Vulvectomy: Indications and Results in the General Surgery Department of the Ignace Deen Chu Hospital in Conakry

Introduction: The aim of this study was to report the indications and evaluate the results of vulvectomy in the general surgery department of Ignace Deen Hospital, CHU Conakry. Materials and Methods: This was a retrospective descriptive study, conducted over a period of five (05) years from January 1, 2018 to December 31, 2022, in the general surgery department of Ignace Deen Hospital, CHU Conakry. We included in our study all patient records in whom vulvectomy was performed. Results: We recorded 15 cases of vulvectomy out of 453 perineal surgeries, i.e. 3.31%, with a mean age of 43.56 years and extremes of 35 and 69 years. Vulvar cancer was the most common diagnosis (46.67%), followed by Buschke-Lowenstein (33.33%) and anal canal cancer extending to the vulva (20%). Six patients had undergone biopsy (40%). Vulvectomy with lymph node dissection was performed in only 9 patients (60%), and all surgical specimens were sent to anatomical pathology (100%). Conclusion: Vulvectomy is a surgical technique most often indicated for the treatment of vulvar cancer.

Diagnostic challenges from conflicting results of tests and imaging

Accurate diagnosis is the foundation of clinical care but accurate diagnosis is not easily reached in some cases.In rare instances,even a sophisticated multidisciplinary team at an academic medical center cannot reliably reach an accurate diagnosis after extensive testing and imaging,and has to wait until histological diagnosis or even autopsy results are available.The underlying reason of challenging diagnoses is mostly conflicting data from history,tests,and imaging that point to different diagnoses.In this issue of World Journal of Clinical Cases,Huffaker et al reported such a challenging case of a tricuspid mass in a patient with Li-Fraumeni syndrome.The case by Huffaker et al powerfully illustrates the occasional diagnostic challenges inherent in our current diagnostic approach and the current technology.Clinicians should realize that in rare situations,agnosticism in diagnosis is unavoidable but a treatment has to be initiated so long as the principle of primum non nocere is upheld.

Parameter calculation and result storage for phase-field simulation in α-Mg dendrite growth of Mg-5-wt% Zn alloy

Parameter calculation and result storage, as two necessary steps in phase-field simulation play an important role in ensuring the accuracy of simulation results. A strategy of parameter calculation and result storage is presented for phase-field simulation in α-Mg dendrite growth of Mg-5-wt% Zn alloy under isothermal solidification. Based on the phase diagram and empirical formulas, key parameters of the phase-field model, such as equilibrium partition coefficient k, liquidus slope m, solutal diffusion coefficient in liquid Dl, and solutal diffusion coefficient in solid Ds, can be obtained.Both structured grid method and structured point method can be used to store simulation results, but using the latter method will reduce about 60% storage space and 37.5% storage time compared with the former. Finally, convergent simulation results of α-Mg dendrite growth are obtained and they are in good agreement with the experimental results about optical micrograph, which verify the accuracy of parameters and stability of storage method.

P&T-Inf: A Result Inference Method for Context-Sensitive Tasks in Crowdsourcing

Context-Sensitive Task(CST)is a complex task type in crowdsourc-ing,such as handwriting recognition,route plan,and audio transcription.The current result inference algorithms can perform well in simple crowd-sourcing tasks,but cannot obtain high-quality inference results for CSTs.The conventional method to solve CSTs is to divide a CST into multiple independent simple subtasks for crowdsourcing,but this method ignores the context correlation among subtasks and reduces the quality of result inference.To solve this problem,we propose a result inference algorithm based on the Partially ordered set and Tree augmented naive Bayes Infer(P&T-Inf)for CSTs.Firstly,we screen the candidate results of context-sensitive tasks based on the partially ordered set.If there are parallel candidate sets,the conditional mutual information among subtasks containing context infor-mation in external knowledge(such as Google n-gram corpus,American Contemporary English corpus,etc.)will be calculated.Combined with the tree augmented naive(TAN)Bayes model,the maximum weighted spanning tree is used to model the dependencies among subtasks in each CST.We collect two crowdsourcing datasets of handwriting recognition tasks and audio transcription tasks from the real crowdsourcing platform.The experimental results show that our approach improves the quality of result inference in CSTs and reduces the time cost compared with the latest methods.

Management Results and Financial Status of Rural Collective Economy under the Background of Rural Revitalization

Based on the analysis of financial statements,the performance and problems of rural collective economic organizations in their business activities were analyzed.It is believed that rural collective economy was developing continuously in a good way,with strong debt paying ability,but the operation ability and management efficiency need to be further improved.The operation was too conservative,and the asset utilization efficiency and profitability were weak.There were many unnecessary liabilities,and they developed mainly relying on their own accumulation.Therefore,it is proposed to crack the"talent dilemma"of rural collective economic operation and management,straighten out and clarify the relationship between rural collective economic organizations and villagers self-governing organizations,correctly handle the relationship between collective accumulation and member distribution,adhere to the financial input of blood replenishment and transfusion,and make liabilities reasonable according to the management development.

Analysis of Toxicological Test Results of 580 Detergents

To evaluate the safety of detergents,the toxicological test results of 580 collected detergents were analyzed.The results showed that,in the acute oral toxicity test,94.4%and 5.6%of the samples were classified as non-toxic and toxic respectively.In skin irritation test,95.1%of the samples were mild irritation or below,and 4.9%were moderate irritation or above.In the vaginal mucosa irritation test,79.0%of the samples were very mild irritation or below,while 21.0%were mild irritation or above.In the acute inhalation toxicity test,the proportion of the samples classified as actually non-toxic and toxic were 87.9%and 12.1%respectively.In the eye irritation test,95.7%of the samples belonged to mild irritation or below,and 4.3%of the samples belonged to moderate irritation or above.The products at risk in category A,B and C products account for 6.3%,7.7%and 14.2%respectively.Of the 580 tested samples,90.9%were relatively safe,while 9.1%were at risk.These data showed that most of the tested samples meet the safety requirements for use.

Vertebroplasty and Kyphoplasty: Indications and Results, a Preliminary Senegalese Experience from the Neurosurgery Department of the CHNU of Fann

Introduction: Vertebroplasty and kyphoplasty are percutaneous techniques that consist in injecting an acrylic cement into the body of a pathological vertebra. This work aims to report the experience the of Fann’s neurosurgery department in treating certain spinal pathologies by vertebroplasty and kyphoplasty. Methods: During a 3-year period from July 1, 2019 to July 31, 2022, we conducted a retrospective, descriptive and analytical study, including patients who underwent vertebroplasty or kyphoplasty for dorsolumbar spinal pathology. Results: The mean age of the 13 patients in our study was 51.61 years. Female gender was predominant in 62% (n = 8). The context of spontaneous onset was found in six patients. Nine patients had a VAS (visual analogue scale) ≥ 8 (69.23%). On clinical examination, all patients had a syndrome without neurological deficits. 84.61% of patients had a CT scan (n = 11). The dorsolumbar hinge was most affected with 53.85% of cases. Seven patients had a vertebral compression of between 25% and. The average degree of kyphosis was 8˚ and seven patients had a degree of kyphosis ≥ 10˚. Tumour aetiology accounted for 46.15% of cases. Kyphoplasty was performed in 61.53% (n = 9) of the cases and vertebroplasty was performed in 38.47% (n = 4) of the patients. Kyphoplasty was associated with biopsy in two cases and with osteosynthesis in one patient. Vertebroplasty was always associated with a biopsy. The evolution was favourable with a significant reduction in pain and vertebral kyphosis. The mean VAS decreased from 8.15 to 0.69 three months after treatment and the mean kyphosis decreased from 8˚ to 2˚. Conclusion: Kyphoplasty and vertebroplasty as percutaneous techniques allow consolidation of the vertebral body and pain relief. Kyphoplasty alone not only reduces pain but also restores the height of the compacted vertebral body.

Results and Application of Soil and Water Conservation Monitoring in the Yellow River Basin

Since water and soil conservation monitoring in the Yellow River Basin entered a new stage at the end of the 20th century,the monitoring scope has been expanding,the monitoring accuracy has been improving,the monitoring content and indicators have been increasing,and the monitoring technology and methods have been improving.This paper mainly analyzes the status of soil and water conservation monitoring in the Yellow River Basin,as well as the construction of the monitoring system and related research,in order to provide a reference for watershed management and development and the scientific research of water and soil conservation.

成果导向下“精益”教学资源库建设模式的构建与实践

针对高职专业教学资源库建设中资源与岗位对接度不够、资源利用率不高、学习达成度评价体系不全等问题,提出了一种成果导向下的“精益”建设模式。“精益”建设模式以成果为导向,反向设计资源模块,项目式串联建设可复用颗粒化资源,精准化设置学习目标达成评价体系,教师可以基于学情数据,利用资源库资源搭建在线课程,满足不同学习者的学习需求,实现分层次差异化教学。实践表明该模式能有效服务于专业人才培养需求,高效益建设资源库资源,提高学生学习达成度,更好的服务于教师的教学需求,为职业教育资源库提供了一种参考模式。

基于STEAM理念联合PBL教学法在急诊医学教学中的应用研究

目的分析基于STEAM[S(science),T(technology),E(engineering),A(art),M(mathematics)]理念联合以问题为基础的教学法(problem base learning,PBL)在急诊医学教学中应用效果。方法选择2021年6月—2022年6月滨州医学院急诊科80名本临床医学专业实习生为研究对象,将其随机分为对照组、试验组,各40名。对照组接受传统教学,试验组接受基于STEAM理念联合PBL教学法。对比2组教学前后理论知识及实践操作考试成绩、实习生对教学的满意度、学习依从度及教学前后实习生职业特质评分。结果教学前,2组考核成绩对比,差异无统计学意义(P>0.05);教学3个月后,2组基础理论、实践操作考核成绩均明显提升,但试验组提升幅度更大,差异有统计学意义(P<0.001)。试验组实习生学习依从性(97.50%)高于对照组(85.00%),差异有统计学意义(P<0.001)。试验组教学方法、学术能力、带教态度管理质量评分高于对照组,差异有统计学意义(P<0.001)。教学前,2组实习生职业特质评分对比,差异无统计学意义(P>0.05);教学3个月后,试验组评分高于对照组,差异有统计学意义(P<0.001)。结论在急诊医学教学中,基于STEAM理念联合PBL教学法有利于提升实习生的综合能力,提高理论实践成绩和学习依从性。

高等职业院校科技成果转化工作的思考

从教育质量、成果转化率、社会责任、校外实践四个方面讨论了高等职业院校科技成果转化工作的意义。就建立成果转化体系、成果转化基金、成果转化平台和加强宣传推广四个方面为高等职业院校科技成果转化工作提出了建议思路和举措,以期为国内同类高等职业院校的科技成果转化工作提供参考。

高职“机械设计基础”课程混合式教学改革创新路径研究

基于“机械设计基础”这门课程的特点和高职学习者学情,探索“学做研创”专业基础课程改革路径,通过设计不同的产品结构设计主题,以机械产品设计为主线,有机融入“机械原理设计→机械结构设计→机械产品评价”教学方式,创新实施基于成果导向的“1+1+N”线上线下混合式教学模式,以宿舍为单位组建学习型组织,团队协作完成不同难易程度的机械作品以检验学习成果,实现“教与学、学与做、做与创”深度融合,让“学习者成为课堂主体”“教师成为课堂主导教练员”,打造高效优质金课堂。

融入区块链的课程目标达成评价系统建构与应用研究

推进课程评价数字化转型升级,是实现教育现代化、推进教育高质量发展、建设教育强国的重要举措。然而,当前课程目标达成评价领域存在中心化管理、数据孤岛、安全性不足等问题,影响了课程目标达成评价的科学性和公信力,进而制约了课程评价数字化转型。为此,文章提出一种基于区块链技术变革课程评价的新思路,设计了融入区块链的课程目标达成评价系统,从数据共享框架、课程目标达成评价合约、隐私保护方案三个层面探讨系统的运行机制,并阐述该系统的主要功能和应用成效。文章设计的系统,可为消除数据孤岛、提高评价数据安全性、推动课程评价数字化转型提供参考。

乡村振兴背景下“三阶递进”模式在农民培育中的构建和应用

要实现我国农业的现代化,确保国家粮食安全和重要农产品有效供给,就需要打造一支高素质农民队伍。基于此,江苏农牧科技职业学院创新育人体制、机制,通过构建培育资源包、开发培育模块、固化培训流程、建立质量保障体系等一系列做法,为乡村振兴培养“懂技术、善经营、会管理”的高素质农民。发展生态农业对高素质农民的需求,采用“三阶递进”高素质农民培育模式进行培育,取得了较好的培育效果,形成了高素质农民培育范式,为模式的完善和进一步推广奠定了基础。

高职临床医学应用型人才培养目标及能力目标构建——以成果为导向

以成果产出为导向,临床医学专任教师通过顶岗实践并访谈专家,研讨临床医学生胜任职业岗位应具备的能力,并结合国家标准和办学定位,明确高职临床医学应用型人才培养目标。通过对在岗医师实际工作岗位所需能力和毕业生职业岗位胜任力进行问卷调查,分析整合了高职临床医学毕业要求核心能力及指标点,构建了高职临床医学能力目标。同时,厘清每门课程与毕业要求核心能力及指标点的映射关系,汇集了支撑能力目标达成“4321”课程体系。

中国铼资源特征及其勘查开发利用现状

铼(Re)是重要的战略性新兴产业矿产,在现代国防和工业及新兴领域具有广泛的用途。本文在《中国矿产地质志·稀散金属矿卷》研编的基础上,对中国铼矿资源特征和勘查开发利用情况进行进一步总结,认为我国铼矿资源分布比较集中,具有较大的成矿潜力和找矿空间。近年来,铼的矿产勘查取得了重要成果,据不完全统计,截至2021年底,共获得铼查明资源储量787.41 t。从世界上看,铼的规模生产开始于1930年。与世界相比,中国铼工业发展并未形成规模,仍处于初级阶段,且其开发利用严重依赖寄主矿床的开发利用。借鉴国外铼资源的开发利用史,铼的应用从添加剂到催化剂到航空发动机再到量子计算,每一次技术革新都带来对铼资源需求的增长。预测未来10~20 a国内铼的应用将更加多元化,需求也将达到高峰期,铼资源保障程度有待于进一步提高。建议开展全国铼矿资源潜力评价,查明铼的可用资源量和潜力,加强铼资源综合利用和回收产业化,建立铼的战略储备机制。

中国碲资源特征及勘查开发利用现状

碲(Te)是重要的战略性新兴产业矿产资源,在现代国防和工业及新兴领域具有广泛的用途。本文在《中国矿产地质志·稀散金属矿卷》研编的基础上,对中国碲矿资源特征和勘查开发利用现状进行了系统梳理和总结,提出中国碲矿以伴生矿为主,独立碲矿床仅1个(四川大水沟);已查明碲矿资源储量集中分布在广东、江西和甘肃,3省碲资源量占全国资源总量的93.08%;伴生大型、超大型碲矿(大宝山、城门山、金川和白家咀子)具有较大的成矿潜力和找矿空间;目前,中国碲工业发展仍处于初级阶段,开发利用严重依赖于寄主矿床。随着太阳能电池、航空航天等技术的快速发展,碲矿资源需求将逐步加大,碲资源供应缺口即将来临。为了确保中国乃至全球碲资源的可持续供应,中国应加大碲资源的勘查力度,提高碲矿的提取技术,从而提高自身的碲产量和供应能力,推动碲产业的发展,减少对外依赖。这不仅有助于保障国家经济发展的需要,也有利于加速中国在碲相关产业领域的技术进步和国际竞争力的提升。

广西荔枝龙眼创新团队10年建设经验、成效与发展对策

国家现代农业产业技术体系广西荔枝龙眼创新团队于2013年启动建设。10年来团队发挥技术优势,积极开展产业调研、新品种选育及引进、产业技术研发、示范基地建设等工作,在优良新品种选育推广应用、高接换种技术、密闭园改造技术、荔枝蒂蛀虫防控技术及人才培养等方面取得了显著成效,为促进荔枝龙眼产业发展提供了技术支撑。然而,广西荔枝龙眼产业仍存在着主栽品种价格低迷、劳动力老龄化、新品种和新技术推广见效慢等问题。针对以上问题,团队进一步完善技术体系创新机制,充分调动团队成员的工作积极性,根据产业实际情况研发推广轻简实用生产技术,打破岗位职能限制,拓宽服务领域,为广西荔枝龙眼产业可持续发展提供更有力的技术支撑。

北京市某综合医院成人社区获得性肺炎病原学结果分析

目的:了解北京市某综合医院成人社区获得性肺炎的病原体分布情况,为临床诊治和疾病防控提供参考依据。方法:2018—2019年选取在北京市某综合医院感染科就诊的成人社区获得性肺炎患者,采集病例的痰液样本,采用多重实时荧光定量PCR检测方法对样本进行多种呼吸道病原体检测,分析呼吸道病原体在不同年龄段患者和不同季节中的检出情况。结果:330例社区获得性肺炎患者中,有286例患者检出呼吸道病原体,检出率为86.67%,其中检出单纯细菌感染、肺炎支原体感染、病毒感染和肺炎衣原体感染患者分别为98例、47例、16例和2例。在123例样本中检出混合病原体,检出率为37.27%。混合病原体感染中以细菌合并肺炎支原体最为多见,其次是细菌合并病毒感染。呼吸道病原体检出前3位依次为肺炎链球菌、肺炎支原体和流感嗜血杆菌。18~59岁年龄段患者肺炎支原体检出率明显高于≥60岁年龄段患者。结论:北京市某综合医院成人社区获得性肺炎患者呼吸道感染病原体以肺炎链球菌、肺炎支原体和流感嗜血杆菌为主,且混合感染率较高,临床上要重视混合病原体感染,并合理选择抗感染药物。

基于胃不和则卧不安探讨Hp相关慢性胃炎对患者睡眠的影响

目的探讨幽门螺杆菌(Hp)相关慢性胃炎对患者睡眠的影响及具体表现形式。方法通过问卷调查,对比分析Hp相关慢性胃炎及非Hp相关慢性胃炎患者睡眠的具体特点。结果Hp相关慢性胃炎男性患者总体睡眠显著优于非Hp相关慢性胃炎男性患者及Hp相关慢性胃炎女性患者,明显较非Hp相关慢性胃炎男性患者睡眠质量好、睡眠时间长、睡眠效率高,明显较Hp相关慢性胃炎女性患者睡眠质量好、入睡时间短、睡眠效率高、睡眠障碍少、催眠药物使用少(P<0.05);Hp相关慢性胃炎男性患者较Hp相关慢性胃炎女性患者明显更少出现夜间易醒或早醒、呼吸不畅、感觉冷、做噩梦及其他影响睡眠的事情,更易咳嗽或鼾声高(P<0.05);Hp相关慢性胃炎女性患者催眠药物使用显著多于非Hp相关慢性胃炎女性患者,咳嗽或鼾声高显著多于非Hp相关慢性胃炎女性患者(P<0.05)。结论Hp相关慢性胃炎患者常有睡眠异常且具有一定的性别差异。