The literature is full of claims regarding the consumption of polyphenol or polyamine-rich foods that offer some protection from developing cardiovascular disease(CVD). This is achieved by preventing cardiac hypertrop...The literature is full of claims regarding the consumption of polyphenol or polyamine-rich foods that offer some protection from developing cardiovascular disease(CVD). This is achieved by preventing cardiac hypertrophy and protecting blood vessels through improving the function of endothelium. However, do these interventions work in the aged human hearts? Cardiac aging is accompanied by an increase in left ventricular hypertrophy, along with diastolic and systolic dysfunction. It also confers significant cardiovascular risks for both sexes. The incidence and prevalence of CVD increase sharply at an earlier age in men than women. Furthermore, the patterns of heart failure differ between sexes, as do the lifetime risk factors. Do caloric restriction(CR)-mimetics, rich in polyphenol or polyamine, delay or reverse cardiac aging equally in both men and women? This review will discuss three areas:(1) mechanisms underlying age-related cardiac remodeling;(2) gender-related differences and potential mechanisms underlying diminished cardiac response in older men and women;(3) we select a few polyphenol or polyamine rich compounds as the CRmimetics, such as resveratrol, quercetin, curcumin, epigallocatechin gallate and spermidine, due to their capability to extend health-span and induce autophagy. We outline their abilities and issues on retarding aging in animal hearts and preventing CVD in humans. We discuss the confounding factors that should be considered for developing therapeutic strategies against cardiac aging in humans.展开更多
The problem of solving the linear diffusion equation by a method related to the Restrictive Pade Approximation (RPA) is considered. The advantage is that it has the exact value at certain r. This method will exhibit s...The problem of solving the linear diffusion equation by a method related to the Restrictive Pade Approximation (RPA) is considered. The advantage is that it has the exact value at certain r. This method will exhibit several advantages for example highly accurate, fast and with good results, etc. The absolutely error is still very small. The obtained results are compared with the exact solution and the other methods. The numerical results are in agreement with the exact solution.展开更多
The thermal buoyancy generated by the difference in air density in a building can drive hot-pressed natural ventilation,which is an energy-efficient means of ventilation used to obtain higher air quality.Therefore,the...The thermal buoyancy generated by the difference in air density in a building can drive hot-pressed natural ventilation,which is an energy-efficient means of ventilation used to obtain higher air quality.Therefore,the effect of a single-point heat source with limited sides at different heights on stratified flow was studied in a naturally ventilated room in this paper.Based on the classical plume diffusion law of an independent point heat source and the mirroring principle,a calculation model of the thermal stratification height with a restricted source elevated to different levels was derived and validated.The quantitative effects of the heat source height from the floor,the effective opening area and other factors on the natural ventilation of hot pressure were analyzed.A threshold X_(T)for the separation between a point source and a sidewall was defined to estimate whether the thermal plume was independent or restricted by a sidewall.And a method for calculating the threshold xt was obtained.This research can provide a reference basis for designing natural ventilation for buildings with a restricted heat source at different levels to achieve a desired indoor environment.展开更多
A restricted signed r-set is a pair （A, f）, where A lohtain in [n] = {1, 2,…, n} is an r-set and f is a map from A to [n] with f（i） ≠ i for all i ∈ A. For two restricted signed sets （A, f） and （B, g）, we d...A restricted signed r-set is a pair （A, f）, where A lohtain in [n] = {1, 2,…, n} is an r-set and f is a map from A to [n] with f（i） ≠ i for all i ∈ A. For two restricted signed sets （A, f） and （B, g）, we define an order as （A, f） ≤ （B, g） if A C B and g｜A ： f A family .A of restricted signed sets on [n] is an intersecting antiehain if for any （A, f）, （B, g） ∈ A, they are incomparable and there exists x ∈ A ∩ B such that f（x） = g（x）. In this paper, we first give a LYM-type inequality for any intersecting antichain A of restricted signed sets, from which we then obtain ｜A｜≤ （r-1^n-1）（n-1）^r-1 if A. consists of restricted signed r-sets on [n]. Unless r = n = 3, equality holds if and only if A consists of all restricted signed r-sets （A, f） such that x0∈ A and f（x0） =ε0 for some fixed x0 ∈ [n], ε0 ∈ [n] ／ {x0}.展开更多
受光强变化大、照度低以及车灯光晕等影响,夜间环境下车辆视频检测相对白天比较困难;文中采用帧差法求感兴趣区域(Region of Interesting,ROI),抑制夜间车灯光晕;并引入"疑是车辆"的概念。以消除车辆断层和随机噪声造成的车...受光强变化大、照度低以及车灯光晕等影响,夜间环境下车辆视频检测相对白天比较困难;文中采用帧差法求感兴趣区域(Region of Interesting,ROI),抑制夜间车灯光晕;并引入"疑是车辆"的概念。以消除车辆断层和随机噪声造成的车辆误检;同时,根据运动目标在车道内分布的离散度判断车型;对不同夜间交通场景进行测试,检测率均在96%以上;在广深高速公路实地应用中取得了很好效果。展开更多
基金supported by grants from the National Natural Science Foundation of China(81800245,81970228,82102306,81900779)the China Postdoctoral Science Foundation(2020M670030ZX)+1 种基金the Shaoguan Science and Technology Program(2019sn078)the Start-up Fund for RAPs under the Strategic Hiring Scheme(P0035913)。
文摘The literature is full of claims regarding the consumption of polyphenol or polyamine-rich foods that offer some protection from developing cardiovascular disease(CVD). This is achieved by preventing cardiac hypertrophy and protecting blood vessels through improving the function of endothelium. However, do these interventions work in the aged human hearts? Cardiac aging is accompanied by an increase in left ventricular hypertrophy, along with diastolic and systolic dysfunction. It also confers significant cardiovascular risks for both sexes. The incidence and prevalence of CVD increase sharply at an earlier age in men than women. Furthermore, the patterns of heart failure differ between sexes, as do the lifetime risk factors. Do caloric restriction(CR)-mimetics, rich in polyphenol or polyamine, delay or reverse cardiac aging equally in both men and women? This review will discuss three areas:(1) mechanisms underlying age-related cardiac remodeling;(2) gender-related differences and potential mechanisms underlying diminished cardiac response in older men and women;(3) we select a few polyphenol or polyamine rich compounds as the CRmimetics, such as resveratrol, quercetin, curcumin, epigallocatechin gallate and spermidine, due to their capability to extend health-span and induce autophagy. We outline their abilities and issues on retarding aging in animal hearts and preventing CVD in humans. We discuss the confounding factors that should be considered for developing therapeutic strategies against cardiac aging in humans.
文摘The problem of solving the linear diffusion equation by a method related to the Restrictive Pade Approximation (RPA) is considered. The advantage is that it has the exact value at certain r. This method will exhibit several advantages for example highly accurate, fast and with good results, etc. The absolutely error is still very small. The obtained results are compared with the exact solution and the other methods. The numerical results are in agreement with the exact solution.
基金supported by the Natural Science Foundation of Shaanxi Province(No.2020JQ-670)China Postdoctoral Science Foundation(No.2020M673353).
文摘The thermal buoyancy generated by the difference in air density in a building can drive hot-pressed natural ventilation,which is an energy-efficient means of ventilation used to obtain higher air quality.Therefore,the effect of a single-point heat source with limited sides at different heights on stratified flow was studied in a naturally ventilated room in this paper.Based on the classical plume diffusion law of an independent point heat source and the mirroring principle,a calculation model of the thermal stratification height with a restricted source elevated to different levels was derived and validated.The quantitative effects of the heat source height from the floor,the effective opening area and other factors on the natural ventilation of hot pressure were analyzed.A threshold X_(T)for the separation between a point source and a sidewall was defined to estimate whether the thermal plume was independent or restricted by a sidewall.And a method for calculating the threshold xt was obtained.This research can provide a reference basis for designing natural ventilation for buildings with a restricted heat source at different levels to achieve a desired indoor environment.
基金Supported by the doctoral Foundation of Yanshan University(No.B314)
文摘A restricted signed r-set is a pair （A, f）, where A lohtain in [n] = {1, 2,…, n} is an r-set and f is a map from A to [n] with f（i） ≠ i for all i ∈ A. For two restricted signed sets （A, f） and （B, g）, we define an order as （A, f） ≤ （B, g） if A C B and g｜A ： f A family .A of restricted signed sets on [n] is an intersecting antiehain if for any （A, f）, （B, g） ∈ A, they are incomparable and there exists x ∈ A ∩ B such that f（x） = g（x）. In this paper, we first give a LYM-type inequality for any intersecting antichain A of restricted signed sets, from which we then obtain ｜A｜≤ （r-1^n-1）（n-1）^r-1 if A. consists of restricted signed r-sets on [n]. Unless r = n = 3, equality holds if and only if A consists of all restricted signed r-sets （A, f） such that x0∈ A and f（x0） =ε0 for some fixed x0 ∈ [n], ε0 ∈ [n] ／ {x0}.
文摘货位分配(storage location assignment problem,SLAP),即在存储区域为物料分配货位的过程。当仓库布局、拣货路径、订单组合等其他因素确定时,货位分配策略对订单拣货效率有很大影响。本文研究实际生产型仓库中的关联物料区位分配问题。生产中使用的相对稳定的BOM(bill of material)使得仓库中的物料具有稳定的相关性,因此,本文考虑将具有需求关联的物料存储在同一区域,以尽可能地减少在拣选物料时所需要的区域访问次数。此外,该仓库还存在两个重要特征,即存在两类不同尺寸货架构成的两类不同容量的区域及采用严格的重物下置原则。本文建立了以最小化区域访问次数为目标的数学规划模型,给出了求解该问题的一种聚类启发式方法与自适应大邻域搜索算法(adaptive large neighborhood search,ALNS),并设计了能够反映物料关联特征的小规模和大规模算例用于测试两种算法的性能。将两个算法结果与随机策略、CPLEX求解结果对比,结果显示聚类启发式方法与ALNS在大规模算例中表现明显优于随机策略和CPLEX的求解结果。
文摘受光强变化大、照度低以及车灯光晕等影响,夜间环境下车辆视频检测相对白天比较困难;文中采用帧差法求感兴趣区域(Region of Interesting,ROI),抑制夜间车灯光晕;并引入"疑是车辆"的概念。以消除车辆断层和随机噪声造成的车辆误检;同时,根据运动目标在车道内分布的离散度判断车型;对不同夜间交通场景进行测试,检测率均在96%以上;在广深高速公路实地应用中取得了很好效果。
