution of these three sub-sags in the Wenchang Sag,and provides a crucial idea forstructuralanalysisof similarbasins.展开更多
This paper presents a simplified elastic continuum method for calculating the restraint effect of isolation piles on tunneling-induced vertical ground displacement,which can consider not only the relative sliding of t...This paper presents a simplified elastic continuum method for calculating the restraint effect of isolation piles on tunneling-induced vertical ground displacement,which can consider not only the relative sliding of the pile‒soil interface but also the pile rowesoil interaction.The proposed method is verified by comparisons with existing theoretical methods,including the boundary element method and the elastic foundation method.The results reveal the restraining mechanism of the isolation piles on vertical ground displacements due to tunneling,i.e.the positive and negative restraint effects exerted by the isolation piles jointly drive the ground vertical displacement along the depth direction from the original tunneling-induced nonlinear variation situation to a relatively uniform situation.The results also indicate that the stiffness of the pile‒soil interface,including the pile shaft‒surrounding soil interface and pile tip-supporting soil interface,describes the strength of the pile‒soil interaction.The pile rows can confine the vertical ground displacement caused by the tunnel excavation to the inner side of the isolation piles and effectively prevent the vertical ground displacement from expanding further toward the outer side of the isolation piles.展开更多
Metabolic rewiring underlies the effector functions of macrophages1-3,but the mechanisms involved remain incompletely defined.Here,using unbiased metabolomics and stable isotope-assisted tracing,we show that an inflam...Metabolic rewiring underlies the effector functions of macrophages1-3,but the mechanisms involved remain incompletely defined.Here,using unbiased metabolomics and stable isotope-assisted tracing,we show that an inflammatory aspartate argininosuccinate shunt is induced following lipopolysaccharide stimulation.The shunt,supported by increased argininosuccinate synthase(ASS1)expression,also leads to increased cytosolic fumarate levels and fumarate-mediated protein succination.Pharmacological inhibition and genetic ablation of the tricarboxylic acid cycle enzyme fumarate hydratase(FH)further increases intracellular fumarate levels.展开更多
Based on the background of structural protection and Disaster Reduction Engineering, the dynamic behaviour and failure mechanism of restrained beams in portal steel frames in localised fire are investigated via experi...Based on the background of structural protection and Disaster Reduction Engineering, the dynamic behaviour and failure mechanism of restrained beams in portal steel frames in localised fire are investigated via experimental measurement and numerical simulation techniques. Comprehensive parametric studies are carried out to discuss the influence of end connection types, temperature, impact velocity,impact mass and span-to-depth ratio(SDR) on the dynamic response of the beams. The characteristics of deformation, internal force and energy distribution about the restrained beams and its joints are investigated. A temperature dependent criterion for evaluating the frame joint performance is proposed to measure the degree of performance degradation and impact resistance of the joint. The dynamic displacement amplification factor in different temperature environments are proposed for the different beam end constraint types and SDRs. Results of the experimental and numerical analysis show that the welded connection(WC) of three typical joint types is the strongest, and the extended endplate connection(EEC) is the weakest in terms of the impact resistance performance. With regard to the failure mode of the joint, the failure positions of the WC and the welded-bolted connection are located in the inner web of the column. Meanwhile, the EEC is located in the connection position between the beam and the endplate. Three different internal force stages and two obvious critical temperature boundaries of the restrained beams emerge with the increase in temperature, and they have significant characteristics in terms of deformation trend, internal force transfer and energy distribution. During the impact, a phenomenon known as “compression arch action” develops into “catenary action” with the increase in deflection in the frame beam mechanism.展开更多
Dear Editor, This letter considers the control problem of an experimental flexible manipulator in position tracking, vibration suppression, and saturation compensation. Based on the backstepping technology and a Nussb...Dear Editor, This letter considers the control problem of an experimental flexible manipulator in position tracking, vibration suppression, and saturation compensation. Based on the backstepping technology and a Nussbaum function, we develop an anti-windup control to restrain the manipulator’s vibration, realize the desire trajectory tracking, and eliminate the saturation.展开更多
As the saying goes,in the prime of life,teenagers should be more energetic and unrestrained.At various CDMUN(中报模拟联合国)conferences,she seized every opportunity which can improve herself and composed(组成)her yout...As the saying goes,in the prime of life,teenagers should be more energetic and unrestrained.At various CDMUN(中报模拟联合国)conferences,she seized every opportunity which can improve herself and composed(组成)her youth with actions.展开更多
基金supported in part by the National Natural Science Foundation of China(No.52277i32)in part by the Fundamental Research Funds for the Central Universities(No.2024JCCXJD01).
文摘Battery energy storage stations(BESSs)pose sever-al challenges for both phasor-based differential protection and the newly-proposed time-domain differential protection.These challenges include low sensitivity and even rejection.Besides,the negative impact of various nonideal conditions,including current transformer(CT)saturation,errors,and outliers,on the security of differential protection remains an important problem.Motivated by the aforementioned issues,this study ac-counts for the trajectory distribution discrepancy on Cartesian plane under various conditions and proposes a time-domain dif-ferential protection method.In this paper,the trajectory formed by operating and restraining current samples is devel-oped.Subsequently,after considering different operating states,the fault severity levels,and nonideal conditions,the variances in trajectory distribution between internal and external faults are extensively analyzed.On this basis,the Cartesian plane is divided into operating,uncertainty,and restraining zones.Fur-ther,the operating and restraining trajectory indices are meticu-lously designed and a protection criterion based on these indi-ces is formed to accurately separate internal faults from other events,unaffected by CT saturation,errors,and outliers.The exceptional performance of the proposed protection method is extensively validated through PSCAD simulations and a hard-ware-in-the-loop testing platform.Regarding the dependability,sensitivity,and security,the proposed protection method outper-forms three state-of-the-art differential protection methods.
文摘In sheet metal forming, drawbeads are often used to control uneven material flow which may cause defects such as wrinkles, fracture, surface distortion and springback. Appropriate setting and adjusting the drawbead force is one of the most important pa- rameters in sheet metal forming process control. This paper derives the model of loop drawbead restraining force (DBRF) using plastic forming theory, and gives the min imum blankholding force. Experiments are carried out to verify the proposed DBRF model. The good agreement between the calculated values and experiments data justi- fies the proposed loop drawbead restraining force model.
基金Supported by Science and Technology Development Foundation of Shanghai (015211009).
文摘Due to complexities of draw-bead restraining force calculated according to theory and depending on sheet metal forming properties experiment testing system, a simplified method to calculate draw-bead restraining force is put forward by experimental method in cup-shaped drawing process. The experimental results were compared with numerical results and proved agreement. It shows the method is effective.
基金This paper was supported by the National "Eleven .Five" Scientific and Technological Supporting project "Test and demonstration for typical region city forest construction technol-ogy(2006BAD03A19) "
文摘The extracts from leaves of Manglietia insignis (Wall) Blume, Manglietia chingii Dandy and Manglietia yuyuanensis Law were prepared by organic solvent extraction and their components were analyzed by GC/MS and quantified. Meanwhile, the free radicals restraining activities were detected. The 21 compounds in M. insignis, 36 compounds in M. chigii and 20 compounds in M. yuyuanensis were identified. There were 11 common components in the extracts from three Manglietia species, and 12 components in two Manglietia species. The results of relative contents of every component in three extracts showed that the main constituents of M. insignis were terpenoids and alkene, amounting to 38.93%, followed by alkane (28.18%), the nitrogen containing compounds (15.73%) and aromatic compounds (7.23 %). The main constituents of leaf extract from M. chingii were the terpenoids and alkene, carboxylic acid, alkane and aromatic compounds, amounting to 30.22%, 14.17%, 13.87% and 13.29%, respectively, The main constituents of M. yuyuanensis were alcohol compounds, the terpenoids and alkene, and aromatic compounds, amounting to 28.00%, 25.38% and 18.00% respectively. The results showed that the three extracts had strong function of restraining oxygen free radicals. The ultra oxygen anions activity was restrained at the highest level, when the three extracts were diluted by hundred-fold, whereas the restraining capacity of hydroxyl free radicals reached maximum, when the three extracts were diluted by twenty-fold. The above results provide scientific evidences for further approaching the ecological healthy function of three MangUetia species
文摘The method of planning acceleration is discussed to restrain the residual vibration of flexible arm. Based on the built mathematical model of the flexible arm, the equations of vibration with acceleration,vibration frequency,damping and time are obtained theoretically.According to the vibration frequency and damping, the suitable acceleration is executed experimentally to the flexible arm at the corresponding time. The result shows that this way can give rise to good effect to restrain the residual vibration.
文摘The effects of various combustion conditions (i. e. particle size of coals, oxygen concentration in combustion gas and coal content in the fuel bed, etc.), on reducing conversion of NO_x during coal combustion were studied. Under the present combustion conditions, coals with smaller particle size gave the lower conversion of NO_x, and as expected that an decrease in overall stoichiometric ratio, whether by an decrease in O_2 content in combustion gas or by an increase in coal content in fuel bed would lead to a lower conversion of NO_x. In order to investigate the effect of metallic oxide layers on restraining NO_x formation, the combustion experiments for coal granules with adhering layer of various metallic oxides including Fe_2O_3, Ni_2O_3 and mixed oxides Fe-Ni-O_x were conducted in a packed bed combustor. The combustion experiments have shown that most of adhering materials gave considerable effect on reduction of NO_x emission during coal combustion.
基金Funded by the NSFC (No.50578027)the Key Subject Foundation of Henan Province (No.504906)the Doctor Foundation of Henan Polytechnic University (No.B2009-2)
文摘The expansive behaviors of the expensive concrete under different restraining conditions were systemically studied. The experimental results indicate that expansive deformation obviously increases before 10 days and tends to be constant after 25 days regardless of the restraining conditions. The mixture ratio of expansive cement and restraining conditions are the main factors affecting expansive deformation. Self-stress can be obtained when the expansive deformation is restrained. The higher self-stress could be obtained when the expensive concrete is restrained by steel tube. For specimens under steel tube restraining, the wall thickness and the length of the steel tube have important influence on self-stress. Both the radial self-stress and axial self-stress in concrete core increase when wall thickness or length of the steel tube increases.
基金Supported by the School Management Project of Xi an Polytechnic University(09XG38)
文摘The new rural cooperative medical system has achieved periodical achievements since its establishment.Nevertheless,there are many factors hampering the development of the new system,such as the high cost,the difficulties in fund procurement,the lack of management,the narrow coverage of benefit,the ineffective constraint to the designated medical institutions,the high fund balance rate,and the poor medical facilities and services in rural areas.Countermeasures are put forward to solve these problems,including improving the system design,expanding the coverage of the system,expanding the fund sources,reducing the financing costs,strengthening the fund supervision,enhancing the supervision of designated medical institutions,and improving the capacity of health services in rural areas.
文摘The metabolic state of a cell is closely related to its structure and function in adult mammalian cardiomyocytes.These adult cardiomyocytes primarily use fatty acids as an energy substrate to support heart contraction.Recently,Li and his colleagues reported that inhibiting fatty acid oxidation in cardiomyocytes keeps them in an immature state.This influences epigenomic modifications and ultimately increases the proliferation capacity of the cardiomyocytes.
基金Nanyang Technological University(NTU),Singapore,for providing research scholarships for this study.The authors thank the supports from Debris of the Anthropocene to Resources(DotA2)Lab at NTU.
文摘1.Introduction Cities are responsible for approximately 70%of all anthropogenic greenhouse gas(GHG)emissions and about 60%of all anthropogenic methane(CH4)emissions[1,2].Solid waste disposal sites(including landfills and dumpsites),which are prevalent in global cities,emit CH4 generated from the anaerobic biodegradation of municipal solid waste(MSW).Notably,the proportions of CH4 emissions from disposal sites surpass 50%of the total CH4 emissions in some megalopolises[3].CH4 has a high global warming potential(GWP),being 28 times stronger than carbon dioxide(CO_(2))over a 100-year period and 80 times stronger over a 20-year period[4].Understanding and mitigating CH4 emissions from solid waste disposal sites is particularly pertinent and pressing,considering that the latest Synthesis Report from the Intergovernmental Panel on Climate Change(IPCC)emphasizes that the current pace of mitigation and adaptation policies and measures falls short of restraining global temperature rise to under 1.5℃ within the 21st century[4].More than 150 countries signed the Global Methane Pledge at the United Nations Climate Change Conference in Glasgow(COP26),which aims to reduce global annual CH4 emissions by 30%by 2030,compared with emissions in 2020[5].
文摘The ultimate strength of platings under compression is one of the most important factors to be addressed in the ship design.Current Rules for ship structural design generally provide explicit strength check criteria against buckling for simply supported and clamped platings.Nevertheless,ship platings generally exhibit an intermediate behaviour between the simple support and the clamped conditions,which implies that the torsional stiffness of supporting members should be duly considered.Hence,the main aim of this study is the development of new design formulas for the ultimate strength of platings under uniaxial compression,with short and/or long edges elastically restrained against torsion.In this respect,two benchmark studies are performed.The former is devoted to the development of new equations for the elastic buckling coefficients of platings with edges elastically restrained against torsion,based on the results of the eigenvalue buckling analysis,performed by Ansys Mechanical APDL.The latter investigates the ultimate strength of platings with elastically restrained edges,by systematically varying the plate slenderness ratio and the torsional stiffness of supporting members.Finally,the effectiveness of the new formulation is checked against a wide number of finite element(FE)simulations,to cover the entire design space of ship platings.
文摘Brain-Machine Interface System Unveiled at Zhongguancun Forum The NeuCyber Array BMI System,a self-developed brain-machine interface(BMI)system from China,was unveiled at the opening ceremony of the 2024 Zhongguancun Forum(ZGC Forum)on April 25 in Beijing.At the forum,a video demonstration revealed a remarkable feat:a monkey,with its hands restrained and soft electrode filaments implanted in its brain,grasped a strawberry with an isolated robotic arm that was controlled by simply using its"thoughts."
基金This research paper was prepared from the experimental data simulated with Sandbox analogy modelling machine in the Geomodel laboratory of College of Earth sciences,University of Dodoma.Our appreciation goes to senior LabEngineer Mr Audax Kiwango for his tireless technical support in operating the Sandbox machine and Statoil Tanzania(Equinor)for providing information of structural architecture of their play。
文摘The study aims to understand geometry and evolution of accommodation zones along restraining and releasing bends in strike slip systems which is often complex and characterized by sharp change in polarity,resulting in a difficult characterization of traps location.A batch of sandbox modelling experiments was performed using a layered scaled sand material.The setup parameters of the wooden baseplates used in the first two experiments(SS1 and SS2)are basement offset of 6.5 cm/3 cm,90/90stepovers in releasing and restraining bends of total 96 cm length and 25 cm width.The third experiment(SS3)was performed with basement offset of 6.5 cm/3 cm,156/126stepovers in releasing and restraining bends of total 96 cm length and 25 cm width.The experiments were performed with special attention to the role of syn-kinematic sedimentation and the pre-existing structure of the basement.A sequence of pop-up and pull-apart structures was produced.Along the main structures,complex fault trend was compatible with a sinistral riedel distribution and a counterclockwise rotation of pre-existent elements.Change of fault's polarity at depth and dip direction flipping of high angle faults in accommodation zones were clearly observed.Even more,progressive propagation of the pop-up structures produces a spectacular inversion of adjacent extensional structures.Comparing results of the model with the Seagap fault zone,it is possible to put in evidence similar fault orientation and distribution.Internal structures developed were strongly influenced by syn-kinematic sedimentation as observed by characteristic helicoidal shape of growth faults.The analogue models clearly describe how boundary faults of the pull-apart basin along a paired bend,initially characterized by a normal kinematic can be subsequently inverted in the later stages,which can potentially have a strong impact on the petroleum system.
基金supported by the National Natural Science Foundation of China(Grant No.9132820142006068)Shandong Special Fund of Qingdao National Laboratory of Marine Science and Technology(No.2021QNLM020001-1).
文摘Notable differences in the structural characteristics and evolution of three adjacent sub-sags,i.e.,the Wenchang sub-sags A,B,and C,on the downthrown side of the Zhu IlI South Fault in the Wenchang Sag,are significant as they affect the formation and distribution of the oil and gas in these three sub-sags.However,the differences in their tectonic evolutions and formation mechanisms have not yet been adequately explained.In this paper,stress analysis,equilibrium profiles,and paleogeomorphic restora-tion,are used to investigate the dynamic settings,formation mechanisms,and influencing factors of the structural deformation related to the formation of the Wenchang Sag based on interpretation of seismic data.The results of the stress analysis suggest clockwise deflection of the regional tensile stress direction from a WNW-ESE trend during the Early Paleocene to NW-SE and NNW-SSE trends during the Eocene,to a nearly N-S trend during the Oligocene,and finally to a NNE-SSW trend during the Miocene.This clockwise rotation of the regional tensile stress direction led to the formation of a dextral strike-slip stress component parallel to the NE-trending Zhu I South Fault.This strike-slip stress component formed a releasing bend in sub-sag A,and may be associated with the continuous subsidence of a thick sedimentary layer in sub-sag A.It also created a restraining bend in sub-sag B,which underwent multiple structural inversions during its extension and subsidence and has a relatively s mall sedimentary thick-ness.The double restraining bend in sub-sag C is considered to have been strongly uplifted and eroded in response to this strike-slip stress component.Four obvious structural inversions in sub-sag B are iden-tified in this paper.These structural inversions correspond to the last four regional tectonic movements.This interpretation suggests that the formation of the structural inversions was likely related to the strong tensile stress and the small intersection angle between the direction of the regional tensile stress and the pre-existing boundary fault.The rotation of the tensile stress direction was responsible for the strike-slip movement on the pre-existing boundary fault and the formation of the releasing bend and restraining bend,which controlled the structural evolutions of the sub-sags.This reasonably explains the differential tectonic evolution of these three sub-sags in the Wenchang Sag,and provides a crucial idea forstructuralanalysisof similarbasins.
基金support by the National Natural Science Foundation of China(Grant Nos.52108376 and 51908371)China Postdoctoral Science Foundation(Grant No.2022T150436).
文摘This paper presents a simplified elastic continuum method for calculating the restraint effect of isolation piles on tunneling-induced vertical ground displacement,which can consider not only the relative sliding of the pile‒soil interface but also the pile rowesoil interaction.The proposed method is verified by comparisons with existing theoretical methods,including the boundary element method and the elastic foundation method.The results reveal the restraining mechanism of the isolation piles on vertical ground displacements due to tunneling,i.e.the positive and negative restraint effects exerted by the isolation piles jointly drive the ground vertical displacement along the depth direction from the original tunneling-induced nonlinear variation situation to a relatively uniform situation.The results also indicate that the stiffness of the pile‒soil interface,including the pile shaft‒surrounding soil interface and pile tip-supporting soil interface,describes the strength of the pile‒soil interaction.The pile rows can confine the vertical ground displacement caused by the tunnel excavation to the inner side of the isolation piles and effectively prevent the vertical ground displacement from expanding further toward the outer side of the isolation piles.
文摘Metabolic rewiring underlies the effector functions of macrophages1-3,but the mechanisms involved remain incompletely defined.Here,using unbiased metabolomics and stable isotope-assisted tracing,we show that an inflammatory aspartate argininosuccinate shunt is induced following lipopolysaccharide stimulation.The shunt,supported by increased argininosuccinate synthase(ASS1)expression,also leads to increased cytosolic fumarate levels and fumarate-mediated protein succination.Pharmacological inhibition and genetic ablation of the tricarboxylic acid cycle enzyme fumarate hydratase(FH)further increases intracellular fumarate levels.
基金supported by the National natural Science Foundation of China [grant numbers 12172198, 11272189 and 52078283]Youth Innovation Technology Project of Higher School in Shandong Province [grant number 2019KJG015]。
文摘Based on the background of structural protection and Disaster Reduction Engineering, the dynamic behaviour and failure mechanism of restrained beams in portal steel frames in localised fire are investigated via experimental measurement and numerical simulation techniques. Comprehensive parametric studies are carried out to discuss the influence of end connection types, temperature, impact velocity,impact mass and span-to-depth ratio(SDR) on the dynamic response of the beams. The characteristics of deformation, internal force and energy distribution about the restrained beams and its joints are investigated. A temperature dependent criterion for evaluating the frame joint performance is proposed to measure the degree of performance degradation and impact resistance of the joint. The dynamic displacement amplification factor in different temperature environments are proposed for the different beam end constraint types and SDRs. Results of the experimental and numerical analysis show that the welded connection(WC) of three typical joint types is the strongest, and the extended endplate connection(EEC) is the weakest in terms of the impact resistance performance. With regard to the failure mode of the joint, the failure positions of the WC and the welded-bolted connection are located in the inner web of the column. Meanwhile, the EEC is located in the connection position between the beam and the endplate. Three different internal force stages and two obvious critical temperature boundaries of the restrained beams emerge with the increase in temperature, and they have significant characteristics in terms of deformation trend, internal force transfer and energy distribution. During the impact, a phenomenon known as “compression arch action” develops into “catenary action” with the increase in deflection in the frame beam mechanism.
基金supported in part by the National Natural Science Foundation of China(62273112)the Scientific Research Projects of Guangzhou Education Bureau(202032793)+1 种基金the Guangzhou University-Hong Kong University of Science and Technology Joint Research Collaboration Fund(YH202205)the Open Research Fund from the Guangdong Laboratory of Artificial Intelligence and Digital Economy[Shenzhen(SZ)](GML-KF-22-27)。
文摘Dear Editor, This letter considers the control problem of an experimental flexible manipulator in position tracking, vibration suppression, and saturation compensation. Based on the backstepping technology and a Nussbaum function, we develop an anti-windup control to restrain the manipulator’s vibration, realize the desire trajectory tracking, and eliminate the saturation.
文摘As the saying goes,in the prime of life,teenagers should be more energetic and unrestrained.At various CDMUN(中报模拟联合国)conferences,she seized every opportunity which can improve herself and composed(组成)her youth with actions.